<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation V179E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 19
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Seoighe (2007)PL17206_PL172V2EF382106NoneNVP V179EK30I, V35T, T39K, V60I, I135IT, A158S, S162Y, K173T, Q174K, D177E, T200A, Q207E, R211RK, F214FL, V245VA, K249R, S251H, A272P, E291D, V292I, I293V, P294PTC
Wallis (2009)22803932280393 AZT, 3TCEFVM184VV106M, V179EK20R, V35T, T39E, S48T, K49R, V60I, E138A, T139I, K173T, Q174K, T200A, I202IV, Q207E, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, P321T, D324E, I326IMC
 23674142367414 AZT, 3TCEFVM41L, D67N, T69D, L74V, M184V, L210W, T215YK103N, V179E, M230LS3C, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, V111VIM, P119PL, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, D324EC
 TJC2367640TJC2367640 D4T, 3TCEFVV75I, M184VV106M, V179EV8VI, K11Q, V35T, T39E, S48T, K122E, D123N, I132L, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, L283I, T286V, E291D, V292I, I293VC
 23567552356755 AZT, 3TCEFVM41L, D67N, T69D, L74V, M184V, L210W, T215YK103N, V179E, M230LS3SC, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, V111VIM, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, L310LQ, D324EC
El-Khatib (2010)Pat07510ZA_SAVE2491HQ012353D4T, 3TCEFVA62AV, M184VV106M, V179E, F227FLV35T, T39E, S48T, E53D, V118I, K122E, D123N, I135T, E138A, Q145H, K173T, Q174R, T200A, Q207G, R211K, F214L, V245Q, E248DC
Sunpath (2013)CAS043CAS043 TDF, 3TCEFVD67DN, M184IV108I, V179E, Y181CK20R, V35T, E36A, T39K, K43E, S48T, V60I, V90VI, K102Q, K103R, K122E, D123N, Q174K, D177E, V189VI, T200A, R211K, F214L, H221HY, V245Q, A272P, A288S, E291D, V292I, I293VC
Van Zyl (2013)14071550KC423222AZT, D4T, 3TC, TDFNVP, EFVM41L, D67N, M184V, L210W, T215YK103N, V179E, K238TE6K, K20R, V35T, T39E, E44D, S48T, V60I, V118I, K122E, D123N, I135T, E138A, K173T, Q174K, D177N, I178L, T200A, E203K, Q207E, H208Y, R211K, K223E, P243Q, V245Q, E248D, D250EC
 5061863KC423465TDF, 3TCEFVL74I, M184VK103N, V179ET7P, V35T, T39DG, S48T, E53D, V60I, K122E, D123N, S162C, K173A, Q174K, D177E, I178L, T200A, Q207N, R211K, V245Q, E248Q, D250EC
 819508KC424102D4T, 3TCEFVM184VK103N, V108VI, V179EV35T, E36A, T39D, E40D, S48T, V60I, K82R, V90I, K122E, D123S, I135IL, E138A, T139S, I142V, S162Y, K173A, Q174K, D177E, I178IM, T200A, Q207R, R211K, V245QC
 12592KC424157D4T, 3TCEFVM184VK103N, V179E, Y181CK20R, E28A, V35T, T39E, S48T, K122E, K173A, D177G, T200A, Q207E, R211K, L228R, V245QC
 1142590KC423751D4T, 3TCEFVM184VK103N, V108VI, V179EP4S, V35T, T39E, S48T, K122E, D123S, E138A, A158S, K173T, Q174R, E194A, G196E, T200A, Q207E, R211RKNS, V245Q, E248DC
 7022940KC423902AZT, D4T, 3TC, TDFNVP, EFVK65R, T69~K103HN, V179E, Y181C, Y188HV35T, E36A, T39D, S48T, S68N, K102R, D121H, K122E, S162A, K173T, Q174K, T200A, Q207E, R211K, V245E, D250EC
 185648KC424199D4T, 3TCEFVM184V, T215VK101H, V179E, Y188LV35T, E36A, T39D, S48T, K122E, D123N, E138A, V148VA, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, P243T, V245Q, E248DC
  1219KC422970D4T, 3TCEFVM184V, T215FK101H, V179E, Y188LV35T, E36A, T39D, S48T, K49R, K122E, D123N, I135IT, E138A, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LC
 1751265KC423013TDF, 3TCEFVA62V, M184VV106M, V179E, F227LT27S, I31R, V35I, K122E, K173A, D177E, I178L, I180L, T200A, Q207D, R211K, V245QC
 15132674KC423778TDF, 3TCEFVK70KQ, L74LI, M184VV106M, V179E, G190GA, F227FLV35T, T39E, S48T, L109I, K122E, D123N, K173T, Q174K, D177E, T200A, Q207E, R211K, V245QC
Steegen (2014)12ZAKS24212ZAKS242KJ176521D4T, 3TCNVPM184VV179E, Y181CK20R, V35T, E36A, T39E, S48T, K103R, K122E, K166R, D177N, T200A, Q207EK, F214L, V245Q, A272P, Q278H, T286A, E291D, V292I, V317I, G335DC
 10ZAKS04710ZAKS047KJ176329D4T, 3TCEFVM41L, D67N, M184V, T215FV106M, V179E, G190GA, F227LK20KR, V35T, T39E, S48T, V60I, L109I, K122E, T139K, I142V, K173E, Q174R, D177G, T200E, E203EK, Q207E, H208Y, R211K, K223KHNQ, V245Q, A272P, E291D, V292I, I293VC
 12ZAKS20312ZAKS203KJ176483ABC, 3TC, D4TEFVL74V, Y115F, M184VV106M, V179E, F227LV35T, T39E, S48T, W88S, K122E, D123N, E138A, K173I, Q174K, D177N, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, I274IV, K275R, K277R, Q278H, K281KR, T286A, E291D, V292VI, I293V, I329V, G335D, R356K, R358K, G359S, T369TA, A371V, I375V, T377M, K390R, E396D, A400T, E404DC