<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V179I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 20
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2001)SE816SE816AF388160NoneNVP  V35T, K49R, V60I, D121H, K122E, D123E, I135T, K173S, Q174K, D177E, V179I, I195M, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294T, E312DCRF02_AG
Holguin (2003)SP_LP22SP_LP22AF455663NRTINNRTIM184V A33H, L34S, V35T, E36D, T69N, V106I, K122E, D123S, I135T, I142V, S162Y, K173S, D177E, V179I, Q207A, R211K, K220RCRF02_AG
Montes (2004)MB_patALC02_ALC723AJ577727AZT, DDI, 3TC, D4T, ABCNVPM41L, D67N, L210W, T215YK101E, G190AV35T, E36D, T39K, K43A, E44D, V60I, K104R, D121H, K122E, D123S, I135R, I142V, S162Y, K173L, D177E, I178L, V179I, Q207ACRF02_AG
 MB_patKON00_KON723AJ577921AZT, DDI, 3TC, D4T, DDC, ABCNVPM41L, L74V, M184V, T215FY181C, G190AV35T, E36A, T39K, K43E, D121H, K122E, D123S, I142V, S162F, K173S, Q174K, D177E, I178L, V179I, T200A, E203K, Q207D, H208Y, H221Y, K223NCRF02_AG
Non-B Workgroup (2005)TK2003TK2003 AZT, 3TC, DDI, ABCEFVL74LV, M184VL100LI, K103NE6D, V35I, V60I, S68G, T139K, S162A, K173T, Q174K, D177E, I178V, V179I, G196E, T200A, Q207E, V241A, P243T, V245Q, T286A, E291ED, I293V, P294TCRF02_AG
  TK2003a AZT, 3TC, DDI, ABCEFVL74V, M184VL100I, K103NE6D, V35I, V60I, S68G, T139K, S162A, K173T, Q174K, D177E, I178V, V179I, G196E, T200A, Q207E, P243T, V245Q, T286A, E291D, I293V, P294T, G316E, S322A, I326VCRF02_AG
Seyler (2007)474CS_474 AZT, D4T, 3TC, DDIEFV  I5V, E6EDHQ, V35T, E36D, V60VI, K122E, D123S, I135V, A158AS, S162A, K173S, Q174K, V179I, G196GE, T200A, I202V, Q207A, R211RS, V245QCRF02_AG
Sylla (2008)A039A039_C1DQ991617AZT, 3TCNVP, EFVM184VK103N, M230LV35T, K122Q, I135V, S162A, K173S, Q174K, D177E, V179I, Q207A, F214L, V245E, K281R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T377L, E399D, A400T, W410C, E432D, D471E, Q480H, H483Y, L491S, E492A, V496I, Q507H, Q509R, L517I, S519N, Q524K, K527E, A534SCRF02_AG
  A039_C2DQ991618AZT, 3TCNVP, EFVM184VK103N, M230L, L234IV35T, K122Q, I135V, S162A, K173S, Q174K, D177E, V179I, Q207A, F214L, H221Y, V245E, K281R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T377L, E399D, A400T, W410C, E432D, D471E, Q480H, H483Y, L491S, E492T, V496I, Q507HCRF02_AG
Hawkins (2009)Q190ZZQ190FJ931198D4T, 3TCNVPM184V, T215FY181II31L, V35T, E36A, T39A, S162A, K173I, Q174K, D177E, I178M, V179I, G196E, T200A, Q207E, V245E, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 Q453ZZQ453FJ931264D4T, 3TCNVPK70R, M184VA98AG, K101E, G190AV21I, V35K, V60I, I135IV, S162SA, K173T, Q174K, D177E, I178V, V179I, T200A, Q207E, R211K, V245E, T286A, E291D, V292I, I293V, P294T, S322T, I326IV, I329VCRF02_AG
 Q434ZZQ434FJ931266D4T, 3TCNVPM184VA98AG, V108I, Y181CV35I, V60VI, I135V, S162A, K173T, Q174K, D177E, V179I, V189I, T200A, I202V, Q207E, R211K, T215X, V245Q, E248DN, S251H, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q959ZZQ959FJ931272D4T, 3TCNVPM184VY181CK11KR, V35K, T39TA, K49KR, K102KR, K122E, D123E, I135T, S162A, K173A, Q174K, N175Y, D177E, V179I, T200A, Q207E, R211K, L228LR, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R236ZZR236FJ931431NRTIEFV, NVPM41L, K70R, M184V, K219QA98G, K103N, V108I, Y181C, G190AV35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
Burda (2010)07LPH01SG07LPH01SGGQ344976NoneEFV  V35T, F77S, K122A, S162A, K173T, Q174K, D177E, I178V, V179I, T200A, Q207E, V245Q, A272X, T286A, E291D, V292I, I293V, S322A, R356K, M357K, G359S, A371V, I375V, A376S, K390R, T403M, E432D, V435ACRF02_AG
Aghokeng (2011)SK8020-M18SK8020-M18HQ864454D4T, 3TCNVPM184V, T215TNSYY181CV35T, K43KN, K49R, S68SG, K122KE, I135V, S162D, K173I, Q174K, V179I, T200A, Q207E, R211K, H221Y, P243T, V245Q, K281R, T286A, E291D, V292I, I293V, P294TCRF02_AG
Charpentier (2011)58CP 001 381 D4T, 3TCNVPM184VY181CP4S, V8I, V35T, E40D, K102Q, V118I, I135V, K173A, Q174K, D177EK, V179I, T200A, Q207E, R211K, F214L, F227FV, L228R, V245Q, A272P, K281R, T286A, E291A, V292I, I293V, L295M, E297V, L301M, I329LCRF02_AG
Dagnra (2011)08TG.T303908TG.T3039FR715257D4T, 3TCNVPM184VY181VV35T, E36A, T39K, K43E, D121H, I142V, A158T, S162A, K173S, Q174K, I178L, V179I, G196E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, S322A, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376I, T403M, W410C, E413D, E432D, I434MCRF02_AG
 08TG.E502408TG.E5024FR715275D4T, 3TCNVPM184VV106A, F227LK20R, V35T, V60I, V90I, K122E, D123E, I135V, S162Q, K173T, Q174K, D177E, V179I, G196E, T200A, Q207A, R211K, V245Q, A272P, K275R, T286A, E291D, V292I, I293V, P294A, G335D, R356K, M357K, G359FS, A371V, I375V, T377LS, K390R, A400T, T403M, E432D, V435ICRF02_AG
Fokam (2011)CIRCB-10613CIRCB-10613JQ796174AZT, 3TCNVPM184V, T215YK103NP1PA, K11T, I31L, V35IT, T39K, K43E, E44ED, K49KR, V90I, K122E, D123G, E138G, S162A, K173T, Q174K, D177E, V179I, T200A, I202V, Q207A, L210LMPT, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, S322ACRF02_AG
Jones (2012)178278178278JN670478NRTINNRTIN348I V8VI, V21VF, V35T, T39N, D121H, K122KE, I135T, E169D, Q174K, D177E, V179I, T200A, Q207E, R211K, V245K, K277R, T286A, E291D, V292VI, I293V, E297K, A304E, E312D, I329L, G335D, R356K, M357R, R358K, G359S, A360T, T377M, K390RCRF02_AG
Mollan (2012)MK252MK252w75 TDF, FTCEFVK65RK101E, G190AP4S, V35T, E36D, V60I, K122E, D123E, I135R, S162Y, K173S, Q174K, D177E, V179I, T200A, Q207E, R211KCRF02_AG