<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K103N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)IL48IL48AY901738AZT, DDI, DDCNoneM184VA98AG, K103NT39E, S48T, K122E, D123G, S162A, K173A, D177E, G196K, T200A, Q207N, R211K, F214FL, V245QC
Van Zyl (2013)16212755KC423815D4T, 3TCNoneM184VK103NV35T, E36A, T39E, S48T, V90I, K122E, D123S, I135T, T165I, T200A, Q207E, R211K, F214L, V245QC
 14822669KC423774ABC, 3TCNoneM184IK103NP4T, V8I, K20R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, T165I, K173A, Q174K, D177E, V179I, T200A, Q207A, R211K, F214L, V245QC
 16311742KC423372D4T, 3TCNoneM184VK103NV35T, E36A, T39D, K102KR, K173T, Q174K, D177E, T200A, Q207E, R211K, V245QC
 11211187KC422948D4T, 3TCNoneT215PK103NV35T, E36A, T39E, S48T, V60I, V118I, D123E, E138D, K173A, Q174K, D177E, I178M, T200A, Q207D, R211K, F214LC
 7181328KC423062D4T, 3TCNoneM184VK103NV35T, E36A, T39E, S48T, V60I, K173A, Q174K, D177E, T200A, Q207A, P243S, V245Q, E248DC
 13491140KC422908D4T, 3TCNoneM184VK103NK20R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123G, K166R, K173A, D177E, I195L, T200A, Q207E, R211K, V245QC
Grossman (2014)751751 TDF, DDINone K103NT39E, K43R, K122E, D123S, K173A, D177E, E204Q, Q207A, R211K, V245QC
Steegen (2014)12ZAKS36012ZAKS360KJ176639D4T, 3TCNoneM184VK103NP4S, K20R, V35T, E36A, T39D, A98AS, I135L, E138Q, S162A, K173T, T200A, Q207E, R211K, D250E, I270S, K277KR, K281KR, E291D, V292I, I293V, H315Y, V317A, I329L, Q334N, G335D, R356K, G359T, T377L, K390R, A400T, E404DC
 11ZAKS16211ZAKS162KJ176444D4T, 3TCNoneA62AV, V75T, M184VK103N, V108II31L, V35I, T39KN, S48T, E53D, V118I, K122E, D123G, K173T, Q174K, D177EG, T200A, I202V, Q207A, R211K, H221Y, V245Q, A272P, E291D, V292I, I293V, I309X, K311R, D324EC
 12ZAKS28212ZAKS282KJ176561D4T, 3TCNoneD67N, K70R, M184V, K219EQK103NV35T, E36A, T39E, K43Q, V60I, K102KQ, K122E, D123G, K173T, Q174K, D177E, G196E, T200A, E203K, Q207E, V245E, A272P, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, M357R, G359T, A360T, T377Q, K390R, A400I, E404DC
 11ZAKS15711ZAKS157KJ176439D4T, 3TCNoneD67N, M184VK103NP4T, K20R, V35T, T39E, S48T, K122E, D123N, A158S, K173A, Q174K, D177E, G196K, T200A, Q207A, R211K, V245M, D250E, A272P, E291D, I293V, I326V, G335DC