<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation E138G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 12
Patients 21
Isolates 21
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Chantratita (2005)14-007814-0078DQ130996NRTINNRTI  T39K, K43E, K122E, D123S, I135T, E138G, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 G628G628DQ130624NRTINNRTIA62V, M184VK101E, G190AT39K, K43E, K122E, D123S, E138G, K173T, Q174K, D177E, I178M, E194D, G196E, T200A, Q207A, R211S, V245ECRF01_AE
Non-B Workgroup (2005)TH_774TH_774AY901952D4T, 3TCNVPM41L, D67N, K70R, L74I, M184V, T215F, K219QA98G, K101E, G190AV35T, T39D, K122E, D123S, E138G, K173T, Q174K, D177E, I178M, T200A, Q207A, R211N, D218E, K238R, V245K, E248DCRF01_AE
Zhong (2007)D002205CN_022EF199565NRTINVPF116Y, Q151MA98G, K103NE6D, K11T, K20R, V35T, T39E, S68G, K122E, D123S, I135L, E138G, R172K, K173A, Q174K, D177E, I178M, T200I, Q207A, R211S, V241C, V245ECRF01_AE
Manosuthi (2010)143229143229 D4T, 3TCNVPL74I, M184VA98G, K101E, G190ST39K, K43E, K122E, D123S, I135L, E138G, R172K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 25-043925-0439 D4T, 3TCNVPF116Y, Q151M, M184VK101E, G190AT39K, K43E, S68G, K122E, D123S, I135L, E138G, S162N, R172K, K173L, Q174K, D177E, I178M, T200A, Q207A, R211S, F214L, V245ECRF01_AE
 250847250847 D4T, 3TCNVPF116Y, Q151M, M184VV179E, G190ST39E, S68G, D123N, E138G, K173I, Q174K, T200A, Q207A, F214L, V245ECRF01_AE
Bunupuradah (2011)079-003-044079-003-044 D4T, 3TCNVPM184VY181CV35T, T39R, K43E, S68G, K102Q, K103A, K122E, D123N, I135T, E138G, A158T, K173T, Q174K, D177E, I178M, V179I, T200I, Q207A, R211K, V245ECRF01_AE
 079-003-054079-003-054 D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215YK103N, K238TV35T, T39K, K43E, E44D, V111I, K122E, D123S, I135L, E138G, K173I, Q174K, D177E, I178L, V179T, Q207A, R211N, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT4163PHPT4163PR-RTHQ996517TDF, FTCEFVV75M, M184VK103NE6D, K11T, V35T, T39K, K43E, V111I, E138G, K173V, Q174K, D177E, I178L, V179IT, T200TI, I202V, Q207A, Y232H, K238S, V245E, K249R, S251C, T286A, E291D, P294PQ, E312NT, I326V, I329VCRF01_AE
Coetzer (2013)KH012KH012KC533627D4T, 3TCNVPA62V, V75I, F116FY, Q151M, M184VG190AI31L, V35K, T39E, S68G, K122E, E138G, K173I, Q174K, I178M, V179I, T200I, Q207A, R211S, K238RCRF01_AE
Jiamsakul (2013)R71188R71188KJ868990AZT, 3TCNVPM184V, T215YK103NV35T, T39K, K43E, E53N, S68G, K122E, D123S, I135L, E138G, I142T, K173E, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
Nouhin (2013)S0626114S0626114KF292569NRTINNRTIA62V, V75I, F116Y, Q151M, M184VK103NI31L, V35I, T39A, K122E, D123S, E138G, S162C, K173R, Q174K, D177E, I178M, E194D, G196E, T200S, Q207A, R211SCRF01_AE
 Q1003147Q1003147KF292418NRTINNRTID67N, M184V, L210W, T215Y, K219NY181C, M230LV35T, T39E, E44D, V111I, K122E, D123S, E138G, K166R, K173I, Q174K, D177E, I178V, G196E, Q207K, R211N, H221Y, K238RCRF01_AE
 U0811077U0811077KF292807NRTINNRTIM41L, L74LI, V75M, M184V, L210W, T215FYA98G, K101E, G190AV35T, T39E, K122E, D123N, I135T, E138G, K173R, Q174K, D177E, I178M, Q207A, R211NSCRF01_AE
 R0521181R0521181KF292479NRTINNRTIM41L, D67N, M184V, T215YK103ND17E, K22KI, I31L, V35T, T39K, K43A, E44D, V118I, K122E, D123N, I135T, E138G, K173I, Q174K, D177E, I178V, G196E, I202V, Q207S, L210S, R211SCRF01_AE
Nerrienet (2014)U0331210U0331210JN675896NRTINNRTIF116Y, Q151M, M184VY181CV35T, T39K, K43E, S68G, K122E, D123N, I135T, E138G, S162T, K173I, Q174K, D177E, T200A, Q207D, H221Y, K238RCRF01_AE
Zain (2015)MYHIVDR106MYHIVDR106KT281572NRTINNRTIM184VK103N, P225HV35T, T39K, T69S, K102KR, K122E, I135T, E138G, G196E, Q207A, R211S, K238R, V245E, T286A, K287T, E291A, V292I, I293V, E297K, E312TCRF01_AE
Rhee (2017)1300113001KY358839TDF, FTCEFVK65R, M184VA98G, K103NK20R, V35T, T39K, K43A, K46Q, S68G, T69I, K102R, K122E, D123S, I135L, E138G, K166KR, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238RCRF01_AE
 1043810438KY359018TDF, 3TCEFVK65RV179D, G190AV35T, T39K, K43E, S68G, T69I, K122E, D123S, I135R, E138G, K173T, Q174K, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 1323713237KY359050TDF, 3TCEFVK65R, M184IK103N, M230LV35T, T39K, K43E, K49R, K122E, D123S, I135T, E138G, S162C, E169D, K173A, Q174R, D177E, I178L, Q207A, R211SCRF01_AE