<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K238T
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 30
Isolates 30
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_154TH_154AY605567AZT, 3TCEFVD67N, K70R, M184V, K219QK103N, V108I, K238TV35T, T39K, K43E, V60I, D121H, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E, K249RCRF01_AE
Tee (2006)MYKL139903MYKL1399AY960882NRTI, D4T, DDIEFVD67N, K70RK103N, K238TK20R, V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, H221Y, V245ECRF01_AE
 MYKL140203MYKL1402AY960883AZT, 3TCEFVM184VK103N, V108I, K238TK20R, T27P, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200M, Q207A, R211S, V245ECRF01_AE
Zhong (2007)D008405CN_084EF199612NRTINVPK65RV179D, G190A, K238TE6D, K11A, V35T, T39K, K43E, S68G, V90I, K122E, D123S, I135T, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
Manosuthi (2010)250852250852 D4T, 3TCNVPM184VK103N, K238TT39K, K43E, K122E, D123S, I142V, K173T, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 250806250806 D4T, 3TCNVPM184VK103N, K238TT39K, K43E, K102R, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 25-070925-0709 D4T, 3TCNVPM184V, T215FK103N, M230L, K238TT39K, K43E, K104R, K122E, D123S, I135L, R172K, K173L, Q174K, D177E, I178M, T200A, Q207A, R211S, K219T, L228RCRF01_AE
Bunupuradah (2011)079-003-001079-003-001 D4T, 3TC, AZTNVPA62V, K65R, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, K238TK20R, V35T, T39K, K43E, S68G, T69I, V111I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, I244V, V245ECRF01_AE
 079-003-006079-003-006 D4T, 3TCNVPM41L, M184V, L210W, T215YK103N, K238TV35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, E138Q, T165I, K173S, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 079-004-008079-004-008 D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215FK103N, K238TV35M, T39K, K43E, V118I, K122E, D123S, E138Q, S162C, K173A, Q174K, N175Y, Q207A, R211S, V245ECRF01_AE
 079-003-024079-003-024 D4T, 3TCNVPM184VK103N, K238TV35T, T39N, K122E, D123S, E138Q, K166R, K173I, Q174K, D177E, T200K, Q207A, R211S, V245ECRF01_AE
 079-008-015079-008-015 D4T, DDI, 3TC, AZTEFV, NVPD67N, K70R, M184V, T215F, K219EK101P, V179D, M230L, K238TE28K, V35T, T39K, K43E, K49R, V60I, T69N, K103R, V111I, K122E, D123N, I167V, Q174R, D177E, Q207A, R211S, I244V, V245ECRF01_AE
 079-003-054079-003-054 D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215YK103N, K238TV35T, T39K, K43E, E44D, V111I, K122E, D123S, I135L, E138G, K173I, Q174K, D177E, I178L, V179T, Q207A, R211N, V245ECRF01_AE
Aghokeng (2013)HJ3393HJ3393JX983031NRTINNRTIM184VK103N, V108I, K238TK11T, V35T, T39K, D76DE, D121H, K122E, D123G, I135T, T165L, K173R, Q174K, D177E, V179I, G196E, Q207A, R211S, F214L, V245Q, A272P, T286A, V292VI, I293V, E297R, E312D, G333E, Q334H, R356K, M357R, R358K, G359S, A360T, K366R, A371V, I375V, A376T, T377L, T386A, K390R, A400TCRF01_AE
Coetzer (2013)KH004KH004KC533601D4T, 3TCNVPD67N, M184VK103N, K238TV35T, T39K, K43E, V60I, K122E, D123S, I135T, E138Q, S162C, K173I, Q174K, D177E, V179VI, T200A, Q207A, R211SCRF01_AE
Nouhin (2013)U0910064U0910064KF292815NRTINNRTID67N, M184MV, T215FK103S, G190A, K238TV35T, T39K, K43E, V60I, V90I, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211NSCRF01_AE
 T1001102T1001102KF292698NRTINNRTIL74I, V75M, M184V, L210W, T215Y, K219NA98G, K103N, F227L, K238TK20I, K30I, V35A, I37F, T39E, M41V, I47L, T69N, I94L, I135M, K173T, Q174K, D177E, I178M, T200A, Q207A, R211N, L228P, M230ICRF01_AE
 S0222401S0222401KF292516NRTINNRTIL74V, M184VA98G, K103N, K238TV35T, T39N, K43R, G112A, K122E, D123S, K173I, Q174K, D177E, T200I, I202V, Q207A, R211SCRF01_AE
 S1128134S1128134KF292598NRTINNRTID67N, K70R, M184V, K219QK103N, K238TE28A, V35T, T39E, V60I, T69TN, A98S, K122E, D123S, I135T, S162Y, K173T, Q174K, D177E, T200A, E203D, Q207A, R211RS, L228HCRF01_AE
 Q0905106Q0905106KF292428NRTINNRTID67N, K70R, M184V, T215F, K219EK103N, K238TV35T, T39E, K101KR, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I202V, Q207A, R211SCRF01_AE
 S1016197S1016197KF292604NRTINNRTID67N, M184VK103N, K238TV35T, T39K, K43E, K122E, D123N, I135L, E138Q, S162C, K173I, Q174K, D177E, T200A, Q207A, R211SCRF01_AE
 S1027158S1027158KF292597NRTINNRTIV75M, M184VK101E, G190A, K238TV35T, T39E, K122E, D123S, I142T, K173R, Q174K, D177E, I178M, Q207G, R211S, D237DNCRF01_AE
 U0420125U0420125KF292774NRTINNRTID67E, M184VK103N, K238TE29A, K30S, K32Q, V35R, C38S, T39K, K43E, N57D, T58P, K66R, S68G, T69S, W71G, K122E, D123N, K173A, Q174K, D177E, I178L, V179I, T200A, E204Q, Q207A, R211RSCRF01_AE
 S1125239S1125239KF292592NRTINNRTID67N, M184VK103N, K238TV35T, T39K, K43E, V60I, K122E, D123S, I135T, E138Q, S162C, K173I, Q174K, D177E, V179VI, T200A, Q207A, R211SCRF01_AE
 R0116169R0116169KF292442NRTINNRTID67G, K70R, V75M, M184IV179E, Y181C, K238TV35T, T39E, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, T200I, Q207A, R211S, F214LCRF01_AE
 T1202120T1202120KF292723NRTINNRTIM41L, D67N, V75M, F77L, Q151M, M184V, T215YK101E, G190A, K238TW24WCG, V35I, T39N, V111I, K122E, D123S, E138Q, K166R, F171Y, K173R, Q174K, D177E, I178M, V179I, E203D, Q207D, F214L, T216TSCRF01_AE
 T0813323T0813323KF292661NRTINNRTID67N, K70R, M184V, K219QK103KN, Y181C, G190GA, K238TK32I, V35T, T39E, V60I, K64R, V106VI, K122E, D123S, I135R, K173A, Q174K, D177E, V179I, T200TA, Q207S, R211S, D218E, L228HCRF01_AE
Pircher (2013)B1113B1113JX110214D4T, 3TC, AZTNVPM41L, D67N, L74V, M184V, L210W, T215Y, K219KNK103N, M230L, K238TI2IV, E6D, K20R, E28K, K32E, V35T, E36ED, T39K, K43E, E44D, K49R, V60I, K64R, V111I, V118I, K122KE, D123DN, K173A, Q174K, Q207A, H208HY, R211RK, V245ECRF01_AE
Van Zyl (2013)1127347KC423998AZT, 3TCNVPM184VV108I, Y181C, K238TK11T, V35T, V118I, D123N, I135M, K173S, Q174K, D177E, I202V, Q207N, R211G, F214L, L228LR, V245Q, E248D, K259KNCRF01_AE
Nerrienet (2014)R0712188R0712188JN675818NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215Y, K219RK103N, P225H, K238TV35T, T39E, V60I, V111I, D121H, K122E, I135T, I142V, K173T, Q174K, D177E, I178IM, D192N, T200A, Q207A, R211NCRF01_AE