<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 4
Patients 8
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ly (2007)NL_KHM_HM16HM16W2RDQ831369NoneNVP  V35I, T39A, K64R, K122E, D123S, I135T, E138A, I142V, K173T, Q174K, D177G, I202IV, Q207A, R211S, V245ECRF01_AE
  HM16W6RDQ831435NoneNVP  V35I, T39A, K64R, K122E, D123S, I135T, E138A, I142V, K173T, Q174K, D177G, I202V, Q207A, R211S, V245ECRF01_AE
Germanaud (2010)55135513 AZT, 3TCNVP  V21I, V35T, T39A, V60I, D121Y, K122E, E138A, I142V, S162Y, K173S, Q174K, D177E, T200I, Q207A, R211KCRF01_AE
 55785578 AZT, 3TCNVPT215P V35T, E36A, T39K, K43E, V60I, S68G, V106T, K122P, D123N, I135V, E138A, T139A, I142V, S162H, K173S, Q174H, D177E, I178L, V179M, E194Q, T200I, Q207ACRF01_AE
Manosuthi (2010)250865250865 D4T, 3TCNVPK65R, L74V, Y115FG190ET39K, K43E, S68G, K102R, K122E, D123S, E138A, K166R, E169D, K173M, Q174K, D177E, Q207A, R211S, H221Y, V245ECRF01_AE
 250748250748 D4T, 3TCNVPM184VK103N, M230LT39K, K43E, K122E, D123S, E138A, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, H221Y, V245ECRF01_AE
Bunupuradah (2011)079-004-009079-004-009 D4T, 3TCNVPL74V, M184V, L210W, T215YK103N, P225H, M230LV35M, T39K, K43E, S68G, V118I, K122E, D123S, I135L, E138A, K173I, Q174K, Q207A, R211S, V245ECRF01_AE
 079-007-008079-007-008 D4T, 3TCNVPM184VK101E, G190AV35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, E138A, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 079-004-016079-004-016 D4T, 3TCNVPD67G, K70R, F116Y, Q151M, M184V, K219QK101H, G190AK20R, I31L, V35T, T39E, V60I, S68G, V106I, K122E, D123S, E138A, S162Y, R172K, K173M, Q174K, D177E, I178M, T200A, Q207A, R211S, F214L, K223Q, E224G, P226T, F227Y, K238R, V245ECRF01_AE