<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation V179E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 21
Patients 53
Isolates 55
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Seoighe (2007)PL17206_PL172V2EF382106NoneNVP V179EK30I, V35T, T39K, V60I, I135IT, A158S, S162Y, K173T, Q174K, D177E, T200A, Q207E, R211RK, F214FL, V245VA, K249R, S251H, A272P, E291D, V292I, I293V, P294PTC
Waleria-Aleixo (2008)08PR05038608PR050386FJ591411NRTINNRTID67N, K70R, M184V, K219QV179EK20R, E28K, K32E, V35T, E36A, T39E, K43R, S48T, V60I, K102Q, D121Y, K122E, K166R, T200A, E203K, Q207E, R211K, F214L, P243PS, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, S322T, G335DC
 08PR05028908PR050289FJ591317NRTINNRTID67N, K70R, M184V, K219QK103N, V179E, P225HV35T, T39D, S48T, E53ED, V60I, T69N, K122E, D123GS, I135L, E138A, K173A, Q197K, T200A, Q207A, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, K331N, G335DC
Wallis (2009)22803932280393 AZT, 3TCEFVM184VV106M, V179EK20R, V35T, T39E, S48T, K49R, V60I, E138A, T139I, K173T, Q174K, T200A, I202IV, Q207E, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, P321T, D324E, I326IMC
 23674142367414 AZT, 3TCEFVM41L, D67N, T69D, L74V, M184V, L210W, T215YK103N, V179E, M230LS3C, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, V111VIM, P119PL, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, D324EC
 TJC2367640TJC2367640 D4T, 3TCEFVV75I, M184VV106M, V179EV8VI, K11Q, V35T, T39E, S48T, K122E, D123N, I132L, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, L283I, T286V, E291D, V292I, I293VC
 23567552356755 AZT, 3TCEFVM41L, D67N, T69D, L74V, M184V, L210W, T215YK103N, V179E, M230LS3SC, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, V111VIM, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, L310LQ, D324EC
El-Khatib (2010)Pat07510ZA_SAVE2491HQ012353D4T, 3TCEFVA62AV, M184VV106M, V179E, F227FLV35T, T39E, S48T, E53D, V118I, K122E, D123N, I135T, E138A, Q145H, K173T, Q174R, T200A, Q207G, R211K, F214L, V245Q, E248DC
Hamers (2012)CP076303944CP076303944JQ480292TDF, FTCEFVK65R, M184VV106M, V179EV8VI, I31L, V35T, E36A, T39E, S48T, E53D, K122E, D123N, S162H, K173T, Q174R, D177E, T200A, I202V, Q207E, R211K, V245L, K249Q, D250E, A272P, K277GR, E291D, V292I, I293VC
Sunpath (2013)CAS043CAS043 TDF, 3TCEFVD67DN, M184IV108I, V179E, Y181CK20R, V35T, E36A, T39K, K43E, S48T, V60I, V90VI, K102Q, K103R, K122E, D123N, Q174K, D177E, V189VI, T200A, R211K, F214L, H221HY, V245Q, A272P, A288S, E291D, V292I, I293VC
Van Zyl (2013)O1751265KC423013TDF, 3TCEFVA62V, M184VV106M, V179E, F227LT27S, I31R, V35I, K122E, K173A, D177E, I178L, I180L, T200A, Q207D, R211K, V245QC
 303107.ZA.GT295KC424102D4T, 3TCEFVM184VK103N, V108VI, V179EV35T, E36A, T39D, E40D, S48T, V60I, K82R, V90I, K122E, D123S, I135IL, E138A, T139S, I142V, S162Y, K173A, Q174K, D177E, I178IM, T200A, Q207R, R211K, V245QC
 225912.ZA.GT2237KC423902D4T, 3TC, TDFEFVK65R, T69~K103HN, V179E, Y181C, Y188HV35T, E36A, T39D, S48T, S68N, K102R, D121H, K122E, S162A, K173T, Q174K, T200A, Q207E, R211K, V245E, D250EC
 259211.ZA.GT2017KC423751D4T, 3TCEFVM184VK103N, V108VI, V179EP4S, V35T, T39E, S48T, K122E, D123S, E138A, A158S, K173T, Q174R, E194A, G196E, T200A, Q207E, R211RKNS, V245Q, E248DC
 12508.ZA.GT386KC424157D4T, 3TCEFVM184VK103N, V179E, Y181CK20R, E28A, V35T, T39E, S48T, K122E, K173A, D177G, T200A, Q207E, R211K, L228R, V245QC
 408212.ZA.GT2071KC423778TDF, 3TCEFVK70KQ, L74LI, M184VV106M, V179E, G190GA, F227FLV35T, T39E, S48T, L109I, K122E, D123N, K173T, Q174K, D177E, T200A, Q207E, R211K, V245QC
 165209.ZA.GT638KC424199D4T, 3TCEFVM184V, T215VK101H, V179E, Y188LV35T, E36A, T39D, S48T, K122E, D123N, E138A, V148VA, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, P243T, V245Q, E248DC
  10.ZA.GT1120KC422970D4T, 3TCEFVM184V, T215FK101H, V179E, Y188LV35T, E36A, T39D, S48T, K49R, K122E, D123N, I135IT, E138A, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LC
 203811.ZA.GT1672KC423465TDF, 3TCEFVL74I, M184VK103N, V179ET7P, V35T, T39DG, S48T, E53D, V60I, K122E, D123N, S162C, K173A, Q174K, D177E, I178L, T200A, Q207N, R211K, V245Q, E248Q, D250EC
Steegen (2014)12ZAKS24212ZAKS242KJ176521D4T, 3TCNVPM184VV179E, Y181CK20R, V35T, E36A, T39E, S48T, K103R, K122E, K166R, D177N, T200A, Q207EK, F214L, V245Q, A272P, Q278H, T286A, E291D, V292I, V317I, G335DC
 10ZAKS04710ZAKS047KJ176329D4T, 3TCEFVM41L, D67N, M184V, T215FV106M, V179E, G190GA, F227LK20KR, V35T, T39E, S48T, V60I, L109I, K122E, T139K, I142V, K173E, Q174R, D177G, T200E, E203EK, Q207E, H208Y, R211K, K223KHNQ, V245Q, A272P, E291D, V292I, I293VC
 12ZAKS20312ZAKS203KJ176483ABC, 3TC, D4TEFVL74V, Y115F, M184VV106M, V179E, F227LV35T, T39E, S48T, W88S, K122E, D123N, E138A, K173I, Q174K, D177N, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, I274IV, K275R, K277R, Q278H, K281KR, T286A, E291D, V292VI, I293V, I329V, G335D, R356K, R358K, G359S, T369TA, A371V, I375V, T377M, K390R, E396D, A400T, E404DC
Kaleebu (2015)MBL-0043UGA-MBL-0043-2012 TDF, 3TCEFVA62V, K65R, M184VV106M, V179E, F227FLV35I, E36A, T39E, S68N, K122E, D123G, I135M, K173T, Q174K, D177N, G196E, T200A, Q207E, R211K, V245Q, E248D, D250T, A272P, L283I, T286A, E291D, V292I, I293VC
 MBL-0030UGA-MBL-0030-2012 TDF, 3TCNVP V179E, Y188YFHLV35T, T39E, K43KR, K49KR, K122E, D123N, I142V, A158S, K173T, Q174K, D177E, I178M, T200A, I202V, Q207E, P243T, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, V317TC
Saravanan (2015)CTLA149CTLA149KP993752NRTINNRTIK70E, M184VV106M, V179E, F227LV35T, E36A, T39D, S48ST, V60I, V90VI, D121H, K122E, I135R, K173AT, D177E, T200A, Q207EC
Seu (2015)ZM.HIVDRM.33ZM.HIVDRM.33KP995643TDF, FTCNVPD67N, K70R, V75M, M184V, K219QV106M, V179E, F227LK20R, V35T, T39E, S48T, V60I, K64Y, D121C, K122E, E138A, K173T, Q174K, T200A, I202V, E203K, Q207E, R211K, F214L, H221Y, L228H, D250E, A272P, K277R, T286TA, E291D, V292IC
Skhosana (2015)10ZALS00310ZALS003KM115813D4T, 3TCEFVM184VK103N, V179E, P225PHK20R, V35T, E36EA, T39E, K102Q, K122E, D123S, I135IT, S162SC, K166KR, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293VC
Dinesha (2016)T8T8KX275052TDF, FTCEFVM41L, K65R, V75M, Y115F, M184VV106M, V179E, F227LV35T, T39D, E42D, K43HP, E44D, K46W, S48T, E53D, V60I, S68N, W88C, D121H, K122E, I135T, I142V, S162A, K166KR, K173A, Q174QK, D177E, Q197L, T200A, Q207E, R211KC
Lam (2016)1301100113011001KR868122D4T, 3TCNVPD67N, K70R, M184V, K219QA98G, V179E, G190AV35T, T39A, S48T, V60I, I135L, K166R, K173A, D177E, T200A, Q207V, R211K, D218E, D250E, S251H, A272S, K277R, L283LI, T286A, E291D, V292I, I293V, V314A, S322TC
 9902200299022002KR868103D4T, 3TCEFVM184VV106M, V179EE6D, K20R, I31L, V35T, T39E, S48T, V60I, K122E, D123N, K173A, Q174K, T200A, Q207E, V245L, A272P, Q278H, K281R, E291D, V292I, I293V, G335DC
Neogi (2016)103013.ZA.EC764KT592893TDF, 3TCNVPM41ML, K65KR, M184V, T215TSA98G, K103N, V179EK20R, V35IT, T39S, K46KQ, S48T, S68SG, K122E, D123GS, I135IL, E138EG, I142V, K173A, Q174K, D177E, I178L, T200TA, Q207E, R211K, V245Q, E248DC
 553713.ZA.EC618KT592796TDF, 3TCEFVK70E, M184V, K219RK103N, V179E, P225HK20R, V35T, E36A, T39D, S48T, K122E, D123S, K173A, D177N, T200A, Q207D, R211K, L228R, V245EC
 549913.ZA.EC528KT592735TDF, 3TCEFVK70E, M184V, K219RK103N, V179E, P225HK20R, V35T, E36A, T39D, S48T, K122E, D123S, K173A, D177N, T200A, Q207D, R211K, V245E, D250EC
Steegen (2016)GFNWB029GFNWB029KU128167TDF, FTCEFVK70E, Y115YF, M184VK103N, V179E, Y181CP4S, V35T, E36A, T39E, S48T, K122E, D123N, D177G, T200A, Q207E, L228R, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, D324DE, I329L, Q334H, G335D, R356K, G359T, T369A, T377L, K390R, A400T, E404DC
 GFNWB021GFNWB021KU128028TDF, 3TCEFVK70Q, M184V, T215TIA98G, V179E, Y188LK20R, V35T, E36A, T39E, S48T, V60I, V106I, K122E, D123N, K166KR, K173T, N175NY, T200A, R206RK, Q207E, F214L, V245H, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, S322T, Q334H, G335D, R356K, G359T, T369S, T377M, K390R, E396D, A400T, E404DC
 GFKZB382GFKZB382KU128303D4T, 3TC, TDF, FTCEFVM184VK103N, V179EK11KR, T27S, V35T, E36A, T39E, S48T, V60I, K122E, D123N, I135K, K173A, Q174K, D177E, I195L, T200A, Q207G, R211Q, V245Q, K249KR, D250E, A272P, K277KR, E291D, V292I, I293VC
 GFKZB168GFKZB168KU128068TDF, 3TC, FTCEFVK65R, T69~, Y115FV106M, V179E, Y181C, G190AK20KR, V35T, T39D, S48T, V60I, V90I, D121H, K122E, K173T, Q174K, D177E, E194K, T200A, I202V, Q207E, R211K, F214L, V245Q, A272P, K277Q, K281R, T286A, E291D, V292I, I293V, E297K, I329L, R356K, G359T, T377L, K390R, A400T, E404D, V435LC
 GFKZB090GFKZB090KU127959TDF, 3TCEFVA62V, K65R, L74I, M184VV106M, V179E, F227LV35T, E36A, T39E, S48T, S68N, K122E, D123G, I135L, E138G, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I329L, Q334H, G335D, R356K, G359T, T369A, T377I, K390R, A400T, E404DC
Steegen (2016)ZA13GFGPC024ZA13GFGPC024KU252908NRTINNRTIM41L, D67N, K70R, M184V, T215Y, K219QV106M, V179EK20KR, V35T, T39E, S48T, V60I, V118I, K122E, D123N, I135T, E138A, K173T, Q174X, N175NY, T200A, I202IV, Q207E, R211K, F214L, Y232H, V245Q, A272P, K277KR, Q278N, K281KR, L283I, T286V, E291D, V292I, I293V, Q334S, G335D, R356K, G359T, T377R, S379C, K390R, A400T, E404DC
 ZA13GFFSC012ZA13GFFSC012KU252940NRTINNRTIM184VV106M, V179E, F227LK20R, V35T, E36A, T39E, S48T, K49R, W88C, K122E, S162N, E169A, K173A, D177E, I178L, G196T, T200A, E203K, Q207E, F214L, D237NC
 ZA14GFLPC010ZA14GFLPC010KU253144NRTINNRTID67N, K70R, M184MV, T215I, K219EK103N, V179E, G190AK20R, V35T, T39E, S48T, V60I, T69N, K122E, D123S, I135T, E138A, T139TA, S162C, Q174E, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, K366KR, T369AC
 ZA14GFMPC032ZA14GFMPC032KU253194NRTINNRTIM41L, M184V, T215Y, N348IV179E, Y188LV35K, T39E, E40D, K173A, Q174K, N175Y, T200E, Q207E, R211K, V245K, E248D, A272P, Q278Y, T286A, E291D, V292I, I293V, K311KE, Q334QH, G335D, A355T, R356K, M357R, G359T, K366R, A376S, T377M, K390R, E396D, A400I, E404D, E432DC
Karade (2017)SK_IF_16-206SK_IF_16-206KY787068NRTINNRTIK70E, Y115F, M184VV106M, V179EV35T, T39N, S48T, V60I, A98AS, D121Y, K122E, I135T, S162Y, K173T, D177E, T200A, Q207K, R211T, L228Q, Y232H, V245QC
Kityo (2017)2840728407KY061381NRTINNRTIA62V, D67N, K70G, V75I, F77L, F116Y, Q151M, M184VV179E, G190AK20R, V35T, T39E, E40D, W88S, K122E, D123N, K173R, I178F, T200A, Q207E, R211K, F214L, V245L, A272P, K275Q, V276T, K277R, Q278H, T286A, E291D, V292I, I293V, P294AC
 8353783537KY062091NRTINNRTID67N, K70R, M184V, T215Y, K219EV179E, Y181CS48T, V60I, T69TN, K103R, K122E, D123GS, I135IATV, K173T, D177E, T200A, Q207EC
 8298182981KY061544NRTINNRTIA62V, D67N, K70KEGR, V75VI, F77L, F116FY, Q151QKLM, M184V, T215TNSYA98AG, V179E, G190AW88*S, K122E, D123N, I135IL, K173*RST, D177DE, I178IL, T200A, I202IV, Q207ADE, R211RK, F214FLC
Posada Cespedes (2017)98214.ZA.WC515KX544767TDF, FTCEFVL74V, M184VK103KN, V106VM, V179E, M230LV35T, T39E, S48T, K102Q, K122E, D123N, S162C, K173V, Q174K, G196E, T200A, Q207E, V245Q, E248DC
 51612.ZA.EC477KX541928D4T, 3TCEFVM184VV106M, V179E, F227LE6D, V35R, T39E, S48T, K122E, D123S, I135L, K173T, D177N, I195K, G196E, T200A, E203EK, Q207EC
 708812.ZA.EC392KX541851TDF, 3TCEFVK65R, M184IK103N, V179E, M230LE6K, V35T, E36A, T39E, S48T, E53D, K122E, D123N, S162H, K173A, D177E, I178M, G196E, T200A, Q207E, K238X, V245QC
 471214.ZA.GT3815KY205506TDF, 3TCNVPK65R, Y115F, M184VV179E, Y181C, G190AK20KR, V35T, T39E, S48T, E53D, V60VI, K64R, K102R, K103R, D121DH, K122E, D123S, K173A, Q174K, D177E, T200A, E203D, Q207E, R211K, F214L, V245QC
 478014.ZA.GT3882KY205522TDF, 3TCEFVA62V, K65R, Y115F, M184VV106M, V179E, Y181C, F227LE6EK, V35T, E36A, T39E, W88S, K102Q, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, K238R, V245QC
 532311.ZA.EC121KX541003NRTINNRTIM184VK103N, V179EP4S, E6EK, V35T, T39E, S48T, E53D, V60I, V118I, K122E, D123N, I135IL, E138A, T200A, Q207E, R211K, F214L, K238RC
 314610.ZA.GT1243 AZT, 3TC, DDI, D4TNVPM184V, T215TNSYK103N, V179EP4PS, V35T, E36A, T39E, S48T, K122E, D123S, E138Q, S162C, K173A, T200A, E203Q, Q207D, R211K, V245Q, D250DEC
 203814.ZA.GT3341KX544226TDF, 3TCEFVM184VK103N, V179EK11R, E28K, V35T, T39D, S48T, E53D, V60I, K122E, D123N, I135T, K173A, Q174K, D177E, I178L, T200A, Q207N, R211K, V245Q, D250EC
Rhee (2017)11391139KY353494TDF, 3TCEFV K103KN, V106VM, V108VI, V179EK20KR, V35T, E36A, T39D, S48T, V60VI, V90VI, K122E, D123S, I135T, E138A, K166R, K173A, D177E, T200A, E204K, Q207D, R211KC

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