<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K103N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 54
Isolates 60
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)IL48IL48AY901738AZT, DDI, DDCNoneM184VA98AG, K103NT39E, S48T, K122E, D123G, S162A, K173A, D177E, G196K, T200A, Q207N, R211K, F214FL, V245QC
Van Zyl (2013)704711.ZA.EC103KC423712AZT, 3TC, DDINoneM184V, T215YK103NE6ED, K20R, V35T, E36EA, T39K, S48T, V60I, K122E, D123S, I135V, I142V, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, V241I, I244IV, V245QC
 43710.ZA.WC074KC423026AZT, 3TC, DDINoneM184VK103NV35T, E36A, T39E, S48T, A98S, K122E, D123G, K173A, D177E, I178L, T200A, E204K, Q207D, V245QC
 33711.ZA.WC155KC423504TDF, 3TCNoneM184MVK103NV35T, E36A, T39D, S48T, K122E, D123G, E138A, K173A, Q174K, T200A, Q207E, R211K, F214L, V245QC
 74311.ZA.WC130KC423372D4T, 3TCNoneM184VK103NV35T, E36A, T39D, K102KR, K173T, Q174K, D177E, T200A, Q207E, R211K, V245QC
 705112.ZA.EC151KC423764TDF, 3TCNoneM184VK103NV35K, T39E, S48T, K101Q, K122KE, I135IM, K173T, Q174K, T200A, E203D, Q207A, R211K, V245N, E248D, D250EC
 405211.ZA.GT1874KC423649AZT, DDINone K103NI5V, K22R, V35T, T39E, S48T, K102R, K122E, D123N, S163T, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245QC
 395712.ZA.GT2066KC423774ABC, 3TCNoneM184IK103NP4T, V8I, K20R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, T165I, K173A, Q174K, D177E, V179I, T200A, Q207A, R211K, F214L, V245QC
 342810.ZA.GT1108KC422948D4T, 3TCNoneT215PK103NV35T, E36A, T39E, S48T, V60I, V118I, D123E, E138D, K173A, Q174K, D177E, I178M, T200A, Q207D, R211K, F214LC
 292410.ZA.GT1232KC423062D4T, 3TCNoneM184VK103NV35T, E36A, T39E, S48T, V60I, K173A, Q174K, D177E, T200A, Q207A, P243S, V245Q, E248DC
 92709.ZA.WC043KC424330AZT, 3TC, DDINone K103NK22KR, V35T, E36EA, T39E, S48T, E53D, W88WCS, K122E, E138A, K173A, Q174K, G196V, T200A, Q207E, R211K, F214L, V245QC
 182007.ZA.GT275KC424081AZT, 3TCNoneM184VK103NK20KR, V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, T165L, K173T, T200A, Q207A, R211RK, V245QC
 42712.ZA.MP001KC423906AZT, DDINoneV75I, M184VK103N, V108II31L, V35T, V60I, K122E, D123N, K173A, Q174R, D177E, T200A, I202V, Q207E, R211K, V245EC
 255511.ZA.GT1556KC423340ABC, AZTNone K103N, V108VIV35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178L, Q197K, T200A, Q207DEG, R211RK, V245KC
 169807.ZA.GT114KC423018AZT, DDINone K103NK20R, V35T, E36A, T39E, S48T, K122E, D123S, E138A, S162A, K173A, Q174KN, D177G, T200A, Q207D, R211K, V245QC
 702307.ZA.GT330KC424117AZT, DDINone K103NV35T, E36A, T39E, S48T, K122E, D123S, S162C, K173T, D177E, I178L, T200AV, Q207A, R211K, V245QC
 533712.ZA.GT2076KC423781AZT, DDINone A98G, K103NV35T, E36A, T39E, S48T, K122E, D123N, R125K, K166R, K173A, D177E, T200A, E204K, Q207E, F214L, V245QC
 399610.ZA.GT1473KC423258AZT, DDINone K103NV35T, T39D, S48T, E53D, V60I, K122E, D123S, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, D250EC
 184109.ZA.GT858KC424356AZT, DDINone K103NK20R, V35T, E36A, T39E, K122E, K166R, K173A, D177E, T200A, Q207E, R211K, F214L, V245QC
 59709.ZA.WC046KC424339AZT, DDINoneT215FA98G, K103NV35T, T39D, S48T, E53D, K122E, D123S, I135L, S162C, K173A, I178L, G196E, T200A, Q207E, R211K, L228Q, V245Q, E248DC
 293109.ZA.GT750KC424275AZT, 3TCNoneM184VK103NK32R, V35K, T39E, S48T, K122E, D123S, I135M, S162C, K173A, Q174K, D177E, T200A, R211K, V245Q, K259SC
 21312.ZA.EC187KC423853AZT, 3TCNoneM184VK103NE6D, V35T, E36A, T39E, S48T, W88C, K102Q, K122E, D123S, I142V, I159V, K173T, Q174K, T200A, I202V, Q207K, R211A, F214L, V245QC
 289509.ZA.GT851KC424349AZT, 3TC, DDINone K103NE28EK, E29EK, V35T, T39A, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, Q207K, R211K, F214L, V245QC
 36710.ZA.GT1362KC423175AZT, 3TC, DDINoneM184VK103NE28A, V35T, T39A, S48T, V60I, A98S, K122KE, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250EC
 373310.ZA.GT1292KC423124ABC, D4T, 3TCNoneM184IK103NP4S, V35T, E36A, T39E, S48E, D123E, K173A, Q174K, D177E, G196E, T200A, Q207E, R211K, F214L, V245Q, D250EC
 72412.ZA.WC209KC423815D4T, 3TCNoneM184VK103NV35T, E36A, T39E, S48T, V90I, K122E, D123S, I135T, T165I, T200A, Q207E, R211K, F214L, V245QC
 199810.ZA.GT1374KC423185AZT, 3TC, DDINone K103NK20R, V35T, T39E, S48T, K122E, E138A, K166R, K173AV, Q174K, D177E, G196M, T200A, I202V, R211K, V245QC
 41712.ZA.EC172KC423811TDF, 3TCNoneD67DN, K70KR, M184V, T215TFISA98G, K103NE6K, K11KQ, V35T, E36A, T39E, S48T, V60I, K122E, D123G, Y127X, K173A, D177E, T200A, Q207E, R211K, V245QC
 702409.ZA.GT660KC424227AZT, 3TCNone K103NP4S, V35T, E36EA, T39R, S48ST, V60VI, K64KR, T69TS, K122E, D123GS, S162SC, K173AV, Q174KT, D177E, T200A, Q207DE, R211K, V245EQC
 60111.ZA.EC038KC423456AZT, DDINone K103NV35T, T39E, S48T, V60I, K122E, D123G, I142K, K166R, K173A, Q174R, T200E, Q207A, R211K, V245KC
 251910.ZA.GT1066KC422911AZT, DDINone K103NV35T, T39EK, S48T, V60I, K102KR, K122E, D123S, T139A, K166R, K173A, Q174R, D177E, T200A, I202V, Q207E, R211KC
 371810.ZA.GT1063KC422908D4T, 3TCNoneM184VK103NK20R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123G, K166R, K173A, D177E, I195L, T200A, Q207E, R211K, V245QC
 190411.ZA.GT1698KC423495AZT, DDINoneT215FA98G, K103NK20R, V35T, T39E, S48T, V60I, K102R, K122E, D123G, I135L, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245QC
 247810.ZA.GT1154KC422992AZT, 3TCNoneM184VA98G, K103NK20R, V35T, E36A, T39E, E40D, S48T, V60I, W88C, K122E, D123N, I135L, S163T, K173T, Q174K, T200A, Q207E, F214L, V245EC
 316307.ZA.GT128KC423098AZT, DDINone K103NP4S, V35T, E36A, T39E, S48T, W88S, K122E, D123G, S162A, D177E, T200A, Q207E, V245Q, D250EC
  08.ZA.GT392KC424154AZT, DDINone K103NP4S, V35T, E36A, T39E, S48T, W88WS, K122E, D123G, S162A, D177E, T200A, Q207E, V245Q, D250EC
 298409.ZA.GT843KC424346D4T, DDINone K103NV35T, E36V, T39E, S48T, V60I, K122E, D123G, I135T, S163T, T165I, K173A, D177E, T200A, Q207A, F214LC
 250707.ZA.GT277KC424079AZT, DDINone K103NK11Q, V35K, E36A, T39E, S48T, V118VF, K122E, D123G, S162C, K173A, D177E, T200A, Q207E, R211K, V245QC
  08.ZA.GT496KC423691AZT, DDINone K103NK11Q, V35K, E36A, T39E, S48T, E53EK, K122E, D123G, S162C, K173A, D177E, T200A, Q207E, R211K, V245QC
  08.ZA.GT529KC423794AZT, DDINoneT215NK103NK11Q, V35KR, E36A, T39E, S48T, K122E, D123G, S162C, K173A, D177E, T200A, Q207EK, R211K, V245QC
 355610.ZA.GT1133KC422961D4T, 3TCNoneM184VK103N, V108IK20R, V35T, T39A, S48T, V60I, K122E, D123G, I135T, K173A, D177E, T200A, Q207E, R211K, V245Q, E248D, D250EC
  11.ZA.GT1591KC423379D4T, 3TC, ABCNoneM184VK103N, V108IK20R, E28EK, K32KE, V35T, T39TAEK, S48T, V60I, K102KQ, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, V245Q, E248D, D250EC
 346008.ZA.GT623KC424196D4T, 3TCNone K103N, V108VIK32N, V35T, E36A, T39E, S48T, K102KR, K122E, D123N, S163T, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245QC
  10.ZA.GT1207KC423039D4T, 3TC, AZT, DDINone K103NI5V, K22R, V35T, E36A, T39E, S48T, K102R, K122E, D123N, S163T, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245QC
 163308.ZA.GT433KC423360D4T, DDINone K103NV35T, T39D, S48T, V60I, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245QC
 204607.ZA.GT228KC424054AZT, DDINone K103NV35T, T39E, S48T, V60I, K122E, D123DG, R172W, K173A, T200A, I202IV, Q207AEKT, R211K, V245QC
  07.ZA.GT333KC424130AZT, DDINone K103NV35T, T39E, S48T, V60I, K122E, K173A, T200A, I202IV, E204EQ, Q207A, R211K, V245QC
Grossman (2014)751751 TDF, DDINone K103NT39E, K43R, K122E, D123S, K173A, D177E, E204Q, Q207A, R211K, V245QC
Steegen (2014)12ZAKS36012ZAKS360KJ176639D4T, 3TCNoneM184VK103NP4S, K20R, V35T, E36A, T39D, A98AS, I135L, E138Q, S162A, K173T, T200A, Q207E, R211K, D250E, I270S, K277KR, K281KR, E291D, V292I, I293V, H315Y, V317A, I329L, Q334N, G335D, R356K, G359T, T377L, K390R, A400T, E404DC
 11ZAKS16211ZAKS162KJ176444D4T, 3TCNoneA62AV, V75T, M184VK103N, V108II31L, V35I, T39KN, S48T, E53D, V118I, K122E, D123G, K173T, Q174K, D177EG, T200A, I202V, Q207A, R211K, H221Y, V245Q, A272P, E291D, V292I, I293V, I309X, K311R, D324EC
 12ZAKS28212ZAKS282KJ176561D4T, 3TCNoneD67N, K70R, M184V, K219EQK103NV35T, E36A, T39E, K43Q, V60I, K102KQ, K122E, D123G, K173T, Q174K, D177E, G196E, T200A, E203K, Q207E, V245E, A272P, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, M357R, G359T, A360T, T377Q, K390R, A400I, E404DC
 11ZAKS15711ZAKS157KJ176439D4T, 3TCNoneD67N, M184VK103NP4T, K20R, V35T, T39E, S48T, K122E, D123N, A158S, K173A, Q174K, D177E, G196K, T200A, Q207A, R211K, V245M, D250E, A272P, E291D, I293V, I326V, G335DC
Neogi (2016)77813.ZA.WC375KT593549AZT, 3TCNoneL74V, M184VK103N, V108IP4S, V35T, T39E, S48T, K122E, Q174R, D177E, I178M, G196V, T200A, Q207E, R211K, F214L, V245QC
 251513.ZA.GT3116KT593363AZT, 3TCNoneM184VK103NE28EK, K32Q, V35T, T39E, S48T, K122E, D123N, I135T, S162C, K173A, Q174R, D177E, I178L, T200A, Q207A, R211K, V245Q, E248D, D250DE, K259SC
 79513.ZA.WC292KT593494D4T, 3TCNoneM184VK103NE28A, V35T, T39E, S48E, K122E, D123S, K166R, K173A, D177E, T200A, I202V, E204K, Q207G, R211Q, V245QC
 13313.ZA.EC681KT592839AZT, 3TCNone K103NI2IV, V35R, T39D, S48T, W88C, K122E, D123N, I135L, I142T, S162W, T165I, K173A, Q174K, I178M, G196E, T200R, Q207E, R211K, F214L, L228Q, V245QC
 101613.ZA.WC321KT593515AZT, 3TCNoneV75VL, F77FL, M184VK103N, V108VIV35M, T39E, S48T, K122E, K173A, Q174K, D177E, E203Q, Q207D, R211K, V245Q, D250DEC
 220613.ZA.GT2709KT593074AZT, 3TCNoneM184VA98AG, K103NV35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, T200A, Q207A, F214L, V245QC
 249013.ZA.GT3134KT593379TDF, 3TCNoneM184MIVK103NK20KR, V35T, E36A, T39D, S48T, W88F, K102H, K122E, E138Q, S162CY, K173A, D177E, I178L, T200A, E204K, Q207D, R211K, F214L, P243PST, V245Q, D250EC
 214113.ZA.GT2836KT593173TDF, 3TCNoneD67N, M184V, T215YK103NV35T, T39E, S48T, A98S, K122E, D123E, I135V, K166R, K173A, D177E, T200A, Q207K, R211T, H221HY, V245QC