<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 11
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL55432107397 D4T, DDI, TDF, 3TCNVP, EFVK65R, M184VK103N, V108I, F227FL, M230LV35T, E36D, K49R, S68SG, K122N, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, H221Y, V245E, K275R, V276I, L283I, T286A, E291D, I293V, P294T, V317A, S322T, I326VCRF02_AG
Seyler (2007)205CS_205 AZT, 3TCEFVK70R, M184V, T215TFIS, K219QK103N, P225H, M230LV35T, E36A, T39K, K43E, K64KR, T69TAS, D123E, S162A, K173A, Q174K, D177E, T200TA, Q207A, R211K, L228R, P243H, V245QCRF02_AG
Sylla (2008)A039A039_C1DQ991617AZT, 3TCNVP, EFVM184VK103N, M230LV35T, K122Q, I135V, S162A, K173S, Q174K, D177E, V179I, Q207A, F214L, V245E, K281R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T377L, E399D, A400T, W410C, E432D, D471E, Q480H, H483Y, L491S, E492A, V496I, Q507H, Q509R, L517I, S519N, Q524K, K527E, A534SCRF02_AG
  A039_C2DQ991618AZT, 3TCNVP, EFVM184VK103N, M230L, L234IV35T, K122Q, I135V, S162A, K173S, Q174K, D177E, V179I, Q207A, F214L, H221Y, V245E, K281R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T377L, E399D, A400T, W410C, E432D, D471E, Q480H, H483Y, L491S, E492T, V496I, Q507HCRF02_AG
 A2608A2608_C1DQ991631AZT, 3TCEFV, NVPM184VK103N, Y188L, M230LV35T, K49R, V60I, S105T, I135V, S162A, K173A, Q174K, D177E, G196E, T200A, Q207E, V245Q, E248D, I257V, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, K390R, A400T, T403M, E432D, V435ACRF02_AG
  A2608_C2DQ991632AZT, 3TCEFV, NVPM184V, T215YK103N, Y188L, M230LV35T, K49R, V60I, S105T, I135V, S162A, K173A, Q174K, D177E, G196E, T200A, Q207E, V245Q, I257V, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, K390R, A400T, T403M, E432D, V435A, S468T, T470P, D471E, Q480H, L491S, K512R, S519N, Q524KCRF02_AG
 D673D673_C1DQ991672AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554N, K558RCRF02_AG
  D673_C2DQ991673AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534SCRF02_AG
Hawkins (2009)Q774ZZQ774FJ931246TDF, 3TCEFV, NVPK65R, M184IK103N, Y181C, M230LV35T, E36D, S68G, T69N, V90I, D123E, I135T, I142V, S162A, K173I, Q174K, D177E, T200A, Q207E, K220NS, H221I, Q222R, E224N, L228R, P243T, V245Q, E248EDKN, K249KQ, S251C, A272P, L283I, T286V, E291D, V292I, I293V, P294T, L295M, S322TCRF02_AG
 Q960ZZQ960FJ931289AZT, D4T, 3TCNVPK70R, L74LI, M184V, T215F, K219QK103N, V108I, M230LV35T, E36D, K64KR, T69N, V90I, K122M, S162A, K173T, Q174K, D177E, I178L, Q207E, R211K, L228Q, Q242K, V245Q, K275KR, K281KR, L283I, T286A, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R363ZZR363FJ931420TDF, 3TCNVPK65R, M184I, K219KQK103N, Y181C, M230LV35T, E36D, T39A, E40D, D123N, S162A, K173AT, Q174K, D177E, T200A, Q207E, R211K, F214L, P243Q, V245Q, E248D, K275R, R284K, T286A, E291D, V292I, I293V, P294T, K311R, S322P, I326V, Q330P, Q332P, Q334PCRF02_AG
Fokam (2011)CIRCB-7205CIRCB-7205JQ796152AZT, 3TCNVPD67N, T69D, K70R, M184V, T215F, K219QK103N, M230LV35T, T39M, K49R, K122E, D123S, S162A, K173T, Q174K, D177E, T200A, Q207S, L228H, V245Q, E248NCRF02_AG
 CIRCB-9936CIRCB-9936JQ796163AZT, 3TCNVPM184V, L210W, T215YK103N, M230LE28KR, K32E, V35T, K49R, V60I, K122E, D123N, S162A, E169A, K173A, Q174E, D177E, G196E, T200A, Q207E, R211RK, L228H, P243A, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, P294T, S322ACRF02_AG
 CIRCB-10362CIRCB-10362JQ796169AZT, 3TCNVPM184V, T215FYK103N, M230LV35M, V90I, A98S, V111VG, I135V, S162A, K173T, Q174K, D177E, T200A, Q207D, R211K, K275R, L283LI, T286A, I293V, P294T, S322A, G335DCRF02_AG