<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation V179D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK1026TK1026 ABC, AZT, 3TCNoneY115F, M184V, T215FE138K, V179DE6D, P14Q, V35T, E36A, T39D, I47IT, S48T, A98S, K122E, D123N, K173A, D177K, T200A, Q207E, R211K, F214L, K223KQ, E224EK, Y232YC, K238KE, I244IEKV, V245Q, A272P, T286V, E291D, V292I, I293VC
 TK3032TK3032 AZT, 3TC, D4TNoneM41L, M184V, T215FV179DV8I, K20R, V35T, E36A, T39E, S48T, V118I, K122E, D123N, I135T, S162T, E169Q, K173T, Q174K, T200A, Q207E, R211K, F214L, P243T, V245Q, E248D, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, D324E, I329LC
Van Zyl (2013)303807.ZA.GT081KC424144D4T, DDINone V179DV35T, E36A, T39E, S48T, V60I, K103KR, S162C, K173A, Q174K, D177E, T200E, Q207E, V245Q, K275Q, E291D, V292I, I293V, P294PT, Q334E, G335DC
 706112.ZA.EC201KC423885AZT, 3TCNone V179DV35T, T39E, S48T, K122E, D123S, K173IM, Q174K, T200A, Q207E, V245Q, E248D, D250EC
 54811.ZA.EC064KC423577AZT, 3TCNoneM184VV179DK20R, V35T, E36A, T39E, S48T, W88C, K102R, K103R, V118I, K122E, D123N, I135L, E138A, T139A, S162C, Q174K, T200A, Q207E, R211I, F214LC
 383510.ZA.GT1257KC423082D4T, 3TCNoneM184VV179DV35T, E36A, T39E, S48T, K122E, D123A, I142IV, K173T, T200A, I202V, Q207N, F214L, V245Q, D250EC
 280306.ZA.GT037KC424098AZT, DDINone V179DP4S, V8I, V35T, T39E, S48T, K102Q, K103R, K122E, I159IV, K173A, D177E, G196T, T200A, Q207E, R211K, L228I, V245EK, E248D, D250E, Q258P, A272P, K277N, Q278R, E291D, I293V, P294T, S322SL, Q334N, G335D, Q340Q*C
Steegen (2014)12ZAKS24712ZAKS247KJ176526D4T, 3TCNone V179DE6N, V35T, T39E, S48T, V118I, K122E, D123N, E138A, T139V, K173T, Q174K, D177N, T200E, Q207K, R211E, F214L, V245Q, E248D, A272P, G273R, K275R, Q278Y, K281R, E291D, V292I, I293V, A304E, P313T, Q334N, G335D, Y342F, Q343KC
Posada Cespedes (2017)575415.ZA.WC605 AZT, 3TCNoneM41L, M184VV179DV35T, T39A, S48T, E53D, K103R, K122P, I135X, K173T, Q174K, D177E, T200A, Q207D, R211K, F214L, V245QC
 530511.ZA.EC091KX540976AZT, DDINone V179DK20R, V35T, T39E, S48T, V60VI, K103R, K122E, D123N, I135IT, S162C, I178IL, T200A, E204K, Q207E, R211K, F214L, V245QC
 515815.ZA.GT4272 AZT, 3TC, DDINone V179DV35T, T39E, S48T, K122E, D123S, K173AE, Q174K, D177E, G196T, T200A, E204Q, Q207E, R211K, V245Q, E248DC
 277207.ZA.GT342 AZT, DDINone V179DV35T, T39N, S48T, V60I, K103R, D121N, K122E, K173T, Q174R, T200A, Q207AE, R211K, F214L, V245Q, D250EC
 575315.ZA.EC1666 AZT, 3TCNoneA62V, M184VV179DE6EK, K11Q, E28K, K32E, V35T, E36A, T39E, K103R, K122E, D123G, I135L, K173A, Q174R, D177E, I178M, T200A, E203D, Q207E, V245QC
 279112.ZA.GT2423 AZT, 3TCNone V179DK20R, V35T, T39G, S48T, K122E, D123S, K173A, Q174R, D177G, T200A, Q207E, R211K, F214L, V245QC