<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 13
Patients 49
Isolates 50
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_710TH_710AY901934D4T, 3TCEFVM184VV179D, M230LV35T, T39K, K43E, K103R, V111I, D121H, K122E, D123S, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, I244V, V245ECRF01_AE
Manosuthi (2010)25-040825-0408 D4T, 3TCNVPM184V, L210WG190A, M230LT39N, V60I, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
 25N005425N0054 D4T, 3TCNVPM184VK103N, M230LK43E, V60I, K64R, K122E, D123S, K166R, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 25-070925-0709 D4T, 3TCNVPM184V, T215FK103N, M230L, K238TT39K, K43E, K104R, K122E, D123S, I135L, R172K, K173L, Q174K, D177E, I178M, T200A, Q207A, R211S, K219T, L228RCRF01_AE
 250752250752 D4T, 3TCNVPK70R, L74V, M184V, K219QA98G, K103N, P225H, M230LT39K, K43E, S68G, T69N, K122E, D123S, I135L, R172K, K173I, Q174K, D177E, I178M, T200A, E203K, Q207AT, R211KCRF01_AE
 143511143511 D4T, 3TCNVPM184V, L210W, T215YK103N, M230LT39E, E44D, K102R, K122E, D123S, I135T, I142T, K173I, Q174K, D177E, I178M, G196E, T200A, E203D, Q207A, R211AT, Q242K, V245ECRF01_AE
 250748250748 D4T, 3TCNVPM184VK103N, M230LT39K, K43E, K122E, D123S, E138A, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, H221Y, V245ECRF01_AE
 25-046325-0463 D4T, 3TCNVPM184V, T215YV108I, Y181C, M230LT39K, K43E, S68G, S117T, K122E, D123S, S162C, K173N, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
Puthanakit (2010)CR3300CR3300 AZT, 3TCNVPD67N, K70R, V75I, M184V, T215I, K219EK101E, V108I, Y181C, M230LK20R, V35T, T39K, K43E, K122E, D123S, S162C, K173T, Q174K, D177E, T200A, I202V, Q207A, R211K, H221Y, V245ECRF01_AE
 PHPT037PHPT037 D4T, 3TC, AZTNVP, EFVM41L, V75M, F77L, M184V, L210W, T215F, K219NK103N, M230LV35T, T39K, K43E, E44A, K49R, V111I, K122E, D123S, K173T, Q174K, D177E, I178M, V179I, T200A, I202V, Q207A, H208HY, R211N, H221C, P225R, L228R, V245ECRF01_AE
 PHPT116PHPT116 D4T, 3TCNVPM184VK103T, M230LV35T, K122E, D123N, S162C, K173L, Q174K, D177E, I178L, T200A, Q207E, H221HY, K238RCRF01_AE
 PHPT143PHPT143 D4T, 3TCEFVM184V, T215YK103N, V108I, M230L, L234LIV35T, T39E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, V189I, T200K, Q207T, R211S, H221HY, K238RCRF01_AE
Zolfo (2010)A14683A 14683 M12HM565563D4T, 3TCNVPM184V, T215FK103N, M230LT39K, K43N, S68G, K101R, V106I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, V245ECRF01_AE
  A 14683 M18HM565496D4T, 3TCNVPM184V, T215FK103N, M230LT39K, K43N, S68G, K101KR, V106I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, V245ECRF01_AE
 A14652A 14652 M18HM565553D4T, 3TCNVPM184VY181C, M230LT39K, K43E, K122E, D123S, I135T, S162C, E169AD, K173A, Q174K, D177E, T200I, Q207A, R211S, H221Y, K238R, V245ECRF01_AE
Bunupuradah (2011)079-004-009079-004-009 D4T, 3TCNVPL74V, M184V, L210W, T215YK103N, P225H, M230LV35M, T39K, K43E, S68G, V118I, K122E, D123S, I135L, E138A, K173I, Q174K, Q207A, R211S, V245ECRF01_AE
 079-005-028079-005-028 3TC, D4TNVPD67N, M184V, L210W, T215YK103N, V108I, M230LV35T, T39K, K43E, K49R, K102G, K122E, D123S, S163C, I167V, E169D, K173I, Q174K, D177E, I178M, G196E, T200A, Q207A, R211S, V245ECRF01_AE
 079-003-035079-003-035 D4T, 3TC, AZTEFVM184VK103N, P225H, M230LV35T, T39K, K43E, K122E, D123S, S162C, K173T, Q174R, D177E, I178L, T200A, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 079-008-015079-008-015 D4T, DDI, 3TC, AZTEFV, NVPD67N, K70R, M184V, T215F, K219EK101P, V179D, M230L, K238TE28K, V35T, T39K, K43E, K49R, V60I, T69N, K103R, V111I, K122E, D123N, I167V, Q174R, D177E, Q207A, R211S, I244V, V245ECRF01_AE
 079-005-033079-005-033 3TC, D4TNVPM184V, K219EY181C, M230LV35T, T39K, K43A, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, T200A, I202V, Q207A, H221Y, V245ECRF01_AE
Ferradini (2011)130187RTHM026316AZT, 3TCNVPV75L, F77L, M184V, T215YK103N, M230LV35T, T39K, K43E, D86E, K122E, D123N, I135T, K173R, Q174K, I178M, T200A, Q207A, R211SCRF01_AE
 170113RTHM026320AZT, 3TCNVPM41L, D67N, K70R, V75I, M184V, T215F, K219EA98G, K103N, V108I, M230LV35T, T39K, K43E, W88S, K122E, D123N, Q174R, D177E, Q207A, R211S, K238RCRF01_AE
 190334RTHM026322AZT, 3TCEFVM41L, V75M, M184V, L210W, T215YK103N, V108I, M230LI31IM, V35T, T39E, V60I, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211N, K238RCRF01_AE
Ngo-Giang-Huong (2011)PHPT0879PHPT0879RTHQ996425D4T, 3TCEFVM184VK103N, M230LV35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, D192G, Q207A, R211S, K238RCRF01_AE
 PHPT3732PHPT3732RTHQ996461D4T, 3TCNVPM184VK103N, M230LV35T, T39K, K43E, K122E, D123N, S162T, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238RCRF01_AE
 PHPT4153PHPT4153RTHQ996477D4T, 3TCNVPM184VK103N, M230LI5M, E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, T200R, Q207A, R211SCRF01_AE
 PHPT2322PHPT2322RTHQ996488AZT, 3TCNVPM184V, T215F, K219KNG190A, M230LV35T, T39A, V60I, W88C, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, K238RCRF01_AE
 PHPT1020PHPT1020RTHQ996497AZT, 3TCEFVM184V, L210W, T215YK103N, M230LT39K, K43E, E44ED, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, I178L, T200I, Q207A, R211NS, L228RCRF01_AE
 PHPT1216PHPT1216PR-RTHQ996502D4T, 3TCNVPM41L, L74V, M184V, T215FK103N, M230LK20R, V35T, T39K, K43E, V60I, K122E, D123S, K173R, Q174K, D177DE, I178M, G196E, T200I, Q207A, R211S, V245E, T286A, A288T, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
Reynolds (2012)F0293F0293-1JN652188D4T, 3TCNVPM184V, T215FG190A, M230LV35T, V60I, K122E, D123NS, K173A, Q174K, D177E, V179I, T200A, Q207AD, R211K, V245Q, D250E, A272S, T286A, E291D, V292I, I293VCRF01_AE
Coetzer (2013)KH031KH031KC533594D4T, 3TCNVPM184VK103N, M230LV35T, T39E, V106I, D121H, K122E, D123S, I135L, S162C, K173I, Q174K, D177E, Q207A, R211S, H221Y, K238RCRF01_AE
Nouhin (2013)S0529099S0529099KF292550NRTINNRTIV75VM, M184V, T215FK101H, V106M, M230LV35T, T39K, K43Q, K122E, D123NS, S162C, K173T, Q174K, D177E, I178M, V179I, T200TI, Q207A, R211N, D218E, L228HQ, K238RCRF01_AE
 S0305291S0305291KF292520NRTINNRTIM184VG190A, M230LV35T, T39K, K43E, T69N, A98S, K102R, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207A, R211K, K238RCRF01_AE
 Q0818133Q0818133KF292404NRTINNRTIV75M, M184V, L210W, T215FK103N, V108I, M230LV35T, T39K, K43E, V118I, D121DN, K122E, D123S, R125RK, R143RK, K173I, Q174K, D177EK, I178M, R199RK, T200I, R206RK, Q207E, R211K, D218N, K238RCRF01_AE
 S0822096S0822096KF292600NRTINNRTIM184V, T215FG190A, M230LV35T, T39E, E40D, K49R, V106I, K122E, D123S, I135T, S162C, K173T, Q174K, D177EK, S191SP, Q207A, R211S, K223T, L228R, K238RCRF01_AE
 Q1003147Q1003147KF292418NRTINNRTID67N, M184V, L210W, T215Y, K219NY181C, M230LV35T, T39E, E44D, V111I, K122E, D123S, E138G, K166R, K173I, Q174K, D177E, I178V, G196E, Q207K, R211N, H221Y, K238RCRF01_AE
 03-018703-0187KF292321NRTINNRTIV75L, F77L, M184V, T215YK103N, M230LV35T, T39K, K43E, D86E, K122E, D123N, I135T, K173R, Q174K, I178M, T200A, Q207A, R211SCRF01_AE
 Q0602098Q0602098KF292385NRTINNRTIM41L, D67N, K70R, V75I, M184V, T215F, K219EA98G, K103N, V108I, M230LV35T, T39K, K43E, W88S, K122E, D123N, Q174R, D177E, Q207A, R211S, K238RCRF01_AE
 T0630259T0630259KF292688NRTINNRTIM184V, T215FK103KN, M230LK22T, V35T, T39E, V106VI, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238RCRF01_AE
 Q0616198Q0616198KF292390NRTINNRTIT69D, V75M, M184V, L210W, T215FK103N, M230LV35T, T39E, E44D, V106I, V118I, K122E, D123S, I135T, S162CY, K173I, Q174K, D177E, Q207A, R211S, K223Q, L228R, K238RCRF01_AE
 S0506109S0506109KF292541NRTINNRTIA62V, F116Y, Q151M, M184IK103N, M230LV35T, T39K, T69N, G112A, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I202V, Q207A, L210S, R211SCRF01_AE
 R0413061R0413061KF292462NRTINNRTIM41L, D67N, T69D, L74V, M184V, L210W, T215YA98G, K103N, V108I, M230LV35T, T39E, V60I, V118I, K122E, D123S, S162C, K173L, Q174K, D177E, I178M, R206K, Q207E, R211K, K238RCRF01_AE
 T0115311T0115311KF292605NRTINNRTIL74LV, M184V, T215FK103N, M230LV35T, T39N, V106I, K122E, D123NS, S162C, Q174R, D177E, I178M, Q207A, R211S, K238RCRF01_AE
 Q0817130Q0817130KF292403NRTINNRTID67N, K70R, M184V, T215F, K219EG190A, F227L, M230LV35T, T39K, K43E, K122E, D123S, R125RK, K173I, Q174K, D177E, T200M, Q207A, R211S, K238RCRF01_AE
 03-033403-0334KF292333NRTINNRTIM41L, V75M, M184V, L210W, T215YK103N, V108I, M230LI31IM, V35T, T39E, V60I, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211N, K238RCRF01_AE
 R0411255R0411255KF292466NRTINNRTIM184V, T215FK103N, V108I, M230LV35T, T39E, V60I, S68G, K122E, D123S, I135T, S162C, K173V, Q174K, T200A, R206K, Q207A, R211S, K238SCRF01_AE
 U0316143U0316143KF292765NRTINNRTIM184I, T215TI, K219NK101KN, V108I, Y181C, M230LK22R, E28K, V35T, T39K, K43E, K102Q, K122E, D123N, K173I, Q174K, D177E, T200R, Q207A, R211S, K238RCRF01_AE
Pircher (2013)B1113B1113JX110214D4T, 3TC, AZTNVPM41L, D67N, L74V, M184V, L210W, T215Y, K219KNK103N, M230L, K238TI2IV, E6D, K20R, E28K, K32E, V35T, E36ED, T39K, K43E, E44D, K49R, V60I, K64R, V111I, V118I, K122KE, D123DN, K173A, Q174K, Q207A, H208HY, R211RK, V245ECRF01_AE
Sigaloff (2013)MBA079_0MBA079_0JX182024NRTINNRTIM41L, T69D, M184V, T215YK103N, V108I, M230LV35T, K43E, E44A, V60I, V111I, V118I, K122E, D123S, K173L, Q174K, D177E, V189I, T200A, R206K, Q207A, L210S, R211S, T216M, L228R, V245E, A272P, K275Q, K277R, T286A, E291D, I293V, P294T, E297KCRF01_AE
Khairunisa (2014)DT3DT3KM212875AZT, 3TCEFVD67N, T69D, M184V, L210W, T215YM230LI2V, E6D, V21I, V35T, T39E, E44D, V111I, V118I, D121H, K122E, K173I, Q174K, D177E, I178V, D192N, G196E, Q207E, H208Y, R211K, W212C, H221C, K238R, V245KCRF01_AE