<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation K101E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 15
Patients 45
Isolates 45
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patALC02_ALC723AJ577727AZT, DDI, 3TC, D4T, ABCNVPM41L, D67N, L210W, T215YK101E, G190AV35T, E36D, T39K, K43A, E44D, V60I, K104R, D121H, K122E, D123S, I135R, I142V, S162Y, K173L, D177E, I178L, V179I, Q207ACRF02_AG
Non-B Workgroup (2005)PL3439255893AY901524D4T, DDINVP, EFVK70E, V75AA98G, K101E, Y181C, G190AV35T, K73Q, I135R, S162A, K173IT, Q174K, D177E, I178M, T200A, Q207EG, R211K, H221Y, L228R, V245Q, T286A, E291D, V292T, I293V, P294A, Y318T, S322TCRF02_AG
 PL3498857183AY901532AZT, 3TCEFVM184VK101E, G190SV21VI, K32R, V35T, T39A, E40D, V60I, W88C, D123E, I132IV, I135V, E138Q, S162A, K173T, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248N, T286A, V292I, I293V, E297ACRF02_AG
Weber (2005)30239393023939AY677612AZT, DDI, D4T, 3TCEFVM41L, D67E, K70G, L210W, T215YK101E, Y181C, Y188LV8VG, T27S, V35T, T69S, W88C, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178LM, V179M, T200A, Q207D, H221Y, L228H, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, E297K, V317VA, S322T, I326VCRF02_AG
Laurent (2006)CK22-202CM2-2AM279451AZT, 3TCEFVM41L, M184IK101E, K103NE28K, V35T, T39A, K43N, V90I, K104R, K122E, D123N, I135V, S162A, K173I, Q174K, D177E, I178M, G196E, T200A, Q207G, V245Q, T286A, T290S, E291D, V292I, I293V, P294T, E312D, S322A, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, T403M, E404DCRF02_AG
Hawkins (2009)Q192ZZQ192FJ931200D4T, 3TCNVPM184VK101E, G190AV35T, D123E, S162A, K173T, Q174E, D177E, I178L, T200A, Q207D, R211K, F214FL, V245Q, A272P, K275Q, K277R, K281R, L283LF, T286A, E291D, I293V, P294T, S322T, I326VCRF02_AG
 Q806ZZQ806FJ931256D4T, 3TCNVPM184VK101E, K103NK20R, E28K, V35K, K122E, I135T, S162A, K173T, Q174R, T200A, I202V, Q207E, R211K, F214L, V245Q, K277R, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 Q829ZZQ829FJ931258D4T, 3TCNVPK65R, T69~, K219RK101E, Y181C, G190AL34LI, V35T, E36D, K49R, V90VI, K122E, I135V, S162A, E169Q, K173T, Q174K, D177E, T200A, Q207E, L228LHR, V245M, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 Q453ZZQ453FJ931264D4T, 3TCNVPK70R, M184VA98AG, K101E, G190AV21I, V35K, V60I, I135IV, S162SA, K173T, Q174K, D177E, I178V, V179I, T200A, Q207E, R211K, V245E, T286A, E291D, V292I, I293V, P294T, S322T, I326IV, I329VCRF02_AG
 Q430ZZQ430FJ931265D4T, 3TCNVPM184VK101E, G190AE28EA, V35T, E36D, Q85QE, I135V, S162A, K173T, Q174K, D177E, I178L, G196E, T200A, E203EG, Q207E, V241VI, P243T, V245Q, K281R, T286TA, E291D, I293V, S322A, I326VCRF02_AG
 Q438ZZQ438FJ931267AZT, D4T, 3TCNVPM41ML, D67DN, M184V, L210W, T215YA98AG, K101E, G190AE28K, V35T, T39E, S48T, V60VI, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, V179VI, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, S322T, D324ECRF02_AG
 Q942ZZQ942FJ931274D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AK20R, E28K, A33AG, V35I, V60VI, V90I, K102Q, I135IT, S162A, K173T, Q174K, T200A, Q207E, D218DE, L228LH, V245Q, D250E, K275R, V276VI, T286A, E291D, V292VI, I293V, P294T, S322TCRF02_AG
 Q944ZZQ944FJ931288D4T, 3TCNVPD67DN, K70R, M184V, K219QK101E, G190AP4S, V35T, V60I, K64R, V90I, I135V, E138A, S162A, K173T, Q174K, D177E, V179M, T200A, Q207D, R211K, D218DE, V245K, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R103ZZR103FJ931294D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, Y188CE6K, K11T, V35T, E36D, V106I, K122E, D123N, I135R, S162A, K173I, Q174N, D177G, T200A, Q207E, V245Q, E248D, K281R, R284K, T286A, E291D, V292I, I293V, S322A, I326VCRF02_AG
 R65ZZR65FJ931302TDF, 3TCNVPK65R, M184VK101E, Y181C, G190AV35T, S68N, V90VI, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, L295M, S322ATCRF02_AG
 R125ZZR125FJ931333AZT, D4T, 3TCNVPD67DN, K70KR, M184V, T215TFISK101E, G190AK11T, K20KR, E28K, V35T, V60I, V106VI, D121H, K122E, D123S, I135M, S162A, K173T, Q174K, D177E, I178FL, T200A, Q207E, R211K, V245T, A272P, T286A, E291D, V292I, I293V, P294T, S322TCRF02_AG
 R164ZZR164FJ931352D4T, 3TCNVPD67N, K70R, L74LI, M184V, T215TFIS, K219QA98G, K101E, G190AV35T, K49R, E53D, V60I, T69N, I135V, S162AE, K166KR, K173M, Q174K, N175NY, D177E, I178IM, Q197IKMN, T200A, Q207E, R211K, L228LH, V245EK, T286A, V292I, I293V, S322T, I326VCRF02_AG
 R215ZZR215FJ931368AZT, 3TCEFVM41L, D67N, K70R, V75VL, M184V, L210W, T215F, K219EK101E, V108I, Y181C, G190AV35IT, E36D, T39TA, K43Q, V60I, D123E, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, L228H, P243H, V245E, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
 R224ZZR224FJ931383D4T, 3TCEFV, NVPD67DN, K70R, M184V, K219KQK101E, K103NS, G190AE28EK, V35T, V60I, K122E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, K201KRT, Q207K, R211A, V245K, T286A, V292I, I293V, P294T, S322A, I326VCRF02_AG
 R469ZZR469FJ931393D4T, 3TCNVPM41L, D67DG, T69TADN, M184V, T215YK101E, V108I, Y181C, G190AE28R, K32E, V35T, E36D, E44ED, K49R, E53D, V60VI, V90I, L109I, I135V, S162A, K173T, Q174E, D177E, I178IM, T200A, E203ED, Q207EK, H208HY, R211K, W212WR, H221HY, V245K, A272P, K281R, T286A, E291D, V292I, I293V, E297Q, S322T, I326VCRF02_AG
 R268ZZR268FJ931444AZT, 3TCNVPM184VK101E, G190AK11A, V35T, E36A, T39K, K43E, D123N, E138EA, I142V, S162AT, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207K, R211N, V245E, D250E, S251H, K281R, T286A, E291D, V292I, I293V, P294T, P313S, V317G, S322T, I326VCRF02_AG
 R444ZZR444FJ931455D4T, 3TCNVPA62V, V75IT, M184VK101E, G190AI31L, V35T, E36D, T39N, E53D, D123E, I132IV, E138A, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291ED, I293V, P294PT, S322TCRF02_AG
 R447ZZR447FJ931457AZT, 3TCNVPM184V, T215YA98AG, K101E, G190AE6N, E28K, K32E, V35T, E36A, T39K, K43E, K64R, D123E, I135V, S162T, Q174T, D177E, T200A, Q207E, R211K, V245Q, E248N, A272P, K275R, V276T, L283I, T286A, E291ED, I293V, P294T, L295M, S322T, I326VCRF02_AG
 R450ZZR450FJ931460AZT, 3TCNVPM184VK101E, G190AE28K, K32E, V35T, T39K, A98AS, K122P, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, E248D, A272P, K275R, L279IM, T286A, E291D, V292I, I293V, P294T, K311KR, S322A, I326IVCRF02_AG
Germanaud (2010)55685568 AZT, 3TCNVPM184VK101E, Y181CK20R, K22N, V35T, E36D, T39M, K49R, V90I, I135T, S162A, P170L, R172K, K173A, Q174E, D177E, I178M, T200A, K201R, E204K, Q207E, R211KCRF02_AG
Charpentier (2011)CR-30CR-30FJ688236AZT, 3TCNNRTIK70R, M184V, K219KQA98G, K101E, Y181CE28K, V35T, T39L, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, L228R, V245Q, T286TA, E291D, V292I, I293V, P294T, S322ACRF02_AG
 CR-19CR-19FJ688225AZT, 3TCNNRTIM184V, L210W, T215YK101E, Y188LS3C, E28A, V35K, T39A, S48E, V60I, S68SG, A98S, I135T, S162A, Q174E, D177E, I178M, T200A, Q207D, P243T, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326VCRF02_AG
Dagnra (2011)08TG.T300808TG.T3008FR715252D4T, 3TCNVPK65R, T69~K101E, Y181C, G190SV35T, E36D, K43R, S162A, K173T, Q174E, D177E, T200A, Q207E, V245E, A272P, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, A376S, T377M, K390R, E432DCRF02_AG
 08TG.T302908TG.T3029FR715255D4T, 3TCNVPM184VK101E, G190AV35K, K122P, I135IT, S162A, E169D, K173A, Q174K, D177E, G196GE, T200A, Q207E, F214L, V245Q, A272P, T286V, E291D, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, K390R, K395R, A400AT, T403M, E432DCRF02_AG
 08TG.T304108TG.T3041FR715258D4T, 3TCNVPM184VK101E, G190AM16MK, I31IK, V35T, V60I, S68G, K122E, I135V, S162A, K173I, Q174K, D177E, T200A, Q207G, R211N, T286A, I293V, P294T, E312D, I326V, Q334M, G335D, M357R, G359T, V365I, T369V, A371V, I375V, A376V, T386TA, A400T, T403M, W410Y, E432DCRF02_AG
Fokam (2011)CIRCB-11835CIRCB-11835JQ796182AZT, 3TCNVPM184VK101E, G190AE28K, V35T, E36D, T39K, K43KE, K104R, K122E, D123DG, I142V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, F214L, V245L, T286A, E291D, I293V, S322A, I326VCRF02_AG
Mollan (2012)MK252MK252w75 TDF, FTCEFVK65RK101E, G190AP4S, V35T, E36D, V60I, K122E, D123E, I135R, S162Y, K173S, Q174K, D177E, V179I, T200A, Q207E, R211KCRF02_AG
Kebe (2013)SNA3-262SNA3-262HM002519NRTINVPM184VK101E, G190AE28EK, V35T, E36D, K49R, V60I, V90I, K102Q, K122Q, I135V, S162A, E169N, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, V245ECRF02_AG
 SNA3-175SNA3-175HM002529NRTINVPM41L, T215YK101E, Y181C, G190AV35T, E36D, K49R, T69N, V90I, L109I, K122E, I135V, T139K, S162A, E169D, K173A, Q174K, D177E, I178M, G196E, T200A, E203Q, Q207E, H208Y, R211K, L228R, V245E, E248DCRF02_AG
 SNA3-133SNA3-133HM002528NRTINVPM41L, T215YK101E, Y181C, G190AV35T, E36D, K49R, T69N, V90I, L109I, K122E, I135V, T139K, S162A, E169D, K173A, Q174K, D177E, I178M, G196E, T200A, E203Q, Q207E, H208Y, R211K, L228R, V245E, E248DCRF02_AG
 SNA3-139SNA3-139JN193500NRTINVPM184VA98AG, K101E, V108I, G190AV35T, E36D, V60I, K102Q, V106I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207ECRF02_AG
 SNA3-196SNA3-196JN193494AZT, 3TCNVPM184VK101E, G190AV21I, V35T, T39A, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207R, R211ECRF02_AG
 SNA3-364SNA3-364JN193501AZT, 3TCNVPM41ML, M184V, T215TFISA98G, K101E, V108VI, Y181CS3SI, I5IM, V21VI, V35T, E36ED, I37IF, T39TA, K49R, P52PFLS, V60I, D121DE, K122E, D123N, I135V, I142V, S162T, E169E*, K173KT, D177E, I178M, Q207A, R211K, L228RCRF02_AG
 SNA3-195SNA3-195HM002541AZT, 3TCNVPM184VK101E, G190AV21I, V35T, T39A, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207R, R211E, V245Q, A272P, K275R, K281R, L283I, E291D, I293V, P294T, E297EK, S322TCRF02_AG
 SNA3-302SNA3-302HM002520NRTINVPM184VK101E, G190AV35T, E36D, T39A, K49R, V60I, S68G, K122E, I135R, S162A, K173R, Q174K, D177E, I178M, T200A, Q207G, R211K, V245Q, E248DCRF02_AG
 SNA3-188SNA3-188HM002531NRTINVPM41L, D67N, L74I, V75M, M184V, L210W, T215Y, K219NA98G, K101E, G190SK22R, V35T, T39A, E44D, V118I, K122E, D123N, S162T, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272PCRF02_AG
Nii-Trebi (2013)775775AB751454D4T, 3TCEFVM184VK101E, V108I, G190SK13KN, V35T, E36D, K49R, V106VI, K122P, I135V, S162A, T165I, E169D, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, V245QCRF02_AG
Pircher (2013)B1125B1125JX110225D4T, 3TC, AZTNVPL74I, M184V, T215FY, K219KNA98G, K101E, V108I, M230LK22R, V35T, T39L, S68G, K104R, K122E, D123S, E138A, S162A, Q174K, T200A, E203D, Q207D, H221Y, V245QCRF02_AG
Rawizza (2013)PJ0771PJ0771KF241503NRTINNRTIM184VK101E, G190AK11A, V35T, E36A, T39K, K43E, V60VI, K122KE, D123N, E138A, I142V, S162T, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207K, R211N, V245E, D250E, S251H, K281R, T286A, E291D, V292I, I293V, P294T, P313S, V317EG, S322T, I326VCRF02_AG
Thiam (2013)2667-HALD2667-HALDJN673611NRTINNRTIM41L, D67N, K70R, M184V, T215F, K219QK101E, G190AV35T, T39A, V60VI, D121DN, K122PQ, I135L, E138Q, S162A, K173T, Q174K, D177EK, I178L, T200A, I202IV, Q207E, R211K, P243A, V245K, A272P, V292I, I293V, P294T, K311KR, S322T, I326VCRF02_AG