<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation G190S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 14
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)UK4700UK4700AY9018253TC, DDIEFVM184VK101KE, V106M, G190SV35T, T39E, V60VI, W88C, K122E, D123N, I135T, E138A, K173AT, Q174QK, T200A, E204EK, Q207QK, R211K, F214L, H221HYC
 TK3022TK3022 DDC, AZT, 3TC, D4TEFVD67N, K70R, M184V, K219EG190SK22KR, V35M, T39E, S48T, V90I, K101KQ, K122E, D123S, A158S, K173T, Q174K, D177E, I178L, V179VI, I195L, T200A, V245Q, S251I, A272P, K275R, L283I, E291D, V292I, I293VC
Weber (2005)M72003M72003AY677513AZT, 3TC, D4T, DDINVPD67N, K70R, K219EG190SW24WL, L26X, T27X, E28EA, K30X, V35T, E36A, T39E, S48T, K101KQ, K122E, I135V, K166R, K173T, D177E, T200A, E203K, Q207E, V245Q, D250E, A272P, V292I, I293V, E297EA, D324EC
 F26249F26249AY677547AZT, D4T, 3TC, ABCEFV K101E, Y181C, G190SV35T, T69N, K102Q, K122E, D123G, R172RI, K173T, Q174K, D177E, T200A, Q207E, D218DY, V245Q, E248ED, D250E, A272P, K277R, E291D, V292I, I293VC
Marconi (2008)SW097SW097EU308105D4T, 3TCEFVM184VK101N, G190SS48T, K122E, K173A, Q174K, I178L, G196T, Q197K, T200A, I202V, Q207E, V245QC
Deshpande (2009)Pat17786RTFJ530764D4T, 3TCNVPM184V, T215FA98G, K101E, G190SE28K, V35T, T39E, S48T, V60I, D121Y, K122E, I135L, Q151QH, K173T, D177E, T200A, Q207E, R211KC
Wallis (2009)TJC2436148TJC2436148 AZT, 3TCEFVM184V, T215TNSYG190S, M230MLV35T, T39EK, S48T, K122E, D123N, K173T, T200A, Q207E, R211K, L228LQ, V245K, E248D, D250E, A272P, K277R, Q278N, T286A, V292I, I293VC
 GT00470140GT00470140 D4T, 3TCEFVD67N, M184V, T215F, K219QK101E, G190SV35T, T39E, K122E, D123N, I135L, E138A, K173A, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, R284K, E291D, V292I, I293VC
 GP00005761GP00005761 AZT, 3TCEFVM41L, D67G, K70R, L74V, M184V, K219QK101P, G190SK20KR, V35T, T39E, S48T, V60I, S68G, K122E, D123GS, I135M, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, L228LH, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E308EK, I309IV, D324EC
 GT09066112GT09066112 D4T, 3TCEFVD67N, K70KR, M184V, T215Y, K219EG190SV35T, E36A, T39E, S48T, K101A, K122E, D123G, I135T, S162C, K173T, T200A, E203D, Q207N, R211K, V245Q, A272P, K277R, Q278C, T286A, E291D, V292I, I293V, Q334HC
 TJC2389178TJC2389178 AZT, 3TCEFVM184VK101H, G190SV8VA, G18X, V35T, E36A, T39E, S48T, K122E, D123G, E169EA, K173A, Q174K, D177E, V179VAIT, T200A, Q207E, R211K, V245Q, A272P, L279M, E291D, I293VC
Green (2011)707PKE35F707PKE35FHM623522D4T, 3TCEFVT69TADN, M184V, T215TIK101E, Y181C, G190SV8VA, E28K, V35T, T39E, W88WC, V118I, K122E, D123N, T165I, K166KR, K173A, Q174K, D177E, T200A, Q207E, L210LS, F214L, H221Y, V245Q, A272P, K275KQ, K281R, T286A, E291D, V292I, E297EK, Q334DC
 707PKE41F707PKE41FHM623528D4T, DDIEFVM41L, D67N, L210W, T215YA98G, G190S, K238TE6K, K20R, V35T, T39DE, V60I, V118I, K122E, D123G, K173A, D177E, V179I, T200A, Q207E, R211RK, V245K, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, D324E, I329LC
Brehm (2012)48ZA48ZA.36JN601997D4T, 3TCEFVM184VK103KN, V106VM, G190SV35T, T39K, S48T, V60I, K122E, D123S, I135T, T165I, K173A, Q174K, T200E, E203EK, Q207A, R211K, F214L, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, G335D, R356K, M357MR, G359S, T386V, K390R, A400T, E404D, V435A, E449ED, V466VI, D471E, Q480H, H483H*QY, L491S, L517LI, S519SN, Q520K, K527EGQR, K530R, A534S, A554NSC

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