<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation K101Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 14
Isolates 15
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK4015TK4016a AZT, 3TC, TDFEFVM184V, L210W, T215CK103NI31R, V35I, K49R, V60I, K101Q, K122E, D123S, I135L, D177E, I178M, T200A, Q207E, V245K, D250E, A272P, L282C, L283I, T286A, I293V, D324E, Q334RD
 TK4016TK4016a AZT, 3TCEFVM184V, L210W, T215CK103NI31R, V35I, K49R, V60I, K101Q, K122E, D123S, I135L, D177E, I178M, T200A, Q207E, V245K, D250E, A272P, L282C, L283I, T286A, I293V, D324E, Q334RD
Kouri (2012)CU116-10CU116-10JQ585365NRTINNRTID67DN, K70KR, M184V, T215TI, K219KEK103N, P225HV21I, V35T, T39A, E40D, K101Q, K122KE, D177E, I178M, Q207T, V245T, D250E, A272S, T286A, V292I, P313T, V317A, I329VD
Reynolds (2012)E0580E0580-2JN652206AZT, 3TC, TDF, DDINVPM184VV108I, Y181CL34I, V35T, E40D, K49R, V60I, K101Q, D121H, K122E, E169D, D177E, I178L, G196E, T200I, E204K, Q207D, R211K, H221Y, V245K, D250E, T253TA, K277R, L282C, L283I, T286I, A288S, I293V, E297AD
 G0715G0715-1JN652194AZT, 3TCEFVM184VK103NV35T, K49R, V60I, K101Q, K122KE, D123A, E169D, D177E, I178M, Q207E, R211K, D250E, A272P, K277R, L282C, L283I, R284RG, T286A, I293VD
  G0715-2JN652208AZT, 3TC, TDF, FTCEFVD67N, M184VK103N, P225HE28K, V35T, K49R, V60I, K101Q, K122E, D123A, E169A, D177E, I178L, Q207E, R211K, D250E, A272P, K277R, L282C, L283I, T286A, I293VD
 F0701F0701-1JN652190AZT, 3TCNVPM184VG190AV35T, K49R, I50T, V60I, V90I, K101Q, K122E, I132V, S162N, D177E, I178M, T200I, Q207E, V245E, D250E, A272P, K277R, L282C, T286A, I293V, E297GD
Pircher (2013)B1117B1117JX110218D4T, 3TC, AZTNVPM41L, T69D, V75M, M184V, L210W, T215YA98G, Y181CI31L, V35IT, T39A, E44D, V60I, K101Q, V106I, V118I, P119PS, D121C, K122E, S162N, Q174K, D177E, I178V, T200E, K201M, E203K, E204Q, Q207A, R211K, K223T, L228R, V245TD
Sigaloff (2013)JCR113_0JCR113_0JX182004NRTINNRTIM41L, D67N, V75VL, M184V, L210W, T215YA98G, G190AE6N, K11Q, V35T, E44D, K49R, V60I, I94L, K101Q, V111IM, D121Y, K122E, I135M, T165I, D177E, Q207E, R211K, V245Q, L282C, L283I, K287R, I293VD
Aghokeng (2014)CM-1-290CM-1-290KC350180NRTINNRTI  P4PH, E6EK, K20R, V35T, T39N, E40D, K49R, V60I, K101Q, D123E, I135T, E138A, S162C, R172K, K173Q, I178L, V179I, Q182S, T200A, K201R, E204K, Q207E, R211K, F214L, V245T, D250ED
Kityo (2017)2831528315KY061370NRTINNRTIM41L, K70R, M184V, T215V, K219QK103NSV35I, K49R, V60I, T69N, K101Q, K122E, I135M, E138Q, E169A, D177E, I178M, T200X, Q207G, R211K, V245K, D250E, A272P, K277R, L282C, L283I, T286A, A288T, I293VD
 8314783147KY061703NRTINNRTIM41L, D67N, K70R, V75M, M184V, L210W, T215Y, K219EK103N, V108IP59PS, V60I, R78R*, E79ED, K101Q, D121Y, K122E, D123G, S162C, D177E, I178L, T200I, Q207D, R211K, L228HD
 8316083160KY061716NRTINNRTID67N, K70R, M184V, T215TFIS, K219EY181YC, G190AV60I, K64R, T69TN, V90I, K101Q, I178L, V179I, Q207E, L228QD
 6605866058KY061421NRTINNRTID67N, M184V, L210W, T215YK103NK43KE, K49R, V60I, K101Q, D121H, K122E, I135K, S162N, E169D, D177E, I178L, V189I, G196GE, T200I, I202V, Q207E, R211KD
 8344983449KY062003NRTINNRTIM41L, T69D, M184V, L210W, T215YA98G, V108VI, Y181CK43E, E44A, K49R, V60I, K101Q, V118I, S162N, D177E, T200I, Q207E, R211K, L228RD