<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation K101Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 12
Patients 23
Isolates 23
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Weber (2005)M83283M83283AY714432AZT, 3TCNVP  V35K, E36D, T39A, E40ED, M41MR, D86DE, F87FL, K101Q, K122P, S162A, K173T, Q174K, D177E, T200A, Q207E, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
Sylla (2008)A2628A2628_C2DQ991634AZT, 3TCEFVM184VK103N, P225HV35T, K101Q, I135V, T139A, K173T, Q174K, D177E, I178M, I195L, T200A, Q207D, R211K, V245Q, E248D, T286A, V292I, I293V, S322A, I326V, G335D, Y342F, R356K, M357K, G359S, A371V, I375V, K390R, K395R, A400T, T403M, I411L, K431T, E432DCRF02_AG
Hawkins (2009)R120ZZR120FJ931316D4T, 3TCNVPM184V, T215FYK103NK20R, E28K, V35T, E36D, T39M, K43KQ, K49R, V60I, S68SG, K101Q, K122Q, D123E, I135T, S162A, K173T, Q174R, D177E, I178M, T200A, Q207D, V245Q, A272P, V276I, Q278E, L283I, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q998ZZQ998FJ931364AZT, D4T, 3TCNVPM41ML, D67DN, K70KR, M184V, T215Y, K219KEV106A, F227LV35T, V60I, K101Q, I135V, S162A, K173A, Q174K, D177E, T200E, E203GR, Q207D, R211K, V245T, D250E, A272P, T286A, I293V, P294T, S322TCRF02_AG
Germanaud (2010)56005600 AZT, 3TCNVPM184VK103N, Y181C, G190AL26W, V35T, E40D, V60I, V90I, K101Q, I135V, S162A, K173A, Q174K, D177E, Q207E, V245QCRF02_AG
Charpentier (2011)CR-31CR-31FJ688237AZT, 3TCNNRTIK65R, D67N, T69~, V75VI, F77L, Q151M, K219EK103KN, Y181C, G190A, F227FL, K238TL34I, V35T, T39M, E40D, S68G, K101Q, K122E, I135IM, S162A, R172K, K173A, Q174K, N175Y, D177E, T200E, K201R, E203Q, Q207DN, F214L, K223EQ, L228LR, V245E, K249KR, T286A, E291D, I293V, P294T, S322ACRF02_AG
 CR-25CR-25FJ688231AZT, 3TCNNRTIM184V, T215YK103N, P225HE28KR, V35T, E36D, V60I, S68G, K101Q, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, E297EK, S322T, I326VCRF02_AG
 CR-48CR-48FJ688254AZT, 3TCNNRTIK70R, M184V, T215F, K219QK103RS, V108VI, Y181C, G190AV35T, E36ED, T69N, K101Q, S162AT, K173T, Q174K, D177E, I178M, T200A, Q207E, R211Q, L228R, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
Dagnra (2011)08TG.T304908TG.T3049FR715263D4T, 3TCNVPV75I, M184VV108VI, G190AV35T, E36D, V60I, K101Q, D123E, I132L, I135V, S162A, Q174D, D177K, T200A, Q207E, L210M, R211K, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357R, G359S, A360T, V365VI, A371V, I375V, A376AG, S379SG, K390R, K395R, W402WC, T403M, E432DCRF02_AG
Afonso (2012)ANG21ANG21JN937036NRTINNRTIM184VY181CE6A, V35T, K101Q, K122E, S162A, K173T, Q174K, T200A, Q207E, V245Q, D250E, S251HCRF02_AG
Fourati (2012)92601269260126JQ395586NRTINNRTI  K22L, V35T, E36D, T39M, V60I, K101Q, K122V, I135V, S162A, R172K, K173A, Q174K, D177E, T200A, Q207E, R211KCRF02_AG
Rawizza (2013)LN0911LN0911KF241494NRTINNRTI  V35T, E36D, K43KN, E44ED, K101Q, K122E, I142IT, S162A, K173T, Q174A, D177G, T200A, Q207EIKV, R211K, V245Q, S251N, K277Q, K281R, E291D, V292I, I293V, P294T, E297K, H315HNCRF02_AG
Theys (2013)39543954KC219325TDF, 3TCEFVK65R, K70KT, Y115FY181YC, G190VE40D, K49R, K66R, S68G, E89Q, V90I, K101Q, K122E, I135K, S162A, E169D, K173R, Q174K, D177E, T200A, Q207G, R211K, H221YCRF02_AG
 3990139901KC221181NRTI, TDFNNRTID67N, K70RV106AV90G, K101Q, K122E, D123G, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214LCRF02_AG
 40694069KC219339NRTI, TDFNNRTIM184V, K219KRK103N, P225HK49KR, K101Q, K122N, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211RKCRF02_AG
 66016601KC219500NRTI, TDFNNRTIM41L, M184V, T215FA98G, K103NV60I, S68G, K101Q, K122KEIV, D123DEKN, I135V, S162A, K173T, Q174KN, N175NY, D177DE, I178IM, I180IV, T200A, K201KI, Q207E, R211RKCRF02_AG
Theys (2013)143390143390 AZT, 3TCEFVD67G, T69D, K70R, M184V, T215YV179E, Y181C, G190AV21I, V35T, E36D, T39A, K46KQ, S68G, V90I, K101Q, K103R, L109I, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, A288G, E291D, V292I, I293V, P294A, S322T, I326VCRF02_AG
Aghokeng (2014)SN-3-351SN-3-351KC350094NRTINNRTIM184V, K219NK103N, Y181CE6D, V35T, E36D, K101Q, K102N, D123E, I135V, S162A, K173A, Q174K, D177G, T200A, Q207E, R211K, V245KCRF02_AG
 TG-1-013TG-1-013KC350039NRTINNRTIA62V, K65R, D67EY181C, G190AV35T, T39L, E40D, K101Q, K122P, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, K281R, T286A, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, T369A, A371V, V372M, I375V, A376S, K390R, A400AT, T403R, E404D, E413DCRF02_AG
 TG-5-542TG-5-542KC350303NRTINNRTIM184V, T215YA98G, Y181CK20R, T27S, V35T, E36D, T39K, K43E, K49R, V60I, S68G, K101Q, D121H, K122E, I135V, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, V245Q, E248N, R284K, T286A, E291D, V292I, I293V, S322T, Q334QP, G335D, M357R, G359S, K366R, A371V, I375V, T377L, S379A, K390R, A400TCRF02_AG
 CM-3-018CM-3-018KC350337NRTINNRTIM184V, T215YK103N, M230LE28K, K32E, V35K, T39L, V60I, S68G, K101Q, K122E, I135T, S162A, K173T, Q174K, D177E, I178L, T200A, Q207K, R211N, P243H, V245Q, K275R, V276IT, L283I, T286A, E291D, I293V, P294T, L295M, S322T, I329L, G335DCRF02_AG
 TG-2-055TG-2-055KC350273NRTINNRTIM184V, N348IY181CV35T, T39A, E40D, K101Q, I135V, A158T, S162A, F171Y, K173A, Q174K, D177E, I178M, V179A, T200E, Q207E, R211K, F214L, Q242K, P243A, V245E, E248D, V276I, K277R, L283I, T286A, E291D, I293V, P294A, K311R, S322T, R356K, M357R, G359S, A371V, I375A, T386I, K390R, A400T, T403M, E432D, V435ICRF02_AG
 CI-1-246CI-1-246KC350060NRTINNRTIM184VE138EKQ, G190ST27TA, V35VI, S68G, K101Q, K122E, S162A, Q174E, D177E, I178M, T200A, E203D, E204K, Q207D, V245VELQ, E248EDCRF02_AG