<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 31
Patients 109
Isolates 121
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2001)SE73SE73AF388136NoneNVP K103KNV35T, E36A, T39E, E40D, K43R, S48E, E53D, K101Q, K122E, D123G, E138A, S162Y, K173A, D177G, V179I, G196E, T200A, Q207D, V245Q, T253TP, A272P, K277R, T286A, E291D, V292I, K311RC
Johnston (2003)TC-62TC-62 D4T, DDI, AZT, 3TCNVP, EFVM184VG190AP4S, V21I, V35T, E36A, T39E, S48T, W88C, K101R, K122E, E138A, K173I, Q174K, D177G, T200A, Q207E, R211K, F214P, V245Q, E248DC
Shafer (2003)A384_06010601bEF548284D4T, DDIEFV  V35T, E36A, T39E, S48T, K102Q, K122E, E138A, S162C, E169EA, K173A, P176Q, T200A, Q207E, V245L, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
Eshleman (2004)SE73SE73_7dAY428676NoneNVP K103KN, V106VAV35T, E36A, T39E, E40D, K43R, S48E, E53D, K101Q, K122E, D123DG, E138A, S162Y, K173AT, D177G, V179I, G196E, T200A, Q207DN, V245Q, A272P, K277R, T286A, E291D, V292I, K311R, Q334EC
Eshleman (2004)ESH_Pat133ESH513AY435285NoneNVP  T7TI, V35T, E36A, T39E, E40D, S48T, D121DN, K122E, D123S, E138A, K173A, D177N, T200A, Q207E, V245E, A272P, K277KR, T286A, E291D, V292I, I293V, V317GC
Eshleman (2005)ESH5031ESH5031AY756849NoneNVP V106VMV35T, E36EA, T39E, S48T, E53D, K103X, K122E, D123S, E138A, K173IT, Q174QK, T200A, Q207D, R211K, V245L, A272P, K277R, T286A, E291D, V292I, I293V, P294PQ, P313TC
 ESH11065ESH11065AY756885NoneNVP  V35T, E36EA, T39E, S48T, K102Q, K122E, D123G, E138A, S162SC, K173A, G196K, T200A, Q207E, P243PT, V245Q, E248D, A272P, K277KT, K281R, T286TA, E291D, V292I, I293VC
 ESH9009ESH9009AY756875NoneNVP  V35T, E36EA, T39E, S48T, K102Q, K122E, D123G, E138A, S162C, K173A, G196K, T200A, Q207E, V245Q, E248D, A272P, K277KT, K281R, T286TA, E291D, V292I, I293V, S322SAC
Lee EJ (2005)Zim17_8wZim17_8wAY901238NoneNVP  T39E, S48T, V118I, K122E, D123N, E138A, T139A, R172K, K173S, Q174K, T200A, Q207E, F214L, V245Q, E248DC
 Zim31_8wZim31_8wAY901246NoneNVP  T39E, S48T, E53ED, K122E, D123N, E138A, I142T, K173IM, Q174K, I178L, T200A, I202V, Q207E, R211K, F214FL, P243T, V245Q, E248DC
Non-B Workgroup (2005)UK4914UK4914AY901811AZT, 3TCNVPM184VA98AG, K103NV35T, E36A, T39E, S48T, K122E, D123S, I135L, E138A, K173A, I178L, T200A, Q207D, R211K, E224EKC
 UK4795UK4795AY901817AZT, 3TCNVPM184VK103NV35T, T39E, E40D, S48T, V118VI, K122E, D123G, I135IT, E138A, K173A, T200A, Q207E, R211K, F214LC
 UK4799ASRU4799AY901821AZT, 3TCEFV, NVPM184VK101KE, G190AV35T, T39E, S48T, K122E, D123S, I135IL, E138A, K173T, Q174K, T200A, I202V, Q207E, F214L, P225PLC
 UK4700UK4700AY9018253TC, DDIEFVM184VK101KE, V106M, G190SV35T, T39E, V60VI, W88C, K122E, D123N, I135T, E138A, K173AT, Q174QK, T200A, E204EK, Q207QK, R211K, F214L, H221HYC
 TK2024TK2024 D4T, 3TC, AZT, DDIEFVM41L, M184V V35T, E36D, T39E, W88C, K122E, D123S, E138A, K173T, D177E, I178L, T200A, Q207K, H208Y, R211K, V245Q, L246X, A272P, K275R, V292I, I293V, V317A, D320DEC
  TK2024a D4T, 3TC, AZT, DDIEFVM184VV106MV35T, E36A, T39E, W88C, K122E, D123S, E138A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, S268C, A272P, K275R, Q278X, E291D, V292I, I293VC
  TK2024b D4T, 3TC, AZT, DDIEFVM184VK101E, V106M, G190AV35T, E36A, T39E, W88C, K122E, D123S, E138A, K173T, Q174K, D177E, T200P, Q207N, L209LV, R211K, F214L, V245Q, S268C, A272P, K275R, E291D, V292I, I293V, V317AC
 TK3035TK3035 AZT, 3TC, D4T, DDI, ABCNVP, EFVM41L, D67N, K70R, L74I, L210W, T215Y, K219EK101E, G190A, K238TV35T, E36A, T39E, V60I, K122E, D123S, I135T, E138A, R172RK, K173T, Q174K, T200A, E203K, Q207E, R211K, D218DE, V245Q, E248D, A272P, K275R, Q278H, E291D, V292I, I293V, G316E, V317VG, Y319XC
 PL4804587649 3TC, DDIEFVM184VK103N, V106MV35T, T39D, S48T, V60I, W88S, D121H, K122E, I135X, E138A, T139A, K173A, Q174K, I178L, V179I, T200A, Q207E, R211K, F214FL, V245Q, E248D, A272P, K275R, Q278H, K281KR, L283I, T286A, E291D, V292I, I293V, V317VA, I329VC
Weber (2005)F64950F64950AY677514AZT, 3TCNVPM184VK103KN, G190GAV35T, E36A, T39E, S48T, E53D, K101X, K122E, D123S, I135LP, E138A, K173T, Q174K, T200A, E203A, Q207E, R211K, F214L, V245Q, E248N, D250E, A272P, K275R, Q278H, E291D, V292I, I293V, V317A, I329VC
 M46228M46228AY677563D4T, DDI, AZT, 3TCNVP  K32R, V35AE, E36A, T39E, S48T, K122E, D123N, I135T, E138A, K173I, G196K, T200A, Q207E, R211K, V245Q, E248D, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, V317A, D324EC
 M93982M93982AY677571D4T, DDINVPM184MV, T215TS I31IL, V35T, T39E, K64KR, K122E, D123DN, I135T, E138A, I142IV, K173T, Q174K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, K275R, Q278H, E291D, V292I, I293V, K311KR, V317A, D324DE, I329VC
Baxter (2006)48-22542254-30930DQ877888NRTINNRTID67N, K70R, M184V, T215F, K219WA98G, K101E, V108I, Y181CV8VI, K20R, E28K, K32E, V35K, T39E, V118I, K122E, D123S, I135T, E138A, K173A, D177G, V179I, T200A, E203K, L205F, Q207D, H208Y, L210S, R211K, D218E, K223Q, L228H, Q242K, V245Q, K275Q, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, G359T, T377L, K385R, K390RC
Doualla-Bell (2006)Pt23FDB_Pt23EF434886AZT, 3TC, D4T, DDINVPM41L, D67N, T69D, V75T, T215YV108I, V179D, Y181CK20R, V35T, T39D, E44D, D121C, K122E, I135T, E138A, K173T, D177E, I178L, V189I, T200A, E203D, E204K, Q207D, R211K, H221Y, P243S, V245Q, A272P, E291D, V292I, I293VC
 Pt20FDB_Pt20EF434889AZT, 3TC, D4T, DDI, ABCNVP K103NV35T, T39E, K122E, D123S, E138A, T139A, K173T, Q174K, T200E, Q207E, R211K, F214L, D250E, S251D, A272P, Q278H, T286A, A288T, V292I, I293VC
 Pt6FDB_Pt6EF434898AZT, 3TC, D4T, DDIEFVK65R, K70R, V75I, F116Y, Q151LMK103N, V106VAP1PA, L26LS, V35Q, T39D, S48T, V60I, S68SG, T69TI, K122E, I135T, E138A, I142T, K173A, Q174K, D177E, I178LV, G196E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, E291D, V292I, I293V, V317AC
Martinson (2007)KEH169MKEH169MEU152442NoneNVP  P4S, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123S, E138A, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E308K, K311RC
 CHB253BCHB253BEU152461NoneNVP  E6N, V35T, T39E, S48T, K104R, K122E, E138A, K173I, Q174K, I202V, Q207A, R211K, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, N306K, V314AC
 CHB253MCHB253MEU152462NoneNVP  E6KN, V35T, T39E, S48T, K104R, K122E, E138A, K173IMT, Q174K, T200TA, I202V, Q207A, R211KT, F214L, V245Q, E248DN, A272P, K277R, T286A, E291D, V292I, I293VC
Novitsky (2007)16461646_3858EF026222AZT, DDINNRTI V179DP4S, V35T, E36A, T39E, S48ST, K103KR, K122E, D123S, E138A, K173A, Q174K, T200A, I202V, Q207E, R211K, F214L, L228LH, V245E, A272P, K277R, A288T, E291D, V292I, I293V, H315FC
Seoighe (2007)CHB14406_C144EF381785NoneNVP  P4PS, K11KE, I31IM, V35AT, E36A, T39E, S48T, K122E, D123G, I135V, E138A, S162C, K173AT, T200E, Q207A, R211K, V245Q, A272P, K275Q, Q278K, T286A, E291D, V292I, I293VC
 CHB16806_C168EF381793NoneNVP K103KN, G190GAV35I, I135V, E138A, T165TI, G196GE, P243A, V245K, K277KR, I293IVC
 CHB19106_C191EF381817NoneNVP K103KN, V106VMK20R, V35T, E36A, T39E, S48T, K122E, E138A, E169Q, K173T, Q174K, D177N, T200A, I202V, Q207E, R211K, F214L, P243T, V245Q, A272P, K275R, Q278H, K281R, T286TA, E291D, V292I, I293VC
 CHB25306_C253EF381841NoneNVP V106VME6KN, V35T, E36EA, T39E, S48T, K104R, K122E, E138A, K173IT, Q174K, T200A, I202V, Q207A, R211KT, F214L, V245Q, E248DN, A272P, K277KR, T286A, E291D, V292I, I293VC
 CHB27006_C270EF381855NoneNVP K103KNK20R, V35T, T39E, S48T, V60I, W88C, K122E, D123G, I135V, E138A, K173D, Q174K, D177G, T200TA, Q207E, R211K, F214L, V245E, A272P, K277R, T286A, E291D, V292I, I293VC
 CHB32106_C321EF381885NoneNVP K103KN, V106VMV35T, T39E, S48T, K122E, D123DGNS, E138A, S162C, K173A, Q174E, T200A, Q207E, V245Q, A272P, K275Q, V276T, K281R, T286V, E291D, V292I, I293VC
 CHB3306_C33EF381891NoneNVP K103KN, V106VMV21I, V35T, E36A, T39E, S48T, V60VI, K122E, D123G, E138A, A158S, S163ST, T165I, K173A, Q174K, D177EG, T200A, Q207E, R211RK, Q242QH, V245Q, A272P, K277KR, T286A, E291D, V292I, I293VC
 CHB35306_C353EF381905NoneNVP K103KN, V106VA, V179DV35T, E36A, T39E, E40D, S48T, K104R, V118I, K122E, D123S, E138A, T139A, T165I, K173T, Q174K, T200A, I202V, Q207G, R211K, F214L, V245Q, E248D, A272P, T286TA, E291D, V292I, I293V, L295LVC
 KEH16906_K169EF381996NoneNVP K103KN, V106VMP4S, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123S, E138A, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 KEH3106_K31EF382010NoneNVP K103KNV35T, E36A, T39E, E40D, S48T, V60I, K102L, V118I, K122E, D123S, E138A, T139A, I142V, K166R, K173A, Q174N, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, T286A, K287KR, E291D, V292I, I293VC
 PL10406_PL104V2EF382052NoneNVP Y181YCV35T, T39E, S48T, K102R, D121DE, K122E, E138A, K173A, Q174K, T200A, Q207D, R211K, V245K, A272P, K277R, T286A, E291D, I293VC
 PL19306_PL193V2EF382118NoneNVP  V35T, T39E, S48T, K104R, K122E, D123N, E138A, T165TI, K173T, Q174K, I178IL, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
 PL6206_PL62V2EF382198NoneNVP  V8VI, K20R, V35T, E36A, T39E, S48T, K122E, D123S, N136T, E138A, T165I, F171S, R172G, K173T, Q174K, T200A, E203D, Q207E, R211RK, F214L, V245Q, K249R, D250DE, A272P, K275R, Q278H, E291D, V292I, I293VC
 PL7006_PL70ENEF382205NoneNVP A98GP4S, V35T, T39E, S48T, K122E, E138A, K173T, Q174K, T200A, Q207E, F214L, V245H, A272P, K275R, Q278H, K281KR, T286A, E291D, V292I, I293VC
  06_PL70V2EF382206NoneNVP A98G, K101KE, K103KNP4S, V35T, T39E, S48T, K122E, E138A, K173T, Q174K, T200A, Q207E, F214L, V245H, A272P, K275R, Q278H, K281KR, T286A, E291D, V292I, I293VC
 PL25306_PL253V2EF382304NoneNVP  V35T, E36A, T39D, S48T, K122E, D123G, E138A, K166KR, K173A, T200AV, Q207A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 PL26706_PL267V2EF382306NoneNVP  P4S, V35T, E36A, T39E, S48T, V60I, D121Y, K122E, E138A, T165I, K173I, Q174K, D177E, T200A, I202V, E203EG, E204Q, Q207E, R211K, F214L, V245N, D250E, A272P, T286A, E291D, V292I, I293VC
 PL32906_PL329V2EF382333NoneNVPM41LK103KNK20R, V35T, T39E, S48T, V60VI, K102Q, K122E, D123G, E138A, T139A, A158S, S162A, K173A, Q174K, V179I, T200A, Q207D, R211RK, V245KQ, A272P, E291D, V292I, I293VC
 PL35506_PL355V2EF382280NoneNVP  V35T, T39E, S48T, K104R, V118VI, K122E, D123G, E138A, K173T, Q174KR, D177E, I178IV, V179VI, T200A, Q207A, R211K, F214L, V245Q, E248N, A272P, E291D, V292I, I293VC
Marconi (2008)SW011sw011EU308029AZT, 3TCNVPD67N, K70R, M184V, T215F, K219QK103N, Y181IS48T, K49R, V60I, K102Q, K122E, D123S, I135L, E138A, E169D, K173A, Q174K, D177E, G196E, T200A, Q207E, F214L, V245QC
 SW039sw039EU308052AZT, 3TC, DDIEFV V106M, V179D, K238TE40D, S48T, V60I, D121H, K122E, E138A, I142ST, K173A, Q174K, D177E, T200A, Q207E, F214L, V245QC
 SW042SW042EU308055D4T, DDI, AZT, 3TCEFVM184VV106M, V179VEE40R, S48T, S68G, K101Q, K102R, K104R, K122E, D123S, E138A, K173I, Q174QK, D177DE, T200A, Q207E, R211K, F214L, V245QC
 SW092SW092EU308101D4T, 3TCEFVV75T, M184VA98G, K103N, P225HS48T, V60I, K122E, D123S, I135L, E138A, K173A, D177E, T200A, R211K, Q242QHR, V245QC
Nyombi (2008)TMS214TMS214EU251849NoneNVP  P4S, V35T, E36A, T39E, S48T, K122E, D123S, E138A, S162C, T200A, Q207E, R211K, V245C, A272P, K281R, L283I, E291D, V292I, I293V, P294T, L295MC
Pillay (2008)DR50DR50AY589903D4T, DDI, AZT, 3TCEFVM184VK103N, V106MP4S, E6K, V35T, E36A, T39E, S48T, V90VI, V118I, K122E, I135IL, E138A, T165I, K173I, Q174K, D177DE, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293VC
 DR67DR67AY589916AZT, 3TCNVP  T27TS, V35T, T39E, S48T, K122E, D123N, E138A, T165I, F171Y, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, D250DE, A272P, K277KR, Q278H, T286A, E291D, V292I, I293V, I329VC
Deshpande (2009)Pat23930artFJ530702AZT, 3TCNVPM41L, D67DN, K70KR, M184V, T215YK103N, K238TV21VG, L34LF, V35T, T39E, S48T, V60VI, K122E, D123S, I135L, E138A, S162C, K173A, T200A, Q207E, R211RK, V245QC
 Pat2205RTFJ530721D4T, 3TCNVP A98AG, K103NK20R, T27TS, V35T, T39E, S48T, V60VI, K122E, I135L, E138A, S162C, R172K, K173A, Q174R, D177E, I178L, T200A, L205LS, Q207E, R211K, V245QC
 Pat150164RTFJ530791NRTINNRTIM41L, D67N, L74LV, V75M, M184V, L210W, T215Y, K219KRK101E, K103KN, V106A, G190GA, F227LK20R, V35T, T39D, E44A, S48T, V60I, K82KR, A98AS, K122E, I135L, E138A, I142IV, K166R, K173A, I178L, V179I, T200A, Q207D, H208Y, R211KC
 Pat139186RTFJ530802NRTINNRTIM184V, T215NK103NV35T, T39N, S48T, K49R, V60I, K102Q, K122E, I135L, E138A, K166R, K173V, D177E, Q197K, T200A, I202V, Q207E, R211K, K219KTC
Hoffmann (2009)pat009MD78138 AZT, 3TCEFV  I31IR, V35T, E36A, T39E, S48T, K49R, K104R, F116FV, K122E, D123N, I135IT, E138A, Y146Y*, I159IT, T165I, K173T, Q174K, I178L, T200E, Q207A, R211K, F214L, V245Q, E248N, A272PSC
  MD116066 AZT, 3TCEFV  V35T, E36A, T39E, S48T, K49R, K104R, K122E, D123N, E138A, T165I, K173T, Q174K, I178L, T200E, Q207A, R211K, F214L, V245Q, E248N, A272PC
  MD025111 AZT, 3TCEFV  V35T, E36A, T39E, S48T, K49R, K104R, K122E, D123N, E138A, T165I, K173T, Q174K, I178L, T200E, Q207A, R211K, F214L, V245Q, E248N, A272PC
  MD052758 AZT, 3TCEFV V106VMV35T, E36A, T39E, S48T, K49R, K104R, K122E, D123N, E138A, T165I, K173T, Q174K, I178L, T200E, Q207A, F214L, V245Q, E248N, A272PC
Hosseinipour (2009)72417241GQ228299D4T, 3TCNVPM41L, D67DN, T69D, L74LV, M184V, L210W, T215Y, K219RK103N, K238TT39E, E44ED, V60I, V118I, K122E, D123N, I135LM, E138A, E169EA, F171Y, K173A, I195IT, T200A, I202V, Q207D, R211K, L228H, P243T, V245QC
 84558455GQ228306D4T, 3TCNVPM184VK101KE, Y188LC38C*, T39K, E40EK, K43E, S48T, D123E, E138A, Q197P, T200E, Q207KN, R211K, V245QC
 85668566GQ228311D4T, 3TCNVP  T39E, S48T, A98S, K122E, D123N, I135T, E138A, I142IV, K173A, D177G, T200A, Q207D, R211K, V245QC
 93219321GQ228349D4T, 3TCNVP  T39E, W88C, K122E, D123G, E138A, Q145C, K173A, Q174QK, T200A, Q207D, R211K, V245QC
 93639363GQ228357D4T, 3TCNVPM41L, D67N, L74I, V75S, M184V, L210W, T215Y, K219NV108VI, Y181IT39E, E44D, S48T, V118I, K122E, E138A, A158S, S162A, K166R, K173A, V179I, T200A, Q207A, R211K, D218E, V245QC
 85038503GQ228377D4T, 3TCNVPK65R, T69~, K219RK101E, Y181C, G190AT39E, S48T, V60I, S68G, K122E, D123S, E138A, P157A, K173A, D177E, T200A, I202V, E204K, Q207A, L210S, R211K, F214L, H221Y, V245QC
 82118211GQ228384D4T, 3TCNVPK70KEGR, F116FY, Q151QKLM, M184MVG190GET39E, S48T, K122E, D123NS, E138A, I142V, K166KR, K173I, Q174K, T200A, Q207A, R211K, F214FL, V245QC
Jones (2009)198227198227FJ659846NRTINNRTIM41L, D67N, L210W, T215Y K20R, V35T, T39E, V118VI, I135T, E138A, I142T, Q151QR, G152GE, P170PL, R172K, K173I, Q174K, D177E, T200A, E203K, Q207A, H208HY, R211K, K223KE, V245Q, E248ED, A272P, K277R, Q278H, E291D, V292I, I293V, S322A, G333E, Q334C, R356K, G359T, V365VI, S379AC
Kassaye (2009)TCDD-28TC28_2003FJ445707AZT, 3TC, D4TNVPD67N, K70R, M184V, T215V, K219QY181CV35T, T39E, S48T, V60I, T69N, K122E, D123G, I135T, E138A, I142V, I167IV, K173A, N175Y, G190X, T200A, I202V, Q207A, V245Q, D250EC
  TC28_2004FJ445727AZT, 3TC, D4T, TDFNVPD67N, K70R, T215F, K219QK101E, Y181C, G190AV35T, T39E, S48T, V60I, T69N, K122E, D123G, I135T, E138A, I167V, K173A, Q174K, N175Y, T200A, I202V, Q207A, H221YC
 TC-54TC54_2003FJ445731AZT, 3TC, D4TNVP  V35T, E36A, T39E, E40D, S48T, K49KQ, E53D, K102R, V118I, K122E, D123NS, E138A, T139A, E169EQ, K173T, Q174K, G196E, T200A, Q207E, F214L, V245Q, E248DC
Rajesh (2009)F6TRCFRT6FJ5953543TC, DDINVPM184MIVV106VM, Y181YC, F227FLL12I, K20KR, V35T, T39E, S48T, K49R, V60I, V90VI, D121Y, K122E, I135MR, E138A, S162C, T165TI, K173T, D177E, T200A, Q207E, V245Q, E248DNC
Wallis (2009)GT00328364GT00328364 AZT, 3TCEFVM184VK103NT7TA, V35T, T39K, V90VI, K122E, D123N, I132L, I135T, E138A, T139A, S162C, K173A, Q174K, D177E, I178M, T200A, Q207E, F214L, P243S, V245Q, R284K, T286AC
 22803932280393 AZT, 3TCEFVM184VV106M, V179EK20R, V35T, T39E, S48T, K49R, V60I, E138A, T139I, K173T, Q174K, T200A, I202IV, Q207E, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, P321T, D324E, I326IMC
 TJC2382730TJC2382730 D4T, 3TCNVPM184VK103NV35T, E36A, T39E, S48T, V60I, V118I, K122S, I135T, E138A, K173T, Q174K, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250DG, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, E297A, K311R, I329VC
 TJC2455335TJC2455335 D4T, 3TCEFVK65R, V75A, F77L, F116Y, Q151MG190E, P225HK20R, V35T, T39E, S48T, S68G, T69TI, K73M, W88S, K101R, K122E, E138A, P157A, R172K, K173A, V179G, T200A, Q207E, F214L, V245Q, A272P, T286A, V292I, I293VC
 TJC2394973TJC2394973 D4T, 3TCEFVM184VV106M, V179D, M230LE6K, K11N, K32R, V35T, T39E, S48T, W88S, K103R, K122E, D123N, E138A, K173T, Q174K, T200A, I202V, E204Q, Q207E, R211K, F214L, V245Q, E248D, D250A, A272P, K275R, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, I329L, Q334EC
 23464402346440 D4T, 3TCNVPK65R, V75I, F116Y, Q151M, M184VK101E, G190A, F227LV35T, T39E, S48T, V60I, S68G, V118I, K122E, D123S, I132L, E138A, T139A, K173T, Q174K, D177E, V179I, T200A, I202V, E204D, Q207E, R211K, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, V317A, I329LC
 TJC2443711TJC2443711 D4T, 3TCEFVM184VK101P, K103NK20R, V35T, T39E, S48T, V60I, K122E, D123G, I135IT, E138A, T139A, K166R, K173T, Q174R, I202V, R211K, F214L, V245Q, D250DE, A272P, K277R, T286A, V292I, I293V, E297EK, Q334EC
 GP60765845GP60765845 AZT, 3TCEFV  V35T, E36A, T39E, S48T, K122E, D123S, E138A, A158S, K166KR, K173T, D177E, T200A, R211K, D250E, A272P, K277R, E291D, I293VC
 GT00464533GT00464533 D4T, 3TCEFV  P4S, V35T, E36A, T39E, S48T, V60I, K122E, D123S, E138A, A158S, K173A, Q174K, T200A, Q207D, R211K, V245Q, A272P, K277R, E291D, V292I, I293VC
 23604342360434 D4T, 3TCEFVM184VK101KE, K103KNV21VI, V35T, E36A, T39D, W88S, V118I, K122E, D123N, I135V, E138A, I142IT, E169Q, K173T, Q174K, T200A, K201KR, I202V, Q207K, R211K, F214L, P243T, V245Q, A272P, K275R, Q278N, T286A, E291D, V292I, I329VC
 TJC2385322TJC2385322 AZT, 3TCEFVM184V, L210WK103N, K238NV35T, E36A, T39E, E40D, S48T, K104R, V118I, K122E, D123S, E138A, T139A, I142IT, T165L, K173T, Q174K, Q197K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E308K, I309V, L310C, P313Q, V317AC
 23628782362878 AZT, 3TCEFVD67N, K70R, M184V, T215F, K219QA98G, K101E, V106M, F227LK20R, V35I, T39D, E40D, S48T, T69TN, D86DE, W88S, K103R, L109I, V118VI, D121H, K122E, E138A, I142V, K173A, D177E, I178L, T200A, I202V, E204K, Q207E, R211K, F214L, V245Q, E248N, D250DN, A272P, T286A, E291D, V292I, I293VC
 22805242280524 D4T, 3TCEFVM184VK101KE, K103N, V106VMK20R, V35A, E36A, T39D, S48T, V60I, K122E, D123G, E138A, K173A, Q174K, T200A, Q207D, R211K, P236PS, V245Q, A272P, E291D, V292I, I293VC
 23499842349984 D4T, 3TCNVPK65R, V75I, F116Y, Q151M, M184VK101E, G190A, F227LV35T, T39E, S48T, V60I, S68G, V118I, K122E, D123S, I132L, E138A, T139A, K173T, Q174K, D177E, V179I, T200A, I202V, E204D, Q207E, R211K, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, V317A, I329LC
 23006882300688 D4T, 3TCEFVA62V, M184VK103N, V106MK20KR, K22R, V35T, E36A, T39E, S48T, W88C, K122E, D123N, I135T, E138A, S162A, T165I, K173T, D177E, I178L, V179VI, T200A, Q207E, R211K, F214L, V245Q, A272P, Q278QH, K281R, T286A, E291D, V292I, I293V, V317AC
 GT00470140GT00470140 D4T, 3TCEFVD67N, M184V, T215F, K219QK101E, G190SV35T, T39E, K122E, D123N, I135L, E138A, K173A, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, R284K, E291D, V292I, I293VC
 TJG4836353TJG4836353 D4T, 3TCEFV  V35T, E36EA, T39DN, S48T, V60I, K122E, E138A, R143RK, T165I, K173AT, Q174K, G196E, Q207E, V245Q, A272S, K277R, T286A, E291D, V292I, I293VC
Deshpande (2010)68IND45168IND451GU108177AZT, 3TCNVPM41L, D67N, K70R, L74I, M184V, T215F, K219QA98G, K103N, K238TV35T, T39D, S48ST, V60I, K122E, D123N, I135L, E138A, I142V, S162SN, L168LV, Q174K, N175Y, T200E, Q207A, R211K, L228LH, V245QC
El-Khatib (2010)Pat01610ZA_SAVE1216HQ012294D4T, 3TCEFVD67N, M184VK103NV35T, E36EA, T39E, S48T, V60I, W88C, V118I, K122E, D123G, I135T, E138A, T139A, I142T, T165TI, K173T, Q174K, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250NC
 Pat01910ZA_SAVE1279HQ012297AZT, 3TCEFVM184VK103N, P225PHV35T, T39E, S48T, A98S, K122E, D123S, E138A, I142RS, T165L, K173T, Q174K, T200A, I202V, Q207A, R211K, V245Q, D250EC
 Pat02810ZA_SAVE1419HQ012306D4T, 3TCEFV K103NK20R, V35T, E36A, T39E, W88C, K122E, D123N, E138A, K166KR, K173T, Q174QR, D177EG, T200A, Q207E, R211K, F214L, V245QC
 Pat03010ZA_SAVE1500HQ012308D4T, 3TCNVPM184VK101E, V106M, F227FLK13KN, V35T, E36A, T39E, S48T, K122E, D123DG, E138A, S162C, K173A, Q174K, T200A, E204D, Q207D, R211K, V245K, E248D, K249QC
 Pat03910ZA_SAVE2156HQ012317AZT, 3TCEFVK219QK103NV35T, E36A, T39E, S48T, V60I, K122E, E138A, S162C, K173A, Q174K, T200A, Q207A, Y232H, V245QC
 Pat04410ZA_SAVE2201HQ012322D4T, 3TCEFVM184VK103N, Y188LV35T, E36A, T39D, S48T, K122E, E138A, I142V, S162A, E169Q, K173I, Q174K, T200A, I202V, Q207E, R211T, V245H, E248DC
 Pat05510ZA_SAVE2324HQ012333AZT, 3TCEFVV75I, M184MIVL100I, K101KE, V106M, G190GAK22R, I31L, V35T, T39A, E40D, S48T, K64R, W88S, V90VI, V118I, K122E, E138A, T165I, K173I, Q174K, T200A, Q207E, R211K, F214L, H221HY, V245Q, E248NC
 Pat06110ZA_SAVE2368HQ012339D4T, 3TCEFV K103NV35T, T39E, S48T, K104R, K122E, E138A, S162W, E169A, K173E, D177N, T200A, Q207E, R211K, F214L, H221HY, Y232H, V245QC
 Pat07110ZA_SAVE2452HQ012349D4T, 3TCEFVM184VK103N, P225HK20R, E28EQ, V35T, T39E, S48T, K122E, I135L, E138A, K173A, T200A, E204K, Q207E, R211K, F214L, V245Q, E248DC
 Pat07510ZA_SAVE2491HQ012353D4T, 3TCEFVA62AV, M184VV106M, V179E, F227FLV35T, T39E, S48T, E53D, V118I, K122E, D123N, I135T, E138A, Q145H, K173T, Q174R, T200A, Q207G, R211K, F214L, V245Q, E248DC
 Pat08411ZA_SAVE1380JF960534NRTI, TDF, AZTNNRTI K103NV35T, T39E, S48T, Q85P, K102R, K104R, K122E, D123N, E138A, T139A, K173M, Q174K, T200A, Q207A, R211K, V245Q, E248D, A272P, K275R, K277R, Q278HC
 Pat09411ZA_SAVE2003JF960544NRTI, AZT, DDINNRTI K103KNV35T, E36A, T39E, S48T, K122E, D123DGNS, E138A, I142IT, K173A, Q174K, T200A, Q207X, R211K, V245Q, E248D, A272P, K277RC
 Pat09811ZA_SAVE2040JF960548NRTI, AZT, DDINNRTIM184IK103N, P225H, M230LV35T, E36A, T39D, S48T, K122E, E138A, I142V, S162A, K173T, T200A, Q207K, R211Q, F214L, D250E, A272P, K277RC
 Pat11611ZA_SAVE2358JF960566NRTI, AZT, DDINNRTIM184MVK103N, P225HV35T, T39E, S48T, V60I, K122E, D123G, E138A, K173A, Q174K, T200A, Q207E, R211K, V245Q, A272PC
 Pat12411ZA_SAVE2438JF960574NRTINNRTI  V35T, E36A, T39E, S48T, K122E, D123G, E138A, K173A, T200AE, Q207G, R211K, V245Q, D250E, A272P, K277RC
Green (2011)707PKE10F707PKE10FHM623501D4T, 3TCEFV  K20KR, V35T, T39E, S48T, K122E, D123G, E138A, K173A, Q174K, D177G, V179I, T200AE, Q207A, R211K, V245Q, A272P, K277KR, K281KR, T286A, E291D, V292I, I293VC
 707PKE23F707PKE23FHM623512D4T, 3TCEFVM184VK103N, P225HV8I, V35T, T39N, S48T, V60I, K101Q, K122E, I135T, E138A, K173A, Q174K, G196E, T200A, I202IV, Q207E, R211K, F214L, L228LI, V245Q, E248ED, A272P, E291D, V292I, I293V, K311RC
Sigaloff (2011)GP25416072GP25416072_1JN381561D4T, 3TCEFV  V35T, E36L, T39E, D121DH, K122E, D123S, I135T, E138A, S162C, K173A, D177E, T200A, Q207AV, R211K, V245Q, A272P, T286A, E291D, V292I, I293VC
 GT00011000GT00011000_1JN381563D4T, 3TCEFVM41ML, M184V, T215YK103NV35T, T39AE, E42EK, S48T, V60I, D76X, K101Q, K122E, D123S, I135L, E138A, R172RM, K173A, I178L, S191Y, T200A, Q207K, R211K, V245Q, A272P, E291D, I293V, E308XC
  GT00011000_2JN381564D4T, 3TCEFVD67N, M184V, K219QK103N, Y318FV35T, T39E, S48T, V60I, K122E, D123S, I135L, E138A, K173A, I178L, T200A, Q207T, R211K, V245Q, I257IL, A272P, T286A, E291D, I293V, L295I, E308D, I309~C
 GT00328364GT00328364JN381604D4T, 3TCEFVM184VK103NT7TA, V35T, T39K, V90VI, K122E, D123N, I132L, I135T, E138A, T139A, S162C, K173A, Q174K, D177E, I178M, T200A, Q207E, F214L, P243S, V245Q, R284K, T286AC
van Zyl (2011)A119A119JN638077D4T, 3TCEFV  V35T, E36A, T39E, S48T, K122E, D123N, E138A, S162T, K173V, Q174K, T200A, Q207A, R211K, V245Q, E248DC
 A194A194JN638115D4T, 3TCEFV  V35T, E36A, T39E, S48T, V60I, K122E, D123S, E138A, A158S, K166R, K173A, Q174E, T200A, Q207E, R211K, F214L, H221Y, V245QC
 A80A80JN638225AZT, 3TCNVPK70T, M184VV106M, F227LP9S, V35T, T39K, S48T, S68G, K122E, D123N, E138A, K173T, Q174K, D177N, T200A, I202V, Q207V, R211K, F214L, V245Q, E248DC
Brehm (2012)24ZA24ZA.48JN601944D4T, 3TCNVPM184V, N348IK103NV35T, E36A, T39D, S48T, K122E, D123G, I135T, E138A, S162A, K173T, T200A, Q207D, R211K, D250E, A272P, K275Q, Q278H, T286A, E291D, V292I, I293V, P294S, Q334H, G335D, R356K, G359T, K366R, T369A, T377L, K390R, E399G, A400T, E404D, N447I, L452I, V467I, T470S, D471E, T477A, H483Q, L491S, L517X, S519N, K527N, K530R, V531I, A534S, A554SC
  24ZA.60JN601945D4T, 3TCNVPV75VI, M184V, N348NIK103NV35T, E36A, T39D, S48T, K122E, D123G, I132IL, I135IT, E138A, S162A, K173T, T200A, Q207D, R211K, D250E, A272P, K275Q, Q278H, T286A, E291D, V292I, I293V, P294S, Q334H, G335D, R356K, G359T, K366R, T369A, T377L, K390R, T397TA, E399EG, A400T, E404D, N447I, L452I, V467I, T470S, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554SC
Jones (2012)198227198227JN671111NRTINNRTIM41L, D67N, L210W, T215Y K20R, V35T, T39E, V118VI, I135T, E138A, I142T, Q151QR, G152GE, P170PL, R172K, K173I, Q174K, D177E, T200A, E203K, Q207A, H208HY, R211K, K223KE, V245Q, E248ED, A272P, K277R, Q278H, E291D, V292I, I293V, S322A, G333E, Q334C, R356K, G359T, V365VI, S379A, K390R, E396D, T397VC

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