<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation Y181V
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 35
Isolates 36
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_800TH_800AY901962D4T, 3TCNVPM41L, D67N, K70R, V75M, M184V, T215F, K219QY181VV35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, L228H, V245ECRF01_AE
Manosuthi (2010)250882250882 D4T, 3TCNVP Y181VK43E, T69N, A98S, K102R, K122E, D123S, S162A, K173T, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 25-040925-0409 D4T, 3TCNVPM184VY181VT39K, K43E, V60I, K122E, D123S, I135T, S162A, K173T, Q174K, D177E, I178V, T200I, E203D, Q207A, R211S, V245ECRF01_AE
Puthanakit (2010)CR3338CR3338 D4T, 3TCNVPD67N, K70R, M184V, T215F, K219QK101E, Y181VE28K, V35T, T39K, K43E, T69N, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, T240K, V245ECRF01_AE
 CR3131CR3131 D4T, 3TCNVPM41L, D67N, T69D, K70R, M184V, T215F, K219QY181VV35T, T39K, K43E, V60I, K122E, D123S, S162D, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, D218E, L228H, D237E, K238R, V245QCRF01_AE
 CR2525CR2525 D4T, 3TCNVPM184V, T215FK101H, Y181VV35T, T39E, K122E, D123S, I135T, K173I, Q174K, D177E, I180V, T200A, Q207A, R211S, D218E, V245QCRF01_AE
Bunupuradah (2011)079-011-005079-011-005 D4T, 3TCNVPM184V, T215FY181VV35T, T39K, K43E, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, E248DCRF01_AE
 079-003-011079-003-011 D4T, 3TCNVPD67N, M184V, T215FY181VV35T, T39K, K43E, K122E, D123S, S162T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 079-004-017079-004-017 D4T, 3TC, AZTNVPM41L, A62V, M184V, T215FY181VK20R, V35T, T39K, K43E, K49R, K122E, D123N, I135T, K173R, Q174K, D177E, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 079-010-041079-010-041 D4T, 3TC, AZTNVPD67N, K70R, M184V, T215Y, K219QY181VK20R, V35T, T39K, K43E, A98S, K122E, D123S, K173V, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 079-003-029079-003-029 D4T, 3TCNVPD67N, K70R, M184VY181VV35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245KCRF01_AE
 079-003-046079-003-046 D4T, 3TCNVPM41L, A62V, D67N, Q151M, M184V, T215YV108I, Y181VV35T, T39K, K43E, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, E203D, Q207A, L210S, R211K, H221Y, K238R, V245KCRF01_AE
 079-011-038079-011-038 D4T, 3TCNVPM184VY181VK32E, V35T, T39K, A98S, K122E, D123S, I135K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 pt001pt001 3TC, D4TNVPM41L, V75M, M184V, T215FK101E, V108I, Y181VV35T, T39K, K43E, T69N, V90I, L109I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, D218E, K238R, V245ECRF01_AE
 079-008-018079-008-018 3TC, D4TNVPM41L, T69D, M184V, T215FY181VL34I, V35T, T39K, K43E, K122E, D123S, K173R, Q174K, D177E, I178M, V179I, E203K, Q207A, R211S, F214L, K223E, L228R, K238R, V245E, E248D, S251HCRF01_AE
Coetzer (2013)KH030KH030.1KC533641D4T, 3TCNVPM41L, D67N, M184V, T215YV108VI, Y181VV35T, T39K, K43E, V106I, K122E, D123S, S162C, K173AT, Q174K, D177E, Q207A, R211S, H221Y, K238RCRF01_AE
  KH030.2KC533640D4T, 3TCNVPD67N, M184VY181VV35T, T39K, K43E, V106I, K122E, D123S, S162C, Q174K, D177E, Q207A, R211S, H221HY, K238RCRF01_AE
Nouhin (2013)R1119085R1119085KF292502NRTINNRTIT69S_VS, V75M, M184V, L210LW, T215FK103N, V108I, Y181VK20R, V35I, T39N, K101KR, K122E, D123S, I135T, T139I, K173I, Q174K, D177E, I178M, Q207E, H221HY, L228H, K238RCRF01_AE
 T1001129T1001129KF292697NRTINNRTID67N, K70R, M184V, T215F, K219QY181VV35T, T39K, K43Q, T69N, K122E, D123S, I135M, K173T, Q174K, D177E, I178M, V179I, Q207A, R211S, D218DECRF01_AE
 Q0324095Q0324095KF292359NRTINNRTIM184V, L210W, T215FK101E, V106M, Y181V, G190A, F227LT39R, K43E, E44D, K49R, T69N, L109I, K122E, D123S, I135T, E138A, S162C, K173T, Q174K, N175Y, V179IT, T200A, I202V, E203K, Q207D, R211K, H221Y, K238RCRF01_AE
 T0630343T0630343KF292645NRTINNRTID67N, M184V, T215FY181VK20R, V35T, T39S, K122E, D123S, I135IT, K173R, Q174K, D177E, I178IM, S191SF, T200A, Q207A, R211N, K223Q, W229WR, K238RCRF01_AE
 U1104141U1104141KF292818NRTINNRTID67N, K70KR, M184VY181VV35T, T39E, K122E, D123S, K173IR, Q174K, D177E, T200A, Q207D, K238RCRF01_AE
 U0129034U0129034KF292744NRTINNRTIA62V, D67N, V75I, F77L, F116Y, Q151M, M184VY181VV35T, T39K, K43E, R83K, K122E, D123N, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, H221Y, K238RCRF01_AE
 R0704228R0704228KF292491NRTINNRTIM41L, D67N, K70R, V75L, M184V, L210W, T215Y, K219EY181V, G190GSV35T, T39K, K43E, E44A, K104R, V106VI, K122E, D123S, S162C, K173S, Q174K, D177E, V179VI, T200TK, Q207E, R211K, L228H, K238RCRF01_AE
 U0224166U0224166KF292757NRTINNRTIM41L, D67N, M184V, T215YV108VI, Y181VV35T, T39K, K43E, V106I, K122E, D123S, S162C, K173AT, Q174K, D177E, Q207A, R211S, H221Y, K238RCRF01_AE
 R0611282R0611282KF292486NRTINNRTIM41L, D67N, M184VY181VV35T, T39K, K43E, K122E, D123S, S162C, K173M, Q174K, I178M, I180IL, Q207A, L210M, R211S, H221Y, E224K, K238RCRF01_AE
 U0527364U0527364KF292785NRTINNRTIM184V, T215YY181VV35T, T39N, K122E, D123S, K173T, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 U0316080U0316080KF292767NRTINNRTIV75M, M184V, T215FA98G, V179D, Y181V, G190AK30N, V35K, T39A, T69N, K103R, V106I, V118VI, K122E, D123S, S162C, K173IT, Q174K, D177E, T200A, E203ED, Q207AG, R211S, E224DCRF01_AE
 U0611159U0611159KF292787NRTINNRTID67DN, M184V, T215FY181VV35T, T39DG, G45GR, K49KR, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, I202IV, Q207A, R211K, H221HY, K238RCRF01_AE
 T0319296T0319296KF292621NRTINNRTIM41L, T69D, M184V, L210W, T215YY181VV35T, T39A, E40F, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200A, E203K, Q207D, H208Y, R211K, K223E, L228HCRF01_AE
 S0604377S0604377KF292552NRTINNRTIA62V, D67G, V75M, F77L, Q151M, M184IV108I, Y181VV35T, T39K, K43E, K101Q, K122E, D123S, K173I, Q174K, D177E, G196E, Q207A, R211S, F214L, K238RCRF01_AE
 S0130181S0130181KF292511NRTINNRTIM41L, K70R, V75M, M184V, T215F, K219QY181VV35T, T39K, K43E, V60I, T69N, K122E, D123S, I135L, S162N, K166R, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, D218E, L228R, K238RCRF01_AE
 T0327001T0327001KF292622NRTINNRTIM41L, D67S, K70R, V75M, M184V, L210W, T215F, K219EA98G, V108I, Y181VK20R, V35T, T39K, K43A, V60I, T69N, V118I, K122E, D123S, S162N, K173T, Q174K, D177E, I178M, V179I, T200M, Q207A, R211N, D218E, L228HCRF01_AE
 U0224076U0224076KF292772NRTINNRTIM41L, T69D, M184V, L210W, T215FYY181VV35T, T39K, E42L, K43E, E44A, K49E, K82R, V118I, K122E, D123S, I142V, K173T, Q174K, D177E, V179I, T200A, Q207AT, R211N, L228H, K238RCRF01_AE
 Q1228120Q1228120KF292432NRTINNRTID67N, K70R, M184V, T215F, K219EY181VV35T, T39N, T69N, K122E, D123N, S162SN, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238RCRF01_AE
Nerrienet (2014)S1201062S1201062JN675858NRTINNRTIA62V, V75M, F77L, Q151M, M184VY181VV35IT, T39N, V111I, K122E, D123NS, I135T, K173A, Q174R, D177E, Q207A, R211S, F214L, K238RCRF01_AE