<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation K101R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2006)48-30363036-30310DQ877947NRTINNRTID67N, T69D, K70R, M184I, K219HA98G, V108I, Y181C, G190AV35T, E36A, T39K, K46M, V60I, V90I, K101R, K122E, D123S, S162A, S163T, T165I, Q174E, D177E, T200A, E203N, Q207K, L210I, D218E, V245Q, K275KQ, K277R, T286A, E291D, I293V, P294T, E297EK, E300EQ, S322T, G335D, R356K, M357K, G359S, A360I, A371V, I375V, K390R, K395RCRF02_AG
Hawkins (2009)Q810ZZQ810FJ931259AZT, D4T, 3TCNVPK65R, K70T, F77FL, F116Y, Q151M, M184VK103N, Y181CV35T, T39TI, V60VI, S68G, T69TI, K101R, K122E, D123N, I135V, S162A, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, F214L, P243S, V245Q, E248ED, K281KR, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
Germanaud (2010)55935593 AZT, 3TCNVPM184VK103N, Y181CV35T, K43E, K49R, N57H, V90I, K101R, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I180V, T200A, Q207E, Q222R, V245QCRF02_AG
Sigaloff (2011)HIV103634HIV103634JN132356AZT, 3TCNVPD67N, K70R, M184VY181CV35K, K43N, K49R, K101R, K122E, I135V, S162T, K173T, Q174E, D177E, T200A, Q207N, R211K, H221Y, V245Q, D250E, K277R, K281R, T286A, E291D, V292I, I293VCRF02_AG
Kebe (2013)SNA3-045SNA3-045JN193483NRTIEFVM41L, D67N, L74V, M184V, L210W, T215Y, K219NK103N, V179F, Y181C, G190AV35T, E36D, V60I, K101R, V118I, I135T, K173T, Q174K, D177E, G196E, T200A, E203K, Q207E, R211K, K223Q, L228HCRF02_AG
Rawizza (2013)PJ9581PJ9581KF241512NRTINNRTIK65R, F116Y, Q151M, M184VK103N, Y181CK20R, E28D, K32KQ, V35K, E36D, T39A, S68G, K101R, D123E, I135T, S162A, T165I, E169D, K173T, Q174K, D177E, G196E, T200A, Q207E, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
Theys (2013)5270852708KC221531NRTI, TDFNNRTI  V60I, T69TN, K101R, I135V, S162A, E169D, K173A, Q174N, D177E, I178V, T200A, Q207E, R211KCRF02_AG
Aghokeng (2014)TG-2-282TG-2-282KC350195NRTINNRTIM184V, T215FY181CV35T, K49R, V60I, K101R, K122E, I135T, T139R, S162T, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, K277R, K281R, E291D, I293V, P294T, E297Q, S322A, G335D, F346L, R356K, M357K, G359S, A371V, I375V, K390R, K395R, A400T, T403MCRF02_AG
 CM-2-070CM-2-070KC350333NRTINNRTIM184VY181CV35T, K49KR, K101R, I135V, S162T, K166R, K173T, Q174K, D177E, T200A, Q207E, R211K, V245E, A272P, T286A, E291D, V292I, I293V, P294T, N306D, S322A, I326V, G335DCRF02_AG
Jenabian (2015)DR41DR41KF735845NRTINNRTIM41ML, D67N, K70R, M184V, T215Y, K219KEK103N, Y181CE6EK, E28EK, V35T, T39L, K101R, K102Q, K122E, I135V, T139A, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245K, E248D, K281R, T286A, V292I, I293V, E297K, S322T, I326V, G335DCRF02_AG
 DR21DR21KF735828NRTINNRTIM41L, M184V, T215FK103NV35K, E36D, T39TA, K43E, V60VI, K101R, K102R, K122E, D123S, I135T, S162A, K173T, Q174A, D177E, T200A, Q207E, R211K, V245Q, L283I, E291D, I293V, P294T, S322A, G335DCRF02_AG