<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V108I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 31
Patients 127
Isolates 129
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patSCHE02_SCHE715AJ578156D4T, DDINVPM41L, T215YV108I, Y181CP4S, V35T, E36D, V90I, K104R, K122E, I135V, S162A, E169G, K173A, Q174K, D177E, I178M, V189I, T200A, Q207E, R211K, H221Y, F227ICRF02_AG
 MB_patROU00_ROUX701AJ577987AZT, Unknown, DDI, 3TCUnknown, NVPM41L, D67N, K70R, M184V, T215Y, K219EA98G, V108I, Y181CV60I, L109I, I135V, S162A, K173T, Q174E, D177E, T200A, I202V, Q207E, V245A, E248K, D250ECRF02_AG
Non-B Workgroup (2005)PL5171397428 3TC, D4TNVP, EFVM184VK103KN, V108I, V179VE, Y181CK20KR, V35T, A98S, D123E, I135T, S162A, E169D, K173R, Q174A, D177E, T200A, Q207E, R211K, F214L, L228R, V245Q, A272P, T286A, E291D, V292I, I293V, E297A, I329LCRF02_AG
 PL55432107397 D4T, DDI, TDF, 3TCNVP, EFVK65R, M184VK103N, V108I, F227FL, M230LV35T, E36D, K49R, S68SG, K122N, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, H221Y, V245E, K275R, V276I, L283I, T286A, E291D, I293V, P294T, V317A, S322T, I326VCRF02_AG
Toni (2005)IC03nvp28IC03nvp28DQ056394NoneNVP V108IV35T, S162A, K173T, Q174K, D177E, T200A, Q207E, Q222QLCRF02_AG
Baxter (2006)48-12261226-30417DQ877758NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215Y, K219EK103S, V108I, G190AP4Q, K20R, V35T, T39A, E44D, V60I, V118I, K122E, D123N, I135V, S162A, K173V, Q174K, D177E, I178M, Q197L, T200A, E203V, Q207E, K223Q, L228H, P243T, V245Q, T286A, I293V, P294T, S322A, G335D, M357K, R358K, G359S, A371V, I375V, A376T, T377M, T386A, K390R, E399D, A400TCRF02_AG
 48-30363036-30310DQ877947NRTINNRTID67N, T69D, K70R, M184I, K219HA98G, V108I, Y181C, G190AV35T, E36A, T39K, K46M, V60I, V90I, K101R, K122E, D123S, S162A, S163T, T165I, Q174E, D177E, T200A, E203N, Q207K, L210I, D218E, V245Q, K275KQ, K277R, T286A, E291D, I293V, P294T, E297EK, E300EQ, S322T, G335D, R356K, M357K, G359S, A360I, A371V, I375V, K390R, K395RCRF02_AG
 48-30903090-30925DQ877999NRTINNRTIM41L, D67N, T69D, K70R, L74I, M184V, L210W, T215F, K219QA98G, K103N, V108I, Y181CV35T, T39A, K49R, V60I, V90I, K122E, I135V, S162E, E169K, K173T, Q174K, D177E, I178M, T200A, E203D, Q207E, D218E, L228H, V245Q, E248D, D250E, L283I, A288T, E291D, V292I, I293V, P294T, S322T, G335D, M357Q, G359S, A371V, I375V, A376S, K390R, K395RCRF02_AG
Laurent (2006)CK22-7503CM2-75AM279460AZT, DDI, D4T, 3TCEFVD67N, K70R, M184V, T215F, K219EK103N, V108I, K238TV35T, T39L, K64R, D123E, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, R358K, G359S, K366R, T369V, A371V, I375V, K388R, K390R, K395R, E399D, A400T, T403M, E413D, E432DCRF02_AG
Sylla (2008)D673D673_C1DQ991672AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554N, K558RCRF02_AG
  D673_C2DQ991673AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534SCRF02_AG
 A2619A2619_C1EF525657AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
  A2619_C2EF525658AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EA98G, V108I, V179E, Y181CV35T, E36D, V90I, L109I, D121Y, K122E, I135V, T139S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E399D, T403M, E432D, V435LCRF02_AG
Hawkins (2009)P647ZZP647FJ931151D4T, 3TCNVPM184V, T215YV108I, Y181CV35T, K49R, D123E, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, H221Y, V245Q, T253S, T286A, E291D, V292I, I293V, P294T, V317A, S322A, I326IVCRF02_AG
 Q172ZZQ172FJ931190D4T, 3TCNVPM184VV108I, Y181C, G190GAV35T, K49R, D123E, I135V, S162A, E169K, K173T, Q174E, D177E, T200A, Q207E, R211K, H221HY, V245Q, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q771ZZQ771FJ931244AZT, 3TCEFVD67T, K70R, L74LI, M184V, T215F, K219EK103N, V108I, Y181C, G190GAV35T, E36D, T69N, K101KR, D123E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, D218E, L228H, P243S, V245T, K277R, L283I, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q434ZZQ434FJ931266D4T, 3TCNVPM184VA98AG, V108I, Y181CV35I, V60VI, I135V, S162A, K173T, Q174K, D177E, V179I, V189I, T200A, I202V, Q207E, R211K, T215X, V245Q, E248DN, S251H, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q960ZZQ960FJ931289AZT, D4T, 3TCNVPK70R, L74LI, M184V, T215F, K219QK103N, V108I, M230LV35T, E36D, K64KR, T69N, V90I, K122M, S162A, K173T, Q174K, D177E, I178L, Q207E, R211K, L228Q, Q242K, V245Q, K275KR, K281KR, L283I, T286A, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R121ZZR121FJ931330D4T, 3TCNVPM184V, T215YV108I, Y181CT7I, V35T, E36D, V90I, K122E, I135V, S162A, K173T, Q174E, D177E, V179VI, T200A, Q207E, R211K, H221Y, V245Q, K281R, T286A, K287KR, E291D, V292I, I293V, P294T, E297EK, S322T, I326VCRF02_AG
 R150ZZR150FJ931346D4T, 3TCNVPF116Y, Q151M, M184VV108I, Y181CK20K*, V35T, K102R, K104KQ, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, H221Y, P243Q, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297K, I329VCRF02_AG
 R23ZZR23FJ931363AZT, 3TCNVPM184VV108I, Y181CV35T, E36D, V90I, I135V, T139TK, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, H221Y, V245K, S251N, K275R, V276I, T286A, E291D, V292I, I293V, S322TCRF02_AG
 R215ZZR215FJ931368AZT, 3TCEFVM41L, D67N, K70R, V75VL, M184V, L210W, T215F, K219EK101E, V108I, Y181C, G190AV35IT, E36D, T39TA, K43Q, V60I, D123E, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, L228H, P243H, V245E, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R468ZZR468FJ931392D4T, 3TCNVPA62AV, V75VI, F77FL, Q151M, M184V, K219QV108I, Y181CK20R, V35T, E36D, T39A, K43E, K49R, K64R, K122E, I135V, S162A, E169EA, K173A, Q174K, N175Y, D177E, T200A, Q207E, H221Y, L228LR, V245Q, E248D, K281R, E291D, I293V, P294T, S322T, I329VCRF02_AG
 R469ZZR469FJ931393D4T, 3TCNVPM41L, D67DG, T69TADN, M184V, T215YK101E, V108I, Y181C, G190AE28R, K32E, V35T, E36D, E44ED, K49R, E53D, V60VI, V90I, L109I, I135V, S162A, K173T, Q174E, D177E, I178IM, T200A, E203ED, Q207EK, H208HY, R211K, W212WR, H221HY, V245K, A272P, K281R, T286A, E291D, V292I, I293V, E297Q, S322T, I326VCRF02_AG
 R364ZZR364FJ931421NRTINVPM41L, M184V, L210LRW, T215YA98AG, V108I, Y181CV35T, T39R, K43E, K122E, D123N, I135L, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211K, H221Y, L228Q, V245Q, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R236ZZR236FJ931431NRTIEFV, NVPM41L, K70R, M184V, K219QA98G, K103N, V108I, Y181C, G190AV35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R474ZZR474FJ931436D4T, 3TCNVPM184V, T215YV108I, Y181CV35T, K49R, V60I, S68G, D123E, I135V, S162D, E169K, K173T, Q174E, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248D, K281KR, T286A, E291ED, V292VI, I293V, P294T, S322T, I326VCRF02_AG
 R439ZZR439FJ931449AZT, 3TCNVPM41L, L74LI, M184V, L210W, T215YK103N, V108IV35T, E44ED, V90I, D123E, I135IT, S162A, K166R, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, V245E, A272P, K277R, K281R, L283I, T286A, E291D, V292I, I293V, I326VCRF02_AG
Burda (2010)06LPH20SC06LPH20SCGQ344969D4T, 3TCNVPF116Y, Q151M, M184VV108I, Y181C, F227LK20R, V35T, E36D, T39L, K49R, S68G, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, E224D, P243H, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, D320DE, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403MCRF02_AG
Aghokeng (2011)SK2047-M12SK2047-M12HQ864447AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EK103N, V108IV35T, E36D, T39M, K122E, I135T, S162A, Q174E, D177E, T200A, Q207K, R211A, V245Q, E248DN, A272P, T286A, E291D, V292I, I293V, P294TCRF02_AG
Charpentier (2011)CR-41CR-41FJ688247AZT, 3TCNNRTIA62V, K70KN, V75I, F116Y, Q151M, M184V, T215SK103N, V108IV35T, K43KNRS, I47IL, K49R, S68G, T69TI, K122E, D123S, I135L, S162D, K173I, Q174K, D177E, Q197K, T200A, I202IV, R211K, V245Q, A272P, K281KR, V292I, I293V, S322A, I326VCRF02_AG
 CR-38CR-38FJ688244AZT, 3TCNNRTID67N, K70R, V75A, M184V, T215Y, K219QK103N, V108I, K238TV35T, E36D, K46Q, K49R, K73M, K122E, D123S, I135V, S162A, T165I, K173T, Q174K, N175Y, D177E, T200A, K201KR, Q207E, R211K, F214FL, H221Y, L228LH, V245Q, K275R, L283I, T286A, E291D, V292I, I293V, P294T, E297EK, E312A, S322ACRF02_AG
Dagnra (2011)08TG.T304608TG.T3046FR715261D4T, 3TCNVPD67G, K70R, M184V, T215F, K219EV108I, Y181CK20R, V35T, K64H, L109I, K122E, D123N, I135T, S162A, E169Q, K173T, Q174K, N175Y, D177E, T200A, I202V, Q207E, R211K, F214L, H221Y, L228H, V245E, E248D, D250E, L283I, T286A, E291D, V292I, I293V, P294T, S322T, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377I, K390R, A400T, T403MCRF02_AG
 08TG.E501308TG.E5013FR715271D4T, 3TCNVPM184VV108I, Y181CV35T, T69N, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, E224EK, V245Q, E248EK, I257V, R284RG, T286A, E291D, V292I, I293V, P294T, S322T, K331KN, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376T, T377L, S379C, V381I, K390R, E396D, E432DCRF02_AG
Fokam (2011)CIRCB-10124CIRCB-10124JQ796164AZT, 3TCNVPM184VA98G, K103N, V108IV35T, T39A, V90I, K122KE, D123T, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, E248D, K275Q, V276I, T286A, E291D, V292VI, I293V, P294T, E300K, S322TCRF02_AG
Sigaloff (2011)HIV103588HIV103588JN132352AZT, 3TCEFVM184VK103N, V108IP4S, V35T, E36D, E53D, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, R211K, F214L, K223T, V245E, D250ECRF02_AG
Fourati (2012)90301169030116JQ396041NRTINNRTIM184V, L210LW, T215SYK103N, V108IK20R, V21I, V35LR, E36ED, T39A, S68G, L109I, I135V, S162T, K173T, Q174K, D177E, I178M, V189I, T200A, E203K, Q207E, R211KCRF02_AG
Hamers (2012)CP076305197CP076305197 TDF, FTCNVPK65R, Y115F, M184VV108I, Y181CP4T, K11S, V35T, E40D, V90VI, D121Y, K122E, D123G, I135T, S162A, K173T, Q174KR, T200A, I202V, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P321S, D324E, I329VCRF02_AG
Aghokeng (2013)HJ3115HJ3115JX983015NRTINNRTIM184VV108I, Y181CE6D, V35T, E36D, T39A, K122E, D123GS, I135V, T139TK, S162A, K173T, D177E, T200A, Q207E, H221Y, V245Q, K277R, T286A, V292I, I293V, S322T, G335E, P345Q, R356K, M357K, G359S, A371V, I375V, K390R, A400AT, T403MCRF02_AG
 HJ3188HJ3188JX982995NRTINNRTIM184V, T215FK103N, V108I, M230L, L234IV35T, E36D, R78RK, K122E, D123S, I135M, S162A, K173T, Q174K, D177E, I178L, V189VI, T200A, Q207E, R211RK, H221Y, L228LH, V245EK, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357K, G359S, A360T, I375V, T377L, K390R, K395RCRF02_AG
 HJ3168HJ3168JX982991NRTINNRTIM184VK103N, V108IV35T, V60I, D121H, K122E, I135V, T139TK, A158AS, S162ST, K173N, Q174K, D177E, T200A, Q207E, R211K, H221HY, P243T, V245H, T286A, E291D, I293V, P294A, S322T, I326V, R356K, M357K, G359S, A371V, I375V, T377V, K390R, E399D, T403M, E413DCRF02_AG
 HJ3059HJ3059JX983018NRTINNRTIK70R, M184V, T215F, K219QK103N, V108I, M230LV35T, T69N, K122E, D123N, I135V, S162A, K173T, Q174E, D177E, T200E, E203Q, Q207E, R211K, L228R, V245T, A272P, K281R, L283I, T286A, A288T, I293V, P294T, S322A, I326IV, G335D, R356K, M357K, G359S, A371V, I375V, T377L, S379G, K390R, T403MCRF02_AG
Etiebet (2013)7020307NG.SN080HQ843563TDF, FTCEFVK65R, K70H, K219RK101E, V108I, Y181C, G190A, P225PHV35T, T39R, E40Q, K43E, K46Q, K49R, S68G, E138G, A158S, S162A, K173A, Q174E, D177E, I178M, T200A, E204K, Q207E, R211K, F214L, L228RCRF02_AG
Kebe (2013)SNA3-214SNA3-214HM002516NRTINNRTIA62V, K65R, V75I, F116Y, Q151M, M184V, K219EV108I, Y181CI31L, V35T, E36D, V60I, K64R, S68R, N81NT, V118I, K122E, R143R*, S162A, K173T, Q174K, D177E, T200A, Q207K, R211S, F214L, V245QCRF02_AG
 SNA3-139SNA3-139JN193500NRTINVPM184VA98AG, K101E, V108I, G190AV35T, E36D, V60I, K102Q, V106I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207ECRF02_AG
Nii-Trebi (2013)KF128KF128AB751483AZT, 3TCNVPD67N, T69DN, K70R, M184V, T215F, K219QV108I, Y181CK20R, K32E, V35T, E36A, T39K, K43A, V60I, L109I, D121H, K122E, I135R, T139R, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, L228H, V245QCRF02_AG
 775775AB751454D4T, 3TCEFVM184VK101E, V108I, G190SK13KN, V35T, E36D, K49R, V106VI, K122P, I135V, S162A, T165I, E169D, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, V245QCRF02_AG
Pircher (2013)B1137B1137JX110237D4T, 3TC, AZTNVPM41ML, M184V, L210W, T215YA98G, K103N, V108IK20R, V35T, E36D, T39LS, K43KE, V60VI, L109LI, D123E, I135T, S162AT, K173T, Q174K, N175NY, D177E, G196E, T200A, Q207E, R211K, V245QCRF02_AG
 B1125B1125JX110225D4T, 3TC, AZTNVPL74I, M184V, T215FY, K219KNA98G, K101E, V108I, M230LK22R, V35T, T39L, S68G, K104R, K122E, D123S, E138A, S162A, Q174K, T200A, E203D, Q207D, H221Y, V245QCRF02_AG
 B1151B1151JX110247D4T, 3TC, AZTNVPD67DN, K70R, M184V, K219KQV108I, Y188W, F227LV35T, T39A, E40D, V60VI, D121H, K122E, I135T, T139KR, K173T, Q174K, D177E, T200A, Q207E, R211RK, H221Y, V245QCRF02_AG
Rawizza (2013)PJ9681PJ9681KF241511NRTINNRTIA62V, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219EK103N, V108I, K238TP14A, D17DE, V35T, E36D, E40K, K43Q, K46Q, K49R, T58N, S68G, K122E, D123N, I135IV, S162T, K173T, Q174K, D177E, I178IM, T200A, E203EK, Q207E, R211K, I244IT, V245E, A272P, Q278N, L283I, E291D, V292I, I293V, P294A, S322T, D324ECRF02_AG
Theys (2013)33253325KC219252NRTI, TDFNNRTIK65R, M184VK103N, V108I, F227FL, M230LK49R, S68SG, K122N, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, H221YCRF02_AG
 2788827888KC220538NRTI, TDFNNRTIM41L, D67N, V75T, M184V, T215Y, K219EV108I, Y181CK49R, I135V, S162A, K166E, E169K, K173T, Q174N, D177E, I178M, T200A, Q207E, R211K, F214FL, H221YCRF02_AG
 2618226182KC220408NRTI, TDFNNRTIM41L, D67N, V75T, M184V, T215Y, K219EV108I, Y181CK49R, I135V, S162A, K166E, E169K, K173T, Q174N, D177E, I178M, T200A, Q207E, R211K, H221YCRF02_AG
 5503555035KC221678NRTI, TDFNNRTIF77FLK103N, V108I, P225H, F227CV60I, V90I, D123E, I135V, E138Q, S162A, K173S, Q174K, D177E, V179I, G196E, T200A, Q207A, H221YCRF02_AG
 4625246252KC221354NRTI, TDFNNRTIM41L, D67G, L74I, M184V, L210W, T215Y, K219NA98G, V108IE44D, S68G, L109I, V118I, D123E, S162A, K173T, Q174E, D177E, T200A, E203K, Q207E, H208Y, R211K, D218E, K223QCRF02_AG
 2276922769KC220150NRTI, TDFNNRTI V108IE40D, V90VI, K122P, D123E, S162A, K173T, Q174K, P176PST, D177E, V189VI, T200A, Q207E, R211RK, D237NCRF02_AG
Theys (2013)162310162310 AZT, 3TCEFVM184VK103N, V108II5V, K20R, V35T, K104R, K122E, D123G, I135V, S162DN, R172RK, K173Q, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, I293V, S322A, I326VCRF02_AG
Thiam (2013)3105-HALD3105-HALDJN673614NRTINNRTIM184VK103N, V108I, K238KITK20R, V35T, T39M, V60I, V90I, K122P, I135V, T139R, S162A, K173T, Q174K, D177EK, G196E, T200A, Q207E, R211K, D237DN, P243PCRS, V245Q, L246LV, E248DGNS, D250DGNS, S251SI, T253TS, K281R, T286A, E291D, V292I, I293V, P294T, E297R, S322T, I326VCRF02_AG
 418-HALD418-HALDJN673621NRTINNRTIL74V, M184VV108I, Y181CV35I, V90I, K122E, D123N, I135L, S162A, K173T, Q174K, D177E, T200A, Q207E, H221Y, I244IV, V245K, D250E, S251I, K275KQ, K281KR, T286A, A288T, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 2187HALD2187HALDJX187615NRTINNRTIM41L, D67N, K70R, M184V, T215Y, K219EA98G, V108I, Y181CV35T, E36D, E44D, V60I, D123E, S162D, K173T, Q174K, D177E, I178M, T200A, Q207G, R211K, H221Y, L228H, V245Q, P247ACRF02_AG
 3210-HALD3210-HALDJN673615NRTINNRTID67G, K70R, M184V, T215F, K219EA98G, K103N, V108IV35T, E36D, T39L, K49R, S68G, K101KR, K122E, I135V, S162A, E169K, K173T, Q174E, D177E, I178M, T200A, E203K, Q207E, R211K, K223E, P243S, V245Q, E248D, T286A, E291D, I293IV, P294T, L295LM, S322T, I326V, I329IVCRF02_AG
 2841-HALD2841-HALDJN673708NRTINNRTIM41L, L74I, M184V, L210W, T215YA98G, K103N, V108IE28K, K32I, V35T, T39K, K43E, V60I, K101A, V118I, K122E, D123S, K173T, Q174K, D177E, T200A, E203K, Q207D, R211K, K223E, L228R, V245Q, T286A, E291D, I293V, P294TCRF02_AG
Aghokeng (2014)TG-3-132TG-3-132KC350312NRTINNRTIM184V, N348IK103N, V108I, Y181CV35T, E36A, T39K, K43E, K49R, D121H, I135IV, I142V, I159IL, S162D, K173S, Q174K, I178L, V179I, T200A, Q207E, R211K, H221Y, V245Q, A272P, T286A, E291D, V292I, I293V, S322A, I326V, G335D, M357R, G359S, K366R, T369V, A371V, I375V, A376I, T403M, W410C, E413D, E432DCRF02_AG
 TG-1-192TG-1-192KC350052NRTINNRTIM184VV108I, G190AE36D, D123E, I135L, S162A, K173T, Q174K, D177E, I178L, T200A, E203D, Q207E, R211K, V245Q, A272P, T286A, V292I, I293V, P294E, S322T, G335D, R356K, M357K, G359S, A371V, I375V, A376S, T377V, K390R, K395R, A400T, E432D, I434LCRF02_AG
 TG-4-642TG-4-642KC350295NRTINNRTIK70R, M184V, K219KQ, N348ITV108I, Y181CV35K, E36D, K49R, V60I, K64KR, K102Q, K122E, D123N, I135V, T139I, S162A, E169D, K173T, Q174K, D177E, T200A, R211K, F214L, H221Y, V245Q, D250DG, K281R, T286A, E291D, I293V, P294T, S322T, I326V, A327V, G335D, F346L, R356K, M357R, G359S, A371L, I375V, A376S, T377V, K390R, A400TCRF02_AG
 TG-3-126TG-3-126KC350309NRTINNRTID67G, K70R, M184V, T215F, K219EV108I, Y181CK20R, V35T, T39A, K64H, L109I, K122E, D123N, I135T, S162A, E169Q, K173T, Q174K, N175Y, D177E, G196GE, T200A, K201R, I202V, Q207E, R211K, F214L, D218E, L228H, V245E, D250E, L283I, T286A, E291D, V292I, I293V, P294T, S322T, D324E, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377I, K390R, A400T, T403M, F416FL, E432DCRF02_AG
 TG-1-487TG-1-487KC350285NRTINNRTIK70R, M184V, K219Q, N348IV106A, V108I, F227LV35T, E36D, S105I, D121H, K122E, I135V, S162A, Q174E, D177E, T200A, E203D, Q207E, R211K, L228R, P243T, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403M, E432DCRF02_AG
 CI-1-30-CI-1-30-KC350029NRTINNRTIV75I, M184VV108I, Y181CV35T, K49R, V60I, D123E, I132V, I135V, S162A, K173T, Q174K, D177E, D192Y, T200A, Q207E, R211KCRF02_AG
 TG-2-552TG-2-552KC349995NRTINNRTIM184V, N348IK103N, V108IV35T, E36D, K122P, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, P243T, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376S, K390R, E396D, T403M, E432D, V435ICRF02_AG
 TG-2-417TG-2-417KC350078NRTINNRTIM184IVV108I, V179E, Y181CK20R, K22R, V35T, T39A, E40D, K122P, D123E, I135V, S162A, K173T, Q174K, D177E, Q197QL, T200A, Q207E, F214FL, V245Q, A272P, K277Q, Q278K, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, T377L, K390R, A400T, T403M, E432DCRF02_AG
 TG-1-191TG-1-191KC350082NRTINNRTIA62V, Q151M, M184IV108I, Y181CI2V, V35T, T39L, V90I, K122E, D123N, I135R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, V245Q, A272P, K275Q, K277R, Q278N, E291D, V292I, P294T, S322T, I326V, G335D, P345L, R356K, M357R, G359FCRF02_AG
 TG-3-587TG-3-587KC350291NRTINNRTIA62V, F116FY, Q151M, M184V, K219KEK103N, V108I, Y318FM16V, K20R, V35T, E36D, S68G, K102Q, K122P, S162A, K173T, Q174K, D177E, I178L, T200A, Q207E, F214FL, V245Q, A272P, K275Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T377I, S379C, K390R, K395R, E399D, T403M, E413DCRF02_AG
 TG-1-383TG-1-383KC350077NRTINNRTIM41ML, D67DN, K70R, M184V, T215F, K219EQA98G, K103KN, V108I, Y181C, M230MLV35T, E36D, K49R, V106VI, K122E, D123N, I135IV, S162A, E169A, K173T, Q174K, D177E, T200A, Q207E, R211K, H221Y, L228R, V245Q, L283LI, T286A, E291D, V292I, I293V, P294T, S322T, I326V, Q334QP, G335D, R356K, M357R, G359S, V365I, A371V, I375V, A376G, K390R, T403M, Y405H, E432DCRF02_AG
Jenabian (2015)DR39DR39KF735843NRTINNRTIM41L, M184V, T215FYA98G, K103N, V108IK20R, V35T, T39K, K43E, V60I, D121Y, K122E, I135T, S162A, K173A, Q174N, D177E, T200A, E203K, Q207E, H208HY, K223E, L228R, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E312D, S322A, I326VCRF02_AG
 DR11DR11KF735822NRTINNRTIM41L, L74V, M184V, L210W, T215FK103N, V108I, Y181C, G190AV35T, T39A, E44D, V118I, K122E, D123N, S162D, K173T, Q174K, D177E, I178M, G196E, T200A, E203K, Q207D, R211K, K223KE, L228H, V245Q, T286TA, E291D, V292VI, I293V, P294AT, E297K, A304E, S322A, I326V, G335DCRF02_AG
Konou (2015)H1450H1450KT316174NRTINNRTIM41L, D67N, M184I, L210W, T215Y, K219NA98G, K101KE, V108I, Y181C, G190AV35T, T39L, E44D, V90I, V118I, D123E, I135T, S162A, T165I, K173A, Q174K, D177E, I178M, G196GE, T200A, E203D, Q207E, R211K, D218DE, H221YCRF02_AG
 H576H576KT316173NRTINNRTIM184VK103N, V108IV35T, E36D, V60I, V90VI, K122P, I135V, S162A, Q174E, D177E, I180V, T200A, Q207E, R211K, V245QCRF02_AG
 H1507H1507KT316163NRTINNRTIK70R, V75L, M184VV108I, V179VE, Y181CK20R, K32Q, V35T, T39L, V60I, T69N, I135R, T139I, S162A, K173T, Q174K, N175NY, D177E, T200A, E203X, Q207E, F214L, V245K, D250ECRF02_AG
 H534H534KT316160NRTINNRTIM41L, D67N, L74V, M184V, T215YV108I, Y181CV35T, K43N, E44D, K49R, V60I, K64R, L109I, K122E, I135V, T139K, S162A, K173R, Q174K, N175Y, D177E, T200A, Q207E, R211K, V245K, D250ECRF02_AG
 H685H685KT316135NRTINNRTID67N, M184V, L210W, T215YV108I, Y181CL34I, V35T, T39D, E44D, K101Q, V111I, I135T, S162A, K173R, Q174D, D177E, T200A, E203D, Q207E, R211RK, K219X, H221Y, V245X, L246ICRF02_AG
 H547H547KT316131NRTINNRTIM41L, D67N, T69D, K70R, M184V, T215F, K219QA98G, V108I, Y181CK20R, L34I, V35T, T39E, K122P, S162A, K173T, Q174A, D177E, T200A, Q207E, F214L, H221Y, V245X, L246MCRF02_AG
 H524H524KT316127NRTINNRTID67N, T69D, K70R, M184V, T215F, K219QA98G, V108I, Y181CK20R, V35T, T39K, K43A, K49R, V60I, I135V, S162E, E169D, K173T, Q174K, D177E, I178M, G196E, T200A, E203K, Q207E, D218E, P243T, V245Q, D250ECRF02_AG
 H476H476KT316121NRTINNRTID67G, K70R, M184V, T215F, K219EV108I, Y181CP1PS, G18GA, V35T, E36D, V60I, S68G, D123E, I135V, S162A, T165V, K173T, Q174K, D177E, T200A, Q207E, H221Y, V245QCRF02_AG
 H1391H1391KT316101NRTINNRTIM41L, M184V, L210W, T215YK103N, V108IV35T, T39M, E44D, V60I, A98S, V118I, I135T, S162A, K173T, Q174K, N175Y, D177E, T200A, K201R, E203K, Q207E, R211K, K223E, L228R, P243T, V245KCRF02_AG
 H1549H1549KT316089NRTINNRTIA62V, V75I, F77L, F116Y, Q151M, M184VK103N, V108IV35T, T39A, S68G, T69TI, E79EK, G93GE, K122P, R125RK, I135V, E138Q, S162A, T165TI, K173T, Q174N, D177E, I178M, T200X, Q207A, R211K, F214L, K219KT, V245Q, E248D, D250ECRF02_AG
 H1521H1521KT316087NRTINNRTIM41L, L74I, M184V, L210W, T215FA98G, K103N, V108IK20R, V35K, T39A, K43E, E44A, V60I, S68G, V118I, I135L, S162A, K173A, Q174K, N175Y, D177E, I178M, T200A, K201R, Q207E, R211K, V245QCRF02_AG
 H1499H1499KT316085NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215Y, K219EK103N, V108I, V179E, Y181CE6D, V35T, T39A, E44D, V60I, A98S, V118I, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248DCRF02_AG
 H460H460KT316071NRTINNRTID67N, K70R, M184V, T215F, K219QV108I, Y181CE6K, K20KR, E29EK, V35T, T39A, E40D, T69X, K122E, D123E, I135V, S162X, K173T, Q174K, D177E, G196E, T200A, Q207A, R211K, F214L, H221Y, L228H, Q242H, V245QCRF02_AG
 H421H421KT316062NRTINNRTID67N, K70R, M184V, T215TI, K219QA98G, V108I, Y181CA33AG, V35T, T39A, E40D, K49R, V60I, T69N, K122P, I135V, S162A, E169D, Q174E, D177E, I178X, G196GE, T200A, E204K, Q207E, F214L, D218E, L228H, V245Q, D250ECRF02_AG
 H379H379KT316061NRTINNRTIM41ML, D67N, K70R, M184V, T215F, K219EA98G, K103N, V108IV35T, V60VI, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, R211K, V245KCRF02_AG
 H325H325KT316056NRTINNRTIM184VK101E, V108I, Y181CV35T, T39A, D123E, I135V, T139K, S162A, K173T, Q174K, D177E, I178L, T200A, K201KR, Q207X, R211RK, H221Y, V245QCRF02_AG
 H758H758KT316055NRTINNRTIT69D_GGI, M184V, K219RV108I, Y181CK11T, K30T, I31L, V35T, E36K, T39M, D67X, S68E, V90I, K101KQ, D121C, K122E, D123S, I135T, S162A, E169A, Q174E, D177E, T200A, I202V, Q207E, V245K, D250ECRF02_AG
 H985H985KT316054NRTINNRTIM184V, T215FK103N, V108I, M230LV35M, T39A, D123E, I135T, S162A, K173T, Q174K, D177K, T200A, Q207E, R211K, L228N, W229G, K238R, V245K, E248DCRF02_AG
 H906H906KT316049NRTINNRTIM41L, M184V, L210W, T215YA98G, V108I, Y181CV35T, E36D, K43Q, K49R, D121H, K122E, I135T, S162A, F171Y, K173A, Q174K, D177G, I178L, V179I, T200A, E203K, Q207E, R211K, H221Y, L228H, V245Q, D250ECRF02_AG
 H924H924KT316046NRTINNRTIM41L, M184V, T215YV108I, Y181CV35L, E44D, S68G, I135V, S162A, K173T, Q174K, D177E, I178M, V179I, T200A, E203K, Q207E, R211K, H221Y, V241I, P243H, V245ECRF02_AG
 H854H854KT316038NRTINNRTID67N, K70R, M184V, T215I, K219EK103N, V108I, Y181YC, K238TE28Q, V35T, K43KR, V60I, V90I, D123E, I135T, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, L228H, V245KCRF02_AG
 H870H870KT316028NRTINNRTIA62V, T69D, K70Q, V75T, Q151M, M184VV108I, Y181C, G190A, F227LI31L, V35K, E36D, T39A, K101T, L109I, D123E, I142V, S162A, K173T, Q174K, D177E, T200A, Q207A, F214L, H221YCRF02_AG
 H363H363KT316019NRTINNRTIM41L, M184V, T215YV108I, Y181CT7A, V35T, T39M, V60I, S68G, V90I, I94L, T107S, L109I, K122P, I135V, S162A, K173T, Q174X, D177E, I178L, T200A, Q207E, R211RK, H221Y, V241I, V245QCRF02_AG
 H431H431KT316010NRTINNRTIM41L, L74LI, M184V, L210W, T215YV108I, Y181CM16T, K20R, V35T, T39A, K43KE, E44ED, V118I, K122P, I135T, S162A, K173T, Q174K, D177E, T200A, E203D, R211K, H221Y, L228R, K238KR, V245E, E248DCRF02_AG
 H314H314KT316007NRTINNRTID67N, K70R, M184V, T215F, K219QK103N, V108IK20R, V35T, V60I, T69N, V90I, K102H, D123E, I135T, S162A, Q174E, D177E, T200A, Q207N, R211K, V245QCRF02_AG
 H802H802KT316003NRTINNRTIM41L, D67N, M184V, L210W, T215YA98G, K101E, V108I, G190AK20R, V35T, T39M, K43E, E44D, V118I, K122P, I135K, S162A, K173T, Q174K, D177E, T200A, E203K, Q207D, R211K, V245KCRF02_AG
Lam (2016)2103200321032003KR867958AZT, 3TCNVPM41ML, D67N, K70R, V75I, M184V, T215TI, K219EA98AG, K101EQ, V108I, Y181CK20R, V35T, E36D, T39A, A62T, T69TN, R83K, V90I, I135V, S162A, K173AT, Q174K, N175NY, D177E, T200A, Q207E, V245Q, V276VI, Q278N, T286A, E291D, V292I, I293IV, P294T, S322T, I326V, G335DCRF02_AG
 2103100121031001KR867979TDF, FTCEFVD67G, T69D, K70R, M184V, T215TI, K219EK103N, V108I, Y181CK20KR, V35T, E36D, S48T, V60I, D123E, I135T, S162A, K173T, Q174A, D177E, T200E, E203K, Q207E, L228HR, V245Q, A272P, K275R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
 2103100821031008KR868148AZT, 3TCNVPM184V, K219KHNQV108I, Y181CK20R, V35T, T39R, K43E, V60I, D123E, I135V, I142V, Q174E, D177E, I195IV, T200A, E203K, Q207E, L228R, V245Q, T286A, E291D, V292I, I293V, P294T, E297EK, S322AT, I326V, G335DCRF02_AG
Chaplin (2017)NJIH0350NJIH0350MF622901NRTINNRTIM184V, K219QV108I, Y181CV35T, T39A, E40A, K43E, D123E, I135V, A158T, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207E, R211K, L228R, V245Q, S251NCRF02_AG
 NJIH0314NJIH0314MF622865NRTINNRTIM184V, L210W, T215Y, K219KNK101E, V108I, V179E, G190A, M230LE28A, V35T, T39A, V111I, K122E, I135T, S162A, M164MI, K173T, Q174R, D177E, I178M, G196E, T200A, E203K, Q207E, R211K, H221HY, V245QCRF02_AG
 NJIH0306NJIH0306MF622857NRTINNRTIM41L, L74I, M184V, L210W, T215YA98G, K103N, V108I, P225HK20R, V35T, E44D, S68SG, L109I, D121H, K122E, I135IM, S162A, Q174E, D177X, T200A, Q207E, R211K, V245Q, S251NCRF02_AG
 NJIH0296NJIH0296MF622847NRTINNRTIM184VK103N, V108IE28EK, V35K, E36D, K101KQ, K122E, I135T, S162A, K173I, Q174K, D177E, T200A, Q207E, R211KCRF02_AG
 NJIH0295NJIH0295MF622846NRTINNRTIM184VK103N, V108IE28EK, V35K, E36D, K101KQ, K102KR, K122E, I135T, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245E, D250N, T286A, E291D, V292I, I293V, S322A, G335DCRF02_AG
 NJIH0293NJIH0293MF622844NRTINNRTIM184VK103N, V108IV35T, T39A, E40D, D123E, I135T, S162A, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, E248DCRF02_AG
 NJIH0282NJIH0282MF622833NRTINNRTIM184VA98AG, K103N, V108IV35T, E36D, K49R, K122KT, D123X, I135V, S162A, E169Q, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, D250ECRF02_AG
 NJIH0281NJIH0281MF622832NRTINNRTIM184VK103N, V108IV35T, E36D, K49R, D123E, I135V, S162A, E169K, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
 NJIH0274NJIH0274MF622825NRTINNRTIK70KR, M184V, T215YV108I, Y181CV35T, K49KR, T69N, A98S, K101KQ, K122E, D123X, I135T, K173A, Q174K, D177E, T200A, Q207D, R211K, L228RCRF02_AG
 NJIH0273NJIH0273MF622824NRTINNRTI V108I, Y181CV35T, K49X, A98S, K122E, D123N, I135T, K173A, Q174K, D177E, T200A, Q207D, R211K, L228R, V245H, E248D, D250E, A272T, T286A, E291D, V292I, I293V, P294Q, E312Q, D324E, I329V, Q334L, G335DCRF02_AG
 NJIH0254NJIH0254MF622805NRTINNRTIM41L, M184V, L210W, T215Y, K219NA98G, K103N, V108I, M230LP4S, K20R, V35T, E44D, L109I, V111I, D123E, S162A, K173T, Q174E, D177E, G196GE, I202IV, E203EK, Q207E, H208HY, K223KQ, L228X, V245QCRF02_AG
 NJIH0186NJIH0186MF622737NRTINNRTID67DN, K70R, M184V, T215I, K219EV108I, Y181CV35T, E36D, V90I, D123E, I135V, S162A, K173T, Q174X, D177E, T200A, Q207E, R211K, L228R, P243H, V245ECRF02_AG
 NJIH0146NJIH0146MF622697NRTINNRTIK70E, M184VA98G, K101KN, V108I, Y181CK20KR, V35T, K122E, I135V, T139TA, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, L228R, V245QCRF02_AG
 NJIH0145NJIH0145MF622696NRTINNRTID67DE, K70KE, M184V, K219KNA98G, K101KN, V108I, Y181CK20KR, V35T, K122E, I135V, T139A, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, L228LR, V245Q, T286A, E291D, V292I, I293V, S322A, I326V, G335DCRF02_AG
 NJIH0120NJIH0120MF622671NRTINNRTIA62AV, K65KR, K70KN, L74LI, M184VA98AG, K103N, V108I, P225PHK22KR, V35X, E36ED, T39TA, V60I, S68X, V90VI, K122V, I135L, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207E, V245QCRF02_AG
 NJIH0119NJIH0119MF622670NRTINNRTI K103N, V108IK22KR, V35T, E36ED, V60I, K122V, I135L, S162A, K173T, Q174K, D177E, M184X, T200A, Q207E, V245Q, A272P, L283I, T286TA, E291D, V292I, I293V, P294T, S322A, I326IV, G335DCRF02_AG
 NJIH0106NJIH0106MF622657NRTINNRTIA62V, K65R, V75I, Y115F, M184VK101E, V108I, Y181CK20R, V21I, E28K, V35I, K49R, D123E, S162A, F171Y, K173T, Q174K, D177E, V179X, T200A, I202V, R206K, Q207X, R211N, E224D, V245Q, E248D, D250ECRF02_AG
 NJIH0105NJIH0105MF622656NRTINNRTIA62V, K65R, V75I, Y115F, M184VK101E, V108I, Y181CK20R, V21I, E28K, V35I, E40EQ, K49R, D123E, S162A, F171Y, R172RK, K173T, Q174K, D177E, V179X, T200A, I202V, R206K, Q207E, R211N, E224D, V245Q, E248D, D250ECRF02_AG
 NJIH0070NJIH0070MF622621NRTINNRTIK70E, Y115YF, M184VV108I, Y181CE6N, K11T, V35T, E36A, T39K, K43E, K101KQ, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, H221Y, L228R, V245K, D250E, S251HCRF02_AG
 NJIH0069NJIH0069MF622620NRTINNRTIM184VV108I, Y181CE6N, K11T, V35T, E36A, T39K, K43E, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, H221Y, V245K, L283I, I293V, P294T, S322T, G335DCRF02_AG
 NJIH0042NJIH0042MF622593NRTINNRTIK65R, M184V, K219EK101E, V108I, Y181CK20KR, V35T, V60I, S68X, L109LI, D121Y, K122E, I135R, S162A, K173T, Q174K, D177E, V179VM, G196GR, T200A, I202V, E204M, Q207E, R211K, F214L, H221Y, V245QCRF02_AG
 NJIH0041NJIH0041MF622592NRTINNRTIK65R, M184VV108I, Y181CV35T, V60I, K82R, D121Y, K122E, I135R, S162A, K173T, Q174K, D177E, V179X, G196E, T200A, I202V, E204M, Q207E, R211K, F214L, H221Y, V245Q, Q278E, T286A, E291D, V292I, I293V, P294T, E297R, S322T, G335DCRF02_AG
Nii-Trebi (2017)09GH.NJ3409GH.NJ34LC269862NRTINNRTIM184VK103N, V108IK13KR, V35T, E36D, K49R, K122E, I135T, S162A, E169Q, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, V245Q, E248N, S251CCRF02_AG
Rhee (2017)AP09-230KAN304620 TDF, 3TCEFVK65R, K70N, M184VV108I, Y181CV35T, S68G, T69S, I135V, I142V, S162T, K173S, Q174K, D177E, V179I, T200A, Q207D, D218ECRF02_AG