<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K101R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 21
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_445TH_445 3TC, D4TNVPM41L, T215F V35T, T39K, K43E, S68G, K101R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, D218E, V245ECRF01_AE
 TH_626TH_626AY901899D4T, 3TCNVPM184IY181CV35T, T39K, K43E, K101R, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, G196E, T200A, Q207D, R211S, W212G, G213V, D218G, V245ECRF01_AE
 TH_634TH_634 D4T, 3TCNVP  V35T, T39K, K43E, K101R, K122E, D123S, K173I, Q174K, D177E, V179I, H198R, Q207A, R211S, K238R, V245ECRF01_AE
Gody (2008)Pt045Pt045 D4T, 3TCNVPK65KR, V75I, M184VY181CV8I, K11T, V35T, T39R, K43E, S68G, K101R, D121H, K122E, D123S, I132L, F171Y, K173A, Q174K, I202V, Q207A, R211S, H221Y, V245E, K275KR, T286A, A288T, E291D, V292I, I293V, P294T, E312T, I326VCRF01_AE
Manosuthi (2010)250825250825 D4T, 3TCNVPA62V, K65N, M184V, K219RV108I, Y181CT39K, E40A, K43E, G51E, K64R, S68K, K101R, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 250779250779 D4T, 3TCNVPM184VY181CT39K, K43Q, V60I, S68G, K101R, K122E, D123S, I135T, I142T, K173I, Q174K, D177E, I178M, V179I, Q207K, R211S, F214L, H221Y, V245ECRF01_AE
 25-067725-0677 D4T, 3TCNVPK65R, V75M, F77L, F116Y, Q151MK103N, Y181CT39K, K43E, S68G, T69I, V90I, K101R, V118I, K122E, D123N, P157A, K173V, Q174K, I178M, Q207A, R211S, F214L, K223Q, V245ECRF01_AE
 250757250757 D4T, 3TCNVPK65R, M184VV108I, Y181CT39K, K43E, K101R, K122E, D123S, T139R, K173T, Q174K, D177E, I202V, Q207A, K238R, V245QCRF01_AE
Puthanakit (2010)CR2534CR2534 D4T, 3TCNVPM184VY181CV35T, T39K, K43E, K49R, T69N, A98S, K101R, K122E, D123N, I135T, R172K, K173I, Q174K, D177E, I178L, T200A, Q207A, R211K, V245ECRF01_AE
Zolfo (2010)A14683A 14683 M12HM565563D4T, 3TCNVPM184V, T215FK103N, M230LT39K, K43N, S68G, K101R, V106I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, V245ECRF01_AE
 A12500A 12500 RSHM565606D4T, 3TC, AZT, TDFNVPA62V, K65R, M184VY181C, G190AS68SDGN, K101R, K122E, D123S, K173I, Q174K, D177E, I178M, G196R, T200E, Q207G, R211S, K238R, V245ECRF01_AE
  A 12500 M30HM565538D4T, 3TC, AZT, TDFNVPA62AV, K65R, M184V, K219KEY181C, G190AS68SN, K101R, K122E, D123S, K173I, Q174K, D177E, I178M, G196R, T200E, Q207G, R211S, K238R, V245ECRF01_AE
Bunupuradah (2011)079-003-004079-003-004 D4T, 3TCNVPM184V, T215FK103N, Y181CV35T, T39K, K43E, V90I, K101R, K122E, D123S, S162F, E169Q, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 079-011-011079-011-011 D4T, 3TCNVPD67N, K70R, M184V, K219QY181CV35T, T39K, K43E, K101R, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, D218E, K238R, V245ECRF01_AE
 079-003-021079-003-021 D4T, 3TCNVPD67N, K70R, M184V, K219QY181CK20R, V35T, T39K, K43E, V60I, T69N, K101R, K122E, D123S, S162Y, K166R, K173T, Q174K, D177E, Q207A, R211S, L228H, K238R, T240K, V245ECRF01_AE
 079-003-040079-003-040 D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215YK103N, Y181CK32R, V35T, T39K, K43E, E44D, W88C, K101R, V111I, K122E, D123S, S163T, T165I, K173I, Q174K, D177E, T200A, Q207A, R211N, H221Y, K238R, V245E, D250E, S251FCRF01_AE
 079-005-037079-005-037 3TC, D4TNVPM184V, K219EV108I, Y181C, G190AV35T, T39K, K43E, K64R, K101R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211S, H221Y, V245ECRF01_AE
Ngo-Giang-Huong (2011)PHPT0296PHPT0296RTHQ9964173TC, DDINVPL74LV, V75VI, M184VY181CV35T, T39K, K43E, K49R, A98S, K101R, K122E, D123S, I135T, S162SN, Q174R, D177E, I178M, T200A, Q207A, R211S, K238RCRF01_AE
 PHPT1299PHPT1299RTHQ996444D4T, 3TCNVPM184VK103N, Y181CT39K, K43E, K49R, S68G, K101R, K122E, D123N, I135T, T139A, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
 PHPT3992PHPT3992RTHQ996475D4T, 3TCNVPM184VY188LE6D, K11T, V35T, T39K, K43E, K101R, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 PHPT9159PHPT9159RTHQ996480AZT, 3TCEFV Y181CV35T, T39K, K43E, T69N, K101R, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, L228N, K238RCRF01_AE
Coetzer (2013)KH048KH048KC533623D4T, 3TCNVPM184VY181CV35T, T39K, K43E, K49R, K101R, K102Q, K122E, D123N, T139I, K173T, Q174K, D177E, I178M, V179I, T200A, Q207G, R211S, K238RCRF01_AE