<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation N348I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 4
Patients 9
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Sylla (2008)B7166B7166_C2DQ991646D4T, DDI, AZT, 3TCEFVM41L, M184V, T215Y, N348IK103N, V179ET27S, E28K, K32I, V35T, E36D, T39K, K49R, V60I, K102Q, D123S, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245E, E248D, S251R, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, T403M, E432D, V435M, A446S, V467F, S468PCRF02_AG
 D635D635_C1DQ991663AZT, 3TC, D4TNVPM184V, N348IV106AV35T, E36D, K49R, D123N, I135V, T139A, I142F, S162A, T165H, K173T, Q174G, D177E, G196E, T200A, Q207E, V245Q, K277R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377V, K390R, A400T, T403M, E432D, V435ACRF02_AG
  D635_C2EF588325AZT, 3TC, D4TNVPM184V, N348IV106AV35T, E36D, T58S, I135V, T139A, I142F, S162A, T165H, K173T, Q174G, D177E, G196E, T200A, Q207E, V245Q, K277R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377V, K390R, A400T, T403M, E432D, V435ACRF02_AG
 A013A013_C2EF525644AZT, 3TCEFVM184V, N348IK103N, P225HV35T, E36D, I159L, S162A, K173T, Q174K, D177E, T200A, Q207E, V245K, E248D, D250E, S251H, A272P, K281R, T286A, V292I, I293V, P294T, R307K, S322T, I326V, G335D, R356K, M357Q, G359S, A371V, I375V, A376S, K390R, A400T, T403R, E432D, V435MCRF02_AG
 A2536A2536_C1EF525652AZT, 3TCEFVD67N, K70R, M184V, K219Q, N348IK103N, Y188LK11Q, V35T, T39L, K49R, K122E, D123N, S134R, I135V, N136I, I159L, S162A, E169Q, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243Q, V245Q, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377M, T386A, K390R, T403M, E432DCRF02_AG
  A2536_C2EF588326AZT, 3TCEFVD67N, K70R, M184V, K219Q, N348IK103N, Y188LK11Q, V35T, T39L, K49R, K122E, D123N, S134R, I135V, S162A, E169Q, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243Q, V245Q, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377M, T386A, K390R, T403M, E432DCRF02_AG
Dagnra (2011)08TG.T300308TG.T3003FR715251D4T, 3TCNVPM41ML, V75VM, M184V, T215TNSY, N348IY181CV35T, K49R, I50V, Y56YF, V60I, I135R, A158AS, S162ADE, K173T, Q174K, N175NY, D177E, T200E, Q207G, R211K, V245N, K281R, T286A, E291D, I293V, P294T, P313S, S322T, G335D, R356K, M357R, G359S, A371V, I375A, T377I, K390R, A400T, T403M, E404D, E432DCRF02_AG
 08TG.T303108TG.T3031FR715256D4T, 3TCNVPM41L, V75M, M184V, T215Y, N348IY181CV35T, K49R, I50V, V60I, I135R, A158S, S162A, K173T, Q174K, N175Y, D177E, T200E, Q207EG, R211K, V245N, K281R, T286A, E291D, I293V, P294T, P313PS, S322T, G335D, R356K, M357R, G359S, A371V, I375A, T377I, K390R, A400T, T403M, E404D, E432DCRF02_AG
 08TG.T304308TG.T3043FR715260D4T, 3TCNVPM184V, N348IK103NV35T, K49R, S162A, K173T, Q174R, D177E, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, K311R, S322T, D324E, G335D, R356K, M357K, G359S, T369V, A371V, Q373H, I375V, T377V, K390R, K395R, E396D, T403R, E432D, V435ICRF02_AG
Fokam (2011)CIRCB-10738CIRCB-10738JQ796176AZT, 3TCNVPD67N, K70R, M184V, T215F, K219Q, N348IY181CV35T, K103KR, K104R, K122E, D123S, T139R, I142V, S162A, K173T, Q174K, D177E, T200A, R211K, F214L, V245Q, E248N, S251T, T286A, E291D, V292I, I293V, P294A, S322A, I326V, Q334E, R356K, M357K, R358G, G359S, K366R, E370Q, A371V, I375V, A376SCRF02_AG
Jones (2012)178278178278JN670478NRTINNRTIN348I V8VI, V21VF, V35T, T39N, D121H, K122KE, I135T, E169D, Q174K, D177E, V179I, T200A, Q207E, R211K, V245K, K277R, T286A, E291D, V292VI, I293V, E297K, A304E, E312D, I329L, G335D, R356K, M357R, R358K, G359S, A360T, T377M, K390RCRF02_AG