<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation A98G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 27
Isolates 29
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patROU00_ROUX701AJ577987AZT, Unknown, DDI, 3TCUnknown, NVPM41L, D67N, K70R, M184V, T215Y, K219EA98G, V108I, Y181CV60I, L109I, I135V, S162A, K173T, Q174E, D177E, T200A, I202V, Q207E, V245A, E248K, D250ECRF02_AG
Non-B Workgroup (2005)PL3439255893AY901524D4T, DDINVP, EFVK70E, V75AA98G, K101E, Y181C, G190AV35T, K73Q, I135R, S162A, K173IT, Q174K, D177E, I178M, T200A, Q207EG, R211K, H221Y, L228R, V245Q, T286A, E291D, V292T, I293V, P294A, Y318T, S322TCRF02_AG
 PL3508557393AY9015363TC, D4T, AZTNVPM184VA98GP4S, V35T, E36D, D113DE, K122E, I135V, T139TA, A158AS, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, P243PT, V245Q, A272P, K275KR, Q278H, T286A, E291D, I293V, S322TCRF02_AG
Baxter (2006)48-12441244-30527DQ877767NRTINNRTIM41L, D67N, K70R, V75T, L210W, T215Y, K219DA98G, V179E, Y181C, G190AT27S, E28K, K32E, V35T, E36D, T39N, V60I, K64KR, K102Q, V118I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, K223E, L228H, Q242H, V245Q, D250E, K281R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357K, G359S, A360AT, A371V, I375V, T386I, K390R, K395RCRF02_AG
 48-30363036-30310DQ877947NRTINNRTID67N, T69D, K70R, M184I, K219HA98G, V108I, Y181C, G190AV35T, E36A, T39K, K46M, V60I, V90I, K101R, K122E, D123S, S162A, S163T, T165I, Q174E, D177E, T200A, E203N, Q207K, L210I, D218E, V245Q, K275KQ, K277R, T286A, E291D, I293V, P294T, E297EK, E300EQ, S322T, G335D, R356K, M357K, G359S, A360I, A371V, I375V, K390R, K395RCRF02_AG
 48-30903090-30925DQ877999NRTINNRTIM41L, D67N, T69D, K70R, L74I, M184V, L210W, T215F, K219QA98G, K103N, V108I, Y181CV35T, T39A, K49R, V60I, V90I, K122E, I135V, S162E, E169K, K173T, Q174K, D177E, I178M, T200A, E203D, Q207E, D218E, L228H, V245Q, E248D, D250E, L283I, A288T, E291D, V292I, I293V, P294T, S322T, G335D, M357Q, G359S, A371V, I375V, A376S, K390R, K395RCRF02_AG
 48-41674167-30423DQ878400NRTINNRTIM41L, D67N, M184V, L210W, T215FYA98GV35T, T39N, V60I, V118I, K122E, D123N, I135V, K173I, Q174K, D177E, T200A, Q207G, R211K, V245K, D250E, K277R, T286A, E291D, V292I, I293V, E297EA, D324E, I326V, G335D, R356K, M357R, R358K, G359S, K366KR, A371V, I375V, T377Q, K395RCRF02_AG
  4167-40203DQ878401NRTINNRTIM41L, D67N, M184V, L210W, T215FA98GV35T, T39D, V60I, V118I, K122E, D123N, I135V, K173I, Q174K, D177E, T200A, Q207G, R211K, V245K, D250E, K277R, T286A, E291D, V292I, I293V, D324E, I326V, G335D, R356K, M357R, R358K, G359S, K366R, A371V, I375V, T377Q, K395RCRF02_AG
Laurent (2006)CK2-5902CM-59AM279443AZT, 3TCEFVM41L, M184V, T215FA98G, K103NK20R, V21I, V35T, T39A, V60I, K122P, I135V, S162C, Q174R, D177E, T200A, Q207E, R211K, V245Q, K275Q, V276T, L283I, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377M, K390R, T403M, E432DCRF02_AG
Sylla (2008)A1068A1068_C2DQ991622D4T, 3TCEFVM184VA98G, K103N, P225HI31L, V35T, E40D, K49R, I50V, K122P, S162A, E169K, K173T, Q174E, D177E, I178M, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, E370G, A371V, A376S, T377M, T386I, K390R, K395R, T403M, E432D, V435I, R461K, V467I, D471E, Q480H, L491S, K512S, L517I, S519N, Q520L, Q524E, K527G, E529D, A534SCRF02_AG
 C1078C10781_C1DQ991651D4T, 3TCEFVM41L, M184V, T215YA98G, K103N, V179EK20R, E28K, V35T, E36D, K122E, I135T, I142V, S162A, E169A, K173T, Q174S, D177E, T200A, Q207E, L228R, V245Q, D250E, T286A, I293V, P294T, E312D, I326V, M357K, R358T, G359S, K366R, T369V, A371V, I375V, A376V, T386A, A400T, T403M, E432D, V435ACRF02_AG
 A2619A2619_C1EF525657AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
  A2619_C2EF525658AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
Hawkins (2009)P615ZZP615FJ931129D4T, 3TCNVPD67DG, V75T, M184V, T215YA98G, G190AV35T, E36D, T39A, E40D, K49R, S68SG, D123E, I132L, I135L, S162A, E169K, K173T, Q174E, D177E, V179VI, T200A, E203EA, Q207E, R211K, V245Q, S251N, K275R, V276T, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 P633ZZP633FJ931139D4T, 3TCNVPM184V, T215TNSYA98G, K103N, Y318FV35T, T39K, K122E, D123N, I135L, S162A, K173A, Q174K, N175Y, D177DE, T200A, Q207E, R211K, V245Q, E248D, T286A, V292I, I293V, P294T, S322T, I326VCRF02_AG
 P644ZZP644FJ931148D4T, 3TCNVPM41ML, D67N, T69AD, F77FL, Q151M, M184V, T215FA98G, Y181VV35T, E36D, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, D218E, V245Q, V276VAIT, Q278N, T286A, E291D, I293V, P294V, S322T, I326VCRF02_AG
 P645ZZP645FJ931149D4T, 3TCNVPM184VA98G, Y181CV35T, E36D, T39K, K43E, D123E, T139R, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q186ZZQ186FJ931195D4T, 3TCNVPV75I, M184VA98G, K103N, K238TV35T, E53D, I132L, S162A, K173A, Q174K, D177E, G196E, T200A, Q207E, V245E, K281R, T286TA, V292I, I293V, E297K, S322TCRF02_AG
 Q735ZZQ735FJ931245AZT, 3TCNVPD67N, K70R, M184V, T215F, K219QA98G, K103NK32R, V35T, V60I, K122E, D123N, I135M, E138Q, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, I244V, V245K, D250DE, Q278QH, T286A, E291D, I293V, P294T, L295M, S322T, I326VCRF02_AG
 R159ZZR159FJ931349AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EA98G, V108VI, V179VE, Y181C, G190GAV35T, V60I, D123E, I135IT, K173I, Q174K, D177E, T200A, E203EK, Q207E, R211K, L228LH, V245Q, E248D, D250E, S251H, T286A, K287Q, E291D, V292I, I293V, P294T, L295M, S322T, I326VCRF02_AG
 R164ZZR164FJ931352D4T, 3TCNVPD67N, K70R, L74LI, M184V, T215TFIS, K219QA98G, K101E, G190AV35T, K49R, E53D, V60I, T69N, I135V, S162AE, K166KR, K173M, Q174K, N175NY, D177E, I178IM, Q197IKMN, T200A, Q207E, R211K, L228LH, V245EK, T286A, V292I, I293V, S322T, I326VCRF02_AG
 R351ZZR351FJ931378AZT, 3TCNVPD67DN, K70KR, M184V, T215F, K219KQA98G, K103NK20R, V35T, V60I, S68SG, D123E, I135T, S162A, K173T, Q174A, D177E, G196E, T200A, Q207G, R211K, F214L, V245Q, E248D, A272P, L283I, T286A, E291D, V292I, I293V, S322TCRF02_AG
 R236ZZR236FJ931431NRTIEFV, NVPM41L, K70R, M184V, K219QA98G, K103N, V108I, Y181C, G190AV35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
Koyalta (2009)64TCHAD-64FJ688195D4T, 3TCNVPM184VA98G, K103NK49R, I135M, S162A, K173T, Q174K, D177E, T200A, Q207ECRF02_AG
Germanaud (2010)56325632 AZT, 3TCNVPM184VA98G, K103NV35T, K49R, D121H, K122E, D123N, I135L, S162A, E169K, K173T, Q174E, D177E, I178M, T200A, Q207E, V245Q, E248D, D250ECRF02_AG
Dagnra (2011)08TG.E506808TG.E5068FR715285D4T, 3TCNVPM184VA98G, K103NV35T, E40D, V60I, I135L, S162A, K166R, K173T, Q174R, D177E, G196E, T200A, Q207E, R211K, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, L295M, S322T, I326V, R356K, M357R, G359S, T369I, A371V, I375A, T377V, K390R, T403M, E415EK, E432D, V435ACRF02_AG
Fokam (2011)CIRCB-3241CIRCB-3241JQ796147AZT, 3TCNVPM184VA98G, K101H, Y181CI5M, E6K, T7R, V8P, P9Q, V10I, M16R, V35R, E36R, T39L, D123E, T139R, S162G, Q174E, D177E, T200A, Q207E, F214L, V245Q, T286A, E291D, V292I, I293V, A304E, S322T, I326V, G335DCRF02_AG
 CIRCB-9626CIRCB-9626JQ796160AZT, 3TCNVPD67N, K70R, M184V, T215TFISA98G, G190AK20R, V35LQ, E36D, T39A, K43KQ, K46KQ, K122E, D123G, S162A, K173T, Q174K, D177E, Q207E, R211K, F214FL, V245Q, E248N, T286TA, E291D, V292I, I293V, S322A, I326VCRF02_AG
 CIRCB-10124CIRCB-10124JQ796164AZT, 3TCNVPM184VA98G, K103N, V108IV35T, T39A, V90I, K122KE, D123T, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, E248D, K275Q, V276I, T286A, E291D, V292VI, I293V, P294T, E300K, S322TCRF02_AG