<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation A98S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 27
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_501TH_501AY9018623TC, D4TEFVD67N, V75M, M184V, T215FK103N, Y181I, G190AL34I, V35T, T39K, K43E, A98S, K122E, D123S, K173I, Q174K, D177E, T200R, Q207A, R211S, K238R, V245ECRF01_AE
Nyombi (2008)TBK032TBK032EU251734NoneNVP  V35T, T39TR, A98S, K104R, K122E, D123G, K173R, D177E, V179I, I202V, Q207A, V245Q, E248D, A272P, K275Q, K277R, K281R, E291D, I293V, V317A, G335D, F346Y, R356K, M357I, G359T, K366R, A376T, T377LCRF01_AE
Manosuthi (2010)250882250882 D4T, 3TCNVP Y181VK43E, T69N, A98S, K102R, K122E, D123S, S162A, K173T, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 25-027325-0273 D4T, 3TCNVPM41L, V75I, M184V, T215YV108I, Y181CV60I, S68G, A98S, K122E, D123S, I135V, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, L210S, R211S, H221Y, D237N, V245ECRF01_AE
 25-070025-0700 D4T, 3TCNVPK65R, F116Y, Q151MK103N, Y181CT39K, V60I, K64R, S68G, A98S, K122E, D123S, P170L, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
Puthanakit (2010)CR2534CR2534 D4T, 3TCNVPM184VY181CV35T, T39K, K43E, K49R, T69N, A98S, K101R, K122E, D123N, I135T, R172K, K173I, Q174K, D177E, I178L, T200A, Q207A, R211K, V245ECRF01_AE
Bunupuradah (2011)079-011-016079-011-016 D4T, 3TCEFV, NVPM184V, T215FK101E, V106M, G190AV35T, T39K, K43A, V60I, A98S, K122E, D123S, I135R, K173I, Q174K, D177E, I178M, T200A, Q207A, V245ECRF01_AE
 079-004-012079-004-012 D4T, 3TCNVPT69~, Q151M, M184I, K219RV108I, Y181CV35T, E36K, T39E, K65Q, S68~, V90I, A98S, K122E, D123N, I132L, I142V, K173A, Q174K, D177E, I178M, T200I, I202V, Q207A, R211S, F214L, V245ECRF01_AE
 079-011-019079-011-019 D4T, 3TCNVPM41L, A62V, V75I, M184V, T215YY181CI31L, V35M, T39K, K43E, E44A, A98S, V118I, K122E, D123S, I135R, K173L, Q174K, V179I, I202V, Q207A, R211S, H221Y, V245ECRF01_AE
 079-008-005079-008-005 D4T, 3TCNVP, EFVM184IK103NK20R, I31L, V35T, T39K, K43E, V90I, A98S, K122E, D123S, T165I, K173T, Q174K, D177E, T200A, I202V, Q207A, R211S, H221Y, V245E, L264QCRF01_AE
 079-005-017079-005-017 D4T, 3TCNVPM41L, D67N, M184V, L210W, T215FV108I, Y181CV35T, T39K, K43E, A98S, K122E, D123S, K173T, Q174K, D177E, I178M, V179T, G196E, T200A, Q207A, R211S, H221Y, K238R, T240K, V245ECRF01_AE
 079-010-041079-010-041 D4T, 3TC, AZTNVPD67N, K70R, M184V, T215Y, K219QY181VK20R, V35T, T39K, K43E, A98S, K122E, D123S, K173V, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 079-011-038079-011-038 D4T, 3TCNVPM184VY181VK32E, V35T, T39K, A98S, K122E, D123S, I135K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, L228R, K238R, V245ECRF01_AE
Ferradini (2011)180194RTHM026321AZT, 3TCNVPM41L, M184V, T215FK103NV35T, T39K, K43E, S68G, A98S, K122E, D123S, E138Q, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
Ngo-Giang-Huong (2011)PHPT0296PHPT0296RTHQ9964173TC, DDINVPL74LV, V75VI, M184VY181CV35T, T39K, K43E, K49R, A98S, K101R, K122E, D123S, I135T, S162SN, Q174R, D177E, I178M, T200A, Q207A, R211S, K238RCRF01_AE
 PHPT4810PHPT4810RTHQ996491D4T, 3TCNVPM184VK103NV35T, T39K, K43E, V60I, S68G, A98S, K122E, D123K, I135T, K173L, Q174K, D177E, I178M, Q197P, T200A, Q207A, R211S, H221HYCRF01_AE
Nouhin (2013)S0305291S0305291KF292520NRTINNRTIM184VG190A, M230LV35T, T39K, K43E, T69N, A98S, K102R, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207A, R211K, K238RCRF01_AE
 U0720072U0720072KF292803NRTINNRTI V106A, F227LV35T, T39K, E40Q, K43E, K49R, S68G, A98S, K122E, D123S, S162N, K173I, Q174K, D177E, T200E, Q207D, R211K, K238RCRF01_AE
 S1124280S1124280KF292599NRTINNRTIK70KR, M184VY181CV35T, T39K, T69N, A98S, G112A, K122E, D123S, K173L, Q174K, D177E, T200I, Q207A, R211N, L228R, K238KRCRF01_AE
 S1128134S1128134KF292598NRTINNRTID67N, K70R, M184V, K219QK103N, K238TE28A, V35T, T39E, V60I, T69TN, A98S, K122E, D123S, I135T, S162Y, K173T, Q174K, D177E, T200A, E203D, Q207A, R211RS, L228HCRF01_AE
 S1119271S1119271KF292626NRTINNRTID67N, K70R, M184V, K219EY181CV35T, T39K, K43E, K49R, V60I, A98S, K101Q, Y115S, F116V, V118S, P119S, K122E, D123S, R125K, Q145H, Y146C, L149LI, K173I, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 U1213135U1213135KF292827NRTINNRTIM41L, L74I, M184V, T215YK103NK20R, K32KI, V35K, E36ED, T39D, A98S, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, E203D, Q207A, L210LS, H221Y, K238SCRF01_AE
 T0904064T0904064KF292690NRTINNRTIM184V, L210W, T215Y, K219NY181CE28K, V35T, T39E, A98S, K101Q, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200K, Q207A, R211SCRF01_AE
 Q0817107Q0817107KF292427NRTINNRTIM41L, M184V, T215FK103NV35T, T39K, K43E, S68G, A98S, K122E, D123S, E138Q, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
 S1124162S1124162KF292606NRTINNRTIK65KN, V75M, F77L, F116FY, Q151M, M184VK103N, V108VI, P225HV35T, T39N, S68SG, V90I, A98S, K102KR, K122E, D123S, A158T, S162A, T165L, K173R, Q174K, N175Y, D177E, T200K, K201I, Q207V, R211N, F214L, L228R, K238RCRF01_AE
Nerrienet (2014)S1119066S1119066JN675857NRTINNRTIV75M V35T, T39K, K43E, K82KR, A98S, V118I, K122E, D123S, A158S, K173A, Q174K, D177E, I178M, V179I, Q207A, R211S, K238RCRF01_AE
 S0108225S0108225JN675891NRTINNRTIM41L, L74V, M184V, L210W, T215YK103N, G190AK32KE, V35T, T39K, K43A, E44D, S68G, A98S, V118I, K122E, D123S, I135T, T165L, K173T, Q174K, N175NY, D177E, T200A, Q207A, R211NS, D218ECRF01_AE