<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation E138Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 19
Isolates 19
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Manosuthi (2010)250728250728 D4T, 3TCNVPD67N, K70R, M184VG190AT39K, K43E, K122E, D123S, E138Q, S162C, K173I, Q174K, D177E, V179I, T200A, Q207S, R211S, K238R, V245ECRF01_AE
 25-026325-0263 D4T, 3TCNVPD67G, K70R, M184V, T215F, K219EK103N, Y181FT39K, K43E, V60I, S68G, K122E, D123S, E138Q, K173V, Q174K, D177E, I178M, Q197E, T200A, Q207A, K238R, V245ECRF01_AE
 250878250878 D4T, 3TCNVPA62V, M184VV179D, G190AT39K, K43E, K122E, D123N, I135T, E138Q, K173I, Q174K, D177E, T200I, Q207A, R211S, V245ECRF01_AE
Puthanakit (2010)CR2544CR2544 D4T, 3TCNVPM184VK103NV35T, T39K, K43E, T69S, K122E, D123S, E138Q, S162C, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 CR3290CR3290 D4T, 3TCNVPM41L, D67N, M184V, L210W, T215YG190AV35T, T39K, K43E, E44D, K101A, K102Q, V118I, D121H, K122E, D123S, E138Q, S162C, K173I, Q174K, D177E, T200A, Q207A, R211N, K238R, V245ECRF01_AE
Bunupuradah (2011)079-003-002079-003-002 D4T, 3TCNVPD67N, M184VK103N, Y181CE28K, K32E, V35T, T39N, K122E, D123S, I135V, E138Q, K173M, Q174K, D177E, T200A, Q207D, R211K, F214L, H221Y, V245ECRF01_AE
 079-003-006079-003-006 D4T, 3TCNVPM41L, M184V, L210W, T215YK103N, K238TV35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, E138Q, T165I, K173S, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 079-010-015079-010-015 D4T, 3TCNVPD67N, K70R, L74V, M184V, K219QK103NK20R, V35T, T39R, K43E, V60I, K64N, K122E, D123S, E138Q, Q174K, D177E, I178M, T200A, E203D, Q207A, K238RCRF01_AE
 079-011-013079-011-013 D4T, 3TCNVPA62V, D67N, V75I, F77L, Q151M, M184V, K219EG190AV35T, T39K, K43E, D121H, K122E, I135T, E138Q, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245E, V261MCRF01_AE
 079-004-008079-004-008 D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215FK103N, K238TV35M, T39K, K43E, V118I, K122E, D123S, E138Q, S162C, K173A, Q174K, N175Y, Q207A, R211S, V245ECRF01_AE
 079-011-017079-011-017 D4T, 3TCNVP, EFVD67N, K70R, M184V, K219QK101P, K103NV35T, T39K, K43E, V60I, T69N, K122E, D123S, E138Q, I142V, S162N, Q174K, D177E, I178M, Q207A, R211S, L228H, K238RCRF01_AE
 079-010-039079-010-039 D4T, 3TCNVP, EFVD67N, K70R, M184V, T215F, K219QA98G, G190AK20R, V35T, T39K, K43E, K101Q, K122E, D123S, E138Q, K173I, Q174K, D177E, I178M, V179I, T200I, I202V, Q207A, R211S, V245KCRF01_AE
 079-001-015079-001-015 D4T, 3TC, AZTNVP Y181CV35T, T39R, K122E, D123S, I135T, E138Q, I159V, Q174E, D177E, V179I, G196E, I202V, Q207A, V245E, E248NCRF01_AE
 079-003-024079-003-024 D4T, 3TCNVPM184VK103N, K238TV35T, T39N, K122E, D123S, E138Q, K166R, K173I, Q174K, D177E, T200K, Q207A, R211S, V245ECRF01_AE
 079-001-022079-001-022 3TC, D4TNVPM41L, V75M, T215YV179DV35T, T39K, K43E, K122E, D123S, E138Q, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
Ferradini (2011)180194RTHM026321AZT, 3TCNVPM41L, M184V, T215FK103NV35T, T39K, K43E, S68G, A98S, K122E, D123S, E138Q, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
Ngo-Giang-Huong (2011)PHPT0026PHPT0026RTHQ996409D4T, 3TCNVPM184VK103NV35T, T39K, K43E, V60I, K122E, D123S, E138Q, I142V, S162A, K173I, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
Coetzer (2013)KH004KH004KC533601D4T, 3TCNVPD67N, M184VK103N, K238TV35T, T39K, K43E, V60I, K122E, D123S, I135T, E138Q, S162C, K173I, Q174K, D177E, V179VI, T200A, Q207A, R211SCRF01_AE
 KH018KH018KC533617D4T, 3TCNVPV75VI, F116Y, Q151M, M184VK103NA33AV, V35T, T39TK, S68G, K122E, D123S, E138Q, S162C, K173I, Q174K, D177E, Q207A, R211SCRF01_AE