<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation V90I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 67
Isolates 68
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Hsu (2005)BAA154763BAA154763AY870164D4T, DDI, AZT, 3TCEFVM41L, D67N, M184V, T215YY188LS3SG, E6D, V35M, T39K, K43E, E44EA, K64R, V90I, K122E, D123S, I135T, K173T, Q174K, N175NY, D177E, T200A, Q207A, D218E, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, R358RG, G359S, K366R, T369AV, A371V, A376T, K390R, K395RCRF01_AE
 BAA161447BAA161447AY870240D4T, DDI, AZT, 3TCNVP, EFVM41L, D67N, T69D, L210W, T215FK101E, Y188LE6D, E28K, K32E, V35I, T39E, V60I, V90I, V106L, V118I, K122E, D123S, I135T, R172K, K173I, Q174K, D177E, I178L, V189I, G196E, E203K, Q207A, R211N, K223KQ, K238R, V245E, K275R, T286A, E291D, I293V, E312T, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, A376C, K390R, K395RCRF01_AE
Non-B Workgroup (2005)TH_168TH_168AY605582AZT, DDINNRTID67N, K70R, T215YG190AL34I, V35T, T39K, K43E, V90I, T107P, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, G196E, T200A, E203D, Q207A, R211S, V245ECRF01_AE
 TH_527TH_527AY901869D4T, 3TCNVPM41L, D67N, K70R, L74I, M184I, T215F, K219QA98G, K101E, G190AV35T, T39K, K43E, V60I, V90I, K122E, D123S, I135L, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245E, D250YCRF01_AE
 TH_720TH_720AY901937D4T, 3TCNVPA62V, D67N, K70E, V75T, Q151MK101E, V108I, Y181C, G190AA33V, V35T, T39K, E40K, K43E, V90I, V118C, K122E, D123S, K166R, Q174N, D177E, I178M, S191C, T200I, Q207D, L228H, K238R, V245ECRF01_AE
 TH_790TH_790 D4T, 3TCNVPM184IY181CV35T, T39K, K43E, V90I, K122E, D123S, I135T, I142V, R172K, K173M, Q174K, D177E, I178M, E194D, T200A, Q207A, R211S, K238R, V245ECRF01_AE
Baxter (2006)48-41434143-30408DQ878375NRTINNRTIM41L, D67N, T69D, K70R, V75M, T215F, K219Q E6N, K11T, V35T, E36A, T39K, K43E, V60I, V90I, K122E, D123NS, I135V, I142V, S162H, K173S, D177E, V179I, I202V, Q207A, L228H, V245Q, E248D, D250DE, A272P, T286A, E291D, V292VI, I293V, P294T, E312D, G335D, M357K, G359S, K366R, T369V, E370D, A371V, I375V, A376V, T377M, T386ACRF01_AE
Tee (2006)MYKL143903MYKL1439AY960886AZT, 3TCEFV K103N, Y181C, P225HK20R, V35T, T39N, V90I, K122E, D123S, K166R, K173I, Q174K, I178L, E194A, T200I, Q207A, R211S, L228R, K238R, V245ECRF01_AE
Zhong (2007)D008405CN_084EF199612NRTINVPK65RV179D, G190A, K238TE6D, K11A, V35T, T39K, K43E, S68G, V90I, K122E, D123S, I135T, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
Manosuthi (2010)250833250833 D4T, 3TCNVPD67G, M184VY181CT39K, K43E, S68G, V90I, V106I, K122E, D123S, T139Q, I142L, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, L246SCRF01_AE
 25N009925N0099 D4T, 3TCNVPK65R, K70W, Q151M, K219RK103N, Y181C, G190AT39K, K43E, V60I, S68G, T69K, V90I, K122E, D123N, I135L, P157A, R172K, Q174K, D177E, I178M, T200A, Q207A, R211S, K238ICRF01_AE
 250888250888 D4T, 3TCNVPY115F, F116Y, Q151M, M184VK103S, G190AT39K, K43E, S68G, V90I, K122E, D123S, I135T, T165I, R172K, K173I, Q174K, D177E, I178M, G196E, T200IM, Q207A, R211S, L228R, V245ECRF01_AE
 25-067725-0677 D4T, 3TCNVPK65R, V75M, F77L, F116Y, Q151MK103N, Y181CT39K, K43E, S68G, T69I, V90I, K101R, V118I, K122E, D123N, P157A, K173V, Q174K, I178M, Q207A, R211S, F214L, K223Q, V245ECRF01_AE
 25-065225-0652 D4T, 3TCNVP  T39K, K43E, V90I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, I244V, V245ECRF01_AE
 250821250821 D4T, 3TCNVPM184VV108I, G190AT39K, K43E, V90I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 250851250851 D4T, 3TCNVPK70R, V75I, M184V, K219EV108I, Y181CT39K, K43E, T69N, V90I, K122E, D123S, I132L, S162Y, K166R, K173I, Q174K, D177E, V189I, I202V, Q207A, R211N, H221Y, K238R, V245QCRF01_AE
 250873250873 D4T, 3TCNVPD67G, K70R, L74I, M184V, T215F, K219EV108I, Y181CT39E, V60I, S68G, W88C, V90I, V106I, K122E, D123S, I135T, S162Y, P170S, K173IT, Q174K, D177E, Q207A, R211N, H221Y, K238R, V245ECRF01_AE
Puthanakit (2010)PHPT129PHPT129 D4T, 3TCNVPM184VK101E, G190AQ23QL, V35T, T39K, K43Q, V60I, S68G, V90I, V106I, K122E, D123S, I135T, T165I, Q174E, I178M, Q207A, R211SCRF01_AE
 CR3767CR3767 D4T, 3TCNVPM41L, V75M, M184V, T215FY181CK32I, V35T, T39K, K43A, K49R, V60L, V90I, K122E, D123S, I135V, S162D, K166R, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, F214L, K238R, V245ECRF01_AE
Zolfo (2010)A13412A 13412 M18HM565575D4T, 3TCNVPM184V, K219NY181CT39E, S68K, V90I, K122E, D123S, I135R, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
  A 13412 M24HM565536D4T, 3TCNVPM184V, K219NY181CT39E, S68K, V90I, K122E, D123S, I135R, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
Bunupuradah (2011)079-003-004079-003-004 D4T, 3TCNVPM184V, T215FK103N, Y181CV35T, T39K, K43E, V90I, K101R, K122E, D123S, S162F, E169Q, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 079-010-001079-010-001 D4T, 3TCNVPV75M, M184V, L210LW, T215FY181CK32R, V35T, T39K, K43E, V90I, K122E, D123S, I135T, S162Y, K173I, Q174K, D177E, I178M, R211S, Y232H, K238R, V245E, V261LCRF01_AE
 079-010-019079-010-019 D4T, 3TCNVP, EFVM184IA98G, K101E, Y181C, G190AV35T, T39K, K43E, S68G, V90I, K122E, D123N, I135T, S162A, T165L, K173T, Q174K, D177E, I178M, Q207A, R211S, F214L, V245ECRF01_AE
 079-011-010079-011-010 D4T, 3TCNVPM184VY181CV35T, T39K, K43E, S68G, V90I, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, L193F, Q207A, R211S, K238R, V245ECRF01_AE
 079-004-012079-004-012 D4T, 3TCNVPT69~, Q151M, M184I, K219RV108I, Y181CV35T, E36K, T39E, K65Q, S68~, V90I, A98S, K122E, D123N, I132L, I142V, K173A, Q174K, D177E, I178M, T200I, I202V, Q207A, R211S, F214L, V245ECRF01_AE
 079-010-027079-010-027 D4T, 3TCNVPA62V, K65N, D67N, K70T, V75M, K219RV106AK20R, A33V, V35R, E36D, T39K, K43E, K49R, S68R, T69N, V90I, I94L, K101A, V118I, K122E, D123S, S162D, K173T, Q174K, D177E, I178M, V179I, T200A, I202V, E203D, Q207A, R211K, F214L, E224EG, K238R, Q242K, V245E, K249RCRF01_AE
 079-005-011079-005-011 D4T, 3TCNVPV75I, F77L, M184V, T215FY181CV35T, T39K, K43E, T58S, V90I, K122E, D123S, I135T, S162N, K173L, Q174K, D177E, T200E, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 079-008-005079-008-005 D4T, 3TCNVP, EFVM184IK103NK20R, I31L, V35T, T39K, K43E, V90I, A98S, K122E, D123S, T165I, K173T, Q174K, D177E, T200A, I202V, Q207A, R211S, H221Y, V245E, L264QCRF01_AE
 079-011-027079-011-027 D4T, 3TC, AZT, ABC, DDINVPK70E, V75I, Y115F, M184VY181CI31L, V35T, T39K, K43E, T69N, V90I, K122E, D123N, S162Y, K173M, Q174K, V179I, T200A, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 079-011-029079-011-029 ABC, 3TC, DDIEFVL74V, Y115F, M184VV106A, V179D, P225HV35T, T39K, K43E, S68G, V90I, K103R, V111I, K122E, D123N, S162A, K173I, Q174K, D177E, T200A, Q207A, R211N, V245ECRF01_AE
 079-003-049079-003-049 D4T, 3TC, AZTNVPD67N, K70R, M184VY181CK20R, V35T, T39K, K43E, K49R, V60I, V90I, K122E, D123S, S162D, E169A, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, H221Y, K238R, V245QCRF01_AE
 pt001pt001 3TC, D4TNVPM41L, V75M, M184V, T215FK101E, V108I, Y181VV35T, T39K, K43E, T69N, V90I, L109I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, D218E, K238R, V245ECRF01_AE
 079-007-026079-007-026 D4T, 3TCNVPM184VK103S, G190AE28A, V35T, T39K, K43E, S68G, T69S, V90I, K122E, D123S, I135T, S162A, K173I, Q174K, D177E, I178M, V179I, T200R, Q207A, R211S, K238R, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT0069PHPT0069RTHQ996411D4T, 3TCNVPD67N, M184VY181CV35T, T39K, K43E, V90I, K122E, D123S, I135T, S162N, Q174K, D177E, Q207A, R211N, H221L, K238SCRF01_AE
 PHPT0111PHPT0111RTHQ996413D4T, 3TCNVPD67N, M184VY181C, G190AV35T, T39K, K43E, V90I, K122E, D123S, I135T, R172K, K173I, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
 PHPT3644PHPT3644RTHQ996455D4T, 3TCNVPM184VK103NV35T, T39K, K43E, V90I, V118VI, K122E, D123S, I135T, T139R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
 PHPT2049PHPT2049RTHQ996486TDF, 3TCNVPA62V, K65N, Y115F, M184VV108I, Y181CV35T, T39K, E40A, K43A, S68G, V90I, K102R, K122E, D123S, I135L, S162N, R172RK, K173I, Q174K, D177E, Q207A, R211SCRF01_AE
 PHPT1247PHPT1247RTHQ996492AZT, 3TCEFVM184VK103N, Y181C, P225HV35T, T39K, K43E, V90I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, L228R, K238RCRF01_AE
 PHPT4028PHPT4028PR-RTHQ996516AZT, 3TCNVPV75M, M184VV108I, Y181CE6D, V35T, T39K, K43E, K49R, S68G, V90I, D123E, S162SN, T165V, K173V, Q174K, D177E, V179I, T200A, Q207A, R211S, H221Y, K238R, V245E, K249R, T286A, E291D, I293V, E312T, I326V, I329VCRF01_AE
 PHPT2972PHPT2972PR-RTHQ996523TDF, FTCNVPK65R, K219RK101E, V179F, Y181CE6D, V8I, K11T, V35T, T39K, K43KE, T69S, V90I, K122E, D123N, I135T, E169D, K173I, Q174K, D177E, G196E, I202V, Q207A, R211S, H221HY, V245E, V276I, E291D, V292I, I293V, E297A, E312T, I326V, I329VCRF01_AE
Coetzer (2013)KH028KH028KC533606D4T, 3TCNVPD67DN, M184IVY181CV35T, T39N, V90I, K122E, D123N, I135M, T165L, K173I, Q174K, D177E, I178M, Q207E, R211SCRF01_AE
 KH015KH015KC533642D4T, 3TCNVPA62V, D67E, M184I, L210W, T215FY181CI31L, V35T, T39K, K43E, V90I, V111I, D121H, K122E, T128X, K173I, Q174K, D177E, I178L, V179I, Q207A, R211N, L228HCRF01_AE
Nouhin (2013)U0910064U0910064KF292815NRTINNRTID67N, M184MV, T215FK103S, G190A, K238TV35T, T39K, K43E, V60I, V90I, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211NSCRF01_AE
 T0811155T0811155KF292658NRTINNRTIK70R, M184V V35T, T39K, K43E, K66R, V90I, K122E, D123S, I135V, S162HN, K166R, K173I, Q174K, D177E, V179I, T200I, Q207ACRF01_AE
 S0222060S0222060KF292515NRTINNRTID67DN, M184IVY181CV35T, T39N, V90I, K122E, D123N, I135M, T165L, K173I, Q174K, D177E, I178M, Q207E, R211SCRF01_AE
 Q0818136Q0818136KF292405NRTINNRTIF116Y, Q151M, M184IY181CV35T, T39K, K43E, V90I, V111I, K122E, D123S, S162A, T165TI, K173T, Q174K, D177E, T200I, Q207A, R211K, F214L, V245ECRF01_AE
 Q1205112Q1205112KF292436NRTINNRTID67N, K70R, M184I, T215F, K219EK101E, Y181C, G190AE28K, V35T, T39N, V90I, V106I, D121H, K122E, D123S, S162F, K173I, Q174K, D177E, I178L, Q207A, R211S, K238RCRF01_AE
 T0922244T0922244KF292694NRTINNRTI K101KE, Y181CV35T, T39N, K64R, V90I, K122E, D123N, I135IL, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
 T0619193T0619193KF292640NRTINNRTID67N, V75M, M184MI, T215FK101P, K103NV35K, T39D, W88C, V90I, K122E, D123N, R125RK, I142IT, S162NY, K173I, Q174K, D177E, V179VI, Q207NS, R211S, K238RCRF01_AE
 U0906112U0906112KF292812NRTINNRTIM184VY181CI31L, V35IT, T39K, K43E, K49R, V90I, K122E, D123S, S162SC, K173I, Q174K, D177DE, T200A, Q207A, R211S, H221Y, K238RCRF01_AE
 T0825204T0825204KF292677NRTINNRTIK65R, K70T, V75M, M184IY181CI31L, V35T, T39K, S68N, V90I, K122E, T139TI, S162Y, K173I, Q174K, D177E, I178IM, V179I, T200I, Q207A, R211S, F214L, H221Y, K238RCRF01_AE
 P1228096P1228096KF292345NRTINNRTIA62V, D67G, V75I, F77L, F116Y, Q151M, M184I, K219EV108I, Y181CI31L, V35T, T39K, E40K, K43E, S68N, V90I, K122E, D123S, S162Y, R172K, K173I, Q174K, D177E, Q207A, R211S, F214L, K238RCRF01_AE
 T0811233T0811233KF292696NRTINNRTIV75M, M184VK103N, V108I, P225HV35T, T39K, K66R, S68G, V90I, K122E, D123N, S162N, T165IM, K173T, Q174K, D177E, I178M, E194KT, T200A, Q207A, R211N, E224EK, K238RCRF01_AE
 Q0314121Q0314121KF292357NRTINNRTIV75M, F77L, Q151M, M184VK103NI31L, A33V, V35T, T39A, T69N, V90I, L109I, K122E, D123S, S162Y, R172K, K173I, Q174K, I178L, Q207A, R211N, L228R, K238RCRF01_AE
 Q1123085Q1123085KF292431NRTINNRTID67N, K70R, M184V, T215Y, K219QY181CL34I, V35T, T39E, T69N, V90I, K122E, D123S, I135T, S162H, K173L, Q174K, D177E, V179I, T200A, Q207D, K238RCRF01_AE
 Q0505105Q0505105KF292383NRTINNRTIM41L, D67N, K70R, L74I, V75M, M184V, T215F, K219QK101E, V108VI, G190AV35K, T39D, V60L, V90I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, S191SC, Q207A, R211S, K238RCRF01_AE
 S0828085S0828085KF292582NRTINNRTIM41L, D67N, V75I, M184I, L210W, T215Y, K219NY181CV35T, T39K, K43Q, K49R, V60I, V90I, V118I, K122E, D123S, I132L, E138Q, K173A, Q174K, D177E, I178M, V179I, G196GE, T200A, Q207A, R211D, D218E, K238RCRF01_AE
 T0422139T0422139KF292630NRTINNRTIK65R, V75M, F77L, Q151M, M184IY181C, G190AA33V, V35T, T39K, S68G, V90I, K122E, D123S, A158AS, S162Y, T165I, K173T, Q174K, D177E, Q207A, R211S, F214L, L228RCRF01_AE
 U0106091U0106091KF292741NRTINNRTIK65R, V75I, F116Y, Q151MY181NV35T, T39E, V60I, S68G, K82R, V90I, V111I, K122E, D123S, I132L, R172K, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, F214LCRF01_AE
 S1229293S1229293KF292611NRTINNRTIM184VY181CI31L, V35T, E36D, T39K, K43E, K66KQ, V90I, K122E, D123S, I135T, S162H, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, L210S, R211S, K238RCRF01_AE
 S1124162S1124162KF292606NRTINNRTIK65KN, V75M, F77L, F116FY, Q151M, M184VK103N, V108VI, P225HV35T, T39N, S68SG, V90I, A98S, K102KR, K122E, D123S, A158T, S162A, T165L, K173R, Q174K, N175Y, D177E, T200K, K201I, Q207V, R211N, F214L, L228R, K238RCRF01_AE
 P0926044P0926044KF292342NRTINNRTIV75I, M184V, T215YY181IV35T, T39K, K43Q, K49R, V60I, V90I, K122E, D123S, I132L, I135T, S162N, T165I, K173I, Q174K, D177E, I178M, V179VI, T200A, Q207A, R211S, F214LCRF01_AE
 T0528166T0528166KF292636NRTINNRTID67G, V75M, F77L, Q151M, M184IY181CV35T, T39E, V90I, K122E, D123S, I132L, K173I, Q174K, D177E, T200A, Q207A, R211S, H221Y, K238QCRF01_AE
 T0908182T0908182KF292714NRTINNRTIM184V, T215YY181CK32I, V35T, T39N, S68G, V90I, K122E, D123S, I135R, S162Y, K173I, Q174K, D177E, V179I, T200A, Q207G, R211SCRF01_AE
Theys (2013)4082440824KC221210NRTI, TDFNNRTIA62V V90I, K122E, D123N, E138A, K173L, Q174K, Q207A, R211SCRF01_AE
 8189981899KC219027NRTI, TDFNNRTIA62V T39K, V90I, K122E, D123N, A158S, K173L, Q174K, D177E, I178L, Q207A, R211S, V245MCRF01_AE
Nerrienet (2014)U0519246U0519246JN675839NRTINNRTIA62V, K65R, V75I, F77L, Q151MA98G, Y181C, G190AV21I, V35T, S68G, D76DN, V90I, V106I, K122E, D123N, I142V, R172K, K173A, Q174K, D177E, I178L, Q207A, R211S, F214LCRF01_AE