<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 13
Patients 47
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Chantratita (2005)14-000914-0009DQ130944NRTINNRTIM41L, D67N, K70R, M184I, L210W, T215YL100I, K103NT39E, V60I, V118I, K122E, D123S, K173I, Q174K, V189I, I202V, Q207A, R211N, V245ECRF01_AE
 14-001514-0015DQ130950NRTINNRTIM41L, L210W, T215Y, K219NL100I, K103NT39K, K43E, E44A, V118I, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211N, L228R, V245ECRF01_AE
 14-009014-0090DQ131006NRTINNRTIL74V, M184VL100I, V179DT39K, K43E, V60I, S68G, K103R, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 14-009314-0093DQ131008NRTINNRTID67N, M184V, T215YL100I, K103NT39K, K43E, E44D, K122E, D123S, I135V, K173I, Q174K, D177E, I178L, T200I, Q207A, R211N, F214L, K238R, V245ECRF01_AE
 G611G611DQ130608NRTINNRTID67N, V75I, T215FL100I, K103NT39K, K43E, V60I, K122E, D123S, T139K, I142V, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 G638G638DQ130633NRTINNRTIM41L, D67N, V75M, L210W, T215YL100I, Y188L, G190AT39K, K43E, N57D, V60I, V106L, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 G752G752DQ130731NRTINNRTI L100I, K103NT39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 G756G756DQ130734NRTINNRTIM41L, A62V, D67N, V75I, F116Y, Q151M, M184I, L210W, T215YL100I, K101E, G190AT39K, K43E, K122E, D123S, S134G, I142V, K173I, Q174K, D177E, I178M, Q207A, R211N, K238R, V245ACRF01_AE
 NP146NP146DQ130771NRTINNRTIM41L, D67N, K70R, V75T, L210W, T215Y, K219DL100I, K103NT39K, K43E, E44A, I94L, K122E, D123N, I142V, S162T, S163T, Q174K, D177E, I178M, Q207A, R211N, V245ECRF01_AE
 NP174NP174DQ130789NRTINNRTIM41L, L74V, M184V, T215FA98G, L100I, K103NT39K, K43E, V60I, V111I, K122E, D123S, S163T, K166R, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 NP268NP268DQ130863NRTINNRTIM41L, D67G, T215YL100I, K103NT39K, K43E, V60I, T69N, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, V245ECRF01_AE
 NP286NP286DQ130880NRTINNRTIM41L, D67G, T215YL100I, K103NT39K, K43E, V60I, T69A, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, V245ECRF01_AE
 NP298NP298DQ130891NRTINNRTIK65R, K219RL100I, K103NT39K, S68G, T69X, V90I, K122E, D123S, S162A, K173I, Q174K, D177E, I178M, T200I, Q207A, L210S, R211SCRF01_AE
Hsu (2005)BAA157676BAA157676AY870181AZT, DDI, D4T, 3TCEFVM41L, L74V, M184V, L210W, T215YL100I, K103NE6D, K20R, V35T, T39K, K43E, E44A, K49R, K122E, D123S, I135M, K173T, Q174K, D177E, I178M, V179I, T200A, Q207D, R211K, L228R, K238R, V245E, T286A, A288T, E291D, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400TCRF01_AE
Non-B Workgroup (2005)TH_162TH_162AY605576ABC, DDIEFVM41L, K70R, L74V, M184VL100I, K103NV35T, T39K, K43E, T69N, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200A, E204Q, Q207A, R211K, V245A, I257R, Q258P, K259QCRF01_AE
 TH_653TH_653AY901916AZT, DDIEFVM41L, D67G, L210W, T215FL100I, K103NV35T, T39K, K43E, V60I, K122E, D123N, I135T, K173L, Q174K, D177E, I178M, V179T, Q197E, Q207A, R211S, V245E, K249QCRF01_AE
Tee (2006)MYKL135603MYKL1356AY960876D4T, DDIEFVM41L, D67G, L74V, T215FL100I, K103NV35K, T39K, K43E, I47F, Y56S, T58I, V60I, S68G, T84I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200E, Q207A, R211S, K223Q, K238R, V245ECRF01_AE
  03MYKL1356.1AY960916D4T, DDIEFVM41L, D67G, L74V, L210W, T215FL100I, K103NV35T, T39K, K43E, V60I, S68G, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200E, Q207A, R211S, K238R, V245ECRF01_AE
 MYKL165204MYKL1652AY960898AZT, 3TCEFVM41L, M184VL100I, K103NL34I, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, R211S, H221Y, L228R, K238R, V245ECRF01_AE
 MYKL195804MYKL1958AY960909NRTI, AZT, 3TCEFVL74VL100I, K103N, P225HV35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
Manosuthi (2010)250745250745 D4T, 3TCNVPD67N, K70R, M184V, T215F, K219EL100I, K103NT39K, K43A, V60I, T69N, V111VIM, K122E, D123S, I135T, K166R, K173IT, Q174K, D177E, T200A, I202V, Q207A, R211S, G213A, L228H, W239WR, V245ECRF01_AE
Bunupuradah (2011)079-008-001079-008-001 D4T, 3TCNVP, EFVM41L, D67N, T69D, K70R, L74I, M184V, T215F, K219QA98G, L100I, K101E, V108IV35T, E36D, T39K, K43E, V60I, K122E, D123S, K173R, Q174K, D177E, V179I, T200A, Q207A, R211N, H221Y, L228H, K238R, V245KCRF01_AE
Ngo-Giang-Huong (2011)PHPT1699PHPT1699RTHQ996494AZT, 3TCEFVD67N, K70R, M184V, T215I, K219EL100I, K103NV35T, T39K, K43E, K122E, D123N, I135IT, I142T, K173A, Q174K, D177E, I178IL, Q207A, R211SCRF01_AE
Jiamsakul (2013)R73061R73061KJ869018TDF, 3TCEFVK65R, Y115F, M184VL100I, K103NE6D, K11T, K20R, V35T, T39E, K122E, D123S, I135IT, T139TK, K166R, K173L, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
Nouhin (2013)R0321184R0321184KF292459NRTINNRTID67G, K70R, M184V, T215I, K219EL100I, K103NV35T, T39E, V60I, S68G, K122E, D123S, I135R, K173L, Q174K, D177E, T200A, Q207A, R211S, K238RCRF01_AE
 T0624301T0624301KF292652NRTINNRTID67G, K70R, L74I, M184V, T215F, K219EL100I, K103NV35T, T39N, S68G, K122E, D123N, K173I, Q174K, D177E, I202V, Q207A, R211S, L228H, K238RCRF01_AE
 S0421065S0421065KF292526NRTINNRTIM41L, D67N, K70R, M184V, L210W, T215F, K219EL100I, G190AV35T, T39K, K43E, E44A, V118I, K122E, D123S, I142V, S162T, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211N, L228HCRF01_AE
 T0804081T0804081KF292683NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215YA98G, L100I, K103NV35T, T39K, K43E, E44D, K49R, V60I, V111I, K122E, D123S, I135T, K173IM, Q174K, N175Y, D177E, K201I, Q207A, R211N, K238RCRF01_AE
Theys (2013)4056340563KC221201NRTI, TDFNNRTIK65RL100I, K103NK43A, V60I, K122E, D123S, K173I, Q174K, D177E, T200TA, Q207A, R211S, K238RCRF01_AE
Zain (2015)MYHIVDR129MYHIVDR129KT281524NRTINNRTIK65R, M184V, K219EL100I, K103N, M230LE6D, K11T, V35T, T39K, S68G, K104R, K122E, D123N, R172K, K173X, Q174K, D177G, I202V, Q207A, R211K, L228Q, K238KR, V245E, A272P, E291D, V292I, I293V, E297K, E312TCRF01_AE
Lam (2016)1201201212012012KR867878TDF, 3TCEFVD67N, K70KT, M184IL100I, V179D, Y181IE6D, V35T, T39K, K43E, K103R, K122E, D123S, I135L, K173I, Q174K, D177E, I178V, T200TA, Q207A, R211S, V245E, A272P, V276I, T286A, E291D, V292I, I293V, E297A, L301IM, E312T, I329V, G335DCRF01_AE
 1202202212022022KR867866TDF, 3TCEFVK65KR, M184VL100I, K103N, P225PHE6D, K11T, V35T, T39K, K43E, T69TN, K122E, D123S, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, E291D, V292VI, I293V, K311R, E312N, D324DE, I329V, G335DCRF01_AE
 1201200912012009KR867933D4T, 3TCNVPM41L, D67G, K70R, L74V, M184V, T215TFIS, K219EQL100I, K103N, K238NE6D, T7TA, K11T, K20R, V35T, T39K, K43E, V60VI, S68G, T69N, K122E, D123N, I135T, K173IR, Q174K, D177E, I178L, V179I, T200E, K201KR, E203EK, E204Q, Q207A, R211K, L228H, V245VA, T286A, E291D, V292I, I293V, E297R, A304E, E312AT, I326V, I329V, G335DCRF01_AE
Rhee (2017)1060410604KY358831TDF, 3TCEFVK65R, M184IL100I, K103N, M230LV35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, V179T, T200I, Q207A, R211S, V245ECRF01_AE
 98C98CKY358870TDF, 3TCEFVL74V, M184VL100I, K101E, G190AL26X, E28K, V35T, T39K, K43E, N54D, V60I, A98S, K104R, K122E, D123S, S162A, K173V, Q174K, D177E, I178L, V179I, T200V, Q207D, R211S, F227X, K238RCRF01_AE
 1048110481KY358880TDF, FTCEFVK65R, Y115FL100I, K103NV35T, T39K, K43E, V60I, K66G, S68G, E89EQ, V90VI, K122E, D123N, K173I, Q174K, D177E, I178M, E194D, T200A, Q207A, R211S, F214L, V245ECRF01_AE
 1224612246KY358884TDF, 3TCEFVK65R, V75M, M184VL100I, K103N, P225HK20R, V35T, T39K, K43E, S68G, K101R, K122E, D123G, I135V, N137S, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, Q222K, K238RCRF01_AE
 1040210402KY358888TDF, 3TCEFVK65RL100I, K103N, V108IV35T, T39K, K43E, S68G, D123N, K173A, Q174K, D177E, T200A, Q207A, R211S, L228R, K238R, V245ECRF01_AE
 1106411064KY358890TDF, 3TCEFVK65R, M184VL100I, K103NV35T, T39K, K43E, V60I, S68G, T107S, K122E, D123S, S162A, K173I, Q174K, Q207A, R211S, H221Y, V245QCRF01_AE
 1143511435KY358923TDF, 3TCEFVK65R, M184IA98G, L100I, K101E, G190AV35T, T39K, K43E, D86E, K122E, D123S, S162H, K173T, Q174K, D177E, V179I, T200E, Q207A, R211S, K238RCRF01_AE
 1009810098KY358934TDF, FTCEFV L100I, K103NK22R, V35T, T39K, K43E, K66G, S68G, K122E, D123S, K173I, Q174K, I178M, Q207A, L210M, R211S, L228R, K238R, V245ECRF01_AE
 1011710117KY358956TDF, 3TCEFVK65RL100I, K103N, P225HV35T, T39K, K43E, K122E, D123N, I135T, S162C, K173I, Q174K, D177E, I178IL, T200A, Q207A, R211S, K238KR, V245ECRF01_AE
 1265512655KY358959TDF, 3TCEFVK65R, M184VL100I, K103NV35T, T39K, K43A, K122E, D123S, I142V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, Y232Y*, K238RCRF01_AE
 1110111101KY358963TDF, 3TCEFVK65R, M184VL100I, K103NV35T, T39K, K43E, K122E, D123S, I135T, K173T, Q174K, D177E, V179IT, T200A, I202IV, Q207A, R211K, K238S, V245ECRF01_AE
 1317113171KY358968TDF, 3TCEFVL74V, Y115F, M184VL100I, K103NK20R, V35T, T39K, K43KE, V60I, W88C, D121H, K122E, I135T, K166R, K173T, Q174R, D177E, I178L, G196E, Q207A, R211S, F214L, K238RCRF01_AE
 1198511985KY358977TDF, 3TCEFVK65KR, Y115YF, M184VL100I, Y188LV35T, T39K, K43E, V60I, S68SG, V106VI, V111I, K122E, D123S, R125RK, M164ML, K173I, Q174K, D177E, I178L, V179IM, T200A, Q207A, L210LS, R211S, F214FL, K238RCRF01_AE
 71387138KY358987TDF, 3TCEFVK65R, M184VL100I, K103NV35T, T39K, K43E, K122E, D123S, Q174E, D177E, T200I, E204K, Q207A, R211S, H221Y, L228R, V245ECRF01_AE
 1029210292KY359051TDF, 3TCEFVK65R, K70KT, M184MIVL100I, K103NK20R, V35T, T39K, S68G, K102R, K122E, D123S, S162AT, K166R, Q174R, I178L, T200I, Q207D, R211K, K238R, V245ECRF01_AE