<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation F227L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 10
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Sylla (2008)D673D673_C1DQ991672AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554N, K558RCRF02_AG
  D673_C2DQ991673AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534SCRF02_AG
Hawkins (2009)Q440ZZQ440FJ931262D4T, 3TCNVPM41L, D67DN, M184V, L210W, T215YV106A, F227LV35T, K49R, L109I, V118VI, K122E, S162A, K173T, Q174K, D177E, T200A, I202V, E203K, Q207E, H208HY, H221Y, V245EK, E248D, A272P, T286A, V292I, I293V, S322TCRF02_AG
 R109ZZR109FJ931359TDF, 3TCNVPA62V, K65R, Y115F, M184VV106A, F227LT27S, K32R, V35T, T39S, K49R, W88C, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, V245K, D250E, K277R, K281R, L283I, V292I, I293V, S322A, I326VCRF02_AG
 Q998ZZQ998FJ931364AZT, D4T, 3TCNVPM41ML, D67DN, K70KR, M184V, T215Y, K219KEV106A, F227LV35T, V60I, K101Q, I135V, S162A, K173A, Q174K, D177E, T200E, E203GR, Q207D, R211K, V245T, D250E, A272P, T286A, I293V, P294T, S322TCRF02_AG
Burda (2010)06LPH20SC06LPH20SCGQ344969D4T, 3TCNVPF116Y, Q151M, M184VV108I, Y181C, F227LK20R, V35T, E36D, T39L, K49R, S68G, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, E224D, P243H, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, D320X, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403MCRF02_AG
 07BDHS07707BDHS077GQ344980D4T, 3TCNVPD67N, K70R, L74I, M184V, T215Y, K219EV106A, P225H, F227LV35T, R78P, L109I, K122E, I135V, S162A, K173I, Q174K, D177E, T200A, I202V, R211K, A272P, K275R, K277R, T286A, I293V, P294T, S322V, G335D, M357K, G359S, A371V, I375V, I382L, K390R, A400T, T403Q, E432D, V435E, A437VCRF02_AG
Germanaud (2010)55885588 AZT, 3TCNVPM184VV106A, F227LV35T, V60I, I135L, S162A, K173I, Q174K, D177E, I178V, G196E, T200A, E204G, Q207E, L209X, V245QCRF02_AG
Dagnra (2011)08TG.T306108TG.T3061FR715264D4T, 3TCNVPM184VV106A, F227LV35T, E36D, K49R, V60I, S105L, D121Y, K122E, D123E, I135V, S162A, K173T, Q174E, D177G, T200A, Q207E, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, R356K, M357R, R358K, G359S, K366R, T369V, A371V, I375V, S379G, K390R, T403M, E432D, V435LCRF02_AG
 08TG.E502408TG.E5024FR715275D4T, 3TCNVPM184VV106A, F227LK20R, V35T, V60I, V90I, K122E, D123E, I135V, S162Q, K173T, Q174K, D177E, V179I, G196E, T200A, Q207A, R211K, V245Q, A272P, K275R, T286A, E291D, V292I, I293V, P294A, G335D, R356K, M357K, G359FS, A371V, I375V, T377LS, K390R, A400T, T403M, E432D, V435ICRF02_AG
 08TG.C700308TG.C7003FR715286D4T, 3TCNVPM184VV106A, F227LV35T, L109LI, K122E, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, P243T, V245Q, T286A, E291D, S322A, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, K390R, A400AT, T403M, E432DCRF02_AG