<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation K101E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 10
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK2025TK2025 D4T, 3TC, ABCNVPL74V, M184VK101E, Y181C, G190AK32R, V35M, E42EG, K43N, V60I, K122E, I135T, D177E, T200I, Q207E, R211K, V245EK, D250E, A272P, L282C, R284K, T286A, I293V, E297AD
  TK2025a D4T, 3TC, ABC, DDC, DDINVP, EFVM41L, L74VK101E, Y181C, G190AK32R, V35R, K43N, V60I, V118I, K122E, I135T, D177E, T200I, Q207E, R211K, V245K, D250E, A272P, L282C, R284K, T286A, I293V, E297A, P321PQD
Weber (2005)M94371M94371AY677521AZT, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AV60I, K122E, D177E, I178L, V179I, T200I, Q207E, R211K, V245Q, E248N, D250E, A272P, L282C, R284K, E291A, I293VD
 01F868601F8686AY677603AZT, 3TCEFV, NVPM184VK101E, G190AK20R, W24WC, V35T, T39M, K49R, V60I, V90I, K122E, D177E, I178M, T200I, Q207E, R211K, V245K, E248D, D250E, A272P, K277R, L282C, L283I, T286A, A288P, I293V, E297K, S322AD
Baxter (2006)48-41654165-30410DQ878398NRTINNRTIM41L, D67N, K70R, T215F, K219QK101E, G190SV35T, K49R, V60I, T69TN, V90I, A98S, V118I, K122E, I135T, E138A, T165I, E169D, R172RK, D177E, I178L, V179X, Q197E, E203A, Q207E, R211K, F214L, L228H, V245T, D250E, A272P, K277R, T286A, E297KR, I329L, G335D, M357MT, G359S, A376T, S379C, T386AD
Church (2008)393395X393395XEU380748NoneNVP K101EV35T, K49R, V60I, D121H, K122E, D177E, I178M, T200I, Q207E, R211K, V245K, D250E, A272P, V276I, K277R, L282C, L283I, T286A, I293V, E297K, D324DND
Hawkins (2009)R348ZZR348FJ931375AZT, 3TCNVPD67DN, K70R, M184V, K219QK101E, G190AP4T, E6KQ, E28K, K32E, V35T, T39L, V60I, V118I, K122E, I135T, I142T, D177E, I178LV, T200A, Q207E, R211K, F214L, V245K, D250E, T286A, V292I, E297R, I329VD
Ndembi (2010)DT5712_04_P15712GQ409630AZT, 3TCNVPM184VK101E, G190AV35T, T39R, K43E, K49R, V60I, I142M, R143K, N147Q, K166R, I167M, E169D, D177E, T200I, Q207E, R211KD
Aulicino (2011)ARN272RLDARN272RLDFJ525856NRTI, UnknownNNRTI, UnknownM41L, D67N, T69D, K70R, L74V, M184V, L210W, T215Y, K219HA98G, K101E, V108I, Y181C, G190AS3C, K20R, E28A, V35T, T39E, E44D, V60I, V90I, L109I, K122E, I135V, I142V, S162N, I167V, V179I, T200A, E203K, Q207E, H208Y, R211KD
Reynolds (2012)B0715B0715-1JN652173AZT, 3TCNVPM184VK101E, G190AV21VI, E28K, K32E, V35T, T39TK, V60I, K82R, K122A, I135T, D177E, T200I, Q207E, R211K, F214L, V245K, D250E, A272P, K275R, L282C, I293V, E297AD
  B0715-2JN652205AZT, 3TC, TDF, FTCNVPM184VK101E, G190AV21I, E28K, K32E, V35T, T39K, V60I, K82R, K122A, I135T, D177E, T200I, Q207E, R211K, F214L, V245K, D250E, A272P, K275R, L282C, I293V, E297AD
 C0717C0717-1JN652177AZT, 3TCEFVM184VK101E, G190SK13KN, K32R, V35I, E40D, K49KR, T58TS, V60I, D121Y, K122E, D177E, I178M, V179I, E204K, Q207E, R211K, V245Q, I257L, A272P, K277R, L282C, T286A, V292I, I293VD

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