<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V179E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 30
Isolates 34
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL5219498672 3TC, D4TEFVD67N, T69D, K70R, M184V, K219QK103N, V179E, K238TK20R, V35T, E36A, V60I, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, F214L, V245Q, S268C, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
Baxter (2006)12-31973197-30821DQ880374NRTINNRTID67G, T69DV179E, Y181IT39A, V60I, S68G, K122KE, E138A, S162A, K173T, Q174K, N175Y, T200A, Q207E, R211K, F214L, H221Y, V245QCRF02_AG
  3197-40128DQ880375NRTINNRTID67G, T69D, K70R, M184MV, T215FV179ET39A, V60I, S68SG, K122KE, E138A, T139TM, S162A, K173T, Q174K, N175Y, Y181X, T200A, Q207E, R211K, F214L, H221HY, V245QCRF02_AG
 48-12441244-30527DQ877767NRTINNRTIM41L, D67N, K70R, V75T, L210W, T215Y, K219DA98G, V179E, Y181C, G190AT27S, E28K, K32E, V35T, E36D, T39N, V60I, K64KR, K102Q, V118I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, K223E, L228H, Q242H, V245Q, D250E, K281R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357K, G359S, A360AT, A371V, I375V, T386I, K390R, K395R, A400TCRF02_AG
 48-50755075-30807DQ878585NRTINNRTIM41L, D67N, L210W, T215YV179E, Y188LV35T, K43E, E44A, V60I, K104R, V118I, K122E, I135T, K173A, Q174K, D177E, G196E, T200A, E203A, Q207D, R211K, V245Q, A272P, K275KR, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359S, A371V, K390R, K395R, A400TCRF02_AG
Delgado (2008)GH_027GH_027EU177903NoneNVP V179EE28EG, V35T, V60I, S162A, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294TCRF02_AG
Sylla (2008)B7166B7166_C1DQ991645D4T, DDI, AZT, 3TCEFVT215YK103N, V179ET27S, E28K, K32I, V35T, E36D, T39K, K49R, V60I, K102Q, D123S, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, L228R, V245E, E248D, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, A400V, T403M, E432D, V435MCRF02_AG
  B7166_C2DQ991646D4T, DDI, AZT, 3TCEFVM41L, M184V, T215Y, N348IK103N, V179ET27S, E28K, K32I, V35T, E36D, T39K, K49R, V60I, K102Q, D123S, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245E, E248D, S251R, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, T403M, E432D, V435M, A446S, V467F, S468PCRF02_AG
 C1078C10781_C1DQ991651D4T, 3TCEFVM41L, M184V, T215YA98G, K103N, V179EK20R, E28K, V35T, E36D, K122E, I135T, I142V, S162A, E169A, K173T, Q174S, D177E, T200A, Q207E, L228R, V245Q, D250E, T286A, I293V, P294T, E312D, I326V, M357K, R358T, G359S, K366R, T369V, A371V, I375V, A376V, T386A, A400T, T403M, E432D, V435ACRF02_AG
  C10781_C2DQ991652D4T, 3TCEFVM41L, M184V, T215YK103N, V179EK20R, E28K, V35T, K122E, I135T, I142V, S162A, E169A, K173T, Q174S, D177E, T200A, E203K, Q207E, K223Q, L228R, V245Q, D250E, T286A, I293V, P294T, E312D, I326V, M357K, R358T, G359S, K366R, T369V, A371V, I375V, A376V, T386A, A400T, T403M, E432D, V435ACRF02_AG
 A2619A2619_C1EF525657AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
  A2619_C2EF525658AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
Hawkins (2009)R67ZZR67FJ931303TDF, 3TCNVPK65R, M184VV179E, Y181CK20R, V35T, T39K, K43E, K49R, V60I, K102KQ, D123E, F171Y, K173T, Q174K, D177E, T200A, I202IV, Q207E, V245K, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R132ZZR132FJ931328TDF, 3TCEFVL74I, M184VK103N, V179E, P225HK20R, V35T, E36D, V60I, D123E, I135V, E138G, S162A, K173I, Q174K, D177E, I178L, T200A, R211K, P243T, V245Q, E248D, K277R, T286A, E291D, V292I, I293V, P294T, L295M, S322TCRF02_AG
Burda (2010)06ARC03606ARC036GQ344989D4T, 3TC, AZTNVP, EFVM184VK103N, V179E, Y181C, G190AV35T, K43N, K49R, I135V, S162D, E169A, K173A, Q174K, D177E, I178MCRF02_AG
Charpentier (2011)CR-8CR-8FJ688214AZT, 3TCNNRTI V179EK20KR, V35Q, V60I, K102E, K122E, D123S, E138A, I142IV, A158AS, S162SACG, T165TI, K173A, Q174K, D177E, I178MV, T200A, Q207D, V245K, T286A, E291D, V292I, I293V, P294T, S322ACRF02_AG
Kebe (2013)SNA3-286SNA3-286JN193498NRTIEFVK70KR, M184VV179E, Y188LK20R, V35T, T39M, V60I, D123E, I135V, I142V, S162A, K173T, Q174K, D177E, S191SF, T200A, Q207E, R211K, F214LCRF02_AG
 SNA3-234SNA3-234HM002532NRTINVPM184VA98G, V179E, Y181CV35T, V60I, K102N, I135V, S162A, K173T, Q174N, D177E, T200A, Q207E, V245QCRF02_AG
Theys (2013)93309330KC219686NRTI, TDFNNRTIM41L, M184V, T215FV179E, Y188LV90I, V106I, K122E, I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LCRF02_AG
Theys (2013)143390143390 AZT, 3TCEFVD67G, T69D, K70R, M184V, T215YV179E, Y181C, G190AV21I, V35T, E36D, T39A, K46KQ, S68G, V90I, K101Q, K103R, L109I, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, A288G, E291D, V292I, I293V, P294A, S322T, I326VCRF02_AG
Thiam (2013)2750-HALD2750-HALDJN673612NRTINNRTI K103KN, V108VI, V179EV35T, E36ED, V60I, S68SG, V90VI, L109LI, K122KPQT, D123E, I135V, E138A, S162A, T165L, K173T, Q174R, D177E, T200A, Q207D, R211K, F214FL, V245Q, E248D, A272P, V276I, K277R, L283I, T286A, E291D, I293V, P294T, V317A, S322T, I326VCRF02_AG
 2594-HALD2594-HALDJN673691NRTINNRTID67N, K70G, M184V, T215IV, K219QK103N, V179E, K238TV35T, T39N, V60I, K64R, V90I, K122E, D123N, I135T, E138A, S162A, T165L, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K275R, T286A, A288T, E291D, V292I, I293V, P294T, S322T, D324DE, I326VCRF02_AG
Aghokeng (2014)TG-2-417TG-2-417KC350078NRTINNRTIM184IVV108I, V179E, Y181CK20R, K22R, V35T, T39A, E40D, K122P, D123E, I135V, S162A, K173T, Q174K, D177E, Q197QL, T200A, Q207E, F214FL, V245Q, A272P, K277Q, Q278K, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, T377L, K390R, A400T, T403M, E432DCRF02_AG
 TG-5-189TG-5-189KC350306NRTINNRTIM184VV179E, Y181CK20KR, V21VI, V35T, T39L, K102Q, I135T, S162A, K173A, Q174N, D177E, T200A, Q207E, H221Y, P243T, V245Q, E248D, K275Q, T286A, E291D, I293V, P294T, E297K, S322T, G335D, R356K, M357K, G359S, T377L, K390R, A400AITVCRF02_AG
 CI-1-114CI-1-114KC350035NRTINNRTIT215YK103N, V179E, Y181CV35T, T39L, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, H221Y, V245ECRF02_AG
 CI-1-643CI-1-643KC350411NRTINNRTI V179EV35T, T39A, E40D, K122PQ, I135M, E138A, S162A, E169EDG, K173AT, Q174K, G196E, T200A, Q207E, R211K, F214L, V245QCRF02_AG
 CM-3-174CM-3-174KC350357NRTINNRTIM184VV179E, Y181CV21VI, V35T, E36D, T39A, T69N, V90VI, K122P, I135V, A158S, S162A, Q174A, D177E, T200A, Q207E, R211RK, V245Q, E248D, A272P, Q278HY, K281R, T286A, E291ED, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
 TG-1-011TG-1-011KC350200NRTINNRTIM41L, D67N, K70KR, M184V, T215F, K219KQA98G, V179E, Y188LK32Q, V35K, K103R, K122P, I135T, S162A, K173T, Q174K, D177E, I178V, T200A, I202V, E204K, Q207E, R211K, F214L, V245Q, Q278H, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A376S, T377L, K390R, E396D, A400AITV, E432DCRF02_AG
 TG-5-478TG-5-478KC350302NRTINNRTIM41L, L74V, M184V, L210W, T215YV106A, V179E, F227LK20R, V35T, E36D, L109I, V118I, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, E203K, Q207D, H208Y, R211K, H221Y, V245K, K281R, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, A376S, K390R, E399D, A400T, T403TM, E432DCRF02_AG
 CM-1-343CM-1-343KC350183NRTINNRTIK70R, M184VV179E, Y188LV35T, T39A, E40D, K46Q, K49R, I50V, V60I, T69N, V106I, I142V, S162AD, K173V, Q174K, D177E, I178IM, T200A, Q207A, R211K, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, S322A, G335DCRF02_AG
Jenabian (2015)DR25DR25KF735831NRTINNRTIK219RK103N, V179E, P225H, K238TV35T, T39L, V60VI, V90I, K122E, D123N, I135V, E138G, S162A, T165I, K173T, Q174K, D177E, T200TA, Q207E, D237N, V245Q, T286A, E291D, V292I, I293V, P294V, S322T, I326V, G335DCRF02_AG
Lam (2016)2101200621012006KR867960TDF, FTCEFVK65R, M184VV179E, Y188LK20KR, E28A, V35T, E36D, V60I, S68G, V106I, K122V, I135V, S162A, K173I, Q174K, D177E, T200E, E203K, Q207E, R211K, P243T, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
 2101201421012014KR867788TDF, FTCNVPK65R, Y115F, M184V, K219KEV179E, Y181CV35T, E40ED, K49R, V60I, S68N, D121H, K122E, S162A, T165TA, E169D, Q174R, D177E, T200A, Q207EG, R211K, F214L, V245N, A272P, T286A, I293V, P294T, S322T, I326V, G335DCRF02_AG
 2103200721032007KR868131AZT, 3TCNVPD67DN, K70KR, M184MV, T215TFIS, K219KQA98AG, K103KN, V179EE28K, V35T, E36ED, K43KR, D123E, I135V, E138EQ, T139A, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, L228LM, V245Q, V276VI, Q278N, T286A, E291D, V292I, I293V, P294T, S322AT, G335DCRF02_AG