<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101H
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 16
Patients 41
Isolates 43
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)UK1457UK1457AY901339AZT, 3TCNVPM184VK101H, G190AV35T, E36A, T39E, S48T, K122E, D123N, K173T, Q174K, I178L, T200A, Q207E, R211KC
Doualla-Bell (2006)Pt17FDB_Pt17EF434890AZT, 3TC, D4T, DDIEFVM41L, L74LV, V75M, M184MV, T215YK101H, K103N, G190AP4S, V35T, E36A, T39E, S48T, V60VI, V90I, K122E, I135V, S162A, K173A, D177E, Q197K, Q207E, R211K, V245Q, A272P, T286A, E291D, I293V, E297DC
Marconi (2008)SW063sw063EU308074D4T, 3TCEFVD67N, M184VK101H, K103N, G190AS48T, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207D, R211K, V245QC
Hawkins (2009)R347ZZR347FJ931374AZT, 3TCNVPM184V, T215FK101H, G190A, M230LT7A, V35T, T39E, S48T, V60I, D121H, K122E, I135R, S162C, K173T, Q174KR, D177E, V179VI, T200A, Q207E, R211K, V245Q, A272P, K275Q, K277KR, L283I, E291D, V292I, I293V, Q334NC
Hoffmann (2009)pat051MD052585 AZT, 3TCEFVA62V, M184VK101H, K103N, V106MV35T, E36A, T39E, K122E, D123GS, I135T, K173T, D177E, T200A, R211RK, F214L, V245Q, A272PC
Hosseinipour (2009)94029402GQ228335D4T, 3TCNVPM41L, D67N, K70R, M184V, T215F, K219WK101H, Y181IT39E, V60I, T69X, K122E, D123G, I135T, T139I, K173A, V179I, G196K, T200A, Q207E, H208Y, R211K, D218E, L228H, V245QC
 94149414GQ228338D4T, 3TCNVPM184V, T215YK101H, Y181C, G190AT39A, E44ED, S48T, V118VI, K122E, D123S, T139R, K173I, Q174K, D177G, G196E, T200A, Q207E, L210LS, R211RK, F214FL, D218DE, V245QC
 85148514GQ228381D4T, 3TCNVPM41L, D67N, M184V, L210LW, T215FK101H, K103N, G190AT39E, S48T, V60I, K122E, D123S, I135T, K173T, D177DN, T200A, Q207E, D218DE, V245QC
Wallis (2009)TJC2384408TJC2384408 AZT, 3TCEFVM41L, D67N, K70R, V75M, F77L, M184V, L210W, T215Y, K219KQK101H, V106M, G190A, F227LV35I, E36A, T39E, S48T, T69N, K122E, D123N, I135T, K173T, T200A, Q207E, R211K, F214FL, A272P, K275Q, K277R, T286A, A288T, E291D, V292I, I293VC
 TJC2382305TJC2382305 D4T, 3TCNVPM184VK101H, G190AK32N, V35K, E36A, T39E, S48T, V90I, K122E, D123S, I135T, S162F, K173A, Q174K, N175Y, D177E, V179VI, T200A, Q207E, R211K, V245Q, A272P, K277R, T286V, V292I, I293VC
 TJC2389178TJC2389178 AZT, 3TCEFVM184VK101H, G190SV8VA, G18X, V35T, E36A, T39E, S48T, K122E, D123G, E169EA, K173A, Q174K, D177E, V179VAIT, T200A, Q207E, R211K, V245Q, A272P, L279M, E291D, I293VC
 TJG4623653TJG4623653 D4T, 3TCEFVM41L, D67N, K70R, M184V, T215Y, K219EK101H, G190AE6P, V35T, T39E, K103R, K122E, D123G, I135T, S162D, K166R, K173A, D177E, T200A, E204K, Q207E, V245Q, A272P, K277R, T286TA, E291D, V292I, I293VC
El-Khatib (2010)Pat02310ZA_SAVE1379HQ012301D4T, 3TCEFVD67DN, M184VK101H, V106M, G190A, F227FLV35T, T39E, S48T, K122E, D123N, I135IT, A158S, K173A, Q174K, D177E, I195L, G196E, T200A, Q207E, R211K, F214L, Y232YH, P243PS, V245QC
 Pat04610ZA_SAVE2237HQ012324D4T, 3TCEFVM184V, T215FK101H, V106M, P225H, M230LV35T, T39E, K122E, T139A, K173A, Q174K, D177E, E203D, Q207E, R211K, V245K, D250EC
 Pat08311ZA_SAVE1302JF960533D4T, 3TCEFVM184VK101H, K103N, G190AE28K, K32E, V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, G196R, T200A, Q207R, R211K, F214FL, V245Q, A272P, Q278HC
Green (2011)707PKE26F707PKE26FHM623515D4T, 3TCEFVM41ML, K70KR, M184V, K219KRK101H, V106M, G190AP4T, K20KR, V35T, E36A, T39E, V60I, K122E, D123S, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, E248ED, D250NS, A272P, T286A, E291D, V292I, I293V, P313Q, Q334EC
Kouri (2012)CU1913-09CU1913-09JQ585321NRTINNRTID67N, K70R, M184V, T215F, K219EK101H, Y181C, G190SV35T, E36A, T39D, V60I, K122E, D123G, Q174K, D177E, T200A, E203D, Q207KR, R211Q, L228H, V245Q, A272P, K277R, K281R, E291D, V292IC
Manasa (2013)RES174RES174KC951724D4T, 3TCEFVM184VK101H, K103N, G190AV35T, E36A, T39E, S48T, K122E, D123N, K173A, Q174R, D177E, T200A, Q207D, R211K, P243T, V245Q, E248T, A272S, K275Q, E291D, V292I, I293VC
 RES076RES076KC951686D4T, 3TC, TDFEFVD67N, K70G, M184V, K219QK101H, V106M, G190A, F227LV35K, T39E, S48T, V60I, L109I, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, V179I, T200A, Q207K, F214L, V245Q, A272P, K277R, Q278N, E291D, V292I, I293VC
 RES259RES259KC951751D4T, 3TCNVP, EFVM184VK101H, Y181C, G190AV35T, E36A, T39E, S48T, K103R, K122E, T139I, K173T, D177E, T200A, Q207E, R211K, V245K, A272P, K277R, T286A, E291D, V292IC
 RES401RES401KC951826D4T, 3TCEFVD67N, M184VK101H, V106M, F227L, K238TV35T, E36A, T39E, E40D, S48T, V60I, K122E, D123S, D177E, T200A, Q207K, R211A, K219T, V245T, A272P, E291D, V292I, I293VC
 RES071RES071KC951681D4T, 3TCNVPM184VK101H, G190AV35T, T39E, S48T, K122E, D123S, I135T, K166R, K173I, Q174K, I178L, T200A, Q207N, R211K, V245Q, E248T, D250E, A272P, K277R, I293VC
Theys (2013)159400159400 AZT, 3TCEFVD67N, K70R, M184V, K219QK101H, V106M, F227LP9PS, I31V, V35M, T39E, S48T, D123E, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, V245K, E248D, D250E, A272P, E291D, V292I, I293V, V317A, S322LC
Van Zyl (2013)1581971KC424406AZT, D4T, 3TC, TDFNVP, EFVK219QK101H, G190AV35T, T39E, S48T, V60I, K173A, Q174K, D177E, V179I, T200A, Q207E, R211K, V245QC
 12501210KC422963D4T, 3TCEFVM184VK101H, V106M, V179D, F227LV35T, T39G, D123S, S162SC, K173A, T200A, Q207E, R211RK, V245QC
  2691KC423789D4T, 3TCEFVK70KR, M184VK101H, V106M, V179D, F227LV35T, T39G, K122E, D123S, R125RK, S162C, K173A, T200A, Q207E, F214FL, V245QC
 9092082KC423606D4T, 3TCEFVM184VK101H, Y188L, G190GAV35K, T39E, S48T, V60I, K122E, D123G, K173T, D177E, T200A, Q207K, F214FL, V245Q, D250DEC
 875267KC423775D4T, 3TCEFVM184V, T215FK101H, V106M, P225H, M230LV35T, T39E, K122E, T139AV, K173A, Q174K, D177E, E203D, Q207E, R211K, V245K, D250EC
 3941409KC423131D4T, 3TCEFVM184VK101H, G190ST27S, V35R, T39E, S48T, K122E, D123G, S162C, K173I, Q174K, T200A, Q207E, R211K, K238R, V245QC
 333794KC424282D4T, 3TCEFVM184VK101H, K103N, G190AE6D, V35T, T39E, S48T, K122E, D123S, K173R, Q174K, G196R, T200A, Q207E, V245K, E248NC
 1110655KC424206D4T, 3TCEFVA62V, M184VK101H, G190SE6K, V35T, T39E, K122E, I142V, K173T, Q174R, D177E, I178L, T200A, Q207E, V245EC
 17772833KC423847TDF, 3TCNVPK65R, M184VK101H, Y181C, G190AV35T, E36A, T39D, S48T, E53D, K122E, D123G, S162C, K173A, Q174K, D177E, I178L, T200A, K201KR, Q207E, R211K, F214FL, V245Q, D250EC
 53599KC424419D4T, 3TCEFVM184VK101H, V106M, G190AE6KT, K11KR, K32KR, V35T, E36A, T39E, S48T, K122E, T165I, K173A, D177E, T200A, Q207E, F214L, V245K, A272P, Q278H, T286A, E291D, V292I, I293V, I326V, Q334EC
 185648KC424199D4T, 3TCEFVM184V, T215VK101H, V179E, Y188LV35T, E36A, T39D, S48T, K122E, D123N, E138A, V148VA, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, P243T, V245Q, E248DC
  1219KC422970D4T, 3TCEFVM184V, T215FK101H, V179E, Y188LV35T, E36A, T39D, S48T, K49R, K122E, D123N, I135IT, E138A, E169Q, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LC
 426159KC423251AZT, 3TCNVPD67DN, K70KR, M184V, T215TFISK101H, V106M, Y181CV35T, E36A, T39E, S48T, K122E, D123S, T139L, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q, E248D, K249KRC
Steegen (2014)12ZAKS27412ZAKS274KJ176553D4T, 3TCEFVL74V, M184V, T215YK101H, K103N, G190AV35M, E36A, T39E, S105A, K122E, D123N, A158S, K173T, T200A, Q207D, V245E, A272P, K277R, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359TC
 10ZAKS04210ZAKS042KJ176324D4T, 3TCEFVA62V, M184VK101H, V106M, F227LV35T, T39E, S48T, V90I, A98S, D121H, K122E, I135IT, K166R, K173T, Q174QR, D177E, I178L, T200A, Q207E, R211K, D250E, A272P, K277R, T286A, E291A, V292I, I293VC
 12ZAKS32712ZAKS327KJ176606D4T, 3TCEFVM184VK101H, G190SP4PT, E6KR, V35T, E36A, T39E, W88S, K122E, I135V, K173KT, T200A, Q207E, F214FL, K277KR, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, G359T, T369V, E370EG, T377M, K390R, A400T, E404D, E413GC
Wallis (2014)4145041450KM458524NRTINNRTIM41L, D67N, T69D, K70R, M184V, T215F, K219QA98G, K101H, V106M, Y181C, G190AV35K, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, T165V, K173A, D177E, T200V, I202IV, Q207E, R211K, F214L, L228HC
Skhosana (2015)12ZALS15612ZALS156KM115770D4T, 3TCNVPM41L, D67N, V75I, M184V, T215YK101H, V106M, F227LK20R, L34I, V35T, T39E, L109I, K122E, D123S, E138A, S162C, K173A, Q174K, D177E, V179I, T200A, I202T, Q207D, R211K, H221Y, V245Q, E248N, D250E, A272P, K275R, E291D, V292I, I293V, V314A, Q334N, G335D, R356K, M357T, G359T, K366R, A376AST, T377Q, S379C, K390R, A400T, E404D, K431TC
 12ZALS14112ZALS141KM115780D4T, 3TCNVPM184VK101H, Y181C, G190AV35T, T39K, K43E, S48T, V60I, K122E, D123G, T139K, K173A, Q174K, T200A, Q207E, R211RK, F214L, D218E, L228HR, V245Q, E248V, A272P, K277R, T286A, E291D, V292I, Q334N, G335D, R356K, G359T, V365I, A376G, T377L, K390R, A400L, T403KR, E404DC
 12ZALS09512ZALS095KM115764D4T, 3TCEFVD67N, T69D, K70R, V75T, M184V, K219QK101H, V106M, V179D, G190AK20R, V35T, T39E, S48T, V60I, K122E, D123DN, I135T, E138A, S162F, T165L, K173A, Q174K, N175Y, D177E, T200E, E203K, Q207E, R211K, F214L, D218E, L228N, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297AC