<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation A98G
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)SA41_1034SA41_1034AY589800DDI, D4TNone A98GV35T, E36V, T39E, S48T, V60I, K104R, K122E, D123S, I135M, K173T, T200A, Q207E, V245Q, D250E, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293VC
  1034_6MAY589801DDI, D4TNone A98GV35T, E36V, T39E, S48T, V60I, K104R, K122E, D123S, I135M, K173T, T200A, Q207E, V245Q, D250E, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293VC
 IL80IL80AY901353AZT, DDI, DDC, D4T, ABC, 3TCNoneM41L, D67N, M184V, L210W, T215YA98GT39E, S48T, V60I, G112X, P119PH, K122E, D123A, F124I, A158S, K173A, Q174K, D177E, T200A, Q207E, R211K, V245QC
 SA75_DR16SA75_DR16AY901709ABC, AZT, 3TCNoneM41L, D67N, T69D, M184V, L210W, T215FA98GV35T, T39E, E44D, S48T, E53D, V111I, V118VI, D121DG, K122E, D123S, E138EA, K173A, Q174K, D177E, G196E, T200A, E203V, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
 IL267IL267AY901762AZT, DDC, 3TCNoneM184VA98GT39E, S48T, K49R, K122E, D123S, I135IMT, A158AS, S162SN, K173AT, D177DE, T200A, Q207E, V245QC
 TK5007TK5007 AZT, 3TCNoneM184VA98GT7P, V35T, T39E, S48T, K64R, K122E, D123S, I135T, K173A, D177E, T200A, Q207N, R211K, V245Q, A272P, K275R, K277R, Q278N, R284RK, T286A, E291D, V292I, I293V, P294T, E297D, L301XC
 PL833877353 AZT, DDI, 3TC, D4TNoneM41L, M184V, T215YA98GV35T, T39DE, S48T, V60I, K122E, D123S, I135V, K173A, D177E, T200A, Q207D, R211K, V245Q, A272P, K277KR, E291D, V292I, I293VC
von Wyl (2007)1017278778EF449991NRTINone A98GV35T, E36A, T39E, S48T, K122E, D123G, K166R, K173A, D177E, T200A, Q207N, R211K, F214LC
Pillay (2008)DR1602ZA.DR16AY589877ABC, AZT, 3TCNoneM41L, D67N, T69D, M184V, L210W, T215FA98GV35T, T39E, E44D, S48T, E53D, V111I, V118VI, D121DG, K122E, D123S, E138EA, K173A, Q174K, D177E, G196E, T200A, E203V, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
Deshpande (2009)Pat21217RTFJ530729AZT, 3TCNoneM41L, M184V, T215YA98GT7P, V35T, T39D, S48T, E53ED, V60I, V111VM, D121Y, K122E, I142V, S162D, K166R, E169K, K173A, D177E, V179I, T200A, I202V, Q207E, R211K, L228Q, V245Q, K249KMC
Grossman (2014)609609KF135112ABC, DDINoneM41L, D67N, L74IV, M184V, L210W, T215Y, K219NA98GT39E, K43Q, E44D, K122E, D123S, I142V, P150T, K173A, Q174K, D177E, T200A, E203K, Q207E, H208Y, R211K, K223E, V245QC
Steegen (2014)10ZAKS02910ZAKS029KJ176311D4T, 3TCNoneD67N, M184VA98GV35T, E36A, T39E, S48T, K66~, K122E, D123G, K173A, D177E, T200A, Q207K, R211Q, V245Q, A272P, E291D, V292I, I293VC