<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K101Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 45
Isolates 47
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_640TH_640AY901907D4T, DDINVPM41L, D67N, V75M, L210W, T215Y, K219NY181C, G190AV35T, T39K, K43E, E44D, V60I, K101Q, V118I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178L, T200A, Q207A, R211N, D218E, K238R, V245ECRF01_AE
 TH_667TH_667AY901922AZT, DDINNRTIM41L, D67N, V75M, M184V, T215F, K219QV108I, Y181C, G190AV35T, T39K, K43E, V60I, K101Q, T107S, L109I, K122E, D123S, K173M, Q174K, D177E, Q207A, R211S, H221Y, D237E, I244K, V245KCRF01_AE
 TH_695TH_695AY901926AZT, 3TCEFVM41L, D67N, M184V, T215FV106M, F227LV35T, T39K, K43E, K101Q, K122E, D123S, I135M, K173T, Q174K, D177E, Q207A, K238R, V245ECRF01_AE
 TH_701TH_701AY901929D4T, DDIEFVD67N, K70R, K219QG190SV35T, T39K, K43E, K101Q, K103R, K122E, D123S, K173T, Q174K, D177E, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 TH_730TH_730AY901940AZT, 3TCNVPM184V, T215YK103N, Y181CV35T, T39K, K43E, S68G, K101Q, K122E, D123S, I135T, K173R, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
Tee (2006)MYKL150903MYKL1509AY960890D4T, DDIEFVD67N, K70RY188LV35T, T39K, K43E, K101Q, V106I, K122E, D123S, S162A, K173I, Q174K, D177E, I178V, V179N, Q207A, R211S, K238R, V245ECRF01_AE
  04MYKL1509.1AY960919D4T, DDIEFVD67N, K70R, K219QY188LV35T, T39K, K43E, K101Q, V106I, K122E, D123S, S162A, K173I, Q174K, D177E, I178V, V179I, Q207A, R211S, K238R, V245ECRF01_AE
Liu (2007)fj18fj18EF432716D4T, 3TCNVPD67G, K70RK103NE6D, K11T, V35T, T39K, K43E, V60I, S68G, K101Q, K122E, D123S, I135T, K173I, Q174K, D177E, I178MCRF01_AE
Manosuthi (2010)250861250861 D4T, 3TCNVPM184VY188LT39K, K43E, V60I, K101Q, V106I, K122E, D123S, I135ILPT, K173I, Q174K, D177E, T200A, Q207A, R211S, K238R, T240K, V245ECRF01_AE
 14N085314N0853 D4T, 3TCNVPM41L, D67N, M184V, L210W, T215Y T39K, K43E, E44D, V60I, K101Q, V118I, K122E, D123S, S162Y, K166R, K173I, Q174K, D177E, V179I, Q207A, R211N, V245ECRF01_AE
 25-027525-0275 D4T, 3TCNVPK70R, V75M, M184VY181C, F227LK43E, S68G, K101Q, V106I, K122E, D123S, K173T, Q174K, N175K, I178M, Q207A, R211S, H221Y, K238R, V245ECRF01_AE
 25-046025-0460 D4T, 3TCNVPA62V, V75I, F77L, F116Y, Q151M, M184V, K219EK103KRT, V108I, Y181CT39K, T58N, K82R, K101Q, K122E, D123S, K166R, R172K, K173IL, Q174K, D177E, I178M, Q207A, L210M, R211S, K238R, V245KCRF01_AE
 250772250772 D4T, 3TCNVPM184V, T215TNSY, K219RK103N, V108IT39K, K43E, K101Q, I142V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, L228R, K238R, V245ECRF01_AE
Puthanakit (2010)CR3522CR3522 D4T, 3TCNVPK70R, V75I, M184VV108I, Y181CV35T, T39K, K43E, T58S, K101Q, K122E, D123S, A158T, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, F214L, L228H, V245ECRF01_AE
 PHPT027PHPT027 D4T, 3TCEFVA62AV, F116Y, Q151M, M184VK103N, Y188LT39K, K43E, S68G, K101Q, S105ST, K122E, D123N, I135T, T165I, R172K, K173I, Q174K, Q182H, G196E, T200A, Q207A, R211S, F214L, K238RCRF01_AE
Zolfo (2010)A15293A 15293 M6HM565571D4T, 3TCNVPK65R, K70R, V75M, F77L, Q151M, K219EY181C, G190GAT39E, S68G, K101Q, K103R, V111I, K122KE, D123S, I135IT, P157A, A158S, R172K, K173I, Q174K, D177E, I178M, Q207A, R211N, F214L, D218DE, L228R, K238R, V245ECRF01_AE
 A14708A 14708 M12HM565520D4T, 3TCNVPD67DN, K70KR, M184VG190AT39K, K43E, V60I, K101Q, K122E, D123S, I135L, N137NS, K166R, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V241I, V245ECRF01_AE
  A 14708 M18HM565519D4T, 3TCNVPD67N, K70R, M184V, K219KQG190AT39K, K43E, V60I, K101Q, K122E, D123S, I135L, K166R, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V241I, V245ECRF01_AE
Bunupuradah (2011)079-005-003079-005-003 D4T, 3TCNVPM41L, M184V, T215FY181C, G190AV35T, T39K, K43E, K101Q, K122E, D123N, K173T, Q174K, D177E, I178V, T200A, Q207A, R211S, V245E, K249RCRF01_AE
 079-010-039079-010-039 D4T, 3TCNVP, EFVD67N, K70R, M184V, T215F, K219QA98G, G190AK20R, V35T, T39K, K43E, K101Q, K122E, D123S, E138Q, K173I, Q174K, D177E, I178M, V179I, T200I, I202V, Q207A, R211S, V245KCRF01_AE
 079-003-042079-003-042 D4T, 3TCNVPK70R, M184V, K219QY181CV35T, T39K, K43E, T69N, K101Q, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 079-008-014079-008-014 D4T, 3TC, AZT, TDFNVP, EFVD67N, K70E, V75L, Y115F, M184VK103N, G190AK22R, V35T, T39K, K43E, F87L, K101Q, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211N, H221Y, K238R, V245ECRF01_AE
 079-001-019079-001-019 D4T, 3TC, AZTNVPM41L, L74I, M184V, L210W, T215Y, K219NG190AK20R, V35T, T39K, K43E, E44A, S68G, K101Q, V118I, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211D, V245ECRF01_AE
 079-001-025079-001-025 D4T, 3TC, AZTNVPD67N, F77L, F116Y, Q151M, M184IY188LV35T, T39K, V60I, K101Q, V118I, K122E, D123S, T165I, K173I, Q174K, T200I, I202V, Q207A, R211S, F214L, V245ECRF01_AE
 079-005-035079-005-035 D4T, 3TCEFVM184VK103NV35T, T39K, K43E, K101Q, K102Q, K122E, D123S, S162A, K166R, K173I, Q174K, D177E, I178M, I202V, Q207A, R211S, V245ECRF01_AE
 079-010-047079-010-047 D4T, 3TC, AZTNVPM184VA98G, K103NK20R, V35T, T39K, K43A, K49R, K101Q, K122E, D123N, I135L, S162A, R172K, K173R, Q174K, D177E, I178M, V179I, T200I, Q207D, V245ECRF01_AE
Ferradini (2011)420239RTHM026307AZT, 3TCNVPD67N, K70R, V75M, M184V, L210W, T215F, K219EA98G, Y181CE28A, V35T, T39E, K101Q, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238RCRF01_AE
Ngo-Giang-Huong (2011)PHPT0057PHPT0057RTHQ996414D4T, 3TCNVPM41L, D67N, K70R, M184V, T215FY, K219EA98G, Y181C, G190AK43E, V60I, K101Q, V118I, K122E, D123N, I142V, K173A, Q174K, D177E, I178M, Q207A, L210FY, R211NS, L228HCRF01_AE
Coetzer (2013)KH037KH037KC533597D4T, 3TCNVPK65RY181CV35T, K101Q, V106I, K122E, D123S, A158T, S162C, K173M, Q174K, D177E, Q207A, R211S, H221HY, K238RCRF01_AE
 KH034KH034KC533620D4T, 3TCNVPD67DN, M184VG190AL26L*, V35T, T39K, K43E, V60I, K101Q, K102Q, K122E, D123S, K166KR, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211SCRF01_AE
Nouhin (2013)U0420167U0420167KF292775NRTINNRTIA62V, K65N, D67DN, K70KT, M184V, K219RY181C, G190AI31L, V35Q, T39K, K43E, S68R, K101Q, K122E, D123S, I135IT, K173I, Q174K, D177E, I178M, Q207A, R211S, F214LCRF01_AE
 S1119271S1119271KF292626NRTINNRTID67N, K70R, M184V, K219EY181CV35T, T39K, K43E, K49R, V60I, A98S, K101Q, Y115S, F116V, V118S, P119S, K122E, D123S, R125K, Q145H, Y146C, L149LI, K173I, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 03-023903-0239KF292322NRTINNRTID67N, K70R, V75M, M184V, L210W, T215F, K219EA98G, Y181CE28A, V35T, T39E, K101Q, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238RCRF01_AE
 S0508221S0508221KF292539NRTINNRTIK65RY181CV35T, K101Q, V106I, K122E, D123S, A158T, S162C, K173M, Q174K, D177E, Q207A, R211S, H221HY, K238RCRF01_AE
 S0528179S0528179KF292577NRTINNRTIM41L, V75I, M184V, T215FA98AG, V108I, Y181C, G190AI31L, V35T, T39N, S68SG, K101Q, K122E, D123S, K173KR, Q174QK, D177E, I178M, T200I, Q207A, R211N, K238RCRF01_AE
 T0904064T0904064KF292690NRTINNRTIM184V, L210W, T215Y, K219NY181CE28K, V35T, T39E, A98S, K101Q, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200K, Q207A, R211SCRF01_AE
 S1117398S1117398KF292594NRTINNRTIK65R, D67E, V75M, M184V, K219RY181C, G190AV35T, E36R, T39A, E40D, K46Q, K64T, K66D, S68N, K101Q, K103R, K122E, I132L, S162C, K173I, Q174R, D177E, T200A, Q207A, R211SCRF01_AE
 R0611279R0611279KF292485NRTINNRTIK65KR, L74I, V75AT, Q151LMK103N, Y181CV35T, T39E, S68SG, K101Q, V111I, K122E, D123S, A158AS, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, H221Y, K238KRCRF01_AE
 S0604377S0604377KF292552NRTINNRTIA62V, D67G, V75M, F77L, Q151M, M184IV108I, Y181VV35T, T39K, K43E, K101Q, K122E, D123S, K173I, Q174K, D177E, G196E, Q207A, R211S, F214L, K238RCRF01_AE
 T0603171T0603171KF292637NRTINNRTID67DN, M184VG190AL26L*, V35T, T39K, K43E, V60I, K101Q, K102Q, K122E, D123S, K166KR, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211SCRF01_AE
Pircher (2013)B1119B1119JX110220D4T, 3TC, AZTNVPM41L, M184V, T215YV108I, Y181C, G190A, F227FLE6ED, V35T, T39K, K43E, K49R, T69N, K101Q, L109LI, K122E, S162SN, K173A, Q174K, D177E, T200A, E203V, Q207A, R211N, H221HY, V245ECRF01_AE
Theys (2013)4751147511KC221375NRTI, TDFNNRTID67N, K70G, K219QK103N, E138EGKR, Y181CK43E, T69N, K101Q, K122E, D123S, S162A, K173I, Q174K, D177E, I178L, L187W, I202V, Q207A, R211S, H221Y, L228RCRF01_AE
Nerrienet (2014)T0910001T0910001JN675830NRTINNRTIM41L, D67N, K70R, Q151M, M184V, T215F, K219EV108I, Y181C, G190AV35T, T39K, K43E, T69N, K101Q, K104R, K122E, D123S, S162C, K173T, Q174K, D177E, I178M, G196R, T200A, Q207A, L210S, R211S, D218E, L228H, K238RCRF01_AE
 Q0920081Q0920081JN675815NRTINNRTIA62V, K70N, V75I, F77L, Y115F, F116Y, Q151M, M184VY181I, G190AA33V, V35T, T39K, T58N, S68G, T69N, L100V, K101Q, K122E, D123N, S162C, Q174K, D177E, V179I, I202V, Q207A, R211S, F214L, L228R, K238RCRF01_AE
 U0329191U0329191JN675878NRTINNRTIM41L, L74V, V75IT, T215FV108I, Y181C, G190AI31L, V35T, T39N, S68G, K101Q, V118I, K122E, D123S, F171Y, Q174K, D177E, I178M, G196E, T200I, R206RK, Q207A, R211N, K238RCRF01_AE
 Q1019297Q1019297JN675849NRTINNRTIK65R, Y115F, M184VV108VI, Y181C, G190AV35T, T39K, K43E, S68N, W88C, K101Q, K122E, D123S, S163T, T165I, Q174R, D177E, I178M, T200I, E203D, Q207A, R211S, L228RCRF01_AE
 U0527075U0527075JN675840NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215Y, K219NV108I, Y181C, G190AL34I, V35T, T39K, K43E, E44ED, V60I, K101Q, L109I, V118I, K122E, D123S, K166KR, K173I, Q174K, D177E, T200TA, Q207A, R211KN, D218E, K238RCRF01_AE