<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation G190S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 16
Patients 54
Isolates 54
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Chantratita (2005)14-006914-0069DQ130989NRTINNRTIM41L, D67E, L74V, M184V, T215FK103N, G190ST39K, K43E, V60I, S68G, V118I, K122E, D123S, I135T, T139K, K166R, K173I, Q174K, D177E, I178M, R206K, Q207A, L210M, R211S, T216L, K238R, V245ECRF01_AE
 14-007214-0072DQ130992NRTINNRTIM41L, M184VK103T, G190ST39K, E42A, K43E, I47T, S48I, K49R, T69N, V111I, K122E, D123S, S162C, K173I, Q174K, D177E, I178L, V179I, G196K, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 14-013314-0133DQ131047NRTINNRTIL74VK103N, G190ST39K, K43E, N57D, V60I, S68G, K122E, D123S, F171Y, K173M, Q174K, D177E, I178M, V179T, T200A, Q207A, R211S, V245ECRF01_AE
 14-014814-0148DQ131062NRTINNRTID67N, T215FY181C, G190ST39K, K43E, K101Q, K122E, D123N, I135L, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 G530G530DQ130534NRTINNRTID67N, K70R, L74I, M184V, T215V, K219QA98G, Y181C, G190ST39K, K43Q, T69N, K101Q, K102R, K122E, D123N, S162N, K173I, Q174K, D177E, Q207A, R211S, D218E, V245ECRF01_AE
 G556G556DQ130557NRTINNRTIL74V, M184VK101E, G190SK43E, K122E, D123S, I135T, R172W, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245MCRF01_AE
 G560G560DQ130560NRTINNRTIL74V, M184VK101E, G190ST39K, K43E, K122E, D123S, I135T, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, I244V, V245ECRF01_AE
 G577G577DQ130575NRTINNRTID67N, K70R, T215FA98G, K101E, G190ST39K, K43E, V60I, K122E, D123S, E138A, I142T, K173T, Q174K, D177E, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 G589G589DQ130587NRTINNRTIM184V, T215YK101E, G190ST39K, K43E, V106I, K122E, D123S, R172K, K173I, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
 G647G647DQ130642NRTINNRTIM184VK101E, G190ST39K, K43E, K46I, K122E, D123N, R143I, Q145H, G152V, S162I, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211S, K238R, V245ECRF01_AE
 G654G654DQ130648NRTINNRTIM184VG190ST39K, K43E, K101Q, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 G671G671DQ130662NRTINNRTIK65RY181C, G190SK43E, S68G, K101X, F116W, K122E, D123N, I135V, K166R, K173I, Q174K, D177E, I178M, G196E, T200I, K201T, Q207A, R211S, H221Y, K238R, V245ECRF01_AE
 G715G715DQ130698NRTINNRTIV75L, M184VK101E, G190ST39K, K43E, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 G721G721DQ130703NRTINNRTIK65R, F116Y, Q151MY181C, G190ST39K, K43E, V60I, S68G, K101Q, K122E, D123S, I159L, S162C, S163C, K173R, Q174E, D177E, I178M, V179I, G196A, T200I, E204K, Q207A, R211S, H221Y, V245ECRF01_AE
 G765G765DQ130743NRTINNRTID67N, M184V, T215YG190ST39K, K43E, K173V, Q174K, D177E, I178L, V179I, T200E, Q207A, R211S, K238R, V245ECRF01_AE
 NP138NP138DQ130764NRTINNRTIA62V, D67N, T69D, F116Y, Q151M, M184V, T215V, K219QK101E, V108I, Y181G, G190ST39K, K43E, V111I, K122E, D123N, P157G, K166E, R172K, K173I, Q174K, D177E, I178M, V179T, I180V, E204Q, Q207A, R211N, F214R, P217PR, D218E, E224G, K238R, T240A, V245ECRF01_AE
 NP293NP293DQ130886NRTINNRTID67N, K70R, L74V, M184V, K219QY181C, G190ST39K, K43E, K64H, T69N, K101Q, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, R211S, L228H, K238R, V245ECRF01_AE
Hsu (2005)BAA161446BAA161446AY870239AZT, 3TCEFV G190SE6D, V35T, T39K, K43E, K122E, D123S, K173A, Q174K, D177E, Q207A, R211S, V245E, T286A, E291D, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, T377L, T386I, K390R, A400TCRF01_AE
Non-B Workgroup (2005)TH_155TH_155AY605568AZT, DDIEFVM41L, D67N, V75L, L210W, T215YK101E, G190SV35T, T39K, K43E, V60I, K82R, K122E, D123S, S162C, K173I, Q174K, D177E, G196E, E203D, Q207A, R211N, K238R, V245E, I257R, Q258PCRF01_AE
 TH_183TH_183AY605591ABCEFVL74VK101E, Y181C, G190SV35T, T39K, K43E, D121H, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200I, Q207A, R211S, H221Y, K238R, V245ECRF01_AE
 TH_701TH_701AY901929D4T, DDIEFVD67N, K70R, K219QG190SV35T, T39K, K43E, K101Q, K103R, K122E, D123S, K173T, Q174K, D177E, V179I, T200A, Q207A, R211S, V245ECRF01_AE
Tee (2006)MYKL182204MYKL1822AY960906NRTIEFVD67N, T215F, K219EK101E, Y181C, G190SL34I, V35T, T39E, V60I, W88C, K122E, D123S, S162Y, K173I, Q174K, D177E, I178L, R206K, Q207A, R211S, V245ECRF01_AE
Zhong (2007)D004905CN_049EF199582NRTINVPK65RY181C, G190SE6D, K11T, K32R, V35T, T39K, K43E, K122E, D123K, K173V, Q174K, D177E, V179T, T200I, I202V, Q207D, R211K, G231E, K238R, V245QCRF01_AE
Koyalta (2009)67TCHAD-67FJ688198D4T, 3TCNVPD67N, M184V, T215FK101E, G190SK43E, D121H, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238RCRF01_AE
Manosuthi (2010)14N132214N1322 D4T, 3TCNVPD67N, K70R, M184V, T215I, K219QK101KHNQ, K103N, G190ST39K, K43E, K122E, D123N, K173V, Q174K, D177E, V179T, T200I, I202V, Q207A, R211S, K238R, V245ECRF01_AE
 250856250856 D4T, 3TCNVPM184VK101E, G190ST39K, K43E, K122E, D123N, Q174K, D177E, E203DN, Q207E, R211RK, K238R, V245TCRF01_AE
 143229143229 D4T, 3TCNVPL74I, M184VA98G, K101E, G190ST39K, K43E, K122E, D123S, I135L, E138G, R172K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 250847250847 D4T, 3TCNVPF116Y, Q151M, M184VV179E, G190ST39E, S68G, D123N, E138G, K173I, Q174K, T200A, Q207A, F214L, V245ECRF01_AE
 25-071025-0710 D4T, 3TCNVPM41L, T69G, V75M, M184V, T215YK101H, G190ST39K, K43E, K122E, D123S, I167V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, I244M, V245R, L246MCRF01_AE
Puthanakit (2010)PHPT105PHPT105 AZT, 3TCNVPM184V, T215FK101E, G190SE6D, K11T, V35T, T39K, K43E, S68G, V106I, K122E, D123S, I135T, K173I, Q174K, Q207A, R211S, E233D, L234F, K238RCRF01_AE
 CR1515CR1515 D4T, 3TCNVPM184V, T215FK101E, G190SV35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, G196R, I202V, Q207A, R211S, V245ECRF01_AE
Bunupuradah (2011)079-001-007079-001-007 TDF, 3TCEFVK65RK101E, Y181C, G190SV35T, T39K, K43E, K122E, D123N, S162Y, K173I, Q174K, D177E, V179I, Q207A, R211S, V245E, K259NCRF01_AE
 079-003-041079-003-041 D4T, 3TCNVPD67N, K70R, M184V, T215F, K219QA98G, K101E, G190SV35T, T39K, K43E, K49R, V60I, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 079-008-019079-008-019 AZT, 3TCNVPD67N, K70R, M184V, T215F, K219QK101E, G190SE28K, V35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, R211K, V245E, K249QCRF01_AE
Ferradini (2011)250656RTHM026328D4T, 3TCEFVM41L, D67N, K70R, L74I, M184V, T215F, K219QA98G, G190SV35T, T39E, V106I, K122E, D123S, S162Y, K173T, Q174K, D177E, I178M, V179I, G196E, E203K, Q207A, H208Y, R211S, K223Q, F227Y, L228H, K238RCRF01_AE
 370352RTHM026340D4T, 3TCEFVM41L, L74V, M184VA98G, Y181C, G190SK20KR, V35T, T39K, T69N, V106I, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, K238RCRF01_AE
Coetzer (2013)KH013KH013KC533604D4T, 3TCNVPD67N, V75M, M184V, L210W, T215FK101E, G190SV35T, K64Y, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179VI, T200A, E203D, Q207A, R211NSCRF01_AE
Jiamsakul (2013)R72075R72075KJ869000TDF, 3TCNVPK65R, V75LK101KE, G190ST39K, K43E, V106I, K122E, D123S, I135T, S162C, K173A, Q174R, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 R12033R12033KJ868958ABC, 3TCEFVL74V, V75L, Y115F, M184VK101E, Y181C, G190SE6D, K22R, V35T, T39K, K43Q, V60I, V106I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178L, T200TI, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, A400TCRF01_AE
 R71128R71128KJ868985TDF, 3TCEFVK65RK101E, Y181C, G190SV35T, T39K, K43E, K122E, D123N, S162Y, K173I, Q174K, D177E, V179I, Q207A, R211S, V245ECRF01_AE
 R12081R12081KJ868964ABC, 3TCEFVK65RK101E, Y181C, G190SE6D, K20R, V35T, T39K, K43Q, V60I, K103R, V118I, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, H221HY, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400TCRF01_AE
 R71102R71102KJ868984TDF, 3TCEFVL74I, M184VG190SV35T, T39K, K43E, K101Q, K122E, D123N, K173V, Q174K, Q207A, R211S, K238R, V245ECRF01_AE
 R12135R12135KJ868966ABC, 3TCEFVK65R, D67G, Y115FY188H, G190SE6D, V35T, T39K, K43E, K101R, K122E, D123S, S162C, R172K, K173T, Q174K, D177E, T200I, I202V, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294Q, E297DG, E312N, I326V, I329V, M357Q, G359S, K366R, T369V, A371V, K390RCRF01_AE
 R72250R72250KJ869011TDF, FTCEFVD67N, M184IK101E, G190ST39K, K43E, W88C, V90I, K122E, D123S, K173I, Q174K, D177E, R206K, Q207A, R211S, K238R, V245QCRF01_AE
Nouhin (2013)S1216269S1216269KF292602NRTINNRTID67N, M184VK101H, G190SA33V, V35T, T39G, K122E, D123N, T165V, K173T, Q174K, D177E, T200A, Q207S, R211S, K238RCRF01_AE
 03-037803-0378KF292325NRTINNRTID67N, K70R, M184V, T215F, K219QK101H, G190SV35T, T39E, E42EG, K122E, D123S, I135T, S162C, K173R, Q174K, D177E, H198HL, Q207A, R211S, K220K*, K238RCRF01_AE
 Q0504105Q0504105KF292368NRTINNRTIM41L, D67N, K70R, L74I, M184V, T215F, K219QA98G, G190SV35T, T39E, V106I, K122E, D123S, S162Y, K173T, Q174K, D177E, I178M, V179I, G196E, E203K, Q207A, H208Y, R211S, K223Q, F227Y, L228H, K238RCRF01_AE
 S0722120S0722120KF292574NRTINNRTIV75M, M184VK101E, G190SV35T, T39K, K43E, K73M, K122E, D123S, I135T, E138EQ, K166R, K173I, Q174K, D177E, T200A, I202V, Q207A, R211SCRF01_AE
 U0205174U0205174KF292745NRTINNRTIK70KR, T215IK101E, Y181C, G190SV35T, T39K, K43E, K49R, K64R, T69N, K122E, D123G, K173A, Q174K, D177E, Q207A, R211S, L228RCRF01_AE
 03-035203-0352KF292315NRTINNRTIM41L, L74V, M184VA98G, Y181C, G190SK20KR, V35T, T39K, T69N, V106I, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, K238RCRF01_AE
 U0720167U0720167KF292801NRTINNRTID67N, V75M, M184V, L210W, T215FK101E, G190SV35T, K64Y, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179VI, T200A, E203D, Q207A, R211NSCRF01_AE
Nerrienet (2014)Q0908149Q0908149JN675888NRTINNRTIM41L, D67N, K70R, V75M, M184V, T215Y, K219QK101E, G190SV35K, T39E, V60I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
Wallis (2014)4149741497KM458493NRTINNRTIM184VG190SE6D, K11T, V35T, T39K, K43E, K49R, S68G, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, T200E, Q207A, R211SCRF01_AE
Zain (2015)MYHIVDR024MYHIVDR024KT281510NRTINNRTI K101KE, G190SE6D, K11KT, V35T, T39K, K43E, K122E, D123X, R172RK, K173X, Q174K, D177E, I178M, T200TA, Q207A, R211S, V245E, T286A, E291D, V292I, E312TCRF01_AE