<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation E138Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 24
Patients 76
Isolates 78
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Marconi (2008)SW093SW093EU308102AZT, 3TCEFVM184VK103N, Y188LS48T, V60I, K122P, I132IV, E138Q, Q145QE, K173A, Q174K, D177E, Q197P, T200A, Q207A, R211K, V245QC
Waleria-Aleixo (2008)08PR05026308PR050263FJ591292NRTINNRTIM41L, M184V, L210W, T215YK101P, K103SV35R, T39D, S48T, V60I, K122E, D123S, I135T, E138Q, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, V317A, G335DC
 08PR05034008PR050340FJ591368NRTINNRTIM184VG190AV35T, E36A, T39D, S48T, K101A, E138Q, E169A, K173A, V179I, T200A, Q207AE, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, G335DC
Deshpande (2009)Pat122212RTFJ530819NRTINNRTID67N, T69D, K70R, M184V, K219QK103NV35T, T39E, S48T, V60I, A62P, K102KR, K122E, D123S, I135T, E138Q, K173A, Q174R, D177E, T200A, E203K, Q207E, R211KC
Hosseinipour (2009)88218821GQ228379D4T, 3TCNVPD67N, M184V, T215YK103NT39E, A98S, V118VI, K122E, D123S, I135IT, E138Q, S162C, K173A, Q174K, N175NY, D177E, I178IM, G196M, T200A, Q207E, H208HY, R211RK, V245TC
Deshpande (2010)34IND43534IND435GU108161AZT, 3TCNVPM41L, D67N, T69D, K70R, L74I, M184V, T215F, K219WK103N, V108VI, Y181CV35T, E36A, T39D, V60I, D121Y, K122E, D123E, I135T, E138Q, S162A, K173A, D177EG, T200A, Q207E, R211K, L228H, V245KC
El-Khatib (2010)Pat05410ZA_SAVE2320HQ012332D4T, 3TCEFVM184VY188LV35T, E36A, T39E, S48T, V106L, V118I, K122E, D123N, E138Q, T165TI, K173IRT, Q174K, T200A, Q207E, R211K, F214L, V245Q, D250EC
Ngo-Giang-Huong (2011)PHPT3789PHPT3789RTHQ996467D4T, 3TCNVPM184VK101E, G190AK32R, V35T, T39K, S48T, A98S, K122E, E138Q, K166R, K173A, Q174R, D177E, I178M, G196M, T200A, E203K, Q207DN, R211KQ, F214LC
Sigaloff (2011)GP00022848GP00022848_1JN381557D4T, 3TCEFVM184VK103N, P225HV35T, T39E, S48T, V60I, K122E, D123S, I135L, E138Q, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293VC
  GP00022848_2JN381558D4T, 3TCEFVM184VK103N, P225HP14PT, M16MK, D17DY, G18GA, V35T, T39E, S48T, V60I, K122E, D123S, I135L, E138Q, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293VC
van Zyl (2011)A98A98JN638230AZT, 3TCEFVM184VV106MV35T, T39E, S48T, V60I, T69S, K122E, D123S, I135T, E138Q, K173A, T200A, I202V, E204K, Q207E, R211K, F214L, V245QC
Hoffmann (2013)5652456524KJ081300TDF, FTCEFVM184VK103N, V108VI, P225HV35T, E36A, T39E, E40D, S48T, V60VI, K122E, D123N, I135L, E138Q, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250EC
 418251418251KJ081321TDF, FTCNVPK65R, D67N, M184VG190AV35T, T39E, S48T, K102R, D121H, K122E, E138Q, S162C, K173T, D177E, I178L, T200A, Q207K, R211K, V245KC
Manasa (2013)RES331RES331KC951787D4T, 3TCNVPM184VV106AV35T, E36A, T39E, S48T, K49R, V60I, K122E, I135T, E138Q, K173A, Q174K, D177E, T200A, I202V, Q207A, R211K, H221Y, V245Q, A272P, T286A, E291D, V292I, I293VC
 RES122RES122KC951707D4T, 3TC, TDFNVP, EFVK65R, M184VL100I, K103N, K238TK20R, V35T, E36A, T39E, S48T, E53D, V60I, K122E, D123N, E138Q, K173A, Q174K, D177E, I178M, T200A, Q207E, V245E, A272P, E291D, V292I, I293VC
Van Zyl (2013)357010.ZA.GT1037KC422890D4T, 3TCEFVM184VK101E, K103N, G190AV35T, T39E, S48T, K49R, S68G, K82R, K122E, D123N, I135IT, E138Q, E169K, K173E, D177EG, T200A, Q207KN, R211RK, V245Q, D250EC
 534412.ZA.EC175KC423814D4T, 3TCEFVY115YF, M184VK103N, P225HK20R, V35T, E36A, T39E, S48E, D123S, E138Q, L149LP, K173T, Q197R, T200A, Q207K, R211K, V245Q, D250EC
 359609.ZA.GT913KC424398D4T, 3TCEFVM184VK103KN, V106M, V179VDK20R, V21VI, V35T, E36A, T39K, K43E, V60I, K122E, E138Q, T165I, K173A, Q174K, E194D, T200A, Q207E, R211K, F214L, V245QC
 442812.ZA.EC166KC423807D4T, 3TCEFVK70KE, M184VG190EV35T, E36A, T39E, S48T, S68SG, D121H, K122E, D123DE, I135V, E138Q, S162C, K173A, D177E, T200A, Q207G, R211K, H221Y, V245QC
 198010.ZA.GT1194KC423033D4T, 3TCEFVA62V, M184VK103N, V106ME6D, K20R, V35T, T39E, S48T, V60I, K122E, E138Q, T165I, K173T, D177E, T200A, I202V, Q207A, R211K, L228LR, D237DN, V245EC
 304010.ZA.GT1072KC422909AZT, 3TCEFVM184VK103N, V108IV35T, E36A, T39E, S48T, V60I, K122E, D123N, I135M, E138Q, K173T, D177E, I178L, T200A, Q207D, R211K, K219S, V245QC
  11.ZA.GT1505KC423290AZT, 3TCEFVM184VK103N, V108IK20R, V35T, E36A, T39E, S48T, E53X, V60I, K122E, D123N, I135M, E138Q, K173T, D177E, I178L, I180IV, T200A, Q207D, R211K, V245QC
Steegen (2014)12ZAKS21312ZAKS213KJ176493ABC, 3TC, D4TEFVL74V, M184VK103N, V106MV35T, T39E, S48T, V60I, K122E, D123S, E138Q, K173A, Q174K, T200A, Q207A, R211K, F214L, T240A, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, G335DC
 11ZAKS12711ZAKS127KJ176409D4T, 3TCEFVD67N, K70R, M184V, K219Q, N348IK103N, K238T, Y318FV35T, T39E, T69N, K122E, D123S, E138Q, S162C, K173A, Q174K, N175Y, I178L, E194D, G196V, T200A, K201KI, E203K, Q207E, L228H, E233ED, Q242QE, V245Q, P247A, E248D, D250E, A272P, E291D, V292I, I293V, K311R, D324E, Q334H, G335DC
 12ZAKS20512ZAKS205KJ176485D4T, 3TCEFVM184VK103N, P225HP4PT, K20R, V35T, T39E, S48T, V60I, V118I, K122E, D123G, I135L, E138Q, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, K277R, T286A, E291D, I293V, D324E, I329L, Q334H, G335DC
 12ZAKS36112ZAKS361KJ176640D4T, 3TCNVPA62AV, M184VK101KE, G190AI5IV, E6EK, V8I, M16MV, K20R, V35T, E36A, T39E, S48T, K122E, I135T, E138Q, S162SC, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, I329V, Q334H, G335D, R356K, G359T, E370Q, A371V, T377Q, I382IT, K390R, E396D, A400T, E404DC
 10ZAKS03410ZAKS034KJ176316D4T, 3TCEFVM184V, T215FK101KE, G190QK20R, V35T, E36A, T39E, S48T, K49KR, V60I, L109I, D121Y, K122E, E138Q, K173A, T200A, Q207E, V245Q, D250E, A272P, K275Q, K277R, Q278H, L283LI, T286A, E291D, V292I, I293VC
 11ZAKS13011ZAKS130KJ176412D4T, 3TCEFVD67N, K70KR, M184V, K219KQK103N, V106MK20R, V35T, E36A, T39E, S48T, K102KR, K122E, E138Q, K173A, D177G, T200A, Q207E, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, I293V, E308K, K311R, S322A, Q334H, G335DC
Wallis (2014)4115641156KM458565NRTINNRTIM184V, T215YK103NV35T, T39E, S48T, V60I, K122E, D123S, I132V, E138Q, K166KR, T200A, Q207E, R211KC
 4200042000KM458576NRTINNRTIM41L, M184V, T215FYA98G, K103NV35T, E36A, T39D, E44ED, S48T, E138Q, S162A, K173T, T200A, E203ED, Q207E, H208HY, R211KC
Saravanan (2015)CTLA10CTLA10KP993613NRTINNRTID67N, K70R, M184V, K219QK103N, V108IV35T, T39DE, V60I, D121H, K122E, I135T, E138Q, S162A, K173T, D177E, I178L, G196GE, T200A, Q207G, F214LC
 CTLA68CTLA68KP993671NRTINNRTID67N, M184V, T215FK103N, V108IV35T, T39E, S48T, V60I, V90VI, K101R, D121Y, K122E, I135T, E138Q, S162T, K173A, D177E, I178L, T200A, Q207E, H208Y, R211K, L228FC
 CTLA482CTLA482KP994085NRTINNRTIM41L, M184V, L210W, T215Y, K219NV108IK32E, V35T, E36A, T39E, E44D, V60I, I135R, E138Q, K173A, D177E, I178L, Q197K, T200A, E203K, Q207E, R211K, H221YC
 CTLA64CTLA64KP993667NRTINNRTID67G, T69D, K70R, M184V, K219QK101E, Y181C, G190AE28K, K32E, V35T, T39D, S48T, V60I, K122E, D123N, E138Q, K166R, D177E, I178M, Q197E, T200A, Q207K, F214LC
 CTLA300CTLA300KP993903NRTINNRTIM184V, T215FK103N, V108IV35T, T39E, E40F, V60I, D121Y, K122E, I135T, E138Q, S162C, T165L, K173A, T200A, Q207E, L228FC
 CTLA328CTLA328KP993931NRTINNRTID67N, T69D, K70R, M184V, T215F, K219QK101E, V106M, V108I, G190A, F227LV35T, T39E, V60I, I94L, D121HY, K122E, I135T, E138Q, K173AT, Q174QK, D177E, T200A, E203D, Q207A, R211K, F214L, H221HYC
 CTLA452CTLA452KP994055NRTINNRTIM41L, D67N, K70R, M184V, L210W, T215Y, K219EK103NK22R, V35T, T39D, V60I, W88C, I94L, D121Y, K122E, I135L, E138Q, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, L228RC
 CTLA207CTLA207KP993810NRTINNRTIM184V, T215YK103N, P225HT39N, S48T, V60I, K101Q, I135L, E138Q, I142T, S162A, K173A, Q174K, T200A, Q207A, R211KC
Seu (2015)ZM.HIVDRM.58ZM.HIVDRM.58KP995668AZT, 3TCNVPD67N, K70R, M184V, K219QK103NK20R, V35T, T39E, S48T, K49R, V60I, K122E, D123S, E138Q, E169K, K173A, D177E, G196E, Q197K, T200A, Q207N, R211K, V245Q, A272P, V292I, I293V, P294TC
Skhosana (2015)11ZALS05011ZALS050KM115782D4T, 3TCNVPM41L, D67N, M184V, L210W, T215YK103N, K238TV35T, T39E, E44D, V60I, V118I, K122E, D123S, E138Q, R172K, K173A, Q174K, N175Y, D177E, I178L, T200A, K201I, Q207E, R211K, V245Q, A272S, T286A, E291D, V292I, I293V, D324E, Q334D, G335DC
 12ZALS13712ZALS137KM115756TDF, 3TCEFVD67N, K70E, M184VV106M, V179DV35T, T39E, S48T, V60I, K122E, D123S, E138Q, K173A, Q174K, D177E, I178L, I195V, T200A, E203K, Q207E, R211K, P243ST, V245Q, A272P, K277R, E291D, V292I, I293V, Q334HN, G335D, K350KR, R356K, G359S, A376S, T377M, S379C, I382IT, K390R, A400T, E404D, E432DC
 12ZALS13612ZALS136KM115817TDF, 3TCNVPK70KE, M184VG190AP4S, E6K, V35T, E36EA, T39E, S48T, V60I, S68G, K101A, K122E, E138Q, A158AS, K173A, Q174K, D177E, T200A, Q207E, R211K, F214FL, V245Q, A272P, E291D, V292VI, I293V, Q334N, G335D, G359T, A371V, I375V, T377L, I382ILST, K390R, A400T, E404DC
 11ZALS07611ZALS076KM115781D4T, 3TCNVPM184VK103NK20KR, V35T, T39E, S48T, V60I, K122E, I135M, E138Q, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E, Q334D, G335DC
 11ZALS01011ZALS010KM115749D4T, 3TCNVPD67N, K70R, M184VK103N, P225HV35T, T39E, S48T, V60I, K64R, K122E, D123S, I135T, E138Q, I142V, K173A, Q174K, D177E, T200A, Q207D, R211K, V245QC
 11ZALS06811ZALS068KM115872D4T, 3TCNVPM41L, M184V, T215YK103NV35T, E36A, T39E, S48T, V90I, A98S, K122E, D123N, E138Q, S162Y, K173L, Q174K, D177G, T200A, Q207E, R211K, V245Q, A272P, I274IV, K275R, Q278N, T286A, E291D, V292I, I293IV, E308X, I309VC
 11ZALS07211ZALS072KM115814D4T, 3TCNVPM184VK103NE6D, T27S, E28EK, V35T, T39E, S48T, K101Q, K122E, I135T, E138Q, S162C, K173A, Q174K, D177E, I178L, T200A, I202V, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334EC
 11ZALS06411ZALS064KM115776D4T, 3TCNVPD67N, K70R, M184V, T215TFIS, K219QK103N, Y181YCK20KR, K22KR, V35T, T39A, K46KQ, S48T, V60I, K64R, W88C, K122E, D123S, I135M, E138Q, K166R, K173A, Q174R, D177E, I178L, I195L, G196GE, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, A288T, E291D, V292I, I293VC
Boillot (2016)MBI03MBI03KT315975AZT, 3TCEFVM184VG190AV35T, E36A, T39E, V90I, K122E, D123N, E138Q, A158S, T165I, K173T, D177E, T200A, Q207E, R211K, V245M, E248D, D250EC
Dinesha (2016)T60T60KX275104TDF, 3TCEFVM41L, D67N, V75M, M184V, T215YL100I, K103NV35T, T39D, V60I, D121DY, K122E, E138Q, K173A, D177E, I178IM, G196E, Q197S, T200A, H208Y, L210S, R211K, W212M, H221Y, L228QC
 T19T19KX275063TDF, 3TCEFVM184VK103S, V106MV35T, T39D, S48T, V60I, D121Y, K122E, E138Q, S162A, K173A, D177E, T200A, Q207G, R211KC
 T17T17KX275061TDF, 3TCNVPM184VK103N, P225HV35T, E36A, T39D, V60I, V90VI, D121Y, K122E, S134C, E138Q, K173A, Q174R, D177E, T200A, Q207E, R211KC
Lam (2016)1601100116011001KR868083AZT, 3TCNVPM41L, D67N, V75VM, M184V, L210W, T215YA98G, K103NK20KR, V35T, T39D, E44D, V60I, D121H, K122E, I135L, E138Q, I142V, S162A, K173T, Q174K, N175NY, D177E, I178IM, G196GE, T200A, E203D, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, L310I, G335DC
 2002202420022024KR868079D4T, 3TCNVPM184VK103NV35M, E36A, T39E, K43R, S48T, K122E, D123N, I135T, E138Q, S162C, K173T, Q174K, N175NY, T200E, Q207E, R211K, F214L, V245Q, A272P, Q278H, K281R, E291D, V292I, I293V, Q334N, G335DC
 2002201220022012KR867857AZT, 3TCNVPM41L, D67DN, M184V, T215YA98G, K103N, Y318YFK20R, V35T, T39E, S48T, V60I, K122E, D123G, E138Q, K173A, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, K275Q, L283I, R284K, T286A, E291D, V292I, I293V, Q334HC
Ndahimana Jd Riedel (2016)21112111KT982511NRTINNRTI  T39LS, E40ED, S48T, K103R, V118I, K122E, D123N, E138Q, K173A, D177G, V179S, T200A, Q207E, R211K, F214L, V245QC
Neogi (2016)549913.ZA.EC623KT592799TDF, 3TC, AZT, DDIEFVM41L, D67N, V75M, F77FL, T215FK103N, P225H, K238TV35T, T39E, S48T, V60I, K122E, D123N, E138Q, S162C, K173A, Q174KR, D177E, I178M, T200A, Q207D, R211K, V245EC
Steegen (2016)GFMPB097GFMPB097KU128331TDF, 3TCEFVD67DGNS, K70E, M184V, K219KRK103N, V108IK20R, K22KR, V35T, E36A, T39E, S48T, V60I, K122E, D123DGNS, E138Q, I142T, K173A, Q174K, D177E, I178L, T200A, Q207A, R211K, F214L, L228H, V245Q, A272P, K275Q, T286A, A288AV, E291D, V292I, E312Q, I329L, Q334N, G335D, R356K, M357R, G359T, T369V, E370D, A371AV, A376S, T377V, K390R, A400T, E404DC
 GFNWB032GFNWB032KU128268TDF, FTCEFVK65R, M184VL100I, K103NK20KR, V35T, E36A, T39E, S48T, K122E, D123S, E138Q, S162C, K173AST, D177E, V179VI, T200A, I202IV, Q207E, R211K, V245Q, A272P, I274IV, K275KQ, Q278N, E291D, V292VI, P313T, Q334N, G335D, R356K, M357R, G359T, T377L, K390R, A400T, E404D, V435MC
 GFFSB078GFFSB078KU127785D4T, 3TCEFVM184VK103S, V106M, Y188FK20R, V35T, T39E, S48T, V60I, K122E, I135M, E138Q, K173A, T200A, Q207G, R211KC
 GFKZB415GFKZB415KU128358TDF, FTCEFVK65R, M184VL100I, K103N, Y318FM16L, V35T, T39E, S48T, S68SG, V118I, K122E, D123S, I135T, E138Q, K173A, Q174K, D177G, Q197K, T200A, Q207N, R211K, F214L, V245Q, E248T, I257L, A272P, E291D, I293V, Q334H, G335EC
 GFFSB028GFFSB028KU127667TDF, 3TCEFVK65KR, K70KE, M184VK101E, G190CV35T, T39E, S68SN, W88C, K122E, D123N, I135T, E138Q, I142T, S162SN, K173V, Q174K, D177E, I178M, T200A, Q207N, L210LS, R211KC
 GFWCB003GFWCB003KU127592D4T, 3TC, AZTEFVK70R, M184VK101P, K103N, K238TV35T, T39E, S48T, T69N, E138Q, K173A, Q174R, D177E, I178L, V179I, T200A, R206T, Q207T, F214L, L228R, V245QC
 GFECB024GFECB024KU127722D4T, 3TCNVPM184VK103NT27S, V35T, E36A, T39D, S48T, V60I, V90VI, K102HQ, D123N, I135T, E138Q, S162A, K173A, Q174K, D177E, I178IL, T200A, Q207E, V245K, K277KR, T286A, E291D, V292I, I293V, G335D, R356K, M357R, G359T, T377L, K390R, E399D, A400T, E404DC
 GFKZB099GFKZB099KU127974D4T, 3TC, TDF, FTCNVP, EFVM41L, L74LI, M184V, T215YA98G, K103N, V108VI, Y318FV35IMT, E36EQ, T39DE, S48T, V60I, V118VI, K122E, D123S, E138Q, K173A, Q174QK, N175NY, D177E, T200AE, Q207E, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334D, G335D, R356K, M357R, G359AT, T369V, T377M, K388KR, K390R, A400T, E404DC
 GFNWB023GFNWB023KU128043D4T, 3TCEFVM184VK103S, V106MV35T, T39E, S48T, V60I, K104R, K122E, D123S, I135M, E138Q, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q, A272P, I274V, K275R, T286A, E291D, V292I, I293V, H315Y, Q334N, G335D, R356K, M357T, G359T, K366R, T377L, K390R, A400T, E404D, V435AC
 GFKZB219GFKZB219KU128138AZT, 3TCEFVM184V, N348IK103NV35T, E36A, T39E, S48T, V60I, K122E, I135L, E138Q, T165I, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, A272P, E291D, V292I, I293V, Q334D, G335S, R356K, G359T, T369V, I375V, T377LC
Kityo (2017)8306683066KY061624NRTINNRTIM41L, D67DN, M184V, T215YG190AS48T, V60I, K102Q, K122E, D123G, I135M, E138Q, K173A, Q174K, D177E, I178M, T200A, Q207D, R211KC
 6604766047KY061414NRTINNRTID67N, F116Y, Q151M, M184V, K219QV106M, G190GA, F227LS48T, L109LI, K122E, E138Q, T165I, K173T, Q174K, T200A, I202V, Q207N, R211K, F214LC
 8336183361KY061916NRTINNRTIM41L, A62V, V75T, M184V, L210LW, T215FK103NS48T, V118I, K122E, D123N, E138Q, I142V, K173A, I178ILM, T200A, Q207E, R211K, D218EC
 8311283112KY061669NRTINNRTIM41L, D67N, M184V, T215YK103N, G190GA, K238DNE44D, K101Q, V111I, V118I, K122E, E138Q, T165TI, K173T, Q174KR, D177E, I178M, T200A, E203K, Q207D, L210S, R211K, K223QC
 8325183251KY061806NRTINNRTID67N, T69D, K70R, M184V, T215F, K219WK103N, K238TE53D, V118I, K122E, E138Q, K173A, Q174K, N175Y, D177E, I178M, T200A, K201KR, Q207E, H208Y, R211K, L228LHC
 6603166031KY061402NRTINNRTIK65KR, L74LV, M184VL100I, K103NS48T, V60I, K122E, D123S, I135M, E138Q, K166R, K173A, D177E, I178M, T200A, R206RK, Q207E, R211KC
 8339383393KY061947NRTINNRTID67N, K70R, M184V, K219QK103NS48T, V60I, K104KR, K122E, D123S, E138Q, K173A, Q174K, I178L, T200TA, E203EK, Q207E, R211K, F214LC
 8337783377KY061932NRTINNRTIM41L, D67DN, T69DN, V75VI, M184V, T215YA98AG, K103NK43KE, E44EAD, V60VI, V118VI, K122E, D123KNRS, I135IM, E138Q, S162A, K173AT, Q174K, N175Y, D177DE, T200A, K201I, Q207E, H208HY, L210LS, R211K, W212MR, D218DE, L228QC
 8312983129KY061686NRTINNRTIA62V, V75T, M184VK103NS48T, K122E, I135T, E138Q, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, F214LC
 8324183241KY061796NRTINNRTIM41L, L74I, M184V, L210W, T215YK103NS48T, V60I, R83K, K122E, D123N, I135M, E138Q, K173T, T200A, Q207K, R211KC
 8307183071KY061629NRTINNRTIM41ML, M184V, T215YK103NS48T, E53D, K102R, D121H, K122E, I135IM, E138Q, S162D, K173A, Q174K, D177E, I178L, G196K, T200A, Q207D, R211KC
 8336083360KY061915NRTINNRTID67N, K70R, M184V, K219QK103NE53D, V60VI, K101Q, K122E, D123S, I135MT, E138Q, K173A, Q174K, D177E, I178L, T200A, Q207E, R211KC