<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101Q
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 8
Patients 16
Isolates 16
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Johnston (2003)TC-71TC-71 DDI, AZT, 3TCNoneA62V, K65R, F116Y, Q151M, M184V V8I, V35T, T39E, V60I, S68R, W88S, K101Q, K122E, D123S, I135T, E138A, K173T, Q174K, V179I, T200A, Q207E, R211K, F214L, V245Q, E248DC
Non-B Workgroup (2005)IL92IL92AY901744AZT, 3TCNone  T39E, E40D, K43KE, I47N, S48FL, A98S, K101Q, K122E, D123G, K166R, K173A, D177EG, T200A, Q207E, V245QC
Pillay (2008)DR8103ZA.DR81AY589925D4T, DDINoneM41L, D67N, T215Y K11Q, V35T, T39E, S48T, V60I, K101Q, V118I, D121Y, K122E, D123G, I142V, S162C, K166R, K173A, D177E, T200A, Q207E, R211KC
Rodrigues (2010)323_07BR07SC323GQ401320AZT, 3TCNone  V35T, E36A, T39D, S48T, K101Q, K122E, D123G, I135L, E138G, T139A, A158S, K173A, D177E, T200A, Q207K, R211KC
Van Zyl (2013)705112.ZA.EC151KC423764TDF, 3TCNoneM184VK103NV35K, T39E, S48T, K101Q, K122KE, I135IM, K173T, Q174K, T200A, E203D, Q207A, R211K, V245N, E248D, D250EC
 65111.ZA.EC037KC423455ABC, 3TCNone  K32E, V35T, E36A, T39E, S48T, K64KR, T69TN, K101Q, K122E, D123G, I135K, S162N, K173A, D177E, T200A, Q207E, R211K, V245QC
Steegen (2014)12ZAKS23512ZAKS235KJ176514D4T, 3TCNoneD67N, M184V V35K, T39E, S48E, K101Q, K173A, D177E, T200A, Q207R, R211K, V245Q, E291D, V292I, I293V, I326V, Q334DC
 12ZAKS19512ZAKS195KJ176476D4T, 3TCNoneD67N, M184V V35K, T39E, S48E, K101Q, I135IV, K173A, D177E, T200A, Q207R, R211K, V245Q, K277KR, E291D, V292I, I293V, I326V, Q334D, I341V, R356K, M357K, G359S, T377M, K390R, A400T, T403M, E404DC
Neogi (2016)322713.ZA.GT2920KT593231AZT, 3TCNoneK70R, K219KQA98G, Y181CV35T, E36A, T39E, S48T, T69N, K101Q, K122E, K173A, Q174K, D177E, T200A, Q207T, R211K, F214L, L228R, V245Q, D250EC
Posada Cespedes (2017)125514.ZA.EC1402KX544000TDF, 3TCNoneM184VK103N, V108VIK20R, V35T, T39E, V60I, K101Q, K122E, D123G, D177E, I178M, T200A, E204K, Q207A, R211K, V245QC
 185414.ZA.GT3474KX544333AZT, DDINoneD67N, K70R, K219QK103NV35T, E36A, T39E, S48T, V60I, K101Q, K122E, D123G, K166R, K173A, D177E, T200A, Q207E, R211K, V245QC
 522714.ZA.WC405KX544678ABC, 3TCNone  K22R, V35T, E36A, T39E, K101Q, K122E, D123G, I135K, S162SADY, K173A, Q174K, V179I, T200A, Q207A, R211K, V245QC
 45813.ZA.WC344KX543611AZT, 3TCNoneV75VME138KP4PS, V35T, T39E, E40ED, S48T, V60I, K101Q, K122E, D123G, K173A, T200A, I202IV, Q207EG, R211K, F214L, V245QC
 57213.ZA.EC811KX542831ABC, 3TCNone  V35T, E36A, T39E, E42EG, S48T, K101Q, K122E, D123G, E138A, S162C, K173A, Q174R, D177G, V179I, T200A, Q207E, V245Q, E248DC
 718715.ZA.EC1705 TDF, 3TCNoneM184MVK103KNV35T, T39EK, S48T, V60VI, K101Q, K122E, D123S, I135KR, S162A, K173A, D177E, T200A, Q207E, R211K, V245QC
 440115.ZA.WC592 AZT, 3TCNoneM184VA98AG, G190AV21I, V35T, E36A, T39E, S48T, V60I, W88C, K101Q, K122E, D123G, K173A, D177G, T200A, E203K, Q207E, R211K, V245QC