<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 19
Isolates 19
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patPIA01_PIA731AJ577973AZT, DDI, 3TC, D4T, ABCNVP, EFVM41L, L74V, M184V, L210W, T215YL100I, K103NT27P, V35T, E36A, K122E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, H221YCRF02_AG
Non-B Workgroup (2005)TK2003TK2003a AZT, 3TC, DDI, ABCEFVL74V, M184VL100I, K103NE6D, V35I, V60I, S68G, T139K, S162A, K173T, Q174K, D177E, I178V, V179I, G196E, T200A, Q207E, P243T, V245Q, T286A, E291D, I293V, P294T, G316E, S322A, I326VCRF02_AG
Toni (2005)IC03nvp2IC03nvp2DQ056375NoneNVP L100IK32R, V35T, V90G, D123E, I135V, K173T, Q174K, D177E, T200A, Q207E, R211KCRF02_AG
Seyler (2007)599CS_599 D4T, DDIEFV L100I, K103NE28EK, V35T, E36D, V60I, K101KQ, K122E, I135V, S162A, K173T, Q174K, D177E, Q207E, R211K, L228R, V245Q, E248N, S251VCRF02_AG
Charpentier (2011)CR-34CR-34FJ688240AZT, 3TCNNRTIM41L, L74V, T215YL100I, K103NE6EK, V35T, T39TA, K43KN, E44ED, K49R, V118I, K122P, S162DN, K173T, Q174K, D177E, T200A, Q207E, P243PA, V245T, E248ED, S251SN, T286A, E291D, V292I, I293V, P294T, S322ACRF02_AG
Mollan (2012)MK26MK26w62 ABC, 3TCEFVL74LV, M184VL100I, K103NV35T, T39M, I135T, I142V, S162A, K173T, Q174K, T200A, Q207E, R211K, H221Y, V245E, E248A, K281R, T286A, E291D, V292I, I293VCRF02_AG
Ugbena (2012)2-0412-2-041 TDF, FTCNVPK65R, M184VL100I, K103NV35T, E36D, V60I, D123E, I135T, S162A, Q174E, V179I, T200A, I202V, Q207D, V245QCRF02_AG
Etiebet (2013)10283807NG.SN237HQ843616TDF, FTCEFVK65R, M184V, K219KEL100I, K103NI2IM, V35T, T39L, V60I, D123N, D177E, I178F, Q197L, T200Q, Q207E, R211KCRF02_AG
 15105007NG.SN339HQ843544TDF, FTCEFVK65R, M184IL100I, K103NV35T, E36A, T39A, K43E, K49R, S68G, V90VI, T139K, S162A, E169D, Q174K, N175Y, D177E, T200A, Q207D, R211KCRF02_AG
Theys (2013)2355223552KC220198TDF, 3TCEFVD67N, K70R, L74I, M184V, T215F, K219QL100I, K103N, V179VEGK64KR, E138Q, S162A, K166KR, K173T, Q174R, D177E, I178IM, G196GE, T200A, E203EK, Q207E, F214L, L228HCRF02_AG
 2574025740KC220373NRTI, TDFNNRTIK65KR, M184VL100I, K103NK122A, I135T, S162A, Q174N, D177E, I195L, T200A, Q207E, R211KCRF02_AG
 2141821418KC220075NRTI, TDFNNRTIM184MIVL100I, K103NV60I, D123E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211RKCRF02_AG
 2203422034KC220119NRTI, TDFNNRTIM41L, L74V, L210W, T215YA98G, L100I, K103NL109I, K122E, S162A, K173T, Q174R, D177E, T200E, E203K, Q207E, R211K, L228RCRF02_AG
Thiam (2013)SN249HALDSN249HALDJX187616NRTINNRTID67N, K70GR, M184I, T215Y, K219QL100I, K103NV35T, E36D, K49R, V60I, I135V, T139K, S162A, T165L, K173T, Q174K, D177E, I178M, T200A, Q207E, H208Y, R211K, V245Q, E248NCRF02_AG
Jenabian (2015)DR27DR27KF735833NRTINNRTIK65R, L74IV, Y115F, M184VL100I, K103NE6ED, V35T, T39S, K102R, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, K311Q, S322T, I326VCRF02_AG
Yang (2015)3611536115KY213828TDF, 3TCEFVA62V, K65R, M184V, K219NL100I, K103NV35T, T39D, S68N, K122E, D123S, S162A, F171L, R172G, K173Q, Q174K, D177EG, T200A, Q207K, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, L295MCRF02_AG
Chaplin (2017)NJIH0080NJIH0080MF622631NRTINNRTIK65R, V75M, M184VL100I, K103NE36D, V90VI, K102Q, K122E, D123E, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, V245Q, E248NCRF02_AG
 NJIH0079NJIH0079MF622630NRTINNRTIK65R, M184VL100I, K103N, V108VIE36D, V90I, K102Q, K122E, D123E, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, V245Q, E248N, T286A, E291D, V292I, I293V, P294V, S322A, G335DCRF02_AG
Rhee (2017)EJ002060EJ002060KY190985TDF, FTCEFVM184I, K219KNL100I, K103NV35T, E36D, V60I, I135V, S162A, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, R211RKCRF02_AG