<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K238S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 19
Isolates 21
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Hsu (2005)BAA157681BAA157681AY870186AZT, 3TCEFVD67DN, M184V, T215Y, K219KNL100LI, K103N, V108VIE6D, K11T, K20KR, V35T, T39K, K43E, K122E, D123S, S163SC, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, L210F, R211S, K238S, V245E, K275KQ, K277KR, T286TA, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369V, A371V, K390R, K395RCRF01_AE
Non-B Workgroup (2005)TH_203TH_203AY6056073TC, D4TNVPA62V, M184VG190AG15F, M16V, D17A, V35I, K122E, D123S, I142V, K173I, Q174K, D177E, I178V, T200I, E203D, Q207A, R211S, K238S, V245ECRF01_AE
 TH_500TH_500AY901861D4T, 3TCEFVD67N, M184VK103NV35T, T39K, K43E, V60I, K122E, D123S, I135T, I142V, K173I, Q174K, D177E, I178M, T200L, Q207A, R211S, K238S, V245ECRF01_AE
Puthanakit (2010)CR1893CR1893 AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EK103NE28A, V35T, T39Q, M41I, E44I, G45S, K122E, D123S, I135T, K173T, Q174K, D177E, I178M, T200A, E203Q, Q207D, R211K, P236R, K238S, V245QCRF01_AE
Zolfo (2010)A14438A 14438 RSHM565595D4T, 3TCNVPM184VK103NT39N, K122E, D123S, I135T, S162C, K173ILR, Q174K, D177E, T200K, K201I, Q207A, R211S, K238S, V245KCRF01_AE
  A 14438 M18HM565522D4T, 3TCNVPM184VK103NT39N, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200K, K201I, Q207A, R211S, K238S, V245KCRF01_AE
  A 14438 M24HM565521D4T, 3TCNVPM184VK103NT39N, K122E, D123S, I135T, S162SC, K173IR, Q174K, D177E, T200K, K201I, Q207A, R211S, K238S, V245KCRF01_AE
Bunupuradah (2011)079-011-015079-011-015 D4T, 3TCNVPM184V, K219EY181CV35T, T39K, K122E, D123S, A158T, K173R, Q174K, D177E, I178M, T200A, Q207K, R211S, K238S, V245KCRF01_AE
 079-010-031079-010-031 D4T, 3TCNVPM184VK103NV35T, T39K, K43E, K122E, D123N, I135T, K173R, Q174K, D177E, I178M, T200E, Q207A, R211K, K238S, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT0069PHPT0069RTHQ996411D4T, 3TCNVPD67N, M184VY181CV35T, T39K, K43E, V90I, K122E, D123S, I135T, S162N, Q174K, D177E, Q207A, R211N, H221L, K238SCRF01_AE
 PHPT4163PHPT4163PR-RTHQ996517TDF, FTCEFVV75M, M184VK103NE6D, K11T, V35T, T39K, K43E, V111I, E138G, K173V, Q174K, D177E, I178L, V179IT, T200TI, I202V, Q207A, Y232H, K238S, V245E, K249R, S251C, T286A, E291D, P294PQ, E312NT, I326V, I329VCRF01_AE
Nouhin (2013)U0811092U0811092KF292805NRTINNRTIM184VK103NV35T, T39K, K43E, K122E, D123S, I135T, S162C, K173KI, Q174K, Q207A, R211S, K238SCRF01_AE
 S0813204S0813204KF292579NRTINNRTID67G, M184VY181CV35T, T39E, T69N, K122E, D123S, I132L, I135T, S162C, K173T, Q174K, D177E, V179I, E203D, Q207A, L210S, R211S, H221HY, K238SCRF01_AE
 T0717083T0717083KF292649NRTINNRTIM184VK103NK20R, V21I, V35T, T39K, K43E, V60I, T69TS, K122E, D123S, Q174R, D177E, I178M, E194D, Q207A, R211S, K238SCRF01_AE
 U1213135U1213135KF292827NRTINNRTIM41L, L74I, M184V, T215YK103NK20R, K32KI, V35K, E36ED, T39D, A98S, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, E203D, Q207A, L210LS, H221Y, K238SCRF01_AE
 Q0215131Q0215131KF292354NRTINNRTIM41L, D67N, M184V, L210W, T215YA98G, K103N, V108IK30E, I31X, V35T, I37R, T39E, E42K, K43R, E44G, G45GR, K46KE, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S, K238SCRF01_AE
 S0813191S0813191KF292678NRTINNRTID67DN, K70R, M184V, K219QK103N, P225HK20R, V35T, T39K, K43E, V60VI, K122E, D123S, K173IR, Q174K, D177E, I178M, Q207A, K238SCRF01_AE
 T0814215T0814215KF292664NRTINNRTID67N, M184V, T215Y, K219KRA98G, K103KN, V179E, Y188YHK20R, E28D, V35T, T39E, V60I, V111I, D123N, K173T, Q174K, D177E, I178L, T200A, Q207A, R211S, F214L, K223KE, K238SCRF01_AE
 R0411255R0411255KF292466NRTINNRTIM184V, T215FK103N, V108I, M230LV35T, T39E, V60I, S68G, K122E, D123S, I135T, S162C, K173V, Q174K, T200A, R206K, Q207A, R211S, K238SCRF01_AE
 Q0426186Q0426186KF292367NRTINNRTIM41L, D67N, L74V, M184V, T215YK103N, Y181CK20R, K22R, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S, K238SCRF01_AE
 Q0404197Q0404197KF292360NRTINNRTID67N, K70R, M184V, T215F, K219QK103NV35T, T39E, V60I, K122E, D123S, I135T, E138Q, S162T, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, D218E, K238SCRF01_AE