<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101P
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 31
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Deshpande (2009)Pat062324RTFJ530879NRTINNRTIM184V, T215FK101P, G190AV35T, T39E, S48T, V60I, K102Q, D121Y, K122E, I135T, K166R, K173T, T200A, Q207D, R211K, F214L, D237E, V245QC
Wallis (2009)TJC2443711TJC2443711 D4T, 3TCEFVM184VK101P, K103NK20R, V35T, T39E, S48T, V60I, K122E, D123G, I135IT, E138A, T139A, K166R, K173T, Q174R, I202V, R211K, F214L, V245Q, D250DE, A272P, K277R, T286A, V292I, I293V, E297EK, Q334EC
 TJC2371599TJC2371599 D4T, 3TCEFVM184VK101P, K103NV35T, E36A, T39D, K49R, V60I, K122E, K173T, Q174K, D177E, I178M, V179VI, T200A, Q207E, R211RK, V245Q, A272P, E291D, V292I, E297EKC
 GP00005761GP00005761 AZT, 3TCEFVM41L, D67G, K70R, L74V, M184V, K219QK101P, G190SK20KR, V35T, T39E, S48T, V60I, S68G, K122E, D123GS, I135M, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, L228LH, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E308EK, I309IV, D324EC
Deshpande (2010)35IND43635IND436GU108162D4T, 3TCNVP, EFVM41ML, M184V, T215F, K219K*RWK101P, G190AV35IT, T39E, S48T, V60I, K102Q, D121Y, K122E, I135T, K166R, K173T, T200A, Q207D, R211K, F214L, L228LH, V245QC
van Zyl (2011)A290A290JN638179D4T, 3TCNVPM184VK101P, K103SE28A, K32E, V35K, E36A, T39E, S48T, E53D, K122E, D123S, I135T, T139TS, I142IL, S162H, K173T, T200A, Q207DE, R211K, F214L, V245QC
Van Zyl (2013)5051931KC423518TDF, 3TCNVPD67N, K70KN, F116Y, Q151M, M184VK101P, K103NK22R, V35T, T39E, S48T, E53D, K122E, D123DN, K173I, D177E, I178L, V179I, G196E, T200A, E204K, Q207D, R211K, F214L, V245Q, E248EKC
 14101557KC423229D4T, 3TCEFVM184V, T215YK101P, K103NP4S, V35T, E36A, T39E, K122E, I142K, A158S, K173T, T200A, Q207D, R211K, V245QC
 601366KC424014AZT, D4T, 3TCNVP, EFVD67DN, M184VK101P, K103NSV35T, E36A, T39D, S48T, V60I, K122E, D123G, I142V, K173A, D177E, I178L, V179I, T200A, Q207N, R211K, V245QC
 805396KC424038AZT, D4T, 3TC, ABCNVP, EFVM184VK101P, K103N, P225PHQK20KR, V35T, T39E, S48T, K122E, D123S, K173A, Q174K, D177G, Q197E, T200A, Q207N, R211K, V245Q, D250EC
 15022120KC423633AZT, D4T, 3TC, DDINVP, EFV K101P, K103SV35T, T39E, S48T, V60I, K102KR, K122E, E138A, S162C, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, V245QC
 16431756KC423381TDF, 3TCEFVK65R, M184VK101P, K103NP4T, K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123S, A158S, K173A, Q174K, T200A, Q207E, R211K, F214L, V245QC
 362754KC424267D4T, 3TCEFVM184VK101P, K103NV35T, E36A, T39E, E40D, K122E, D123A, K173T, Q174K, D177E, I178M, T200A, E203D, Q207D, R211K, V245QC
 513134KC423073D4T, 3TCEFVM184VK101P, K103NV35K, T39D, S48T, K122E, D123G, I135L, E138A, K173A, Q174R, D177E, G196T, T200A, R211K, F214FL, V245QC
 6561838KC423450D4T, 3TC, ABCEFVL74V, Y115F, M184VK101P, K103NK20KR, V35K, E36D, T39E, S48T, V60I, K122E, K173A, D177E, T200A, Q207N, R211K, F214L, V245Q, K249QC
 410957KC424394D4T, 3TCEFVM184VK101P, K103NE28EK, V35I, T39DE, S48T, E53D, K122E, D123G, K173T, Q174K, T200A, R211K, V245Q, D250EC
 100998KC424425AZT, D4T, 3TCNVP, EFVM184VK101P, K103NE6EK, K20R, V35T, T39K, K122E, I135V, S162C, K173A, Q174KR, D177E, I178IL, E194ED, T200A, Q207E, R211K, F214L, V245QC
  1556KC423228AZT, D4T, 3TC, ABCNVP, EFVM184VK101P, K103NE6K, K20R, V35T, T39K, K122E, I135V, S162C, K173A, Q174R, D177E, D192DN, T200A, Q207E, R211K, F214L, V245QC
 166609KC424171AZT, 3TCEFVD67N, K70R, M184V, T215TNSY, K219EK101P, K103NV35K, T39D, S48T, V60I, T69N, K122E, D123G, K173T, Q174K, V179VI, T200A, I202IV, Q207K, R211K, V245Q, D250DEC
 5721865KC423466AZT, D4T, 3TC, DDINVP, EFVD67N, T69D, K70R, K219QK101P, K103SK22R, V35T, E36A, T39E, E40D, S48T, V60I, K102R, K122E, D123N, E138G, A158S, K173T, Q174K, V179I, T200A, E203EQ, Q207E, F214L, D218E, L228HC
 1036504KC424100D4T, 3TCEFVM184VK101P, K103NT27A, V35T, E36A, T39E, K122E, D123G, I135T, S162C, K173T, Q174K, D177E, I178M, T200A, Q207E, G231X, E233X, V245Q, D250EC
Steegen (2014)12ZAKS36212ZAKS362KJ176641D4T, 3TCEFVM41L, D67N, V75M, M184V, T215FK101P, K103S, V106ME28A, V35T, T39D, S48T, V60I, K122E, D123G, I135T, K173A, Q174K, D177E, V179VI, T200A, Q207E, R211K, D218E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359S, T377M, S379C, K390R, A400LC
 12ZAKS30412ZAKS304KJ176583D4T, 3TCEFVM184VK101P, K103NV35T, E36A, T39E, S48T, V90I, K102R, K122E, D123S, A158S, E169A, K173A, D177E, T200A, Q207A, R211K, V245Q, D250E, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359S, T369A, K374R, T377L, K388R, K390RC
 11ZAKS11111ZAKS111KJ176393D4T, 3TCEFVM184VK101P, K103NV35T, T39E, S48T, V60I, K122E, D123S, I135R, K166R, K173A, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K275R, K277R, E291D, V292I, I293V, D324DEC
 12ZAKS29612ZAKS296KJ176575ABC, 3TCEFVL74V, M184VK101P, K103NV35T, T39K, K43Q, K102KQ, K104KR, K122E, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, V314A, Q334H, G335D, R356RK, G359T, T377L, K390R, A400T, E404DC
 11ZAKS17011ZAKS170KJ176451D4T, 3TCEFVM184VK101P, K103NSV8I, V35T, T39K, E40D, K102Q, K122E, D123G, K173A, G196K, T200E, E203EK, Q207E, R211RK, V245Q, A272P, T286A, E291D, V292I, K311R, Q334L, G335DC
 12ZAKS34512ZAKS345KJ176624D4T, 3TCEFVM184VK101P, K103NP4S, V35T, T39E, S48T, V60I, V90I, K122E, D123S, I135R, V148L, S162F, K173A, Q174K, Q197E, T200A, Q207G, V245K, A272P, T286A, E291D, V292I, I293V, L301F, P313T, Q334N, G335D, R356K, G359T, K366R, A371V, T377L, K390R, A400T, E404D, V435IC
 11ZAKS10111ZAKS101KJ176383D4T, 3TCEFVM41L, L74V, M184V, L210W, T215YK101P, K103NV35T, T39E, K122E, D123S, I135T, K173A, Q174K, N175NY, D177E, I178IM, T200A, R211K, V245K, A272P, K277R, E291D, V292I, I293V, E308K, I309V, L310CC
 11ZAKS14111ZAKS141KJ176423D4T, 3TCEFVM184VK101P, K103NSV35T, E36A, T39E, S48T, K122E, D123S, K166R, K173A, D177E, T200A, Q207D, R211K, V245Q, E248T, A272P, K277R, K281R, E291D, V292I, I293V, Q334D, G335HC
 12ZAKS32112ZAKS321KJ176600D4T, 3TCEFVM184V, N348IK101P, K103NE28EAKT, V35T, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, Q334H, G335D, R356K, R358K, G359S, T377Q, K390R, A400T, T403S, E404DC
 12ZAKS22712ZAKS227KJ176507D4T, 3TCEFVM184VK101P, V106M, F227FLP4S, V35T, T39E, S48T, E53D, V90VI, K122E, D123S, I135M, E138A, S162HY, K173T, Q174K, V179I, T200A, E203A, Q207E, R211K, F214FL, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, L310I, Q334H, G335DC
 12ZAKS28312ZAKS283KJ176562D4T, 3TCEFVM184V, T215YK101P, K103NT27TS, E28EA, V35T, T39E, S48T, K122E, D123GS, K166R, K173A, D177E, V179I, T200K, Q207A, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, I293V, D324E, G333D, Q334H, R356K, M357I, G359T, D364E, A371AV, T377Q, K390R, A400T, E404D, A408V, E413G, Q428RC