<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation Y188H
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 11
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Novitsky (2007)16241624_7985EF026217AZT, DDINNRTIL74V, T215YV106M, Y188H, M230LV35T, E36A, T39E, K122E, D123S, I142T, K173A, D177E, I178M, V179VI, T200A, E204K, Q207D, R211K, P243T, V245Q, A272P, K275R, Q278Y, E291D, V292I, I293VC
Marconi (2008)SW029sw029EU308042AZT, 3TCEFVD67NV106M, Y188HE44EG, S48T, V60I, R72RT, K122E, D123G, K173A, Q174K, D177E, T200E, I202V, Q207E, I244V, V245QC
Deshpande (2009)Pat25404artFJ530687D4T, 3TCEFVV75M, M184V, T215FIK103N, Y188HT7P, V35T, T39D, G51R, V60I, A98AS, V111I, D121H, K122E, I135T, S162H, K173A, Q174R, D177E, V179IT, G196E, T200A, I202IV, Q207E, R211K, L228LQ, Q242QH, V245QC
 Pat057329aRTFJ530884NRTINNRTIM41L, D67DN, V75M, F77L, Q151QKLM, M184V, T215FK103N, Y188HV35T, T39D, V60I, T69TN, V111I, D121H, K122E, I135T, E138EQ, S162H, K173A, Q174R, D177E, V179T, G196E, T200A, I202IT, Q207E, R211K, L228Q, Y232YH, Q242H, V245Q, K249NC
Hoffmann (2009)pat022MD035457 AZT, 3TCEFVM184VV106M, Y188HV35T, E36A, T39E, S48T, K173M, Q174K, D177E, G196T, T200A, Q207E, R211K, V245Q, A272PC
Wallis (2009)TJC2386028TJC2386028 D4T, 3TCEFVM184VK103N, Y188HV35T, E36A, T39E, S48T, W88C, K122E, S162AD, K173A, Q174K, T200E, I202V, Q207E, R211K, V245E, A272P, K281R, E291D, V292I, I293V, H315QC
 AACS7925AAACS7925A AZT, 3TCEFVD67N, K70R, M184V, K219EK103N, Y188HK20R, V35T, E36A, T39E, E40D, V60I, D121H, K122E, K173RT, Q174K, D177E, I178L, G196E, T200A, Q207E, L228H, V245E, D250DE, S251SCG, A272P, K277KR, T286A, E291D, V292IC
 TJC2378119TJC2378119 D4T, 3TCEFVD67N, F116Y, Q151M, M184IK103N, Y188HV35T, E36A, T39E, K122E, D123S, I142V, K173T, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, E248T, E291D, V292I, I293V, I309V, K311RC
El-Khatib (2010)Pat04210ZA_SAVE2197HQ012320D4T, 3TCEFVL74IV, M184VK103S, Y188HV35T, T39E, S48T, E53D, S68G, K122E, D123N, K173T, T200A, Q207E, R211K, V245N, S251NC
van Zyl (2011)A280A280JN638171D4T, 3TCEFV V106M, Y188HE6K, V35T, E36A, T39E, S48T, V60I, K122E, K166Q, K173A, Q174K, D177E, T200A, Q207A, R211K, V245QC
Brehm (2012)53ZA53ZA.48JN602008D4T, 3TCEFVA62V, M184VV106M, Y188HV35T, E36A, T39E, K122E, D123S, K173A, D177E, T200A, Q207D, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, D324E, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, E432D, V435A, L452I, R461Q, V466I, V467VI, S468T, T470N, D471E, T477A, H483Q, S519N, K527N, K530R, A534S, A554SC

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