<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation Y188L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 18
Patients 75
Isolates 80
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)UK2086UK2086AY901396AZT, 3TCNVP, EFVD67N, K70R, T215F, K219EY188L, G190AV35T, E36A, T39E, S48T, T69TP, K122E, I142T, R172K, K173A, D177E, I178L, Q207E, K223Q, L228LRC
 IL384IL384bAY901773DDC, AZT, D4T, 3TC, ABC, DDINVPM41L, A62V, T215YY188LT39E, T69A, K104R, K122E, R172RK, K173I, Q174R, D177E, I178L, T200A, Q207E, L228LR, V245QC
 IL642IL642AY901782AZT, 3TC, D4T, DDINVP V179D, Y188LT39E, K122E, D123S, S162A, K173T, D177E, T200A, Q207E, R211K, V245QC
 UK4911UK4911AY901809AZT, 3TCNVPD67N, K70R, M184V, T215F, K219QY188LV35M, T39E, S48T, T69N, K122E, D123S, I135M, D177G, T200A, Q207E, R211KC
 TK2006TK2006a AZT, DDI, 3TC, D4TEFVM184VK103KN, V179FL, Y188LV35T, T39D, S48T, V90I, K101R, K122E, D123G, S162Y, K166KR, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, K277R, I293V, E297K, V317VAC
 TK2010TK2010 AZT, 3TC, DDINVPL74V, M184VY188LV35M, E36A, T39E, K122E, D123G, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, E248X, D250DE, K277R, Q278QK, E291D, V292I, I293V, K311RC
Weber (2005)F16446F16446AY677543DDC, AZT, 3TC, D4T, DDI, ABCNVPD67N, M184V, T215Y, K219KQY188LV35T, T39E, S48T, K64KR, K122E, E138S, V148VG, S162C, K173T, Q174K, D177E, I178L, V179I, G196E, T200A, Q207D, R211K, D237N, V245Q, D250E, I257L, A272S, K281R, E291D, V292I, I293V, E297EK, H315YC
Baxter (2006)48-32293229-30523DQ878136NRTINNRTIM41L, D67N, T69D, V75M, M184V, L210W, T215YV106M, V108I, Y188LE28K, V35T, T39E, E44D, S48T, V60I, S68R, L109V, V118I, K122E, D123S, I135V, S162N, K173T, Q174K, V189I, G196E, T200A, Q207E, R211K, D218E, V245K, D250E, S251D, A272P, V292I, I293V, E297K, Q334L, G335D, R356K, G359T, K366R, A371V, T377L, K390R, K395RC
Doualla-Bell (2006)Pt1FDB_Pt1EF434884AZT, 3TC, D4T, DDINVP Y188LV35T, T39E, S48T, V60I, K122E, D123N, I135L, K173A, D177E, I178M, E194G, T200A, Q207D, R211K, H221Y, L228R, P243T, V245Q, E248T, A272P, E291D, V292I, I293VC
 Pt5FDB_Pt5EF434901AZT, 3TC, D4T, DDINVPM41L, T215YK103KN, Y188LV35T, E36A, T39D, S48T, V60I, V118VI, K122E, D123N, I135RT, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291DC
 Pt12FDB_Pt12EF434902D4T, DDI, AZT, 3TCEFVM41L, D67N, M184V, L210W, T215YY188L, K238KTV35T, E36A, T39D, S48T, V60I, V118I, K122E, D123S, K173A, D177E, I178V, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, E297KC
Lwembe (2007)NYU3838MAUG04 AZT, 3TC, DDINVP, EFVM41L, D67N, K70R, M184V, L210W, T215Y, K219EY188LV35T, T39M, V60I, V106I, L109I, K173E, D177E, G196E, T200A, Q207E, R211K, D218EC
Novitsky (2007)16241624_3549EF026220AZT, DDINNRTID67DGNS, K70R, T215YV106M, Y188LV35T, E36A, T39E, K122E, D123S, I135IL, I142T, K173A, D177E, I178M, T200A, E204K, Q207D, R211K, P243T, V245Q, A272P, K275R, Q278Y, E291D, V292I, I293VC
  1624_0542EF026218AZT, DDINNRTID67N, K70R, T215YV106M, Y188LV35T, E36A, T39E, K122E, D123S, I142T, K173A, D177E, I178M, T200A, E204K, Q207D, R211K, P243T, V245Q, A272P, K275R, Q278Y, E291D, V292I, I293VC
Sen (2007)T111NPT111-PLEF186965D4T, 3TC, DDINVP, EFVM41L, D67N, M184V, T215Y, N348IY188LK20KR, V35T, T39D, E44D, S48T, V60I, V106VL, V118I, D121Y, K122E, I135T, S162A, K166R, K173T, D177E, T200A, Q207E, L210S, D218E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, T377I, K390R, A400TC
 T106NPT106-PLEF186979FTC, D4T, 3TCNVPM41L, D67N, T69D, M184V, T215YY188LV35T, T39D, V60I, V118VI, D121Y, K122E, I135R, S162A, K173T, Q174K, D177E, T200A, Q207E, D218DE, L228LF, V245Q, A272P, K277R, I293V, H315Q, V317A, G335D, R356K, G359T, T377L, K390R, A400T, E404DC
Marconi (2008)ICH01ICH01EU307996D4T, DDI, AZT, 3TCEFVD67N, K70R, M184V, T215TI, K219EK103N, Y188LS48T, A98S, K102T, K122E, D123E, K173A, D177E, I178L, T200A, E204K, Q207E, R211RK, V245QC
 ICH25ICH25EU308015D4T, 3TCEFVM184VK103N, Y188LS48T, W88S, K122E, D123S, T139A, K173I, Q174K, T200A, I202V, Q207E, F214L, H221HYC
 SW002sw002EU308021D4T, 3TCEFVM184VK101E, Y188LK122E, D123DG, G141GR, K173T, Q174K, V179I, T200A, Q207E, R211K, V245LC
 SW037sw037EU308050AZT, D4T, 3TCEFVM184VY188LS48T, V106I, K122E, D123N, I142M, S162Y, K173A, D177G, T200A, Q207D, R211K, V245QC
 SW053sw053EU308064D4T, DDI, AZT, 3TCEFVM41L, M184V, T215YK103N, Y188LV60I, K102Q, S162C, K173A, D177E, T200A, Q207E, V245QC
 SW071SW071EU308082D4T, 3TCNVP, EFVM41L, M184V, T215FA98G, Y188LS48T, V60I, K101KT, K122E, D123S, K173A, Q174K, D177E, G196E, T200A, Q207A, R211K, V245QC
 SW085SW085EU308095D4T, 3TCEFVM184VV179D, Y188LS48T, K122E, D123G, A158AT, T165I, K173A, D177E, T200A, Q207A, R211K, V245QC
 SW093SW093EU308102AZT, 3TCEFVM184VK103N, Y188LS48T, V60I, K122P, I132IV, E138Q, Q145QE, K173A, Q174K, D177E, Q197P, T200A, Q207A, R211K, V245QC
Pillay (2008)DR10DR10AY589872AZT, DDI, D4T, 3TCEFVM41L, D67N, T69D, M184I, L210W, T215YA98G, Y188L, G190AK20R, V35T, T39E, E44D, S48T, V60I, V118I, K122E, D123G, K166R, K173A, D177E, T200A, Q207E, H208HY, R211K, V245Q, A272P, K277R, L279M, T286A, E291D, V292I, I293VC
 DR8403ZA.DR84AY589927D4T, DDIEFV V179D, Y188L, G190AV8I, V35K, T39E, S48E, V60I, K103R, I159V, K173T, Q174K, T200A, Q207E, R211K, V245Q, D250E, A272P, K277T, K281KR, T286A, V292I, I293V, E297K, L301FC
Deshpande (2009)Pat23534artFJ530706NRTINNRTIM41LQ, D67DN, L74LV, M184VV106M, V179VD, Y188LV35T, T39D, S48T, V60I, K122E, I135T, Q151QR, P157PS, K173A, Q174R, N175Y, D177E, I178L, T200A, Q207E, H208Y, F214L, K238YC
 Pat22846artFJ530713AZT, 3TCNVPM41L, M184V, L210W, T215YY188LV35T, T39DN, E44ED, S48T, V60I, D121H, K122E, K173KT, D177E, I178L, V179I, T200A, I202V, E203EA, Q207E, H208HY, R211K, H221HY, V245QC
 Pat18468RTFJ530757AZT, 3TCNVP, EFVK70R, M184VY188LV35T, E36A, T39D, S48T, V60I, T69S, D121Y, K122E, D123E, I135T, S162A, K173A, D177E, T200A, Q207E, R211K, V245QC
 Pat164131RTFJ530777AZT, 3TCNVPM41L, D67N, M184V, T215YY188LV35N, T39D, E44D, V60I, D121Y, K122E, D123E, K173T, D177E, T200A, Q207E, L210S, R211KC
 Pat117227RTFJ530824NRTINNRTIM41L, D67N, M184V, T215Y, K219NA98G, Y188LV35T, T39D, E44D, S48T, V60I, K102R, D121H, K122E, I142V, F160C, K173T, D177E, I178L, V179I, T200A, I202V, E203A, L205S, Q207E, H208Y, L210S, R211K, H221Y, V245Q, K249HC
 Pat112234RTFJ530829D4T, 3TCNVPM184V, T215YY188LM16MT, K20R, K32N, V35K, T39D, V60I, A98AS, V118I, D121H, K122E, I135IT, K166R, K173A, D177E, V179I, E194D, T200A, Q207E, R211K, V245EC
 Pat092261RTFJ530849NRTINNRTIM184V, T215FY188LE6D, G15R, V35T, T39N, V60I, D121Y, K122E, I135T, S162A, K173L, D177E, E194N, T200A, Q207E, R211K, V245QC
 Pat035350RTFJ530906D4T, 3TCNVPM41L, D67N, T69D, Q151M, M184V, T215YY188LK20KR, V35T, T39D, K43R, V60I, D121H, K122E, D123E, I135V, S162A, K173A, Q174K, D177E, V179I, T200AV, Q207E, R211K, F214L, V245QC
 Pat030364RTFJ530911AZT, 3TCNVPM41L, D67N, M184V, T215YY188LV35T, T39D, V60I, D121Y, K122E, I135R, S162A, K173T, Q174R, D177G, G196E, T200A, Q207E, L210S, R211K, D218E, V245QC
 Pat025378rtFJ530916AZT, D4TNVPD67N, K70R, M184V, T215Y, K219EY188LE28K, K32E, V35T, E36A, T39E, S48T, V60I, D121DY, K122E, D123S, K173A, D177E, V189I, T200A, Q207E, V245QC
 Pat011427RTFJ530930NRTINNRTIM41L, L74V, M184V, T215Y, K219KEY181C, Y188LV35T, T39E, E44ED, S48T, D121H, K122E, I135V, S162C, K173AT, Q174K, D177E, T200A, Q207E, R211K, L228H, V245QC
 Pat008439RTFJ530933AZT, 3TCEFVM184VY188L, P225HV35T, E36EA, T39D, V60I, D121H, K122E, K166R, K173A, D177E, I195IL, T200A, Q207E, R211K, F214FL, V245QC
 Pat001VR014RTFJ530940D4T, 3TCNVPT69~, V75T, Q151M, M184VY188LV35T, I37M, T39N, S48T, V60I, S68G, D121Y, K122E, D123E, I142V, K173A, D177E, V179I, V189I, T200A, I202IV, Q207G, R211K, F214L, L228Q, V245QC
Hoffmann (2009)pat022MD122532 AZT, 3TCEFVK70KR, M184VV106M, Y188LV35T, E36A, T39E, S48T, K173M, Q174K, D177E, G196T, T200A, E203EK, Q207E, R211K, F214FL, V245Q, A272PC
 pat028MD24064 AZT, 3TCEFVM184VK101E, E138K, Y188LT27S, V35T, E36A, T39E, S48T, P52S, K103R, K122E, D123S, I135V, S162C, K173T, D177E, T200A, Q207A, R211K, V245Q, A272PC
  MD118823 AZT, 3TCEFVM184VK101E, E138K, Y188L, G190AT27S, V35T, E36A, T39E, S48T, K103R, K122E, D123S, I135V, S162C, K173T, D177E, T200A, Q207A, R211K, V245Q, D250DE, A272PC
 pat054MD31035 AZT, 3TCEFVD67N, K70R, M184V, T215F, K219QA98G, V106M, Y188LV35T, T39E, S48T, V60I, K122E, D123N, T200A, I202V, Q207E, R211K, F214L, V245Q, A272PC
Hosseinipour (2009)71357135GQ228298D4T, 3TCNVPM41L, D67DN, M184V, T215YY188LT39E, E44D, S48T, V60I, V118I, K122E, D123G, I135L, K166R, K173A, Q174R, D177E, I178M, V179VI, I195L, G196N, T200A, Q207E, L210S, R211K, D218DE, V245QC
 84558455GQ228306D4T, 3TCNVPM184VK101KE, Y188LC38C*, T39K, E40EK, K43E, S48T, D123E, E138A, Q197P, T200E, Q207KN, R211K, V245QC
 93449344GQ228325D4T, 3TCNVPM41L, D67N, T69TADN, M184V, L210LW, T215YA98G, Y188LT39E, E44D, V60VI, L100LV, V118I, K122E, D123N, S162SDGN, K173A, Q174EK, D177G, G196V, T200A, Q207E, H208HY, R211RK, W212WLMR, D218DEC
 93819381GQ228362D4T, 3TCNVPK65KR, M184VA98AG, Y188LT39E, S48T, T69TN, D121H, K122E, T139A, K173T, Q174K, D177E, T200A, Q207E, R211K, L228LR, D237DH, V245KQC
 79157915GQ228374D4T, 3TCNVPM41L, D67N, M184V, L210W, T215Y, K219NY188LT39E, E44D, S48T, V118I, K122E, K173T, T200A, Q207E, H208Y, R211K, V245QC
 87708770GQ228382D4T, 3TCNVPD67N, K70R, M184V, T215F, K219QY188LT39E, S48T, K122E, D123S, I135T, I167V, K173A, Q174K, D177E, V179I, G196T, T200A, I202V, Q207E, R211RK, V245RC
Wallis (2009)TJC2388340TJC2388340 AZT, 3TCEFVM184VV106M, Y188LL12LI, V35T, E36A, T39E, S48T, K122E, D123N, K173A, Q174K, T200A, Q207A, R211K, F214L, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, L310FC
 23450232345023 D4T, 3TCEFVM184VY188LK30KE, V35T, T39K, S48T, V90I, K101Q, K122E, D123S, I135IT, K173A, I178L, V179I, T200A, Q207N, R211K, V245Q, E248EK, A272S, K277R, L283LF, T286TA, E291D, V292I, I293V, L303LWC
 23254002325400 D4T, 3TCEFVM184VL100LI, Y188L, G190GAV35T, T39E, S48T, V60I, T69TN, K122E, D123G, K166R, E169A, K173A, Q174E, D177E, T200A, Q207N, F214FL, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, E308K, I309F, L310LR, D324EC
 GT00251488GT00251488 AZT, 3TCEFVM184V, T215YY188LV35T, E36A, T39E, K102W, K122E, D123G, K173A, Q174K, N175NY, D177E, T200A, Q207E, R211K, D218E, V245Q, A272P, K277R, T286A, E291D, V292I, E297DC
 TJC2394661TJC2394661 D4T, 3TCEFVD67DN, K70R, M184VY188L, K238KTE6D, V35T, T39E, E40D, K103KQ, K122E, D123S, K173T, Q174K, T200A, Q207K, R211Q, F214L, V245Q, A272P, L279M, T286A, E291D, V292I, I293V, V317AC
 22717932271793 D4T, 3TCNVPM184VY188LV35T, T39E, S48T, V60I, V118I, K122E, D123G, I135IV, S162C, K166R, K173A, D177E, T200A, E203EK, Q207E, R211K, V245EK, A272P, E291D, V292I, I293V, D324EC
 TJC2367413TJC2367413 D4T, 3TCEFVM184VV106M, Y188LE6K, V35T, T39E, S48T, S105T, K122E, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, A272P, E291D, V292I, I293VC
 23427082342708 D4T, 3TCEFVM184VK103N, Y188LV35T, E36A, T39E, S48T, E53ED, A98S, K102G, K122E, D123GS, I135*, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248ED, A272S, K277R, T286A, V292I, I293V, P294PTC
 TJC2388028TJC2388028 D4T, 3TCEFVM41L, D67N, K70R, M184V, T215YV106M, Y188LT27S, V35T, V60I, K122E, I135L, K173A, T200A, Q207E, V245Q, A272Q, T286A, E291D, V292I, I293VC
 TJC2409904TJC2409904 AZT, 3TCEFVM41L, D67N, M184V, L210W, T215YK103N, Y188LV35T, T39Q, S48T, K102Q, K122E, D123G, F130I, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, A272P, Q278H, E291D, V292I, I293V, I329LC
 TJC2434999TJC2434999 AZT, 3TCEFVM184VY188LV35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, S162A, K173A, Q174A, D177E, T200A, Q207E, R211K, V245Q, S251I, A272P, K281R, T286A, E291D, V292IC
 TJC2411483TJC2411483 D4T, 3TCEFVM184VV179D, Y188LE6K, K11Q, K20R, V35T, T39E, V118I, K122E, D123G, K173T, Q174R, D177E, T200A, Q207E, R211Q, F214L, V245Q, A272P, K277R, E291D, V292I, I293VC
 TJC2381560TJC2381560 D4T, 3TCEFVK65KR, M184VK103KN, V106M, Y188LP4S, V35T, E36A, T39E, S48T, K122KE, D123E, S162A, K173T, V179VI, Q197AE, T200A, Q207E, R211K, V245Q, A272P, K277R, L283I, E291D, V292I, I293VC
 23323872332387 D4T, 3TCEFVM184VL100LI, K103KN, V106VM, Y188L, G190GAV35T, T39E, S48T, V60I, T69TN, K122E, D123G, K166R, E169A, K173A, Q174E, D177E, T200A, Q207N, F214FL, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, E308D, I309F, L310F, D324E, K331NC
 TJC2499250TJC2499250 AZT, 3TCEFVM41L, D67N, K70R, M184V, T215FY, K219EQY188LK20R, V35T, T39E, V90I, A98S, K102X, K103R, K104Q, K122E, D123G, S162Y, K173A, D177E, V179I, T200A, E203K, Q207E, F214FL, L228LH, V245Q, D250DE, A272P, K277R, L283I, T286A, A288T, V292I, I293V, S322A, D324EC
Deshpande (2010)14IND42614IND426GU108152D4T, 3TCEFVT69~, V75T, Q151M, M184VY188LV35T, I37M, T39N, S48T, V60I, S68G, D121Y, K122E, D123E, I142V, K173A, D177E, V179I, V189I, T200A, I202V, Q207G, R211K, F214L, L228Q, V245QC
 23IND4323IND43GU108156AZT, 3TCNVPM41L, D67N, K70R, M184V, T215Y, K219EY188LE28K, K32E, V35T, E36A, T39E, S48T, V60I, I94L, K122E, D123N, K173T, D177E, V189I, T200A, Q207E, H208Y, L228H, V245QC
 67IND4567IND45GU108176AZT, 3TCNVPM41ML, D67DN, M184MV, T215TNY188LV35M, T39E, E44ED, S48T, V60I, R172RK, K173T, Q174K, D177E, I178LM, T200A, E203ED, Q207AEKT, H208HY, R211K, H221HY, K223KE, V245QC
El-Khatib (2010)Pat01110ZA_SAVE1154HQ012289AZT, 3TCEFVM41L, D67DN, K70KR, M184V, T215YV106M, Y188LV35T, T39E, S48T, K122E, D123S, I135V, S162C, K173A, Q174K, T200A, Q207E, R211K, H221Y, Y232H, V245QC
 Pat02610ZA_SAVE1400HQ012304D4T, 3TCEFVM184IK101KE, Y188LV35T, E36A, T39E, S48T, K122E, I142V, K173E, D177E, I178M, T200A, E204K, Q207D, R211K, V245Q, D250EC
 Pat04410ZA_SAVE2201HQ012322D4T, 3TCEFVM184VK103N, Y188LV35T, E36A, T39D, S48T, K122E, E138A, I142V, S162A, E169Q, K173I, Q174K, T200A, I202V, Q207E, R211T, V245H, E248DC
 Pat05310ZA_SAVE2314HQ012331AZT, 3TCEFVM184VV106M, Y188LV35T, E36A, T39E, S48T, V60I, K102R, K122E, D123G, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250EC
 Pat05410ZA_SAVE2320HQ012332D4T, 3TCEFVM184VY188LV35T, E36A, T39E, S48T, V106L, V118I, K122E, D123N, E138Q, T165TI, K173IRT, Q174K, T200A, Q207E, R211K, F214L, V245Q, D250EC
 Pat06410ZA_SAVE2401HQ012342D4T, 3TCEFVM184VY188LV35T, T39E, S48T, K122E, I135IM, K166R, K173A, Q174K, D177E, R211K, V245QC
 Pat07410ZA_SAVE2481HQ012352ABC, 3TCEFVM184VY188LV35T, E36A, T39E, S48T, V60I, K122E, D123S, K173T, D177E, I178IM, T200A, Q207E, R211K, K238R, T240K, V245T, S251NC
 Pat11211ZA_SAVE2283JF960562NRTI, D4T, 3TCNNRTIM184VK101KE, Y188LV35K, E36A, T39E, S48T, E53D, V60VI, V106VI, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, A272PC
Green (2011)707PKE25F707PKE25FHM623514D4T, 3TCEFVM41ML, D67DN, K70KR, M184V, T215TNSY, K219KQV179D, Y188LE28A, V35T, T39E, S48T, V60I, K103R, K122E, D123G, I135IATV, I142T, K173A, D177DE, I178L, T200A, Q207E, R211RK, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 707PKE49F707PKE49FHM623531D4T, 3TC, AZT, DDIEFVM41L, L210W, T215YK103N, Y188LV35I, T39E, E44ED, S48T, A98AS, K102G, K122E, D123S, K173T, Q174K, T200A, Q207A, H208HY, R211K, F214FL, V245E, K277R, L283I, T286A, E291D, V292I, I293V, E297EK, D324E, I329LC
 707PKE52F707PKE52FHM623534D4T, 3TCEFVD67G, K70R, M184V, K219QA98AG, K103KN, V106VM, Y188LK11KR, V35T, T39E, S48T, E53D, V60I, S68G, K102KE, V118VI, K122E, D123S, I135V, K173A, Q174R, D177E, G196GE, T200A, Q207E, R211K, F214L, L228H, Q242H, V245Q, A272Q, T286TA, E291D, V292I, I293V, D324E, G333E, Q334HC
Sigaloff (2011)GT00251488GT00251488JN381583AZT, 3TCEFVM184V, T215YY188LV35T, E36A, T39E, K102W, K122E, D123G, K173A, Q174K, N175NY, D177E, T200A, Q207E, R211K, D218E, V245Q, A272P, K277R, T286A, E291D, V292I, E297DC
van Zyl (2011)A340A340JN638200D4T, 3TCEFVM184VV179D, Y188LV35T, T39E, S48T, K122E, D123N, I135T, K173A, Q174E, D177E, T200A, Q207E, K238R, V245QC

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