<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation Y318F
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 13
Isolates 13
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Doualla-Bell (2006)Pt7FDB_Pt7EF434895D4T, DDINVPK65RK103KN, Y181C, G190GA, Y318FK22KN, V35T, T39K, S48E, T69N, D123DE, I135IM, K173IT, T200A, Q207E, R211K, V245Q, K277KR, K281KR, T286A, E291D, V292I, I293V, E312F, V314P, Y319CC
Hawkins (2009)R115ZZR115FJ931311D4T, 3TCNVPQ151M, M184VA98G, Y181C, Y318FV35T, T39E, S48T, S68G, K122E, D123N, K173A, D177EG, V179VI, T200A, Q207E, R211K, F214L, H221Y, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, S322AC
Green (2011)707PKE05F707PKE05FHM623497AZT, 3TCNVP, EFVD67N, K70R, M184V, K219QA98G, K103N, Y318FK20KR, V35T, T39E, S48T, V60I, T69TN, K122E, D123S, I135T, S162A, K173A, D177E, T200A, Q207E, R211K, D218E, V245K, A272P, L283I, R284K, V292I, I293V, D324EC
Sigaloff (2011)GT00011000GT00011000_2JN381564D4T, 3TCEFVD67N, M184V, K219QK103N, Y318FV35T, T39E, S48T, V60I, K122E, D123S, I135L, E138A, K173A, I178L, T200A, Q207T, R211K, V245Q, I257IL, A272P, T286A, E291D, I293V, L295I, E308D, I309~C
Sunpath (2013)CAS096CAS096 TDF, 3TCEFVK65R, M184VL100I, K103S, Y318FK20R, V35R, T39D, S48T, K122E, D123S, I135T, K173T, T200A, Q207E, F214L, V245K, A272P, T286A, E291D, V292IC
Theys (2013)BM42108BM42108 AZT, 3TCNVPM184VK103N, Y318FV35T, E36EA, T39E, S48T, K101KR, K122E, D123N, K173R, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, V292I, I293V, E297TC
Steegen (2014)11ZAKS14711ZAKS147KJ176429D4T, 3TCEFVD67N, K70R, V75M, F77L, F116FY, Q151M, M184V, K219QK103N, V106M, Y318FK20R, T27S, V35T, T39A, S48T, V60I, K122E, D123S, E169D, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, D218E, V245Q, T286A, E291D, V292I, I293VC
 12ZAKS21112ZAKS211KJ176491ABC, 3TCEFVA62V, D67N, T69D, Y115F, F116Y, Q151M, M184VK101E, G190S, Y318FE28K, K32E, V35T, E36A, T39D, K122E, D123S, E169Q, P170PH, R172K, K173A, D177G, T200A, Q207A, R211K, V245Q, E291D, V292I, I293V, S322A, Q334N, G335DC
 11ZAKS12711ZAKS127KJ176409D4T, 3TCEFVD67N, K70R, M184V, K219Q, N348IK103N, K238T, Y318FV35T, T39E, T69N, K122E, D123S, E138Q, S162C, K173A, Q174K, N175Y, I178L, E194D, G196V, T200A, K201KI, E203K, Q207E, L228H, E233ED, Q242QE, V245Q, P247A, E248D, D250E, A272P, E291D, V292I, I293V, K311R, D324E, Q334H, G335DC
 12ZAKS23412ZAKS234KJ176513D4T, 3TCEFVM184VA98AG, K103N, V108I, Y318FK20R, T27S, V35T, T39E, S48T, V60I, K102KQ, K122E, D123S, K173R, D177E, I178L, T200A, E204K, Q207E, R211K, F214L, V245L, D250E, A272P, T286A, E291D, V292I, I293V, P294PT, E297A, D324E, I329LC
Skhosana (2015)11ZALS08311ZALS083KM115747D4T, 3TCNVPD67N, K70R, M184V, K219QK103N, Y318FV35T, T39E, S48T, V60VI, K101Q, K102Q, K122E, D123DN, T139R, S162CY, K173A, Q174KNRS, D177E, I178L, G196E, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, K281KR, E291D, V292I, I293V, Q334N, G335DC
 12ZALS11612ZALS116KM115725TDF, 3TCEFVM41L, L74V, M184V, T215FK103N, M230L, L234I, Y318FK22R, E28T, K32E, V35K, E36A, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, I178IM, G196E, T200A, Q207A, R211RK, H221Y, V245T, E248D, A272P, I274V, Q278H, T286A, E291D, V292I, I293V, V317VA, G333D, Q334LC
 11ZALS05111ZALS051KM115853D4T, 3TCNVPM184VK103N, Y318FV35T, T39Q, S48T, K49KR, V60I, K122E, D123S, T165L, E169A, K173A, Q174K, D177E, I178L, G196E, T200A, Q207N, R211K, F214L, D250E, A272P, T286TA, E291D, V292I, I293V, Q334D, G335DC