<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 24
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_710TH_710AY901934D4T, 3TCEFVM184VV179D, M230LV35T, T39K, K43E, K103R, V111I, D121H, K122E, D123S, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, I244V, V245ECRF01_AE
Manosuthi (2010)25-040825-0408 D4T, 3TCNVPM184V, L210WG190A, M230LT39N, V60I, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
 25N005425N0054 D4T, 3TCNVPM184VK103N, M230LK43E, V60I, K64R, K122E, D123S, K166R, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 25-070925-0709 D4T, 3TCNVPM184V, T215FK103N, M230L, K238TT39K, K43E, K104R, K122E, D123S, I135L, R172K, K173L, Q174K, D177E, I178M, T200A, Q207A, R211S, K219T, L228RCRF01_AE
 250752250752 D4T, 3TCNVPK70R, L74V, M184V, K219QA98G, K103N, P225H, M230LT39K, K43E, S68G, T69N, K122E, D123S, I135L, R172K, K173I, Q174K, D177E, I178M, T200A, E203K, Q207AT, R211KCRF01_AE
 143511143511 D4T, 3TCNVPM184V, L210W, T215YK103N, M230LT39E, E44D, K102R, K122E, D123S, I135T, I142T, K173I, Q174K, D177E, I178M, G196E, T200A, E203D, Q207A, R211AT, Q242K, V245ECRF01_AE
 250748250748 D4T, 3TCNVPM184VK103N, M230LT39K, K43E, K122E, D123S, E138A, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, H221Y, V245ECRF01_AE
 25-046325-0463 D4T, 3TCNVPM184V, T215YV108I, Y181C, M230LT39K, K43E, S68G, S117T, K122E, D123S, S162C, K173N, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
Zolfo (2010)A14683A 14683 M12HM565563D4T, 3TCNVPM184V, T215FK103N, M230LT39K, K43N, S68G, K101R, V106I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, V245ECRF01_AE
  A 14683 M18HM565496D4T, 3TCNVPM184V, T215FK103N, M230LT39K, K43N, S68G, K101KR, V106I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, V245ECRF01_AE
 A14652A 14652 M18HM565553D4T, 3TCNVPM184VY181C, M230LT39K, K43E, K122E, D123S, I135T, S162C, E169AD, K173A, Q174K, D177E, T200I, Q207A, R211S, H221Y, K238R, V245ECRF01_AE
Bunupuradah (2011)079-004-009079-004-009 D4T, 3TCNVPL74V, M184V, L210W, T215YK103N, P225H, M230LV35M, T39K, K43E, S68G, V118I, K122E, D123S, I135L, E138A, K173I, Q174K, Q207A, R211S, V245ECRF01_AE
 079-003-035079-003-035 D4T, 3TC, AZTEFVM184VK103N, P225H, M230LV35T, T39K, K43E, K122E, D123S, S162C, K173T, Q174R, D177E, I178L, T200A, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 079-008-015079-008-015 D4T, DDI, 3TC, AZTEFV, NVPD67N, K70R, M184V, T215F, K219EK101P, V179D, M230L, K238TE28K, V35T, T39K, K43E, K49R, V60I, T69N, K103R, V111I, K122E, D123N, I167V, Q174R, D177E, Q207A, R211S, I244V, V245ECRF01_AE
Ferradini (2011)130187RTHM026316AZT, 3TCNVPV75L, F77L, M184V, T215YK103N, M230LV35T, T39K, K43E, D86E, K122E, D123N, I135T, K173R, Q174K, I178M, T200A, Q207A, R211SCRF01_AE
 170113RTHM026320AZT, 3TCNVPM41L, D67N, K70R, V75I, M184V, T215F, K219EA98G, K103N, V108I, M230LV35T, T39K, K43E, W88S, K122E, D123N, Q174R, D177E, Q207A, R211S, K238RCRF01_AE
 190334RTHM026322AZT, 3TCEFVM41L, V75M, M184V, L210W, T215YK103N, V108I, M230LI31IM, V35T, T39E, V60I, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211N, K238RCRF01_AE
Ngo-Giang-Huong (2011)PHPT0879PHPT0879RTHQ996425D4T, 3TCEFVM184VK103N, M230LV35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, D192G, Q207A, R211S, K238RCRF01_AE
 PHPT3732PHPT3732RTHQ996461D4T, 3TCNVPM184VK103N, M230LV35T, T39K, K43E, K122E, D123N, S162T, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238RCRF01_AE
 PHPT4153PHPT4153RTHQ996477D4T, 3TCNVPM184VK103N, M230LI5M, E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, T200R, Q207A, R211SCRF01_AE
 PHPT2322PHPT2322RTHQ996488AZT, 3TCNVPM184V, T215F, K219KNG190A, M230LV35T, T39A, V60I, W88C, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, K238RCRF01_AE
 PHPT1020PHPT1020RTHQ996497AZT, 3TCEFVM184V, L210W, T215YK103N, M230LT39K, K43E, E44ED, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, I178L, T200I, Q207A, R211NS, L228RCRF01_AE
 PHPT1216PHPT1216PR-RTHQ996502D4T, 3TCNVPM41L, L74V, M184V, T215FK103N, M230LK20R, V35T, T39K, K43E, V60I, K122E, D123S, K173R, Q174K, D177DE, I178M, G196E, T200I, Q207A, R211S, V245E, T286A, A288T, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
Reynolds (2012)F0293F0293-1JN652188D4T, 3TCNVPM184V, T215FG190A, M230LV35T, V60I, K122E, D123NS, K173A, Q174K, D177E, V179I, T200A, Q207AD, R211K, V245Q, D250E, A272S, T286A, E291D, V292I, I293VCRF01_AE
Coetzer (2013)KH031KH031KC533594D4T, 3TCNVPM184VK103N, M230LV35T, T39E, V106I, D121H, K122E, D123S, I135L, S162C, K173I, Q174K, D177E, Q207A, R211S, H221Y, K238RCRF01_AE

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