<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation Y318F
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Hawkins (2009)P606ZZP606FJ931123D4T, 3TCNVPM184V, T215FK103N, Y318FK20R, V35T, S68G, I135T, K173S, D177E, T200A, Q207A, R211K, V245Q, E248N, T286A, E291D, V292I, I293V, P294TCRF02_AG
 P633ZZP633FJ931139D4T, 3TCNVPM184V, T215TNSYA98G, K103N, Y318FV35T, T39K, K122E, D123N, I135L, S162A, K173A, Q174K, N175Y, D177DE, T200A, Q207E, R211K, V245Q, E248D, T286A, V292I, I293V, P294T, S322T, I326VCRF02_AG
Charpentier (2011)CR-59CR-59FJ688265AZT, 3TCNNRTIM41L, D67N, T69D, K70KR, M184V, L210W, T215YA98G, K103N, V108VI, Y318FK20R, V35T, E36ED, T39S, E44ED, V60I, K102Q, L109LIM, V111VI, D121H, K122E, I135T, S162A, K173R, Q174N, T200A, E203EQ, Q207E, H208HY, R211K, V245Q, K275Q, K277R, L283I, E291D, V292I, I293V, P294T, E297K, S322ACRF02_AG
Sigaloff (2011)HIV103487HIV103487JN132345D4T, 3TCNVPM41L, M184V, T215YK101H, Y181C, G190A, Y318FV21I, V35T, E36D, V60I, T69A, D123E, I135L, S162A, K173A, Q174A, D177E, T200A, Q207E, V245E, S251N, A272P, L283I, T286A, E291D, V292I, I293V, P294I, S322TCRF02_AG
Rawizza (2013)LN3579LN3579KF241472NRTINNRTIM41L, D67N, T69D, K70R, M184V, T215Y, K219QA98G, K103N, Y318FV35T, E36D, E40D, V60I, D121H, K122E, I135T, E138Q, S162A, K173T, Q174K, D177E, I195L, G196E, T200A, E203K, Q207E, R211K, F214L, L228H, V245Q, E248D, D250E, K275R, T286A, E291D, V292I, I293V, P294T, E297EK, S322T, L325I, I326VCRF02_AG
Thiam (2013)2461-HALD2461-HALDJN673684NRTINNRTIM41L, M184V, T215YA98AG, K103N, Y318FV35T, T39A, I135IV, S162SC, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243T, V245Q, T286A, E291D, V292I, I293V, P294TCRF02_AG
Aghokeng (2014)TG-1-248TG-1-248KC350265NRTINNRTIA62V, V75I, M184VA98G, K103N, Y318FP4H, I31L, V35T, T39M, K122P, I135V, S162A, K173A, Q174K, D177E, T200A, I202V, Q207K, R211E, V245T, E248D, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, S379G, K390R, T403M, E432D, V435ACRF02_AG
 TG-3-587TG-3-587KC350291NRTINNRTIA62V, F116FY, Q151M, M184V, K219KEK103N, V108I, Y318FM16V, K20R, V35T, E36D, S68G, K102Q, K122P, S162A, K173T, Q174K, D177E, I178L, T200A, Q207E, F214FL, V245Q, A272P, K275Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T377I, S379C, K390R, K395R, E399D, T403M, E413DCRF02_AG