<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V106I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 12
Patients 24
Isolates 24
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Delgado (2008)GH_212GH_212EU178041AZT, 3TCNVPD67E, M184V, T215TNSYY181CV35T, E36D, V60I, V106I, K122E, D123K, I135V, S162T, K166R, K173T, Q174K, D177E, I178L, T200A, Q207D, H221Y, V245Q, T286A, E291D, I293V, P294T, S322TCRF02_AG
Hawkins (2009)R103ZZR103FJ931294D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, Y188CE6K, K11T, V35T, E36D, V106I, K122E, D123N, I135R, S162A, K173I, Q174N, D177G, T200A, Q207E, V245Q, E248D, K281R, R284K, T286A, E291D, V292I, I293V, S322A, I326VCRF02_AG
Aghokeng (2013)HJ3293HJ3293JX982994NRTINNRTI Y188LV35T, T39L, V106I, K122P, D123E, I135V, I159IL, S162A, K173T, Q174K, N175Y, P176Q, V189VI, T200A, Q207E, R211K, F214FL, V245Q, E248Q, D250E, K281R, T286A, E291D, I293V, P294T, S322T, I326V, G335D, I341V, R356K, M357K, G359S, K366R, T369V, A371V, I375V, K390R, T403MCRF02_AG
Kebe (2013)SN1921HALDSN1921HALDHM002533NRTIEFVM184VY188LK43Q, S68SG, V106I, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, S322TCRF02_AG
 SNA3-139SNA3-139JN193500NRTINVPM184VA98AG, K101E, V108I, G190AV35T, E36D, V60I, K102Q, V106I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207ECRF02_AG
Theys (2013)93309330KC219686NRTI, TDFNNRTIM41L, M184V, T215FV179E, Y188LV90I, V106I, K122E, I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LCRF02_AG
Thiam (2013)18-HALD18-HALDJN673605NRTINNRTID67T, T215A, K219EK103N, M230LV35T, T39A, V60I, K64H, T69N, V106I, I135V, S162A, K173T, Q174K, D177E, I178IM, T200A, E203K, Q207E, R211K, P243T, V245Q, V276I, T286A, E291D, I293V, P294T, S322TCRF02_AG
Aghokeng (2014)TG-5-347TG-5-347KC350316NRTINNRTIM184VK101E, G190SV35T, V106I, I135IV, I142IT, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211RK, V245Q, P247A, A272P, T286A, E291D, V292I, I293V, P294T, G335D, R356K, M357KR, G359S, A371V, I375V, K390R, T403M, E413DCRF02_AG
 TG-3-526TG-3-526KC350074NRTINNRTIK70R, M184V, K219QA98G, K103N, Y181CV35T, T39M, K104R, V106I, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, L228R, V245Q, E248D, K275R, T286A, V292I, I293V, S322T, G335D, K347Q, R356K, M357R, G359S, A376S, K385R, K390R, A400TCRF02_AG
 CI-1-213CI-1-213KC350062NRTINNRTIM184VK103TV106I, K122E, I132L, I135T, S162A, K173A, Q174K, D177E, T200A, Q207E, R211KCRF02_AG
 CI-1-640CI-1-640KC350409NRTINNRTIM184VA98AG, K103N, G190AV21I, K32R, V35T, E36D, K64R, V106I, D121H, K122Q, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LCRF02_AG
 CM-1-343CM-1-343KC350183NRTINNRTIK70R, M184VV179E, Y188LV35T, T39A, E40D, K46Q, K49R, I50V, V60I, T69N, V106I, I142V, S162AD, K173V, Q174K, D177E, I178IM, T200A, Q207A, R211K, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, S322A, G335DCRF02_AG
Jenabian (2015)DR28DR28KF735834NRTINNRTIK65R, M184VY188FLK20KR, V35T, T39A, K46Q, S68KN, V90I, K104KR, V106I, I135V, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207E, R211K, V245DEHQ, A272P, L283I, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
Konou (2015)H1459H1459KT316117NRTINNRTIA62V, V75I, M184VY188CI31L, V35T, E36D, K49R, V90I, V106I, V118I, D123E, I135T, S162A, T165L, K173T, Q174A, D177E, I178F, T200A, Q207E, R211K, F214L, V245QCRF02_AG
Lam (2016)2101200621012006KR867960TDF, FTCEFVK65R, M184VV179E, Y188LK20KR, E28A, V35T, E36D, V60I, S68G, V106I, K122V, I135V, S162A, K173I, Q174K, D177E, T200E, E203K, Q207E, R211K, P243T, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
Chaplin (2017)NJIH0358NJIH0358MF622909NRTINNRTID67N, K70R, M184V, K219KEA98G, K103N, G190AV35T, E36D, S68SR, V106I, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207E, R211X, T215X, E224D, L228LR, V245T, E248NCRF02_AG
 NJIH0236NJIH0236MF622787NRTINNRTID67N, K70R, M184V, T215F, K219QK103N, Y181CK20R, V35T, E40D, K49R, V60I, T69TN, V106I, T139R, S162A, K173T, Q174K, T200A, I202V, Q207D, L228H, V245RCRF02_AG
 NJIH0235NJIH0235MF622786NRTINNRTID67N, K70R, M184V, T215F, K219QK103N, Y181CK20R, V35T, E40D, K49R, V60I, T69TN, E89X, H96N, V106I, T139R, S162A, K173T, Q174K, T200A, I202V, Q207X, L228H, V245R, K281R, L283LI, T286A, A288S, V292I, I293V, E297K, S322T, I329V, G335NCRF02_AG
 NJIH0134NJIH0134MF622685NRTINNRTIK70E, M184VY181CI31L, V35T, E36D, T39A, V106I, K122E, I135IV, I142V, S162A, K173R, Q174E, D177E, T200A, Q207G, R211K, F214L, H221Y, L228RCRF02_AG
 NJIH0133NJIH0133MF622684NRTINNRTI Y181C, Y188YCI31L, V35T, E36D, T39A, V106I, K122E, I135V, I142V, S162A, K173R, Q174E, D177E, T200A, Q207X, R211K, F214L, K281R, T286A, E291D, I293V, P294T, S322T, I326V, G335DCRF02_AG
 NJIH0116NJIH0116MF622667NRTINNRTIA62AV, V75I, M184I, K219EG190A, M230LV35T, E36D, V90I, K103X, V106I, K122E, D123N, I135V, I142IV, S162A, K173T, Q174K, D177E, I178L, G196X, T200A, E203EK, Q207E, R211K, P243T, V245Q, E248DCRF02_AG
 NJIH0115NJIH0115MF622666NRTINNRTID67G, V75IK103N, G190AI31L, V35T, E36D, V90I, K101Q, V106I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178L, G196E, T200A, Q207E, R211K, P243T, V245Q, E248D, K275R, T286A, E291D, V292I, I293V, P294T, D320E, S322T, G335DCRF02_AG
 NJIH0049NJIH0049MF622600NRTINNRTIK65R, K219EK103N, Y181CP4S, K20R, V35T, T39N, E40D, V60I, T69S, V106I, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251N, A272P, V292I, I293V, P294T, K311R, I326V, G335DCRF02_AG
Rhee (2017)4919249192KY386800TDF, FTCEFV  V35I, E36D, K49KR, V90VI, V106I, K122E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, V245Q, D250DA, S251SN, A272P, K281KR, T286A, E291D, V292I, I293V, P294A, S322T, I326V, G333GECRF02_AG