<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation K103S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 13
Isolates 13
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2006)48-12261226-30417DQ877758NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215Y, K219EK103S, V108I, G190AP4Q, K20R, V35T, T39A, E44D, V60I, V118I, K122E, D123N, I135V, S162A, K173V, Q174K, D177E, I178M, Q197L, T200A, E203V, Q207E, K223Q, L228H, P243T, V245Q, T286A, I293V, P294T, S322A, G335D, M357K, R358K, G359S, A371V, I375V, A376T, T377M, T386A, K390R, E399D, A400TCRF02_AG
Hawkins (2009)Q975ZZQ975FJ931318D4T, 3TCNVPM184VK103S, G190AV35T, V60I, K122E, D123S, I135V, S162A, K166KR, K173I, Q174K, D177E, T200A, Q207AS, R211S, V245E, S251A, A272P, K277R, T286A, E291D, V292I, I293V, S322TCRF02_AG
Theys (2013)5539955399KC222012NRTI, TDFNNRTIM184V, T215IK103S, G190AK122E, I135V, I142V, S162A, K173A, Q174K, D177E, T200A, Q207E, F214L, L228QCRF02_AG
 90679067KC219649NRTI, TDFNNRTIM184IK103S, P225HS68G, K102KR, D123N, I135L, S162A, K173T, Q174K, D177E, T200A, Q207E, R211KCRF02_AG
 2939029390KC220678NRTI, TDFNNRTIM41L, M184V, T215FA98G, K103S, G190AK122E, I142V, S162A, K173A, Q174K, D177E, T200A, Q207E, F214L, L228QCRF02_AG
Theys (2013)BM13950BM13950 AZT, 3TCEFVM41L, D67DN, M184V, T215Y, K219KEK103S, G190AE28A, V35T, T39TA, V60I, K122E, D123S, I135T, K173IL, Q174K, D177E, T200A, Q207EK, R211K, V245Q, T286A, E291D, V292I, I293V, P294A, S322T, I326VCRF02_AG
 147268147268 AZT, 3TCNVPM184VK103S, G190AE6EK, M16MT, V35M, E36D, T39A, S48T, K49KR, R83K, K122E, D123DN, I135V, S162A, E169ED, K173I, Q174K, D177E, T200A, Q207E, R211K, V245Q, K277R, T286A, I293V, P294A, S322TCRF02_AG
Aghokeng (2014)TG-3-226TG-3-226KC350280NRTINNRTIM184VK103S, G190AV35T, E36D, D123E, I135V, S162A, K173A, Q174K, D177E, T200E, Q207E, R211K, P243T, V245Q, A272P, Q278N, T286A, V292I, E297A, S322T, I326V, R356K, M357K, G359S, A371V, I375V, V381I, K390R, A400T, T403MCRF02_AG
 TG-1-018TG-1-018KC350079NRTINNRTIM41L, M184V, T215YK103S, G190AV35T, E36N, T39E, K102Q, K122E, D123N, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, E203EK, Q207E, R211A, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357KR, G359S, A371V, I375V, T377V, K390R, A400T, T403MCRF02_AG
Konou (2015)H313H313KT316052NRTINNRTIM184VK103S, G190AV35T, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245QCRF02_AG
 H439H439KT316012NRTINNRTIM41L, M184V, L210W, T215FK103S, G190AV35T, E36D, T39N, K43KQ, E44ED, V90I, K102H, K122P, I135V, S162A, K173X, Q174K, D177E, T200A, Q207E, R211RK, V245QCRF02_AG
Lam (2016)2103201721032017KR867968AZT, 3TCEFVM41ML, M184V, T215YK103S, G190AV35T, E36ED, V60I, L109LI, I135V, S162AT, K173T, Q174K, N175NY, D177E, I178IM, T200A, Q207E, R211K, P243T, V245K, A272P, T286A, E291D, V292I, I293V, P294T, S322T, G335DCRF02_AG
Chaplin (2017)NJIH0320NJIH0320MF622871NRTINNRTID67G, T215FK103S, G190AK20R, V35T, T39K, K43E, V60I, S68SG, V90I, I135IV, Q174D, D177E, T200A, Q207E, P243PS, V245E, E248DCRF02_AG