<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation G190A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 53
Isolates 54
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patALC02_ALC723AJ577727AZT, DDI, 3TC, D4T, ABCNVPM41L, D67N, L210W, T215YK101E, G190AV35T, E36D, T39K, K43A, E44D, V60I, K104R, D121H, K122E, D123S, I135R, I142V, S162Y, K173L, D177E, I178L, V179I, Q207ACRF02_AG
 MB_patKON00_KON723AJ577921AZT, DDI, 3TC, D4T, DDC, ABCNVPM41L, L74V, M184V, T215FY181C, G190AV35T, E36A, T39K, K43E, D121H, K122E, D123S, I142V, S162F, K173S, Q174K, D177E, I178L, V179I, T200A, E203K, Q207D, H208Y, H221Y, K223NCRF02_AG
Non-B Workgroup (2005)PL3439255893AY901524D4T, DDINVP, EFVK70E, V75AA98G, K101E, Y181C, G190AV35T, K73Q, I135R, S162A, K173IT, Q174K, D177E, I178M, T200A, Q207EG, R211K, H221Y, L228R, V245Q, T286A, E291D, V292T, I293V, P294A, Y318T, S322TCRF02_AG
 PL3692269089AY901698AZT, DDI, 3TC, D4TNVPD67N, K70R, M184V, T215I, K219EG190AP4S, V35T, E36D, K43R, W88C, S134R, I135V, I142V, S162A, K173IV, Q174K, D177E, T200A, Q207E, R211K, F214L, K238KE, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 PL3275105576 AZT, 3TC, D4T, ABC, TDFNVPD67N, T69D, K70KR, M184V, T215F, K219QG190AK11R, V35T, K43Q, V60I, K122E, D123DN, I135V, S162A, K173T, D177E, T200A, E203K, Q207E, R211K, V245K, D250E, S251H, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 PL55983108809 3TC, D4T, AZTNVPM184VK103NS, G190AV35M, E36D, R83RK, D123E, I135V, S162AT, K173IT, Q174K, D177E, T200A, E203EK, Q207E, R211IK, P243PT, V245Q, T286A, E291D, V292I, I293V, S322T, K331NCRF02_AG
Baxter (2006)48-12261226-30417DQ877758NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215Y, K219EK103S, V108I, G190AP4Q, K20R, V35T, T39A, E44D, V60I, V118I, K122E, D123N, I135V, S162A, K173V, Q174K, D177E, I178M, Q197L, T200A, E203V, Q207E, K223Q, L228H, P243T, V245Q, T286A, I293V, P294T, S322A, G335D, M357K, R358K, G359S, A371V, I375V, A376T, T377M, T386A, K390R, E399DCRF02_AG
 48-12441244-30527DQ877767NRTINNRTIM41L, D67N, K70R, V75T, L210W, T215Y, K219DA98G, V179E, Y181C, G190AT27S, E28K, K32E, V35T, E36D, T39N, V60I, K64KR, K102Q, V118I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, K223E, L228H, Q242H, V245Q, D250E, K281R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357K, G359S, A360AT, A371V, I375V, T386I, K390R, K395RCRF02_AG
 48-30363036-30310DQ877947NRTINNRTID67N, T69D, K70R, M184I, K219HA98G, V108I, Y181C, G190AV35T, E36A, T39K, K46M, V60I, V90I, K101R, K122E, D123S, S162A, S163T, T165I, Q174E, D177E, T200A, E203N, Q207K, L210I, D218E, V245Q, K275KQ, K277R, T286A, E291D, I293V, P294T, E297EK, E300EQ, S322T, G335D, R356K, M357K, G359S, A360I, A371V, I375V, K390R, K395RCRF02_AG
Sylla (2008)D604D604_C1DQ991653AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EK103N, G190AE28K, K32E, V35T, V60I, K122E, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, T286A, I293V, S322T, D324E, I326V, G335D, A355S, R356K, M357K, G359S, A371V, I375V, T377Q, K390R, K395R, E396D, E413D, E432D, V466I, D471E, Q480H, L491S, Q509H, K512R, S519N, I522L, Q524K, K527E, E529D, A534S, A554SCRF02_AG
  D604_C2DQ991654AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EK103N, G190AE28K, K32E, V35T, V60I, K122E, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, T286A, I293V, S322T, D324E, I326V, G335D, A355S, R356K, M357K, G359S, A371V, I375V, T377Q, K390R, K395R, E396D, E413D, E432D, V466I, T470P, D471E, Q480H, L491S, Q509H, K512R, S519N, I522L, Q524K, K527E, E529D, A534SCRF02_AG
Hawkins (2009)P615ZZP615FJ931129D4T, 3TCNVPD67DG, V75T, M184V, T215YA98G, G190AV35T, E36D, T39A, E40D, K49R, S68SG, D123E, I132L, I135L, S162A, E169K, K173T, Q174E, D177E, V179VI, T200A, E203EA, Q207E, R211K, V245Q, S251N, K275R, V276T, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 P626ZZP626FJ931134D4T, 3TCNVPM184VA98AG, K101KE, G190A, K238KTV35T, E36D, E40D, K49R, E53D, K104T, D123E, I135V, S162A, Q174K, D177E, T200A, Q207E, V245M, E248D, T286A, E291D, V292I, I293V, E297R, S322T, I326VCRF02_AG
 Q192ZZQ192FJ931200D4T, 3TCNVPM184VK101E, G190AV35T, D123E, S162A, K173T, Q174E, D177E, I178L, T200A, Q207D, R211K, F214FL, V245Q, A272P, K275Q, K277R, K281R, L283LF, T286A, E291D, I293V, P294T, S322T, I326VCRF02_AG
 Q226ZZQ226FJ931219D4T, 3TCNVPK65R, K70KT, V75I, F77L, F116Y, Q151MY181C, G190AV35T, E36D, K49R, S68G, V90I, K101KT, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, P243PS, V245PQ, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q833ZZQ833FJ931236D4T, 3TCNVPD67DG, M184VK101KE, Y181C, G190AV35T, V90VI, K122E, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, L228LR, P243T, V245Q, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 Q580ZZQ580FJ931240D4T, 3TCNVPM184MVG190AE28A, V35T, E36D, T39N, E40D, K49KR, V60I, T139K, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, T286A, V292I, I293V, S322TCRF02_AG
 Q829ZZQ829FJ931258D4T, 3TCNVPK65R, T69~, K219RK101E, Y181C, G190AL34LI, V35T, E36D, K49R, V90VI, K122E, I135V, S162A, E169Q, K173T, Q174K, D177E, T200A, Q207E, L228LHR, V245M, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q453ZZQ453FJ931264D4T, 3TCNVPK70R, M184VA98AG, K101E, G190AV21I, V35K, V60I, I135IV, S162SA, K173T, Q174K, D177E, I178V, V179I, T200A, Q207E, R211K, V245E, T286A, E291D, V292I, I293V, P294T, S322T, I326IV, I329VCRF02_AG
 Q430ZZQ430FJ931265D4T, 3TCNVPM184VK101E, G190AE28EA, V35T, E36D, Q85QE, I135V, S162A, K173T, Q174K, D177E, I178L, G196E, T200A, E203EG, Q207E, V241VI, P243T, V245Q, K281R, T286TA, E291D, I293V, S322A, I326VCRF02_AG
 Q438ZZQ438FJ931267AZT, D4T, 3TCNVPM41ML, D67DN, M184V, L210W, T215YA98AG, K101E, G190AE28K, V35T, T39E, S48T, V60VI, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, V179VI, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, S322T, D324ECRF02_AG
 Q942ZZQ942FJ931274D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AK20R, E28K, A33AG, V35I, V60VI, V90I, K102Q, I135IT, S162A, K173T, Q174K, T200A, Q207E, D218DE, L228LH, V245Q, D250E, K275R, V276VI, T286A, E291D, V292VI, I293V, P294T, S322TCRF02_AG
 Q944ZZQ944FJ931288D4T, 3TCNVPD67DN, K70R, M184V, K219QK101E, G190AP4S, V35T, V60I, K64R, V90I, I135V, E138A, S162A, K173T, Q174K, D177E, V179M, T200A, Q207D, R211K, D218DE, V245K, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R59ZZR59FJ931299TDF, 3TCNVPK65KR, M184V, K219EY181C, G190AV35T, E36D, V60I, K101X, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, L228LR, P243A, V245E, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R65ZZR65FJ931302TDF, 3TCNVPK65R, M184VK101E, Y181C, G190AV35T, S68N, V90VI, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, L295M, S322ATCRF02_AG
 R119ZZR119FJ931315D4T, 3TCNVPD67N, M184VG190AV35T, V60I, D121A, K122E, I135V, S162AT, K173T, Q174S, D177E, I178F, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R146ZZR146FJ931329D4T, 3TCNVPM41L, D67N, T69D, K70R, V75VM, M184V, T215F, K219QY181C, G190AV35T, V60I, L109I, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207E, H208Y, R211K, D218E, L228H, V245DN, K281R, T286TA, E291D, V292I, I293V, P294T, S322A, I326VCRF02_AG
 R125ZZR125FJ931333AZT, D4T, 3TCNVPD67DN, K70KR, M184V, T215TFISK101E, G190AK11T, K20KR, E28K, V35T, V60I, V106VI, D121H, K122E, D123S, I135M, S162A, K173T, Q174K, D177E, I178FL, T200A, Q207E, R211K, V245T, A272P, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 Q772ZZQ772FJ931342AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EQK103N, G190AP4S, K20KR, V35T, K122E, D123E, I135V, S162A, K173S, Q174K, D177E, Q207A, R211E, V245Q, A272P, K275R, R284RK, T286A, V292T, I293V, P294T, S322T, I326VCRF02_AG
 R164ZZR164FJ931352D4T, 3TCNVPD67N, K70R, L74LI, M184V, T215TFIS, K219QA98G, K101E, G190AV35T, K49R, E53D, V60I, T69N, I135V, S162AE, K166KR, K173M, Q174K, N175NY, D177E, I178IM, Q197IKMN, T200A, Q207E, R211K, L228LH, V245EK, T286A, V292I, I293V, S322T, I326VCRF02_AG
 R211ZZR211FJ931367TDF, AZT, D4T, 3TCEFVM184V, T215FK103N, V179E, G190AK20R, V35T, K49R, V60I, L109LI, D121Y, K122E, D123DE, I135V, S162D, K173T, Q174K, D177E, G196K, T200A, E203D, Q207E, R211K, V245VEKM, K275R, K277R, Q278E, T286A, E291D, V292I, I293V, P294T, E298G, S322T, I326VCRF02_AG
 R215ZZR215FJ931368AZT, 3TCEFVM41L, D67N, K70R, V75VL, M184V, L210W, T215F, K219EK101E, V108I, Y181C, G190AV35IT, E36D, T39TA, K43Q, V60I, D123E, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, L228H, P243H, V245E, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R353ZZR353FJ931379TDF, 3TCNVP G190AV35T, V60I, K122P, I135V, S162A, F171Y, K173A, Q174K, D177E, I178V, T200A, Q207E, R211K, F214L, V245Q, E248D, K275Q, V276I, T286A, E291D, V292I, I293V, P294T, S322A, I326VCRF02_AG
 R224ZZR224FJ931383D4T, 3TCEFV, NVPD67DN, K70R, M184V, K219KQK101E, K103NS, G190AE28EK, V35T, V60I, K122E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, K201KRT, Q207K, R211A, V245K, T286A, V292I, I293V, P294T, S322A, I326VCRF02_AG
 R469ZZR469FJ931393D4T, 3TCNVPM41L, D67DG, T69TADN, M184V, T215YK101E, V108I, Y181C, G190AE28R, K32E, V35T, E36D, E44ED, K49R, E53D, V60VI, V90I, L109I, I135V, S162A, K173T, Q174E, D177E, I178IM, T200A, E203ED, Q207EK, H208HY, R211K, W212WR, H221HY, V245K, A272P, K281R, T286A, E291D, V292I, I293V, E297Q, S322T, I326VCRF02_AG
 R357ZZR357FJ931414NRTIEFVD67DN, K70R, M184V, T215TFISA98AG, K101H, Y181C, G190AP4S, V35T, D123E, I135V, S162A, K173T, Q174E, D177E, T200A, E204K, Q207E, R211K, F214L, K219G, H221Y, P243T, V245Q, A272P, K281KR, T286TA, E291D, V292VI, I293V, S322T, I326VCRF02_AG
 R236ZZR236FJ931431NRTIEFV, NVPM41L, K70R, M184V, K219QA98G, K103N, V108I, Y181C, G190AV35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R268ZZR268FJ931444AZT, 3TCNVPM184VK101E, G190AK11A, V35T, E36A, T39K, K43E, D123N, E138EA, I142V, S162AT, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207K, R211N, V245E, D250E, S251H, K281R, T286A, E291D, V292I, I293V, P294T, P313S, V317G, S322T, I326VCRF02_AG
 R444ZZR444FJ931455D4T, 3TCNVPA62V, V75IT, M184VK101E, G190AI31L, V35T, E36D, T39N, E53D, D123E, I132IV, E138A, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291ED, I293V, P294PT, S322TCRF02_AG
 R447ZZR447FJ931457AZT, 3TCNVPM184V, T215YA98AG, K101E, G190AE6N, E28K, K32E, V35T, E36A, T39K, K43E, K64R, D123E, I135V, S162T, Q174T, D177E, T200A, Q207E, R211K, V245Q, E248N, A272P, K275R, V276T, L283I, T286A, E291ED, I293V, P294T, L295M, S322T, I326VCRF02_AG
 R448ZZR448FJ931458AZT, 3TCNVPD67DN, K70KR, M184V, K219QG190AV35T, V60I, I135V, S162A, K173T, Q174E, D177E, T200A, Q207N, R211K, F214L, V245Q, E248D, K277R, K281R, T286A, E291D, V292I, I293V, P294TCRF02_AG
 R450ZZR450FJ931460AZT, 3TCNVPM184VK101E, G190AE28K, K32E, V35T, T39K, A98AS, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, E248D, A272P, K275R, L279IM, T286A, E291D, V292I, I293V, P294T, K311KR, S322A, I326IVCRF02_AG
Koyalta (2009)19TCHAD-19FJ688178D4T, 3TCNVPM184VG190AD121Y, K122E, D123G, S162A, K173T, Q174K, D177E, Q207A, R211NCRF02_AG
Burda (2010)LPH02NJMLPH02NJMGQ344973D4T, 3TCNVPM184VK103S, G190AV35T, S48E, V60I, I135V, S162A, K173I, Q174K, D177E, I178M, T200A, Q207E, V245T, W252G, A272P, V276I, L282X, L283X, T286A, V292I, I293V, G335S, Y339W, R356K, K390R, T403M, V435ACRF02_AG
Germanaud (2010)55745574 AZT, 3TCNVPM184VG190AT27S, V35T, E36D, T39L, V90I, I135M, S162A, E169Q, K173T, Q174E, D177E, T200A, E203K, Q207E, R211K, K220RCRF02_AG
 56005600 AZT, 3TCNVPM184VK103N, Y181C, G190AL26W, V35T, E40D, V60I, V90I, K101Q, I135V, S162A, K173A, Q174K, D177E, Q207E, V245QCRF02_AG
 56655665 AZT, 3TCNVPM184VV106M, G190AV35T, E36D, V90I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, E248DCRF02_AG
Dagnra (2011)08TG.T302908TG.T3029FR715255D4T, 3TCNVPM184VK101E, G190AV35K, K122P, I135IT, S162A, E169D, K173A, Q174K, D177E, G196GE, T200A, Q207E, F214L, V245Q, A272P, T286V, E291D, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, K390R, K395R, A400AT, T403M, E432DCRF02_AG
 08TG.T304108TG.T3041FR715258D4T, 3TCNVPM184VK101E, G190AM16MK, I31IK, V35T, V60I, S68G, K122E, I135V, S162A, K173I, Q174K, D177E, T200A, Q207G, R211N, T286A, I293V, P294T, E312D, I326V, Q334M, G335D, M357R, G359T, V365I, T369V, A371V, I375V, A376V, T386TA, A400T, T403M, W410Y, E432DCRF02_AG
 08TG.T304908TG.T3049FR715263D4T, 3TCNVPV75I, M184VV108VI, G190AV35T, E36D, V60I, K101Q, D123E, I132L, I135V, S162A, Q174D, D177K, T200A, Q207E, L210M, R211K, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357R, G359S, A360T, V365VI, A371V, I375V, A376AG, S379SG, K390R, K395R, W402WC, T403M, E432DCRF02_AG
 08TG.T306908TG.T3069FR715266D4T, 3TCNVPD67G, T69D, K70R, M184V, K219QY181C, G190AK20R, V35T, V60I, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, H221Y, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, T377V, K390R, A400T, E432DCRF02_AG
 08TG.C702408TG.C7024FR715292D4T, 3TCNVPD67G, T69D, K70R, M184V, K219QY181C, G190AK20R, E28EK, V35T, V60I, R78RK, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, F214FL, H221Y, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, T377V, K390R, A400T, E432D, V435TCRF02_AG
Fokam (2011)CIRCB-9626CIRCB-9626JQ796160AZT, 3TCNVPD67N, K70R, M184V, T215TFISA98G, G190AK20R, V35LQ, E36D, T39A, K43KQ, K46KQ, K122E, D123G, S162A, K173T, Q174K, D177E, Q207E, R211K, F214FL, V245Q, E248N, T286TA, E291D, V292I, I293V, S322A, I326VCRF02_AG
 CIRCB-11835CIRCB-11835JQ796182AZT, 3TCNVPM184VK101E, G190AE28K, V35T, E36D, T39K, K43KE, K104R, K122E, D123DG, I142V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, F214L, V245L, T286A, E291D, I293V, S322A, I326VCRF02_AG

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