<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V108I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 29
Isolates 31
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patSCHE02_SCHE715AJ578156D4T, DDINVPM41L, T215YV108I, Y181CP4S, V35T, E36D, V90I, K104R, K122E, I135V, S162A, E169G, K173A, Q174K, D177E, I178M, V189I, T200A, Q207E, R211K, H221Y, F227ICRF02_AG
 MB_patROU00_ROUX701AJ577987AZT, Unknown, DDI, 3TCUnknown, NVPM41L, D67N, K70R, M184V, T215Y, K219EA98G, V108I, Y181CV60I, L109I, I135V, S162A, K173T, Q174E, D177E, T200A, I202V, Q207E, V245A, E248K, D250ECRF02_AG
Non-B Workgroup (2005)PL5171397428 3TC, D4TNVP, EFVM184VK103KN, V108I, V179VE, Y181CK20KR, V35T, A98S, D123E, I135T, S162A, E169D, K173R, Q174A, D177E, T200A, Q207E, R211K, F214L, L228R, V245Q, A272P, T286A, E291D, V292I, I293V, E297A, I329LCRF02_AG
 PL55432107397 D4T, DDI, TDF, 3TCNVP, EFVK65R, M184VK103N, V108I, F227FL, M230LV35T, E36D, K49R, S68SG, K122N, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, H221Y, V245E, K275R, V276I, L283I, T286A, E291D, I293V, P294T, V317A, S322T, I326VCRF02_AG
Baxter (2006)48-12261226-30417DQ877758NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215Y, K219EK103S, V108I, G190AP4Q, K20R, V35T, T39A, E44D, V60I, V118I, K122E, D123N, I135V, S162A, K173V, Q174K, D177E, I178M, Q197L, T200A, E203V, Q207E, K223Q, L228H, P243T, V245Q, T286A, I293V, P294T, S322A, G335D, M357K, R358K, G359S, A371V, I375V, A376T, T377M, T386A, K390R, E399DCRF02_AG
 48-30363036-30310DQ877947NRTINNRTID67N, T69D, K70R, M184I, K219HA98G, V108I, Y181C, G190AV35T, E36A, T39K, K46M, V60I, V90I, K101R, K122E, D123S, S162A, S163T, T165I, Q174E, D177E, T200A, E203N, Q207K, L210I, D218E, V245Q, K275KQ, K277R, T286A, E291D, I293V, P294T, E297EK, E300EQ, S322T, G335D, R356K, M357K, G359S, A360I, A371V, I375V, K390R, K395RCRF02_AG
 48-30903090-30925DQ877999NRTINNRTIM41L, D67N, T69D, K70R, L74I, M184V, L210W, T215F, K219QA98G, K103N, V108I, Y181CV35T, T39A, K49R, V60I, V90I, K122E, I135V, S162E, E169K, K173T, Q174K, D177E, I178M, T200A, E203D, Q207E, D218E, L228H, V245Q, E248D, D250E, L283I, A288T, E291D, V292I, I293V, P294T, S322T, G335D, M357Q, G359S, A371V, I375V, A376S, K390R, K395RCRF02_AG
Laurent (2006)CK22-7503CM2-75AM279460AZT, DDI, D4T, 3TCEFVD67N, K70R, M184V, T215F, K219EK103N, V108I, K238TV35T, T39L, K64R, D123E, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, R358K, G359S, K366R, T369V, A371V, I375V, K388R, K390R, K395R, E399D, A400T, T403M, E413D, E432DCRF02_AG
Sylla (2008)D673D673_C1DQ991672AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554N, K558RCRF02_AG
  D673_C2DQ991673AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534SCRF02_AG
 A2619A2619_C1EF525657AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
  A2619_C2EF525658AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
Hawkins (2009)P647ZZP647FJ931151D4T, 3TCNVPM184V, T215YV108I, Y181CV35T, K49R, D123E, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, H221Y, V245Q, T253S, T286A, E291D, V292I, I293V, P294T, V317A, S322A, I326IVCRF02_AG
 Q172ZZQ172FJ931190D4T, 3TCNVPM184VV108I, Y181C, G190GAV35T, K49R, D123E, I135V, S162A, E169K, K173T, Q174E, D177E, T200A, Q207E, R211K, H221HY, V245Q, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q771ZZQ771FJ931244AZT, 3TCEFVD67T, K70R, L74LI, M184V, T215F, K219EK103N, V108I, Y181C, G190GAV35T, E36D, T69N, K101KR, D123E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, D218E, L228H, P243S, V245T, K277R, L283I, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q434ZZQ434FJ931266D4T, 3TCNVPM184VA98AG, V108I, Y181CV35I, V60VI, I135V, S162A, K173T, Q174K, D177E, V179I, V189I, T200A, I202V, Q207E, R211K, T215X, V245Q, E248DN, S251H, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q960ZZQ960FJ931289AZT, D4T, 3TCNVPK70R, L74LI, M184V, T215F, K219QK103N, V108I, M230LV35T, E36D, K64KR, T69N, V90I, K122M, S162A, K173T, Q174K, D177E, I178L, Q207E, R211K, L228Q, Q242K, V245Q, K275KR, K281KR, L283I, T286A, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R121ZZR121FJ931330D4T, 3TCNVPM184V, T215YV108I, Y181CT7I, V35T, E36D, V90I, K122E, I135V, S162A, K173T, Q174E, D177E, V179VI, T200A, Q207E, R211K, H221Y, V245Q, K281R, T286A, K287KR, E291D, V292I, I293V, P294T, E297EK, S322T, I326VCRF02_AG
 R23ZZR23FJ931363AZT, 3TCNVPM184VV108I, Y181CV35T, E36D, V90I, I135V, T139TK, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, H221Y, V245K, S251N, K275R, V276I, T286A, E291D, V292I, I293V, S322TCRF02_AG
 R215ZZR215FJ931368AZT, 3TCEFVM41L, D67N, K70R, V75VL, M184V, L210W, T215F, K219EK101E, V108I, Y181C, G190AV35IT, E36D, T39TA, K43Q, V60I, D123E, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, L228H, P243H, V245E, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R468ZZR468FJ931392D4T, 3TCNVPA62AV, V75VI, F77FL, Q151M, M184V, K219QV108I, Y181CK20R, V35T, E36D, T39A, K43E, K49R, K64R, K122E, I135V, S162A, E169EA, K173A, Q174K, N175Y, D177E, T200A, Q207E, H221Y, L228LR, V245Q, E248D, K281R, E291D, I293V, P294T, S322T, I329VCRF02_AG
 R469ZZR469FJ931393D4T, 3TCNVPM41L, D67DG, T69TADN, M184V, T215YK101E, V108I, Y181C, G190AE28R, K32E, V35T, E36D, E44ED, K49R, E53D, V60VI, V90I, L109I, I135V, S162A, K173T, Q174E, D177E, I178IM, T200A, E203ED, Q207EK, H208HY, R211K, W212WR, H221HY, V245K, A272P, K281R, T286A, E291D, V292I, I293V, E297Q, S322T, I326VCRF02_AG
 R364ZZR364FJ931421NRTINVPM41L, M184V, L210LRW, T215YA98AG, V108I, Y181CV35T, T39R, K43E, K122E, D123N, I135L, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211K, H221Y, L228Q, V245Q, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R236ZZR236FJ931431NRTIEFV, NVPM41L, K70R, M184V, K219QA98G, K103N, V108I, Y181C, G190AV35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R474ZZR474FJ931436D4T, 3TCNVPM184V, T215YV108I, Y181CV35T, K49R, V60I, S68G, D123E, I135V, S162D, E169K, K173T, Q174E, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248D, K281KR, T286A, E291ED, V292VI, I293V, P294T, S322T, I326VCRF02_AG
 R439ZZR439FJ931449AZT, 3TCNVPM41L, L74LI, M184V, L210W, T215YK103N, V108IV35T, E44ED, V90I, D123E, I135IT, S162A, K166R, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, V245E, A272P, K277R, K281R, L283I, T286A, E291D, V292I, I293V, I326VCRF02_AG
Burda (2010)06LPH20SC06LPH20SCGQ344969D4T, 3TCNVPF116Y, Q151M, M184VV108I, Y181C, F227LK20R, V35T, E36D, T39L, K49R, S68G, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, E224D, P243H, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, D320X, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403MCRF02_AG
Aghokeng (2011)SK2047-M12SK2047-M12HQ864447AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EK103N, V108IV35T, E36D, T39M, K122E, I135T, S162A, Q174E, D177E, T200A, Q207K, R211A, V245Q, E248DN, A272P, T286A, E291D, V292I, I293V, P294TCRF02_AG
Dagnra (2011)08TG.T304608TG.T3046FR715261D4T, 3TCNVPD67G, K70R, M184V, T215F, K219EV108I, Y181CK20R, V35T, K64H, L109I, K122E, D123N, I135T, S162A, E169Q, K173T, Q174K, N175Y, D177E, T200A, I202V, Q207E, R211K, F214L, H221Y, L228H, V245E, E248D, D250E, L283I, T286A, E291D, V292I, I293V, P294T, S322T, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377I, K390R, A400T, T403MCRF02_AG
 08TG.E501308TG.E5013FR715271D4T, 3TCNVPM184VV108I, Y181CV35T, T69N, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, E224EK, V245Q, E248EK, I257V, R284RG, T286A, E291D, V292I, I293V, P294T, S322T, K331KN, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376T, T377L, S379C, V381I, K390R, E396D, E432DCRF02_AG
Fokam (2011)CIRCB-10124CIRCB-10124JQ796164AZT, 3TCNVPM184VA98G, K103N, V108IV35T, T39A, V90I, K122KE, D123T, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, E248D, K275Q, V276I, T286A, E291D, V292VI, I293V, P294T, E300K, S322TCRF02_AG

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