<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation Y181I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 32
Isolates 33
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_196TH_196AY605601AZT, DDINVPM41L, D67N, K70R, L74I, V75A, L210W, T215FY181IV35T, T39K, K43E, E44A, V118I, K122E, D123N, I135L, S162D, K166R, R172K, K173I, Q174K, D177E, I178M, Q207A, R211N, K220G, K238R, V245ECRF01_AE
 TH_501TH_501AY9018623TC, D4TEFVD67N, V75M, M184V, T215FK103N, Y181I, G190AL34I, V35T, T39K, K43E, A98S, K122E, D123S, K173I, Q174K, D177E, T200R, Q207A, R211S, K238R, V245ECRF01_AE
 TH_791TH_791AY901959AZT, DDINVPD67N, F77L, L210W, T215YK103N, Y181IL34I, V35T, T39K, V111I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245ECRF01_AE
Rosen-Zvi (2008)8307p83-2 ABC, 3TCNVPL74I, Y115F, M184VY181IE6G, K11T, K32R, V35T, C38CR, T39K, K43E, T69N, K102R, K122E, D123S, F171Y, K173R, Q174K, D177E, I178M, Q207A, R211S, H221Y, K238R, V245E, K281R, E291D, I293V, E312S, I326V, I329VCRF01_AE
  08p83-3 ABC, 3TCNVPL74I, Y115F, M184VY181IE6D, K11T, K32R, V35T, T39K, K43E, T69N, K102R, K122E, D123S, P150A, F171Y, K173R, Q174K, D177E, I178M, Q207A, R211S, H221Y, V245E, K281R, E291D, I293V, K311KR, E312NCRF01_AE
Manosuthi (2010)14N007414N0074 D4T, 3TCNVPM184VY181IT39K, K43E, K122E, D123S, I142T, K166R, K173I, Q174K, D177E, V179I, T200I, Q207S, R211S, L228P, K238R, V245ECRF01_AE
Zolfo (2010)A13768A 13768 M24HM565558D4T, 3TCNVPY115YF, M184VY181IT39TA, K122E, D123S, S162C, K173L, Q174K, D177E, I178L, Q207A, R211S, K238KR, V245ECRF01_AE
 A14428A 14428 RSHM565611D4T, 3TCNVPM41L, D67N, L74I, M184V, L210W, T215Y, K219NA98G, L100LI, K101E, V108I, Y181I, G190AT39K, K43E, E44A, V60I, V106VI, V118I, K122E, D123S, I135T, S162N, K166R, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211N, V245ECRF01_AE
Bunupuradah (2011)079-006-001079-006-001 D4T, 3TCNVPV75T, M184VY181II31L, V35T, T39K, K43E, T69N, K122E, D123S, I132L, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 079-011-018079-011-018 D4T, 3TCNVPD67N, K70R, M184V, K219QY181IV35T, T39K, K43E, K49R, V60I, K122E, D123S, T139R, K173T, Q174K, I178M, V179I, I202V, Q207A, R211S, F214L, V245ECRF01_AE
 079-011-004079-011-004 D4T, 3TC, AZTNVPM41L, D67G, K70R, M184V, T215F, K219EV179D, Y181IV35T, T39K, K43E, V60I, S68G, T69N, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 079-005-027079-005-027 D4T, 3TCNVPA62V, V75T, M184VY181II31L, V35T, T39K, K43E, K49R, V111I, K122E, D123N, I135M, K166R, K173I, Q174K, D177E, I178M, V179I, G196E, T200M, E203K, Q207A, R211S, V245ECRF01_AE
 079-003-053079-003-053 3TC, D4TNVPK70R, V75M, F77L, M184V, K219QY181IK20R, V35T, T39K, K43E, V60I, T69N, K122E, D123S, A158T, K173A, Q174R, D177E, V179I, E203K, Q207E, D218E, L228R, K238R, V245ECRF01_AE
 079-005-044079-005-044 3TC, D4TNVPF116Y, Q151M, M184VY181IV35T, T39K, K43E, S68G, K122E, D123S, I135T, I142V, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, F214L, K238R, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT2915PHPT2915PR-RTHQ996510TDF, FTCNVPY115F, M184VK101KE, Y181IE6D, K11T, V35T, T39E, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I329VCRF01_AE
Nouhin (2013)T0928256T0928256KF292693NRTINNRTID67G, K70R, M184V, T215TI, K219EY181IV35T, T39K, K43E, S68G, K122E, D123N, I135L, A158T, K173IT, Q174K, D177E, V179I, T200I, Q207A, R211SCRF01_AE
 Q0328177Q0328177KF292364NRTINNRTIK65R, V75I, M184VY181IV35T, T39K, K43E, V60I, S68G, K122E, D123S, I132L, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, F214L, K238RCRF01_AE
 Q0503117Q0503117KF292369NRTINNRTID67N, K70E, V75AK101E, Y181IV35T, T39K, K43E, T69N, K73Q, V106I, K122E, D123S, P157A, K166R, K173L, Q174K, D177E, I178M, T200A, Q207A, R211S, H221YCRF01_AE
 Q0721082Q0721082KF292400NRTINNRTIM184VY181II31L, V35T, T39K, K64R, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, Q207A, R211S, H221Y, K238RCRF01_AE
 U0707227U0707227KF292794NRTINNRTIM184VK103N, Y181IV35T, T39N, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, G196Q, T200A, I202V, Q207A, R211S, F214L, H221HY, K238RCRF01_AE
 R0911140R0911140KF292495NRTINNRTIA62V, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219EY181IV35T, E40EK, S68G, K122E, D123S, I135IV, I142V, K173I, Q174K, D177E, E194D, T200I, Q207A, R211S, F214L, K238RCRF01_AE
 R0316205R0316205KF292445NRTINNRTIK65R, V75A, K219EY181IV35T, T39K, E40G, K43E, V60I, S68G, T69V, K73L, K102E, D123N, P157A, Q174K, D177E, I178M, Q207A, K238RCRF01_AE
 Q0406099Q0406099KF292375NRTINNRTIA62V, F116Y, Q151M, M184VY181IV35T, T39K, K43E, S68G, K122E, D123N, I142T, K166R, F171Y, Q174R, D177E, T200I, I202V, Q207A, R211S, F214LCRF01_AE
 U1126246U1126246KF292825NRTINNRTID67DN, K70KR, V75M, M184VK101E, Y181I, G190AV21I, E28K, V35T, T39G, V60I, T69N, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207N, R211S, K238RCRF01_AE
 R0220214R0220214KF292451NRTINNRTIM41L, D67N, L74LV, V75M, M184V, L210W, T215YL100I, K103N, Y181IV35T, T39A, E44D, V111I, V118I, K122E, D123S, I135T, I159L, T165V, K173I, Q174K, D177E, I178M, V179I, T200A, E203D, Q207K, H208Y, R211D, K223KQ, K238RCRF01_AE
 T0302245T0302245KF292719NRTINNRTID67N, K70R, M184VY181IV35T, T39K, K43E, K122E, D123NS, T165L, K173T, Q174K, D177E, I178V, V179I, I202V, Q207A, R211SCRF01_AE
 P0926044P0926044KF292342NRTINNRTIV75I, M184V, T215YY181IV35T, T39K, K43Q, K49R, V60I, V90I, K122E, D123S, I132L, I135T, S162N, T165I, K173I, Q174K, D177E, I178M, V179VI, T200A, Q207A, R211S, F214LCRF01_AE
 S0125073S0125073KF292508NRTINNRTIM41L, D67N, K70R, V75M, M184V, L210W, T215YA98G, Y181IK20R, K22N, Q23R, W24G, V35T, E44D, K101R, V118VI, K122E, D123S, I135IT, K173T, Q174K, D177E, Q207A, R211N, D218ECRF01_AE
 S0602165S0602165KF292555NRTINNRTIM41L, D67N, M184V, L210W, T215Y, K219NY181IV35T, T39N, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211N, K238RCRF01_AE
Nerrienet (2014)Q0920081Q0920081JN675815NRTINNRTIA62V, K70N, V75I, F77L, Y115F, F116Y, Q151M, M184VY181I, G190AA33V, V35T, T39K, T58N, S68G, T69N, L100V, K101Q, K122E, D123N, S162C, Q174K, D177E, V179I, I202V, Q207A, R211S, F214L, L228R, K238RCRF01_AE
 T0130214T0130214JN675862NRTINNRTIK65R, Q151MY181IV35T, T39K, K43E, S68G, K122E, D123S, I135T, K173T, Q174K, I178L, V179I, G196E, E203K, Q207A, R211S, F214L, K223E, K238RCRF01_AE
 U0407179U0407179JN675838NRTINNRTIM41L, A62V, K65R, K70T, V75I, F77L, Y115F, F116Y, Q151MY181IV35T, T39K, K43E, T58N, S68G, T69I, K122E, D123S, K166R, E169K, K173I, Q174K, D177E, V179I, T200K, Q207A, R211S, F214L, D218ECRF01_AE
 Q0502189Q0502189JN675885NRTINNRTIM184VV108I, Y181IK32I, V35T, T39K, T58TI, S68G, K122E, D123S, I135T, E138A, K173I, Q174K, V179I, G196Q, Q207A, R211S, F214L, H221Y, K238RCRF01_AE