<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 15
Patients 24
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2001)SE73SE73AF388136NoneNVP K103KNV35T, E36A, T39E, E40D, K43R, S48E, E53D, K101Q, K122E, D123G, E138A, S162Y, K173A, D177G, V179I, G196E, T200A, Q207D, V245Q, T253TP, A272P, K277R, T286A, E291D, V292I, K311RC
Eshleman (2004) SE73_7dAY428676NoneNVP K103KN, V106VAV35T, E36A, T39E, E40D, K43R, S48E, E53D, K101Q, K122E, D123DG, E138A, S162Y, K173AT, D177G, V179I, G196E, T200A, Q207DN, V245Q, A272P, K277R, T286A, E291D, V292I, K311R, Q334EC
Non-B Workgroup (2005)TK1020TK1020b AZT, DDI, 3TC, ABCEFVM41L, D67N, L74V, M184V, T215YK103NV35R, T39D, E44D, S48ST, K101Q, V118VI, K122E, D123G, K173T, Q174K, D177E, T200A, Q207E, L210S, R211K, D218E, V245Q, A272P, K277R, V292I, I293V, E297AC
Sen (2007)T073NPT73-PLEF186964D4T, 3TCNVPM184VG190AV35T, T39D, S48T, V60I, K101Q, K122E, I135T, E138G, K166R, K173A, G196E, T200A, Q207G, R211K, V245Q, D250E, A272P, K277R, K281KR, E291D, V292I, I293V, Q334E, G335D, R356K, G359T, E370ED, T377R, S379C, I382IV, K390R, A400TC
 T006NPT6-PLEF186984AZT, 3TCNVPD67N, T69DN, K70R, M184V, T215F, K219EA98G, Y181C, G190AV35T, E36A, T39E, S48T, V60I, K101Q, K104R, D121Y, K122E, I135L, K166R, K173A, D177E, T200A, Q207E, R211K, L228H, V245Q, A272P, K277R, E291D, V292I, I293V, Q334Y, G335D, R356K, G359N, T377M, K390R, E404D, Q428R, K431T, V435A, N447S, L452T, V466I, D471E, H483YC
Marconi (2008)ICH23ICH23EU308013D4T, AZT, 3TCEFVD67N, M184V, K219EK103N, G190AS48T, V60I, V90VI, K101Q, K122E, D123N, I135V, I142T, K173T, D177G, T200A, Q207A, R211K, V245QC
 SW017sw017EU308034D4T, 3TCEFVM184VK103NS48T, V60I, K101Q, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211K, V245QC
 SW042SW042EU308055D4T, DDI, AZT, 3TCEFVM184VV106M, V179VEE40R, S48T, S68G, K101Q, K102R, K104R, K122E, D123S, E138A, K173I, Q174QK, D177DE, T200A, Q207E, R211K, F214L, V245QC
Pillay (2008)DR9303ZA.DR93AY589932D4T, 3TCEFVD67N, T69D, K70R, K219QV106M, V179VD, G190GA, F227FLA33G, V35T, E36A, T39E, K101Q, K122E, D123N, K173A, D177E, Q197L, T200A, Q207E, L228H, V245Q, A272P, K277R, E291D, V292I, I293V, V317AC
Deshpande (2009)Pat2241RTFJ530717D4T, 3TCNVPD67N, K70R, M184V, K219Q V35T, T39D, K43R, V60I, K101Q, D121Y, K122E, I135R, S162A, K173A, D177E, V179I, Q197K, T200A, E203D, Q207QAEP, R211K, V241VI, V245Q, K249NC
 Pat19056RTFJ530751D4T, 3TCEFVM184VV106M, G190A, F227FLV8I, K13N, V35M, T39E, K101Q, D121DY, K122E, I135T, K173A, Q174K, D177E, T200A, Q207EG, R211K, L228LH, V245QC
 Pat17692RTFJ530765D4T, 3TCNVPM184VG190AV35T, T39E, S48T, K101Q, K104R, K122E, D123S, K173A, D177E, T200A, Q207E, R211T, V245QC
 Pat074293RTFJ530867D4T, 3TCNVPD67N, F77L, F116Y, Q151M, M184V, T215YY181C, G190AI2S, K11I, V35T, E36A, T39E, S48T, V60I, K101Q, D121Y, K122E, K166R, K173A, D177E, T200A, Q207E, R211K, H221HY, W239C, V245EC
 Pat009433RTFJ530932D4T, 3TCEFV  V8I, V35T, E36A, T39D, S48T, K101Q, D121C, K122E, S162C, K173T, Q174R, D177E, T200A, Q207E, R211K, V245QC
Hoffmann (2009)pat074MD57113 AZT, 3TCEFVL74LV, M184VK103NI31L, V35T, T39E, S48T, T69TN, A98S, K101Q, D121Y, K122E, D123E, K173I, Q174K, D177E, Q197L, T200A, Q207E, R211K, V245Q, D250E, A272PC
Hosseinipour (2009)94339433GQ228367D4T, 3TCNVPA62V, K65R, V75I, F77L, F116Y, Q151M, M184VY181VT39E, S48ST, E53D, S68G, T69TI, K101Q, V118I, D121HY, K122E, I135T, K173A, Q174K, D177E, T200A, I202V, Q207D, L210F, R211K, F214L, V245QC
Wallis (2009)23450232345023 D4T, 3TCEFVM184VY188LK30KE, V35T, T39K, S48T, V90I, K101Q, K122E, D123S, I135IT, K173A, I178L, V179I, T200A, Q207N, R211K, V245Q, E248EK, A272S, K277R, L283LF, T286TA, E291D, V292I, I293V, L303LWC
El-Khatib (2010)Pat07210ZA_SAVE2469HQ012350D4T, 3TCEFVM184VV106M, Y188HLV35T, T39E, S48T, K101Q, K122E, D123G, K173T, T200A, Q207E, R211K, Y232YH, V245H, S251NC
 Pat09911ZA_SAVE2062JF960549NRTI, AZT, DDINNRTIM184VK103NV8I, V35T, T39A, S48T, V60I, K101Q, K122E, D123G, I135T, K173A, D177E, I178M, T200A, Q207E, V245Q, A272PC
Rodrigues (2010)346_07BR07SC346GQ401328AZT, 3TCEFVM184VK103N, P225HV35K, E36A, T39D, K43R, S48E, V90I, K101Q, K104R, S162A, D177E, T200A, Q207E, R211KC
Green (2011)707PKE23F707PKE23FHM623512D4T, 3TCEFVM184VK103N, P225HV8I, V35T, T39N, S48T, V60I, K101Q, K122E, I135T, E138A, K173A, Q174K, G196E, T200A, I202IV, Q207E, R211K, F214L, L228LI, V245Q, E248ED, A272P, E291D, V292I, I293V, K311RC
Sigaloff (2011)GT00011000GT00011000_1JN381563D4T, 3TCEFVM41ML, M184V, T215YK103NV35T, T39AE, E42EK, S48T, V60I, D76X, K101Q, K122E, D123S, I135L, E138A, R172RM, K173A, I178L, S191Y, T200A, Q207K, R211K, V245Q, A272P, E291D, I293V, E308XC
van Zyl (2011)A182A182JN638107D4T, 3TCEFVD67DN, M184IV106MI31L, V35T, E36A, T39E, S48T, V90VI, K101Q, K122E, D123S, T165I, K173T, D177E, T200A, Q207E, R211KC
 A63A63JN638219D4T, 3TCNVPM184VY188CV35T, E36A, T39E, S48T, V60I, K101Q, K122E, D123G, I135V, K173A, T200A, Q207D, R211K, L228LF, V245QC
 A79A79JN638224D4T, 3TCEFVM184VK103NV8IT, V35T, T39K, S48T, V60I, K101Q, K122E, D123G, I135K, S162SC, E169D, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245QC

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