<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation V179D
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 18
Patients 61
Isolates 64
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2005)ESH3078ESH3078AY756838NoneNVP V179D, Y181YCE6K, V35T, E36A, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, Q207E, R211K, V245Q, D250N, A272P, K277R, T286A, E291D, V292I, K311RC
Non-B Workgroup (2005)SA76_DR18SA76_DR18AY901710D4T, DDIEFVD67DN, K70KRV106M, V179DE6EK, K20KR, V35T, T39E, S48IT, G51GW, K66E, L100LV, K102Q, K103R, K122E, I135IM, I142IV, K173T, T200A, E204Q, Q207E, F214L, V245Q, A272P, T286V, V292I, I293V, G333E, Q334HC
 IL642IL642AY901782AZT, 3TC, D4T, DDINVP V179D, Y188LT39E, K122E, D123S, S162A, K173T, D177E, T200A, Q207E, R211K, V245QC
 TK3015TK3015a AZT, 3TC, DDC, ABCEFVM41L, D67N, L210W, T215YV106M, V179DV35M, T39D, E44D, V118I, K122E, I135L, K173A, Q174K, N175Y, D177E, E194K, G196E, T200A, I202V, Q207E, R211K, V245Q, D250E, I257V, A272S, K281R, T286A, E291D, V292I, I293V, H315X, I329XC
  TK3015b AZT, 3TC, DDC, ABCEFVM41L, D67N, L210W, T215YV106M, V179DE6EK, V35M, T39D, E44D, V118I, K122E, I135L, K173A, Q174K, N175Y, D177E, E194K, G196E, T200A, I202V, Q207E, R211K, V245Q, D250E, I257IV, A272S, K281KR, T286A, E291D, V292I, I293V, H315FC
  TK3015c AZT, 3TC, DDC, ABC, TDFEFV, NVPM41L, D67N, L210W, T215Y, K219RV106M, V179D, F227LE6K, V35M, T39D, E44D, K102KR, V118I, K122E, I135L, K173A, Q174KR, N175NY, D177E, V189VI, E194K, G196E, T200A, I202V, Q207E, R211K, V245Q, D250E, A272S, K281KR, T286A, E291D, V292I, I293V, H315FC
 PL4999292981 AZT, 3TCEFVM41L, V75L, M184VV106M, V179DT27A, V35T, T39E, K103R, K122E, D123S, I135T, K173A, T200A, Q207E, R211K, F214L, V245Q, K277R, L283LI, T286TA, V292VI, I293V, P294T, E297D, I326VC
 PL5249699430 3TC, D4T, TDF, DDIEFVA62AV, K65RV106M, V179DE6K, V8I, V35T, E36A, T39E, S48T, K102R, K122E, K173T, D177E, T200A, Q207E, F214L, V245T, A272P, K277R, K281R, E291D, V292I, I293VC
Baxter (2006)48-14071407-30410DQ877803NRTINNRTIM41L, D67N, V75VL, L210W, T215Y, K219RV106M, V179D, F227LE6K, V35M, T39D, E44D, V118I, K122E, I135L, K173AT, Q174KR, N175Y, D177DE, E194K, G196E, T200A, I202V, Q207E, R211K, V245Q, D250E, A272S, K281R, T286A, E291D, V292I, I293V, H315F, Q334H, G335D, R356K, G359T, A371V, T377M, T386I, K390RC
Doualla-Bell (2006)Pt23FDB_Pt23EF434886AZT, 3TC, D4T, DDINVPM41L, D67N, T69D, V75T, T215YV108I, V179D, Y181CK20R, V35T, T39D, E44D, D121C, K122E, I135T, E138A, K173T, D177E, I178L, V189I, T200A, E203D, E204K, Q207D, R211K, H221Y, P243S, V245Q, A272P, E291D, V292I, I293VC
Kurle (2007)NVP-11-M2DQ838755NoneNVP V179DE28K, K32E, V35T, E36A, T39N, S48T, V60I, D121C, K122E, I135V, S162C, E169K, K173E, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, K311R, G335D, R356K, G359T, T377M, K390R, A400T, E404DC
 NVP-3838-M2DQ838781NoneNVP V179DV35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359TC
Novitsky (2007)16461646_3858EF026222AZT, DDINNRTI V179DP4S, V35T, E36A, T39E, S48ST, K103KR, K122E, D123S, E138A, K173A, Q174K, T200A, I202V, Q207E, R211K, F214L, L228LH, V245E, A272P, K277R, A288T, E291D, V292I, I293V, H315FC
Seoighe (2007)CHB35306_C353EF381905NoneNVP K103KN, V106VA, V179DV35T, E36A, T39E, E40D, S48T, K104R, V118I, K122E, D123S, E138A, T139A, T165I, K173T, Q174K, T200A, I202V, Q207G, R211K, F214L, V245Q, E248D, A272P, T286TA, E291D, V292I, I293V, L295LVC
 KEH10106_K101EF381962NoneNVP V179DV10VL, E29D, V35T, T39E, S48T, V60I, K122E, D123S, I135T, K166R, K173A, Q174R, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 PL5506_PL55V2EF382192NoneNVP V179DV35K, T39E, S48T, P52PS, K104R, K122E, D123S, K173M, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248N, A272P, I274IV, K275R, Q278N, T286A, E291D, V292I, I293V, P294TC
Marconi (2008)ICH13ICH13EU308005D4T, AZT, 3TCEFVV75I, M184VV106M, V179DS48T, K122E, I132IL, I135V, T139K, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, F214FL, V245QC
 ICH14ICH014EU308006D4T, AZT, 3TCEFVM41L, V75I, M184V, T215YV106M, V179DS48T, K103R, I132L, I135V, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245QC
 ICH30ICH030EU308020D4T, 3TCEFVM184VV106M, V179D, M230LS48T, V60I, V118I, K122E, D123N, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245QC
 SW007sw007EU308025D4T, 3TCEFVM184VV106M, V179DS48T, K122E, D123S, K173A, Q174R, D177E, G196M, T200A, Q207E, V245QC
 SW039sw039EU308052AZT, 3TC, DDIEFV V106M, V179D, K238TE40D, S48T, V60I, D121H, K122E, E138A, I142ST, K173A, Q174K, D177E, T200A, Q207E, F214L, V245QC
 SW043sw043EU308056D4T, DDI, AZT, 3TCEFVM41L, A62V, M184VV106M, V179D, F227LS48T, V60I, K103R, K122E, D123S, I135V, K173V, Q174K, D177E, T200A, I202V, Q207E, F214FL, L228R, V245QC
 SW069SW069EU308080D4T, 3TCEFVM184VV106M, V179DE40D, V60I, K122E, D123G, K173A, Q174R, T200A, I202V, Q207E, R211K, V245QC
 SW070SW070EU308081D4T, 3TC, AZTEFVD67N, K70RE138K, V179DS48T, V60I, K103R, V106I, K122E, D123N, I135M, K173A, Q174K, D177E, T200A, Q207D, R211K, F214L, V245QC
 SW080SW080EU308090D4T, 3TCEFVM184VV106M, V179DS48T, K102R, K103R, K122E, D123N, I167IF, K173T, D177E, T200A, Q207E, V245QC
 SW085SW085EU308095D4T, 3TCEFVM184VV179D, Y188LS48T, K122E, D123G, A158AT, T165I, K173A, D177E, T200A, Q207A, R211K, V245QC
 SW102SW0102EU308110D4T, 3TCEFVK70R, M184VV106M, V179DS48T, S68G, V90I, K103R, D121Y, K122E, D123G, S162C, K173A, D177E, T200A, E203EK, Q207E, R211KC
Pillay (2008)DR69DR69AY589918D4T, DDIEFVK65R, D67NV106M, V179D, Y188CV35T, T39D, S48T, K122E, D123S, K173A, D177E, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, I293V, H315HQC
 DR1802ZA.DR18AY589879D4T, DDIEFVD67DN, K70KRV106M, V179DE6EK, K20KR, V35T, T39E, S48IT, G51GW, K66E, L100LV, K102Q, K103R, K122E, I135IM, I142IV, K173T, T200A, E204Q, Q207E, F214L, V245Q, A272P, T286V, V292I, I293V, G333E, Q334HC
 DR8403ZA.DR84AY589927D4T, DDIEFV V179D, Y188L, G190AV8I, V35K, T39E, S48E, V60I, K103R, I159V, K173T, Q174K, T200A, Q207E, R211K, V245Q, D250E, A272P, K277T, K281KR, T286A, V292I, I293V, E297K, L301FC
Hoffmann (2009)pat055MD66281 AZT, 3TCEFV V179DV35T, E36A, T39E, S48T, K103R, K122E, D123S, T139A, K173R, Q174K, D177N, T200E, Q207E, R211K, F214L, V245Q, A272PC
Hosseinipour (2009)94019401GQ228334D4T, 3TCNVPM41L, K65RV179D, Y181CT39E, E44D, K122E, S162C, K173T, D177E, I178L, T200A, Q207D, R211K, V245QC
 94549454GQ228369D4T, 3TCNVPM184V, T215FV106M, V179D, M230LT39E, S48T, K103R, L109I, K122E, D123N, K173A, Q174R, T200A, I202IV, Q207R, R211EC
 77257725GQ228373D4T, 3TCNVPK65R, Q151M, M184VV179D, Y181CT39E, E53D, S68G, K103R, V118I, K122E, D123S, I135T, T139A, S162D, K173T, T200A, Q207A, R211K, F214L, K223KQ, V245QC
Kassaye (2009)TCDD-08TC08_2004FJ445726D4T, 3TCEFVM184V, T215FV179D, M230LV8I, K20R, V35K, T39E, S48T, V60I, K103R, K173T, D177E, T200A, Q207EC
Rey (2009)88w4 TDF, 3TCNVP V179DT39E, S48T, K122E, D123S, K173T, Q174K, T200A, Q207E, F214L, K238R, V245QC
  8w12 TDF, 3TCNVPK65RV179D, G190AT39E, S48T, K122E, D123G, K173T, Q174K, T200A, Q207E, F214L, L228Q, K238R, V245QC
Wallis (2009)GT00408301GT00408301 D4T, 3TCEFVK70KR, M184VV106M, V179DE6EK, V35T, T39N, S48T, K103R, K122E, D123S, T139A, K173T, T200A, Q207E, R211RK, V245Q, A272P, K277KR, V292I, I293VC
 TJC2394973TJC2394973 D4T, 3TCEFVM184VV106M, V179D, M230LE6K, K11N, K32R, V35T, T39E, S48T, W88S, K103R, K122E, D123N, E138A, K173T, Q174K, T200A, I202V, E204Q, Q207E, R211K, F214L, V245Q, E248D, D250A, A272P, K275R, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, I329L, Q334EC
 TJC2402512TJC2402512 D4T, 3TCEFVM184VV106M, V179D, F227LP4H, K20R, V35T, E36A, T39E, K122E, D123S, A158S, K173A, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K277T, K281R, T286A, E291D, V292I, I293VC
 TJC2382138TJC2382138 D4T, 3TCEFVL74V, M184V, T215FV106M, V179D, M230LP4S, V35T, E36A, T39E, S48T, K104R, K122E, D123N, S162C, K173A, Q174K, D177G, T200A, Q207E, R211K, V245Q, E248D, A272P, Q278H, E291D, V292I, I293V, I329VC
 GT00237954GT00237954 D4T, 3TCEFVD67N, K70R, V75I, M184V, K219QV106M, V179DV35R, T39D, S48T, V60I, K102KR, K103KR, K104KR, K122E, D123N, I132L, K173Q, Q174G, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, A272K, R284K, T286A, E291D, V292I, I293V, P294T, E308K, L310C, S322T, Q334EC
 GT00000751GT00000751 D4T, 3TCEFVA62V, M184VV106M, V179DP4S, V35T, T39E, S48T, K103R, K104KR, K122E, D123S, I135T, S162C, K173T, Q174K, N175Y, T200A, K201KR, Q207E, R211K, F214L, D237N, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, E312QC
 23605072360507 D4T, 3TCEFVM184VV106M, V179DV35T, E36EA, T39E, K102KR, K103R, D123S, I135L, P157PR, D177E, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, E308EK, I309IV, L310XC
 23354852335485 D4T, 3TCEFV V106M, V179DK20R, V35T, T39E, S48T, S105L, K122E, D123N, T139S, I142A, K173R, Q174K, G196E, T200A, E204Q, Q207E, F214L, V245Q, D250E, S251N, A272P, K277R, T286A, E291D, V292I, I293V, E308GR, K311R, Q334EC
 TJC2429706TJC2429706 D4T, 3TCEFVM41L, D67N, K70R, V75M, M184V, L210W, T215F, K219EV106M, V179D, F227LV35T, E36A, T39E, V60I, K122E, D123G, I132V, K173T, D177E, I178L, T200A, E203EK, Q207D, R211K, H221Y, V245Q, K281R, L283I, T286A, E291D, V292I, I293VC
 TJC2411483TJC2411483 D4T, 3TCEFVM184VV179D, Y188LE6K, K11Q, K20R, V35T, T39E, V118I, K122E, D123G, K173T, Q174R, D177E, T200A, Q207E, R211Q, F214L, V245Q, A272P, K277R, E291D, V292I, I293VC
 TJC2389108TJC2389108 AZT, 3TCEFVK70KR, M184VV106M, V179DP4T, K20R, E28A, V35T, T39EK, S48T, V60I, K103R, K122E, D123S, I132V, A158S, R172S, K173T, Q174K, D177E, G196E, T200A, Q207E, F214L, V245Q, A272P, L283I, E291D, V292I, I293V, G333E, Q334HC
El-Khatib (2010)Pat07310ZA_SAVE2474HQ012351D4T, 3TCEFVM184VV106M, V179D, F227FLE6D, K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, D177E, V189VI, Q197K, T200E, I202IV, Q207E, R211K, F214FL, V245M, E248D, D250E, S251C, I257LC
 Pat11111ZA_SAVE2266JF960561NRTI, AZT, DDINNRTI V106M, V179DP4S, V35T, E36A, T39E, E40D, S48T, K103R, K122E, D123S, I159V, E169D, K173A, Q174K, D177E, G196M, T200A, I202V, Q207E, F214L, K238R, V245Q, E248D, A272P, K275RC
Green (2011)707PKE25F707PKE25FHM623514D4T, 3TCEFVM41ML, D67DN, K70KR, M184V, T215TNSY, K219KQV179D, Y188LE28A, V35T, T39E, S48T, V60I, K103R, K122E, D123G, I135IATV, I142T, K173A, D177DE, I178L, T200A, Q207E, R211RK, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 707PKE28F707PKE28FHM623517D4T, 3TCEFVD67N, K70R, M184V, K219EV106M, V179D, F227FLK20R, V35T, E36A, T39E, V60VI, K101A, K103KR, K104R, K122E, D123N, I135IMT, E138S, T165I, K173M, Q174K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, K277R, Q278N, T286A, E291D, V292I, I293V, P313T, V317AC
 707PKE29F707PKE29FHM623518D4T, 3TCEFVD67DN, M184V, K219RV106M, V179D, F227LK20R, V35T, T39E, V60VI, K102N, K122KE, I135V, S162SN, E169KR, K173E, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, I326VC
 707PKE50F707PKE50FHM623532D4T, 3TCEFVD67DN, M184V, K219EQV106M, V179DP4S, K20KR, V35T, T39E, S48T, V60I, K122E, D123S, I135M, D177E, T200A, Q207E, R211K, V241VL, V245N, A272P, T286A, E291D, V292I, I293V, S322A, D324EC
van Zyl (2011)A117A117JN638075D4T, 3TCEFVD67DG, M184V, T215FV106M, V179D, M230LV35M, T39E, S48T, K102Q, K103KR, K122E, D123G, E138ED, S162C, K173A, T200A, Q207E, V245Q, E248DC
 A150A150JN638088D4T, 3TCEFV V179DV35T, T39E, K122KE, D123S, K173T, Q174K, I178M, T200A, Q207E, F214L, V245LC
 A223A223JN638132AZT, 3TCEFVM184VV179D, G190A, M230LV35T, T39E, S48T, K122E, D123S, E169G, D177E, T200A, Q207E, L228R, V245QC
 A268A268JN638160D4T, 3TCEFVM184VV106M, V179DV35T, T39D, S48T, K102KR, K104KR, K122E, D123DN, I135L, K173A, T200A, Q207E, R211K, F214FL, V245QC
 A272A272JN638164D4T, 3TCNVPM41L, K65R, V75I, M184VV106M, V179DK20R, V35T, T39E, S48T, S68G, K103R, K122E, D123N, I132L, S162C, K173A, Q174K, I178L, T200A, Q207E, R211RK, V245EC
 A277A277JN638168D4T, 3TCNVPL210WV106M, V179DT27S, V35T, E36A, T39D, S48T, K122E, D123S, S162C, F171Y, K173A, Q174K, D177E, T200A, Q207E, R211K, V245QC
 A284A284JN638175D4T, 3TCNVPM184VV179D, Y181CT27I, V35T, E36A, T39E, S48T, V90I, K103R, K122E, D123S, T139A, S162C, T200A, Q207E, R211K, F214L, V245QC
 A340A340JN638200D4T, 3TCEFVM184VV179D, Y188LV35T, T39E, S48T, K122E, D123N, I135T, K173A, Q174E, D177E, T200A, Q207E, K238R, V245QC
Brehm (2012)35ZA35ZA.84JN601969D4T, 3TCEFV V179DV35T, E36A, T39D, S48T, W88C, K122E, D123G, I135T, E138S, K173A, Q174K, D177E, T200A, Q207E, F214L, V245H, D250E, K277R, T286A, E291D, V292I, I293V, Q334NY, G335D, R356K, G359T, T369A, T377L, T386I, K390R, A400I, E404D, E413D, V435A, T470S, D471E, H483Q, L484I, L491S, V496I, S519N, Q524L, K530R, A534S, A554K, K558RC
 60ZA60ZA.60JN602022D4T, 3TCEFVK65R, M184VV106M, V179DV35T, E36A, T39E, S48T, K122E, D123N, I132L, I135T, S162C, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q, S251N, A272S, K275Q, K277R, R284K, T286A, E291D, V292I, I293V, P313Q, Q334H, R356K, G359T, T377M, K390R, A400T, T403S, E404D, V435A, L452T, R461K, V466I, T470N, D471E, T477A, H483Q, S519N, I526V, K527N, K530R, V531I, A554KC

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