<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation V106A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 16
Patients 48
Isolates 50
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Sylla (2008)D635D635_C1DQ991663AZT, 3TC, D4TNVPM184V, N348IV106AV35T, E36D, K49R, D123N, I135V, T139A, I142F, S162A, T165H, K173T, Q174G, D177E, G196E, T200A, Q207E, V245Q, K277R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377V, K390R, A400T, T403M, E432D, V435ACRF02_AG
  D635_C2EF588325AZT, 3TC, D4TNVPM184V, N348IV106AV35T, E36D, T58S, I135V, T139A, I142F, S162A, T165H, K173T, Q174G, D177E, G196E, T200A, Q207E, V245Q, K277R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377V, K390R, A400T, T403M, E432D, V435ACRF02_AG
 D673D673_C1DQ991672AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554N, K558RCRF02_AG
  D673_C2DQ991673AZT, 3TCNVPM41L, T69D, M184V, T215YV106A, V108I, F227L, M230LV35T, E44D, S105V, L109I, K122E, D123N, S162A, S163R, M164H, T165D, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534SCRF02_AG
Hawkins (2009)P614ZZP614FJ931128D4T, 3TCNVPA62AV, V75I, Y115F, M184VV106A, Y181CK20R, V21I, V35T, E36D, V60VI, V90I, D121H, K122E, D123E, I135V, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207E, R211K, H221Y, P243T, V245Q, K277Q, T286A, E291D, I293V, E297R, S322T, I326VCRF02_AG
 Q187ZZQ187FJ931196D4T, 3TCNVPA62AV, M184VV106A, F227FLV35T, T39TA, E40D, K43R, S68SG, I135V, E138A, S162A, K173T, Q174K, T200E, Q207D, R211K, V245E, S251SR, K275R, T286A, E291D, I293V, P294T, E312EG, V317VA, S322T, I326VCRF02_AG
 Q440ZZQ440FJ931262D4T, 3TCNVPM41L, D67DN, M184V, L210W, T215YV106A, F227LV35T, K49R, L109I, V118VI, K122E, S162A, K173T, Q174K, D177E, T200A, I202V, E203K, Q207E, H208HY, H221Y, V245EK, E248D, A272P, T286A, V292I, I293V, S322TCRF02_AG
 R109ZZR109FJ931359TDF, 3TCNVPA62V, K65R, Y115F, M184VV106A, F227LT27S, K32R, V35T, T39S, K49R, W88C, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, V245K, D250E, K277R, K281R, L283I, V292I, I293V, S322A, I326VCRF02_AG
 Q998ZZQ998FJ931364AZT, D4T, 3TCNVPM41ML, D67DN, K70KR, M184V, T215Y, K219KEV106A, F227LV35T, V60I, K101Q, I135V, S162A, K173A, Q174K, D177E, T200E, E203GR, Q207D, R211K, V245T, D250E, A272P, T286A, I293V, P294T, S322TCRF02_AG
 R266ZZR266FJ931442TDF, 3TCNVPK65R, Y115F, M184VV106A, Y181CP4T, E6EK, V35T, E36D, T39I, K49R, S68SG, K122E, D123E, I135V, S162A, K173T, Q174QKR, D177E, T200A, Q207E, R211K, V245Q, D250E, S251H, L283I, E291D, V292I, I293V, P294T, L295M, S322TCRF02_AG
Burda (2010)07BDHS07707BDHS077GQ344980D4T, 3TCNVPD67N, K70R, L74I, M184V, T215Y, K219EV106A, P225H, F227LV35T, R78P, L109I, K122E, I135V, S162A, K173I, Q174K, D177E, T200A, I202V, R211K, A272P, K275R, K277R, T286A, I293V, P294T, S322V, G335D, M357K, G359S, A371V, I375V, I382L, K390R, A400T, T403Q, E432D, V435E, A437VCRF02_AG
Germanaud (2010)55885588 AZT, 3TCNVPM184VV106A, F227LV35T, V60I, I135L, S162A, K173I, Q174K, D177E, I178V, G196E, T200A, E204G, Q207E, L209LF, V245QCRF02_AG
Aghokeng (2011)SK2088-M18SK2088-M18HQ8644483TC, D4TNVPD67DN, K70KR, M184VV106AK20KR, E28EK, K32KE, V35K, K49R, V60I, K101A, I135L, S162A, K173T, Q174N, D177E, T200A, Q207E, V245Q, E248DN, A272AP, K277R, T286A, A288ST, E291D, V292I, I293V, P294TCRF02_AG
 SK3028-M24SK3028-M24HQ864462D4T, 3TCNVPK70KR, M184VV106A, F227FLK20KR, V35T, E40D, K49KR, K104R, K122E, D123S, S162A, K173KAET, Q174AE, D177E, T200A, I202IV, Q207E, R211K, F214L, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V, P294TCRF02_AG
Dagnra (2011)08TG.T306108TG.T3061FR715264D4T, 3TCNVPM184VV106A, F227LV35T, E36D, K49R, V60I, S105L, D121Y, K122E, D123E, I135V, S162A, K173T, Q174E, D177G, T200A, Q207E, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, R356K, M357R, R358K, G359S, K366R, T369V, A371V, I375V, S379G, K390R, T403M, E432D, V435LCRF02_AG
 08TG.E502408TG.E5024FR715275D4T, 3TCNVPM184VV106A, F227LK20R, V35T, V60I, V90I, K122E, D123E, I135V, S162Q, K173T, Q174K, D177E, V179I, G196E, T200A, Q207A, R211K, V245Q, A272P, K275R, T286A, E291D, V292I, I293V, P294A, G335D, R356K, M357K, G359FS, A371V, I375V, T377LS, K390R, A400T, T403M, E432D, V435ICRF02_AG
 08TG.C700308TG.C7003FR715286D4T, 3TCNVPM184VV106A, F227LV35T, L109LI, K122E, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, P243T, V245Q, T286A, E291D, S322A, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, K390R, A400AT, T403M, E432DCRF02_AG
Kebe (2013)SNA3-250SNA3-250HM002518NRTINVPM184VV106A, F227LQ23QH, V35T, K49R, S68G, V90I, K122E, D123E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, D250DECRF02_AG
 SNA3-324SNA3-324HM002523NRTINVP V106AV35T, V60I, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, F214L, P243A, V245Q, D250ECRF02_AG
Theys (2013)5117851178KC221466TDF, FTCNVPK65N, K70KR, Y115YFV106A, Y181CS48ST, K49R, S162A, K173T, Q174K, D177E, T200A, Q207E, F214LCRF02_AG
 3990139901KC221181NRTI, TDFNNRTID67N, K70RV106AV90G, K101Q, K122E, D123G, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214LCRF02_AG
Aghokeng (2014)CI-1-401CI-1-401KC350381NRTINNRTIM184VV106AV90I, K122E, E138Q, S162A, K173T, Q174A, I178M, T200A, Q207E, I244V, V245QCRF02_AG
 CI-1-281CI-1-281KC350041NRTINNRTID67DG, M184MIV106A, G190A, F227LV35T, E36D, V60I, D123DE, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245QCRF02_AG
 TG-2-079TG-2-079KC350053NRTINNRTIM184VV106A, G190A, F227LV35T, T39A, D121H, K122E, I135V, T139L, S162T, K173I, Q174K, D177E, I178L, T200A, Q207E, H221HY, V245E, K275R, K277R, T286A, E291D, V292I, I293V, P294T, L295M, S322A, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, E399D, T403MCRF02_AG
 CM-3-148CM-3-148KC350346NRTINNRTIM184V, T215TNSYV106A, F227LM16MV, V35T, E36D, T39K, K43E, E53ED, T58S, S68G, L109LI, K122E, D123N, I135V, E138A, S162A, K173A, Q174K, N175Y, T200A, K201KIR, E203EA, Q207D, R211K, F214FL, P243T, V245Q, V254VI, A272AP, K281R, T286A, E291D, V292I, I293V, S322T, G335DCRF02_AG
 TG-1-487TG-1-487KC350285NRTINNRTIK70R, M184V, K219Q, N348IV106A, V108I, F227LV35T, E36D, S105I, D121H, K122E, I135V, S162A, Q174E, D177E, T200A, E203D, Q207E, R211K, L228R, P243T, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403M, E432DCRF02_AG
 CI-1-41-CI-1-41-KC350045NRTINNRTI V106AS162A, F171Y, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, D250E, S251DCRF02_AG
 TG-2-424TG-2-424KC349987NRTINNRTIM184VV106A, F227LV35R, E36D, T39A, V60I, S68G, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, T286A, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, A400T, T403M, E432DCRF02_AG
 CM-1-150CM-1-150KC350323NRTINNRTI V106A, F227LV35T, T39S, K102Q, I135V, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, T286A, E291D, I293V, S322T, I326V, G335DCRF02_AG
 CM-2-072CM-2-072KC350334NRTINNRTIM184V, T215FSV106A, F227FL, M230MLV35T, T39R, K43E, K49R, S68G, V90I, K122E, S162AD, K173T, Q174K, D177E, T200A, Q207K, R211K, V245N, K281R, T286A, E291D, V292I, I293V, P294T, K311R, S322TCRF02_AG
 TG-5-478TG-5-478KC350302NRTINNRTIM41L, L74V, M184V, L210W, T215YV106A, V179E, F227LK20R, V35T, E36D, L109I, V118I, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, E203K, Q207D, H208Y, R211K, H221Y, V245K, K281R, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, A376S, K390R, E399D, A400T, T403TM, E432DCRF02_AG
 TG-1-486TG-1-486KC350279NRTINNRTIM184VV106A, E138EKQ, F227FLV35T, E36D, K49R, V60I, R83RK, V90I, A98S, D123E, I135V, S162A, T165I, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, K390R, E399D, A400AT, T403MCRF02_AG
Grossmann (2015)SE602020SE602020KP411844NRTINNRTIM184VV106A, F227LP4S, V35T, T39A, E53D, S68G, A98S, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, D237N, V245Q, E248D, A272P, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, K390R, A400T, T403M, E432D, R448K, V467I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527Q, E529D, A534S, A554NCRF02_AG
Jenabian (2015)DR42DR42KF735846NRTINNRTIL74V, Y115YF, M184V, T215F, K219NK101H, V106A, G190A, F227L, M230LV35T, T39M, E53ED, V60I, S68G, L109I, E138EQ, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, L228HQ, V245Q, A272P, I274V, K275R, Q278HY, T286A, E291ED, V292VI, I293V, P294T, E297KR, E312D, S322T, G335DCRF02_AG
 DR08DR08KF735819NRTINNRTID67G, K70R, M184I, T215F, K219QV106A, F227L, M230LV35T, T39A, K49R, S68G, V90I, L109I, K122E, D123N, S162A, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, L228H, V245Q, E248D, T286A, E291D, I293V, P294T, S322T, D324E, I326V, G335DCRF02_AG
Konou (2015)H566H566KT316171NRTINNRTIM184VV106A, P225HV35T, E36D, T39K, S162A, K173T, Q174R, V179I, V189VI, T200A, I202V, Q207E, R211K, P243T, V245Q, E248DCRF02_AG
 H672H672KT316166NRTINNRTIM184VV106A, G190A, P225HV35T, V60I, K64R, S105T, S162A, K173T, Q174A, D177E, T200A, Q207E, F214LCRF02_AG
 H1420H1420KT316157NRTINNRTIM41L, M184V, T215FV106A, V179E, F227LK11T, V35T, E36A, T39K, K43E, V60I, S68G, V90I, K102Q, K122E, D123N, I135V, E138A, S162M, K173A, Q174K, D177E, I178L, T200A, I202V, Q207D, R211K, D237A, V245QCRF02_AG
 H1404H1404KT316104NRTINNRTID67N, K70R, M184V, T215F, K219QV106A, F227LE6K, V35T, T39M, A98AS, K122P, I135V, S162A, K173T, Q174K, D177E, G196E, T200A, E203A, Q207K, H208HY, R211E, F214L, K223Q, L228LH, V245Q, E248DCRF02_AG
 H706H706KT316084NRTINNRTIM41L, T69D, M184V, L210W, T215YV106A, Y181V, G190AV35T, K49R, V60I, K122E, D123N, I135V, S162A, K173T, Q174K, N175Y, T200A, K201R, Q207D, L228R, V245KCRF02_AG
 H967H967KT316037NRTINNRTID67DN, K70R, M184V, K219KQV106A, F227LK20KR, V35T, T39TA, V60I, K122E, I135L, E138Q, I142IV, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, Q222H, K223N, V245QCRF02_AG
 H458H458KT316022NRTINNRTIM184VV106A, F227LK20R, V35T, T39A, S68G, K104R, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, P243T, V245Q, D250NCRF02_AG
 H443H443KT316013NRTINNRTIM41L, M184V, T215FV106A, F227LV35T, T39A, S68G, K101Q, D123E, I135V, I142V, S162A, Q174E, D177E, V179I, T200A, I202V, Q207K, R211A, H221Y, W229R, P243T, V245QCRF02_AG
 H347H347KT316008NRTINNRTIM41ML, M184V, T215YK101H, V106A, P225PHV35T, K102KR, K122P, I135V, S162A, E169X, K173S, Q174K, D177E, I178IL, T200A, Q207E, F214L, P243A, V245QCRF02_AG
Rokx (2015)M38000M38000KY315764TDF, FTCEFVD67NK103N, V106A, P225HK22R, V35T, K66I, K122E, I135V, S162A, K173T, Q174K, D177E, I178V, G196E, T200A, I202V, Q207G, F214L, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322A, I326V, I329VCRF02_AG
Lam (2016)2101201221012012KR867956TDF, FTCNVPD67N, K70EG, M184V, T215FV106A, Y181C, F227LT7TA, K20KR, V35T, S105T, L109I, D121H, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, I202IV, Q207A, R211EK, H221Y, P225S, V245Q, T286A, E291D, V292I, I293V, P294T, E312D, S322T, I326V, G335DCRF02_AG
 2101201621012016KR867965TDF, FTCNVPK65R, K70T, Y115F, M184VV106A, F227LT27S, V35T, T39A, E40K, K46M, V60I, S68G, V90I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, I202IV, Q207E, R211K, V245E, E248D, D250DE, A272P, T286A, E291D, V292I, I293V, P294V, S322T, G335DCRF02_AG
Chaplin (2017)NJIH0240NJIH0240MF622791NRTINNRTID67DN, K70KR, M184V, T215TI, K219KEV106A, P225PHK20KR, V35T, K101X, K122KE, D123E, I135V, S162A, K173A, Q174K, D177E, T200E, E203K, Q207E, R211A, V245Q, E248NCRF02_AG
 NJIH0239NJIH0239MF622790NRTINNRTIM184VV106AV35T, K101Q, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, E203K, Q207E, R211A, V245Q, E248N, K275R, Q278N, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG
Rhee (2017)4196041960KY386710TDF, FTCNVPK65R, Y115FV106A, E138KV35T, E36D, T39L, W71W*, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, D250N, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335DCRF02_AG

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