<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K103R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 20
Isolates 21
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_648TH_648AY901912AZT, DDIEFVM41L, D67N, K70R, V75L, T215YK101E, G190AE28K, K32E, V35T, T39K, K43E, K103R, K122E, D123N, I135L, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
 TH_675TH_675 AZT, 3TC, D4TEFVM184VV179D, Y188LV35T, T39K, K43E, K103R, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 TH_701TH_701AY901929D4T, DDIEFVD67N, K70R, K219QG190SV35T, T39K, K43E, K101Q, K103R, K122E, D123S, K173T, Q174K, D177E, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 TH_710TH_710AY901934D4T, 3TCEFVM184VV179D, M230LV35T, T39K, K43E, K103R, V111I, D121H, K122E, D123S, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, I244V, V245ECRF01_AE
Luo (2009)wh.189006HBwh.1890FJ375097NRTINNRTI  E6D, K32E, V35T, T39K, K43E, V60I, R83G, K103R, K122E, D123S, I135V, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, A272G, T286A, E291D, V292I, I293V, E312T, I329V, Q332R, Q334LCRF01_AE
Puthanakit (2010)PHPT133PHPT133 D4T, 3TCEFV, NVPA62AV, D67DN, V75VA, M184VV179D, Y188LV35T, T39E, K103R, V111I, K122E, D123S, I135T, K166R, K173I, Q174K, G196GE, Q207A, R211S, F214C, H221HY, K238RCRF01_AE
Zolfo (2010)A15293A 15293 BLHM565491D4T, 3TCNVPK65R, K70R, V75M, F77L, Q151M, K219KEY181CT39E, S68G, K102KR, K103R, K122KE, D123S, I135IT, P157A, A158S, R172K, K173I, Q174K, D177E, I178M, Q207A, R211N, F214L, L228R, K238R, V245ECRF01_AE
  A 15293 M6HM565571D4T, 3TCNVPK65R, K70R, V75M, F77L, Q151M, K219EY181C, G190GAT39E, S68G, K101Q, K103R, V111I, K122KE, D123S, I135IT, P157A, A158S, R172K, K173I, Q174K, D177E, I178M, Q207A, R211N, F214L, D218DE, L228R, K238R, V245ECRF01_AE
Bunupuradah (2011)079-010-002079-010-002 D4T, 3TCNVPK70R, M184VV179D, Y181CV35T, T39K, K43E, T69N, K103R, K122E, D123S, I135V, K173I, Q174K, D177E, T200I, Q207A, R211S, V245QCRF01_AE
 079-011-029079-011-029 ABC, 3TC, DDIEFVL74V, Y115F, M184VV106A, V179D, P225HV35T, T39K, K43E, S68G, V90I, K103R, V111I, K122E, D123N, S162A, K173I, Q174K, D177E, T200A, Q207A, R211N, V245ECRF01_AE
 079-008-015079-008-015 D4T, DDI, 3TC, AZTEFV, NVPD67N, K70R, M184V, T215F, K219EK101P, V179D, M230L, K238TE28K, V35T, T39K, K43E, K49R, V60I, T69N, K103R, V111I, K122E, D123N, I167V, Q174R, D177E, Q207A, R211S, I244V, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT0958PHPT0958RTHQ996431AZT, 3TCNVPM184VV179D, G190AV35T, T39K, K43E, K102R, K103R, K122E, D123S, K173IT, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
Nouhin (2013)R0620455R0620455KF292490NRTINNRTIM41L, V75M, M184V, L210W, T215YV108I, V179D, Y181CV35T, T39N, E44D, V60I, K101I, K103R, K122E, D123S, I135R, K173I, Q174K, D177E, I178L, Q207A, R211S, H221YCRF01_AE
 Q0818285Q0818285KF292406NRTINNRTIM41L, D67N, M184V, L210W, T215YA98G, V179E, G190AV35T, T39K, K43E, K102KR, K103R, K122E, D123S, R125RK, K173IL, Q174K, D177E, I178M, T200A, Q207A, R211S, K238RCRF01_AE
 S1117398S1117398KF292594NRTINNRTIK65R, D67E, V75M, M184V, K219RY181C, G190AV35T, E36R, T39A, E40D, K46Q, K64T, K66D, S68N, K101Q, K103R, K122E, I132L, S162C, K173I, Q174R, D177E, T200A, Q207A, R211SCRF01_AE
 U0316080U0316080KF292767NRTINNRTIV75M, M184V, T215FA98G, V179D, Y181V, G190AK30N, V35K, T39A, T69N, K103R, V106I, V118VI, K122E, D123S, S162C, K173IT, Q174K, D177E, T200A, E203ED, Q207AG, R211S, E224DCRF01_AE
 R0223238R0223238KF292454NRTINNRTIM184VV179D, Y181CV35T, T39K, K43E, K103R, K122E, D123S, K173I, Q174K, T200A, Q207A, R211S, F214L, L228R, K238RCRF01_AE
 T0714066T0714066KF292650NRTINNRTID67N, K70R, M184V, T215TI, K219QV179E, Y181CV35T, T39E, K103R, T107S, K122E, D123N, A158S, K173L, Q174K, D177E, E194ED, I202V, Q207G, R211SCRF01_AE
 T0408079T0408079KF292625NRTINNRTIA62V, D67N, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219QV179D, Y181C, G190AK20R, V35T, T39E, K64H, K103R, V111I, K122E, D123S, S162C, M164L, K173I, Q174K, D177E, T200A, Q207A, R211S, F214L, H221YCRF01_AE
 Q0224125Q0224125KF292355NRTINNRTIM184V, L210W, T215YV179D, Y188LV35T, T39E, E40D, M41V, K43E, K49E, P55PT, S68G, K103R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, F214LCRF01_AE
Nerrienet (2014)U0406184U0406184JN675881NRTINNRTIM184VA98AG, V179D, Y181CK20R, V35T, T39K, K43Q, K102KQ, K103R, K122KE, D123NS, K173I, Q174K, D177E, Q207A, R211S, F214FL, L228LRCRF01_AE