<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101R
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 7
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Yahi (2001)NY_M1M1AY010449AZT, 3TCNoneM184VE138KV35T, E36A, T39D, K43KE, R83K, F87FL, E89X, K101R, K102R, K122V, D123G, K173A, D177E, G196K, T200A, I202V, Q207G, R211K, L228LVC
Soares (2003)BR56BR56AY275793DDC, AZT, 3TC, D4T, DDINone  I50L, G51A, K101R, K122E, D123S, T200A, Q207E, R211KC
Deshpande (2009)Pat170104RTFJ530771AZT, 3TCNone  V35T, E36A, T39D, S48T, V60I, K101R, D121Y, K122E, F124FS, S162A, K173A, D177E, T200A, Q207E, R211RGC
 Pat034352RTFJ530907AZT, 3TCNoneM41L, D67N, T69D, M184V, T215Y V35K, T39D, E44D, S48T, V60I, K101R, K102KN, D121Y, K122E, I135T, S162A, K173A, Q174R, D177DE, T200A, E203D, Q207E, R211K, L228Q, V245QC
Green (2011)707PKE40F707PKE40FHM623527D4T, 3TCNoneM184VY181YCT27TS, V35T, E36A, T39E, E40D, K101R, K122E, D123N, I135T, T139A, D177E, T200A, Q207E, F214L, P243T, V245Q, A272S, T286A, E291D, V292I, I293V, P294T, D324EC
Grossman (2014)11651165KF134957AZT, 3TCNone  T39E, S48T, K101R, K122E, D123N, K166R, K173A, D177E, T200A, Q207E, R211K, V245QC
  1165KF134958AZT, 3TC, D4TNone  T39E, S48T, K101R, K122E, D123N, K166R, K173A, D177E, T200A, Q207E, R211K, V245QC
 16251625KF134990TDF, FTCNone  T39E, S48T, A98S, K101R, K122E, D123G, K173A, Q174K, D177E, I202IK, Q207A, R211K, G213GE, H221HQ, H235HQ, D237DE, V245QC