<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation G190A
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 19
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)UK2069UK2069AY901392DDC, AZT, D4T, DDI, 3TCNoneF116Y, Q151M, M184VG190AK20R, V35T, E36A, T39E, N57Y, V111I, K122E, D123N, A158S, K173A, D177E, T200A, R211K, F214C, Q222QHC
Deshpande (2009)Pat21316RTFJ530728AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219QA98G, K101EQ, G190AK20R, E28EK, V35T, T39D, E44D, S48T, V60I, T69N, D121H, K122E, F124FV, I135T, K173A, Q174R, I178M, T200A, Q207E, R211RK, V245Q, L246WC
 Pat044327FJ530897AZT, 3TCNoneM41ML, D67N, K70R, V75M, M184AV, T215F, K219EG190AL12I, V35T, T39N, V60I, T69TN, D121HY, K122E, I135M, S162SN, K173A, D177E, V179I, E203EV, Q207E, L228H, V245QC
 Pat043329FJ530898AZT, 3TCNoneM41L, D67N, K70R, V75M, M184V, T215F, K219EG190AV35T, T39N, V60I, D121H, K122E, I135M, K173T, D177E, V179I, Q207E, L228H, V245QC
Van Zyl (2013)704311.ZA.EC098KC423703D4T, 3TCNoneM184MVK101E, G190AP9PS, V35T, E36A, T39E, S48T, K122E, D123S, E138A, K173T, Q174K, D177E, T200A, I202V, Q207N, R211KC
 38410.ZA.WC073KC423019ABC, AZT, 3TCNoneM41L, T69D, L210W, T215YG190AV35T, T39N, S48T, V60I, F116S, K122E, D123N, I135T, K173A, Q174K, T200A, Q207E, R211K, V245QC
 60209.ZA.EC015KC424406TDF, AZT, 3TCNoneK219QK101H, G190AV35T, T39E, S48T, V60I, K173A, Q174K, D177E, V179I, T200A, Q207E, R211K, V245QC
 80310.ZA.WC077KC423053ABC, 3TCNoneM41L, D67N, V75M, M184V, T215YA98G, K101E, G190AE28K, K32I, V35T, T39D, S48T, V60I, K122E, D123S, K173A, Q174E, D177E, T200A, Q207E, H208Y, R211K, V245QC
 353911.ZA.GT1732KC423525AZT, 3TCNoneK70KR, M184VG190AV35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, E203EK, E204D, Q207D, R211K, V245Q, D250EC
Acharya (2014)DGP123DGP123KJ185293AZT, 3TCNoneM184VG190AK20R, V35T, E36A, T39D, V60I, K122E, I135V, I142T, K166R, K173A, D177E, T200A, Q207G, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 DGP091DGP091KJ185261AZT, 3TCNoneM184VK101E, G190AV35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, D177E, T200A, Q207E, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, P294QC
 DGP070DGP070KJ185240AZT, 3TCNoneM184V, T215YG190AV35T, E36A, T39E, S48T, V60I, K122E, D123S, I135T, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, K281R, E291D, V292I, I293VC
Neogi (2016)353913.ZA.GT2917KT593229AZT, 3TC, DDINoneD67DN, K70R, M184V, K219EG190AV35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, E203K, E204D, Q207D, R211K, V245Q, D250EC
Posada Cespedes (2017)453315.ZA.WC601 AZT, 3TCNoneM184V, T215FA98G, K101E, G190AV8I, E28K, K32IT, V35K, T39E, S48T, V60I, I132IV, S162Y, K173A, Q174K, D177EG, V179VI, T200A, Q207E, R211K, V245QC
 574015.ZA.EC1591 TDF, 3TCNone G190AV35IT, E36A, T39E, S48T, A98S, K103R, K122E, D123DN, K166R, K173T, D177E, E194D, T200A, Q207A, R211K, V245QC
 129515.ZA.EC1672 TDF, 3TCNoneM184VG190AK32R, V35K, T39D, V60I, K66KR, V106I, D121H, K122E, I142V, K173A, Q174K, D177E, I178L, V179VI, T200A, Q207E, R211K, F214L, V245QC
 50714.ZA.WC459KX544720AZT, 3TCNoneM184VK101E, G190AV35T, E36A, T39E, S48T, K122E, T165I, K173T, D177E, I178M, T200A, Q207A, V245QC
 440115.ZA.WC592 AZT, 3TCNoneM184VA98AG, G190AV21I, V35T, E36A, T39E, S48T, V60I, W88C, K101Q, K122E, D123G, K173A, D177G, T200A, E203K, Q207E, R211K, V245QC
 154212.ZA.GT2434 TDF, 3TCNone K101E, G190AK20R, V35T, T39E, S48T, V60I, A98S, K122E, D123S, I135V, E138A, K173T, Q174K, T200A, Q207E, R211K, D237E, P243T, V245Q, E248D, D250EC
 246515.ZA.GT4468 TDF, 3TCNoneM184VG190AV35T, T39E, S48T, K122E, I135T, K173R, D177E, I178F, Q207K, R211Q, V245HQ, E248D, D250EC